Development and usability testing of an online platform for provider training and implementation of cognitive-behavioral therapy guided self-help for eating disorders by Laura D’Adamo, Agatha A. Laboe, Jake Goldberg, Carli P. Howe, Molly Fennig Steinhoff, Bianca DePietro, Marie-Laure Firebaugh, Zafra Cooper, Denise E. Wilfley, Ellen E. Fitzsimmons-Craft

“…Methods Nine mental health provider participants (n = 4 in Cycle 1; n = 5 in Cycle 2) and 9 patient participants (n = 4 in Cycle 1; n = 5 in Cycle 2) were enrolled over two cycles of usability testing. In Cycle 1, we recruited providers and patients separately to complete brief platform testing sessions. …”
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Reduced white matter integrity and disrupted brain network in children with type 2 and 3 spinal muscular atrophy by Huirong Nie, Shasha Lan, Huan Wang, Pei Xiang, Mengzhen Yan, Yang Fan, Wanqing Shen, Yijuan Li, Wen Tang, Zhiyun Yang, Yujian Liang, Yingqian Chen

“…Methods Forty-two type 2 and 3 pediatric SMA patients and 42 age- and gender-matched healthy controls (HC) were prospectively enrolled in this study. The tract-based spatial statistics (TBSS) was used to assess white matter integrity and the structural network properties were calculated based on DTI white matter fiber tracking and the graph theory approach. …”
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Adjuvant endocrine therapy with cyclin-dependent kinase 4/6 inhibitor, ribociclib, for localized hormone receptor-positive/HER2– breast cancer (LEADER) by Laura M. Spring, Lauren Scarpetti, Arielle J. Medford, Andrzej Niemierko, Amy Comander, Therese Mulvey, Lowell Schnipper, Steven J. Isakoff, Beverly Moy, Seth A. Wander, Jennifer Shin, Zanta Ephrem, Anneke R. Laposta, Elyssa Denault, Elizabeth Abraham, Gayle Calistro, Ekaterina Kalashnikova, Angel Rodriguez, Minetta C. Liu, Alexey Aleshin, Jeffrey Peppercorn, Leif W. Ellisen, Aditya Bardia

“…Recurrence free survival (RFS) and circulating tumor DNA (ctDNA) detection were also evaluated. 81 patients were enrolled. Only six serious adverse events occurred, with no significant difference between treatment arms and no subject deaths. …”
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PPARG2 Pro12Ala and TNFα -308G>A Polymorphisms Are Not Associated with Heart Failure Development in Patients with Ischemic Heart Disease after Coronary Artery Bypass Grafting by Izabela Wojtkowska, Tomasz A. Bonda, Andrzej Tysarowski, Katarzyna Seliga, Janusz A. Siedlecki, Maria M. Winnicka, Janina Stępińska

“…Methods. 122 patients without HF (aged 63 ± 8.8 years, 85% males) with confirmed coronary artery disease qualified for coronary bypass grafting were enrolled in the study. After the procedure, they were screened for cardiac parameters. …”
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Venetoclax plus low-intensity chemotherapy for adults with acute lymphoblastic leukemia by Marlise R. Luskin, Shai Shimony, Julia Keating, Eric S. Winer, Jacqueline S. Garcia, Richard M. Stone, Elias Jabbour, Yael Flamand, Kristen Stevenson, Jeremy Ryan, Zhihong Zeng, Anthony Letai, Marina Konopleva, Nitin Jain, Daniel J. DeAngelo

“…This phase 1b study of venetoclax plus attenuated chemotherapy enrolled 19 patients with ALL either newly diagnosed (aged ≥60 years, n = 11 [B-cell, n = 8; T-cell, n = 3]) or relapsed/refractory (R/R; aged ≥18 years, n = 8 [B-cell, n = 3; T-cell, n = 5]). …”
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Oxygenation improvement and duration of prone positioning are associated with ICU mortality in mechanically ventilated COVID-19 patients by Silvia De Rosa, Nicolò Sella, Giacomo Bellani, Giuseppe Foti, Andrea Cortegiani, Giulia Lorenzoni, Dario Gregori, Annalisa Boscolo, Lucia Cattin, Muhammed Elhadi, Giorgio Fullin, Eugenio Garofalo, Leonardo Gottin, Alberto Grassetto, Salvatore Maurizio Maggiore, Elena Momesso, Mario Peta, Daniele Poole, Roberto Rona, Ivo Tiberio, Andrea Zanoletti, Emanuele Rezoagli, Paolo Navalesi, for the SIAARTI Study Group

“…We measured the difference for arterial partial pressure of oxygen to inspired fraction of oxygen ratio (PaO2/FiO2), ventilatory ratio, and respiratory system compliance (Crs) between baseline supine position and at either the end of the first cycle of prone position (Delta-PP) or re-supination (Delta-PostPP). Results We enrolled 1816 patients from 53 centers. Delta-PP and Delta-PostPP for PaO2/FiO2 were both associated with ICU mortality [OR (95% CI) 0.48 (0.38, 0.59), and OR (95% CI) 0.60 (0.52, 0.68), respectively]. …”
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Exercise-based cardiac rehabilitation for patients with atrial fibrillation receiving catheter ablation: protocol for a feasibility randomised controlled trial (RCT) with embedded... by Gregory Y H Lip, Helen Jones, Mark T Mills, Dhiraj Gupta, Lawrence Foweather, Benjamin JR Buckley, Charlotte Fitzhugh

“…The trial (n=60) will involve one National Health Service (NHS) research site enrolling patients to assess intervention and study design processes. …”
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Precise Detection of Gene Mutations in Fine-Needle Aspiration Specimens of the Papillary Thyroid Microcarcinoma Using Next-Generation Sequencing by Feng-xia Yu, Min-xia Hu, Han-xue Zhao, Li-juan Niu, Xue-yu Rong, Wei-hua Li, Qiang Zhu, Jian-ming Ying, Ning Lyu

“…Of those 114 samples, 72 who were confirmed as having PTMC by postoperative histopathology were enrolled in our study, and the other 42 who had a follow-up with ultrasound were excluded. …”
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Initial treatment of steroid-sensitive idiopathic nephrotic syndrome in children with mycophenolate mofetil versus prednisone: protocol for a randomised, controlled, multicentre tr... by Burkhard Toenshoff, Martin Konrad, Steffen Luntz, Anja Sander, Peter F Hoyer, Rasmus Ehren, Marcus R Benz, Jorg Doetsch, Alexander Fichtner, Jutta Gellermann, Dieter Haffner, Britta Höcker, Bärbel Kästner, Markus J Kemper, Uwe Querfeld, Lutz T Weber

“…The aim of the INTENT study (Initial treatment of steroid-sensitive idiopathic nephrotic syndrom in children with mycophenolate mofetil versus prednisone: protocol for a randomised, controlled, multicentre trial) is to show that an alternative treatment regimen with mycophenolic acid is not inferior regarding sustainment of remission, but with lower toxicity compared with treatment with glucocorticoids only.Methods and design The study is designed as an open, randomised, controlled, multicentre trial. 340 children with a first episode of steroid-sensitive nephrotic syndrome and who achieved remission by a standard prednisone regimen will be enrolled in the trial and randomised to one of two treatment arms. …”
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Impact of Prophylactic Use of PEG-rhG-CSF on First-Line Immunochemotherapy in Advanced NSCLC: A Cohort Study by Li Sun, MD, Yuan Tian, MD, Shuling Zhang, MD, PhD, Letian Huang, MD, Jietao Ma, MD, PhD, Chengbo Han, MD, PhD

“…Results: A total of 220 patients were enrolled, with 87 in the treatment group and 133 in the control group. …”
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Effect of arm-ergometry versus treadmill supervised exercise on health-related quality of life and mental health in patients with peripheral artery disease: secondary outcomes from... by Sandra Magalhães, Mário Santos, Sofia Viamonte, Fernando Ribeiro, Joana Martins, Cristine Schmidt, Henrique Cyrne-Carvalho

“…Methods This was an ancillary study of the ARMEX trial, a single-center, single-blinded, parallel group, randomized clinical trial, enrolling symptomatic PAD patients referred to a cardiovascular rehabilitation program (CRP). …”
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Impact of Thrombocytopenia on In-Hospital Outcome in Patients Undergoing Percutaneous Coronary Intervention by Zhongxiu Chen, Zheng Liu, Nan Li, Ran Liu, Miye Wang, Duolao Wang, Chen Li, Kai Li, Fangbo Luo, Yong He

“…Results. Of 9531 patients enrolled in our study, 936 had baseline thrombocytopenia and 8595 patients did not have. …”
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Liver Imaging and Data System (LI-RADS) Version 2018 and Other Imaging Features in Intrahepatic Cholangiocarcinoma in Chinese Adults with vs. without Chronic Hepatitis B Viral Infe... by Ying-ying Liang, Shuo Shao, Sichi Kuang, Jingbiao Chen, Jing Zhou, Bingjun He, Linqi Zhang, Yao Zhang, Kathryn J. Fowler, Jin Wang

“…Methods. We retrospectively enrolled 89 patients with pathologically proven iCCA after multiphase imaging performed between 2004 and 2017 at a tertiary medical center in southern China. …”
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Association between red blood cell distribution width and genetic risk in patients with rheumatoid arthritis: a prospective cohort study and Mendelian randomization analysis by Mingyang Chen, Jing Lei, Zhenqiu Liu, Renjia Zhao, Yanfeng Jiang, Kelin Xu, Tiejun Zhang, Chen Suo, Xingdong Chen

“…Results A total of 675 patients with RA were enrolled and had a median followed up of 5.1 years, with an incidence rate of 0.57/1000 person-years. …”
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Comparing Antibody Responses to Homologous vs. Heterologous COVID-19 Vaccination: A Cross-Sectional Analysis in an Urban Bangladeshi Population by Kazi Istiaque Sanin, Mansura Khanam, Azizur Rahman Sharaque, Mahbub Elahi, Bharati Rani Roy, Md. Khaledul Hasan, Goutam Kumar Dutta, Abir Dutta, Md. Nazmul Islam, Md. Safiqul Islam, Md. Nasir Ahmed Khan, Mustufa Mahmud, Nuzhat Nadia, Fablina Noushin, Anjan Kumar Roy, Protim Sarker, Fahmida Tofail

“…Methods: This cross-sectional study enrolled 723 adults in urban Dhaka who had received COVID-19 booster doses within the last six months. …”
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Surgical Treatment of Idiopathic Macular Hole Using Different Types of Tamponades and Different Postoperative Positioning Regimens by M. Veith, J. Vránová, J. Němčanský, J. Studnička, M. Penčák, Z. Straňák, P. Mojžíš, P. Studený, D. P. Piñero

“…Prospective randomized clinical trial enrolling 104 eyes of 100 patients (age, 57–87 years) undergoing MH surgery. …”
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Solid Indeterminate Pulmonary Nodules Less Than or Equal to 250 mm3: Application of the Updated Fleischner Society Guidelines in Clinical Practice by Andrea Borghesi, Silvia Michelini, Giorgio Nocivelli, Mario Silva, Alessandra Scrimieri, Stefania Pezzotti, Roberto Maroldi, Davide Farina

“…Applying these criteria, a total of 27 patients with single SIPNs ≤ 250 mm3 were enrolled. For each SIPN, the volume and doubling time were calculated using semiautomatic software throughout the follow-up period. …”
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Pembrolizumab, radiotherapy, and an immunomodulatory five-drug cocktail in pretreated patients with persistent, recurrent, or metastatic cervical or endometrial carcinoma: Results... by Emiel A. De Jaeghere, Sandra Tuyaerts, An M. T. Van Nuffel, Ann Belmans, Kris Bogaerts, Regina Baiden-Amissah, Lien Lippens, Peter Vuylsteke, Stéphanie Henry, Xuan Bich Trinh, Peter A. van Dam, Sandrine Aspeslagh, Alex De Caluwé, Eline Naert, Diether Lambrechts, An Hendrix, Olivier De Wever, Koen K. Van de Vijver, Frédéric Amant, Katrien Vandecasteele, Hannelore G. Denys

“…The prespecified 43 patients (cervical, n = 18; endometrial, n = 25) were enrolled. The irORR was 11.1% (90% CI 2.0–31.0) in cervical cancer and 12.0% (90% CI 3.4–28.2) in endometrial cancer. …”
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The influencing factors of the erythropoietin resistance index and its association with all-cause mortality in maintenance hemodialysis patients by Xinju Zhao, Liangying Gan, Fan Fan Hou, Xinling Liang, Xiaonong Chen, Yuqing Chen, Zhaohui Ni, Li Zuo

“…This study aimed to investigate the influencing factors of erythropoietin resistance index (ERI) and its association with mortality in maintenance hemodialysis (MHD) patients. Patients enrolled from China Dialysis Outcomes and Practice Patterns Study (DOPPS) 5 were included. …”
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Vδ2 T-cells response in people with Mpox infection: a three-month longitudinal assessment by Eleonora Cimini, Eleonora Tartaglia, Francesco Messina, Andrea Coppola, Valentina Mazzotta, Massimo Tempestilli, Giulia Matusali, Stefania Notari, Annalisa Mondi, Gianluca Prota, Alessandra Oliva, Carla Fontana, Enrico Girardi, Fabrizio Maggi, Andrea Antinori

“…Fourteen MSM subjects (5 PWH, 35.7%) were enrolled in a longitudinal study from May to July 2022. …”
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