Nomograms for predicting recurrence of HER2‐positive breast cancer with different HR status based on ultrasound and clinicopathological characteristics by Xudong Zhang, Hanqing Kong, Xiaoxue Liu, Qingxiang Li, Xinran Fang, Junjia Wang, Zihao Qin, Nana Hu, Jiawei Tian, Hao Cui, Lei Zhang

“…Methods In this dual‐center study, we retrospectively enrolled 570 patients with HER2+ breast cancer. The ultrasound and clinicopathological characteristics of hormone receptor (HR)−/HER2+ patients and HR+/HER2+ patients were analyzed separately according to HR status. …”
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Factors associated with oxidative stress in virologically suppressed people living with HIV on long-term antiretroviral therapy by Francesca Lombardi, Simone Belmonti, Alessia Sanfilippo, Alberto Borghetti, Valentina Iannone, Pierluigi Francesco Salvo, Massimiliano Fabbiani, Elena Visconti, Simona Di Giambenedetto

“…Factors associated with OS markers were explored by linear regression model. Results We enrolled 299 experienced PLWH with virological suppression (HIV-RNA < 50cps/mL). …”
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The CD4/CD8 ratio is associated with T lymphocyte functions in long-term virally suppressed patients with HIV by Qing Xiao, Fengting Yu, Liting Yan, Xiaojie Lao, Xuelei Liang, Hongxin Zhao, Liuyue Zhai, Zailin Yang, Xiaomei Zhang, Yao Liu, Fujie Zhang

“…Methods 125 PLWHs and 31 HIV-uninfected controls (UCs) were enrolled and categorized into four groups based on their CD4/CD8 ratios: extremely low ratio (ELR) group: 0.4 < CD4/CD8; low ratio (LR) group: 0.4 ≤ CD4/CD8<0.7; medium ratio (MR) group: 0.7 ≤ CD4/CD8<1; high ratio (HR) group: CD4/CD8 ≥ 1. …”
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Sagittal Inclination Angle of the Graft Affects Graft Maturity and Knee Stability After Anterior Cruciate Ligament Reconstruction by Ming Li, Fangang Meng, Dianbo Long, Dorje Wencheng, Yanlin Zhong, Yan Kang, Peihui Wu, Aishan He

“…Results Sixty‐three postoperative patients were enrolled. The SIA was significantly negatively associated with graft SNQ value. …”
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Value of Assessing Autonomic Nervous Function by Heart Rate Variability and Heart Rate Turbulence in Hypertensive Patients by Yijun Yu, Yanling Xu, Mingjing Zhang, Yuting Wang, Wusong Zou, Ye Gu

“…A total of 120 consecutive hypertensive patients and 80 nonhypertensive patients (N-HP group) were enrolled in this study. The hypertensive patients were divided into controlled blood pressure and uncontrolled blood pressure groups according to their blood pressure on admission. …”
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Interrelation between hypoxic liver injury and Killip classification in ST-segment elevation myocardial infarction patients by Seong Huan Choi, Ji-Hun Jang, Dae-Young Kim, Young Ju Suh, Yong-Soo Baek, Sung-Hee Shin, Seong-Ill Woo, Dae-Hyeok Kim, Jeonggeun Moon, Jon Suh, WoongChol Kang, Sang-Don Park, Sung Woo Kwon

“…This study investigates the interrelationship between hypoxic liver injury (HLI) and Killip classification.Method and resultsA total of 1,537 STEMI patients who underwent percutaneous coronary intervention (PCI) from 2007 to 2014 at four tertiary hospitals in the Incheon-Bucheon province were enrolled in this study. The patients were divided into four groups based on their Killip classification at presentation in the emergency room (ER). …”
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Feasibility analysis of non-electrocardiogram-triggered chest low-dose computed tomography using a kV-independent reconstruction algorithm for predicting cardiovascular disease ris... by Xiangming Wang, Ao Liu, Yan Zhao, Xianbo Yu, Yushuo Cao, Min Li, Jing Liu, Yu Du, Li Yang

“…Excluding those scanned at 120 kV, 172 patients were enrolled. Although the ASs of non-ECG-triggered LDCT were lower than those of the standard CACS, the agreement and correlation of ASs of the two scans were excellent, and both intraclass correlation coefficients (ICCs) and Pearson’s correlation coefficients were > 0.96. …”
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Knowledge, behaviour and attitudes towards Chagas disease among the Bolivian migrant population living in Japan: a cross-sectional study by Chris Smith, Kenji Hirayama, Nguyen Tien Huy, Inés María Iglesias Rodríguez, Dao Huy Manh, Tieu Minh Thuan, Hugo Alberto Justiniano, Sachio Miura, George Ito

“…Fifty-nine of them participated in the EA.Interventions The EA comprised showing three videos about CD and a group discussion covering different dimensions of CD and was evaluated with questionnaires to analyse the knowledge of the participants before and after.Results Seventy-two participants were enrolled, predominantly from highly endemic CD areas of Bolivia. …”
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Development an Inflammation-Related Factor-Based Model for Predicting Organ Failure in Acute Pancreatitis: A Retrospective Cohort Study by Yunpeng Peng, Xiaole Zhu, Chaoqun Hou, Chenyuan Shi, Dongya Huang, Zipeng Lu, Yi Miao, Qiang Li

“…Methods. 100 patients with their clinical information and IRF data (levels of 10 cytokines, percentages of different immune cells, and data obtained from white blood cell count) were retrospectively enrolled in this study, and 94 patients were finally selected for further analysis. …”
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Exploring fatigue in Marfan and hypermobile Ehlers-Danlos syndromes: an analytical cross-sectional study in two Italian healthcare centres by Rosario Caruso, Alessandro Pini, Gianluca Conte, Arianna Magon, Irene Baroni, Edward Callus, Nathasha Udugampolage, Jacopo Taurino, Alessandra Bassotti, Giada De Angeli, Giulia Paglione, Giuliana Trifirò

“…Objective This study investigates the prevalence and underlying factors of fatigue in individuals with Marfan syndrome (MFS) and hypermobile Ehlers-Danlos syndromes (hEDS), highlighting the necessity for focused research on this symptom within these patient populations.Design Cross-sectional, multicentre study.Setting Data were collected from participants diagnosed with MFS or hEDS across multiple healthcare centres.Participants The study enrolled 282 participants (127 with MFS and 155 with hEDS).Primary and secondary outcome measures Fatigue was measured using the Fatigue Severity Scale (FSS). …”
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Hepatic arterial infusion chemotherapy combined with systemic therapy sequentially or simultaneously for advanced hepatocellular carcinoma by Yu-zhe Cao, Jia-yu Pan, Guang-lei Zheng, Chao An, Meng-Xuan Zuo

“…Approach and results From January 1, 2018, to June 1, 2022, 575 patients with BCLC stage C HCC who underwent SE or SI triple therapy were retrospectively enrolled. Propensity score matching (PSM; 1:1) was performed to eliminate possible confounder imbalances across cohorts. …”
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Effects of trimester-specific urinary aluminum concentrations on ultrasound measures of fetal growth and size at birth: A longitudinal cohort study in Chinese women by Haiying Chen, Wenjing Yan, Xueyan Wu, Yuanyuan Li

“…Methods: Between 2013 and 2016, 3599 women from Wuhan, China were enrolled in the prospective cohort study. The concentrations of Al were quantified in urine samples obtained from pregnant women during the 1st, 2nd and 3rd trimesters by inductively coupled plasma mass spectrometry. …”
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Mechanical chest compression increases intrathoracic hemorrhage complications in patients receiving extracorporeal cardiopulmonary resuscitation by Yoshihisa Matsushima, Tatsuhiro Shibata, Kodai Shibao, Rei Yamakawa, Miyu Hayashida, Toshiyuki Yanai, Takashi Ishimatsu, Takehiro Homma, Shoichiro Nohara, Maki Otsuka, Yoshihiro Fukumoto

“…Results: A total of 91 patients were enrolled (mechanical n = 48, manual n = 43). Intrathoracic hemorrhage requiring TAE occurred more frequently in the mechanical CPR group (18.8% vs. 2.3%, p = 0.030). …”
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Colonic Mucosal Microbiota in Colorectal Cancer: A Single-Center Metagenomic Study in Saudi Arabia by Ahmed O. Alomair, Ibrahim Masoodi, Essam J. Alyamani, Abed A. Allehibi, Adel N. Qutub, Khalid N. Alsayari, Musaad A. Altammami, Ali S. Alshanqeeti

“…From July 2010 to November 2012, colorectal cancer patients attending our hospital were enrolled for the metagenomic studies. All underwent clinical, endoscopic, and histological assessment. …”
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Association of neutrophil-to-lymphocyte ratio with severe abdominal aortic calcification: new evidence from the United States by Hao Deng, Mengmeng Sun, Zhentong Zhao, Kun Fan, Zizhang Zhao, Yifan Chi, Wei Sheng

“…Multivariable logistic regression, stratified analysis with interaction, and restricted cubic spline analysis were used to examine the relationship between the NLR and AAC.ResultsThis study enrolled 3,047 participants [1,469 men (48.2%) and 1,578 women (51.8%)]. …”
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Cardiovascular Protection of Nephropathic Male Patients by Oral Food Supplements by Annalisa Noce, Giulia Marrone, Manuela Di Lauro, Silvia Urciuoli, Anna Pietroboni Zaitseva, Georgia Wilson Jones, Nicola Di Daniele, Annalisa Romani

“…In this study, 23 male nephropathic patients and 10 age and body composition parameter matched healthy males (control group) were enrolled and took 3 cps/day of OFS for 5 weeks. At the end of the study, the nephropathic patient group showed a statistically significant reduction in the following laboratory parameters: total cholesterol (TC) (p=0.044), atherogenic index TC/high-density lipoprotein cholesterol (p=0.010), inflammatory parameters (C-reactive protein, p=0.048, and erythrocyte sedimentation rate, p=0.019), systolic (p=0.044), and diastolic arterial blood pressure (p=0.003). …”
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Brief Mindfulness-Based Cognitive Therapy in Women With Myocardial Infarction by Tanya M. Spruill, PhD, Chorong Park, PhD, RN, Jolaade Kalinowski, EdD, Milla E. Arabadjian, PhD, RN, Yuhe Xia, MSc, Amanda J. Shallcross, ND, MPH, Pallavi Visvanathan, PhD, Nathaniel R. Smilowitz, MD, MS, Anaïs Hausvater, MD, Sripal Bangalore, MD, MHA, Hua Zhong, PhD, Ki Park, MD, Puja K. Mehta, MD, Dwithiya K. Thomas, MD, Jeffrey Trost, MD, Kevin R. Bainey, MD, Bobak Heydari, MD, Janet Wei, MD, Victoria Vaughan Dickson, PhD, RN, Gbenga Ogedegbe, MD, MPH, Jeffrey S. Berger, MD, MS, Judith S. Hochman, MD, Harmony R. Reynolds, MD

“…Methods: Women with elevated stress (Perceived Stress Scale [PSS-4]≥6) at least 2 months after MI were enrolled from 12 hospitals in the United States and Canada and via community advertising. …”
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Safety and efficacy of trifluridine/tipiracil +/− bevacizumab plus XB2001 (anti-IL-1α antibody): a single-center phase 1 trial by Marion Thibaudin, Nicolas Roussot, Chloé Burlot, Antonin Schmitt, Julie Vincent, Zoé Tharin, Leila Bengrine, Hélène Bellio, Aurélie Bertaut, Léa Hampe, Susy Daumoine, Emilie Rederstorff, Morgane Peroz, Titouan Huppe, Valentin Derangère, David Rageot, John Simard, Caroline Truntzer, Jean David Fumet, Francois Ghiringhelli

“…Seventeen patients (median age: 67.4 years) were enroled. No patient exhibited dose-limiting toxicity at any dose. …”
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Multicentre, 26-week, open-label phase 2 trial of the JAK inhibitor filgotinib in Behçet’s disease, idiopathic inflammatory myopathies and IgG4-related disease: DRIMID study protoc... by Sander W Tas, Joost Raaphorst, Paco M J Welsing, Jacob M van Laar, Rogier M Thurlings, Robbert J Goekoop, César Magro Checa, Jan A M van Laar, Bettina C Geertsema-Hoeve, Nicolle H Rekers, Erik Present

“…The Drug Rediscovery in IMIDs (DRIMID) consortium aims to conduct a prospective pilot basket trial to investigate the effects of filgotinib, a JAK1 preferential inhibitor approved for ulcerative colitis and rheumatoid arthritis, on disease activity, quality of life and safety in patients with refractory BD, IIM and IgG4-RD.Methods and analysis In this investigator-initiated, multicentre, open-label phase 2 study, up to 60 patients with rare IMIDs will be enrolled for a 26-week treatment period with filgotinib 200 mg once daily. …”
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HDL proteome and apolipoproteins concentrations in severe ICU COVID-19 patients by Floran Begue, Bryan Veeren, Philippe Rondeau, Aline-Marie Florence, Simon Jamard, Philippe Montravers, Sébastien Tanaka, Olivier Meilhac, on behalf of French COVID Study Group

“…Methods Between February and April 2020, our study enrolled 37 COVID-19 patients upon their intensive care unit admission. …”
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