FARKLI TİPTEKİ RESTORATİF CAM İYONOMER SİMANLARIN MİKROSIZINTI ÜZERİNE ISI UYGULANMASININ ETKİSİ by Çiğdem Güler, Fatih Bayar

“…Gereç ve Yöntemler: Çalışma için toplam 112 adet çürüksüz süt ikinci azı dişinin hem bukkal hem de lingual/palatinal yüzeylerine standart sınıf V kaviteler (4X2X2 mm) açılmış ve dört farklı tipteki restoratif cam iyonomer siman [geleneksel cam iyonomer (GC Fuji IX), rezin modifiye cam iyonomer (GC Fuji II LC), yüksek viskoziteli cam iyonomer (GC EQUIA Fil) ve cam karbomer (GCP Glass Fill)] ile restorasyonlar yapılmıştır. …”
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Performance analysis of Leica Biosystems p16 monoclonal antibody in oropharyngeal squamous cell carcinoma by Selvam Thavaraj, Max Robinson, Shubham Dayal, Claire Bowen

“…Leica Biosystems (LBS) has developed a p16 antibody (6H12 clone) for qualitatively identifying the p16 protein in formalin-fixed paraffin-embedded (FFPE) tissue by immunohistochemical staining. …”
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Człowiek i przyroda w nauce chrześcijańskiego Wschodu by Janusz Aptacy

“…But man, because of original sin, has led to a true cosmic catastrophe, to a darkening of the modality of paradise and to the appearance of a new way of universal existence, marked by sin. …”
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Tracking hydrothermal infiltration within light oil reservoirs using organic geochemical proxies in the Shunbei area of Tarim Basin in China by Jian Gao, Shaojie Li, Huan Li, Zicheng Cao, Huili Li, Feng Geng, Jun Han, Cheng Huang

“…The studied crude oils are characterized by uniform organic indicators of paraffin, terpanes, steranes, and light hydrocarbons, implying that crude oils are derived from the same source rock. …”
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Personality characteristics of students in the regulation of network activity by S. E. Panshina, N. L. Sungurova, N. B. Karabushchenko

“…Gritsenko; the technique of M. Kernis and A. Paradise “The Contingent Self-Esteem Scale” adapted by T. …”
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Pathological variants in HPV-independent vulvar tumours by Sanja A. Farkas, Alvida Qvick, Gisela Helenius, Gabriella Lillsunde-Larsson

“…The study included formalin-fixed paraffin-embedded (FFPE) samples from 32 cancer patients (16 HPV-negative and 16 HPV-associated), treated in Örebro, Sweden from 1988 to 2008. …”
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'Giustizia fatta': observations sur un registre des condamnés à mort (1471–1764) de la bibliothèque de Beccaria by Pierre Musitelli

“…En un mot, lire le registre des condamnés permet de comprendre dans quel terreau s’enracine l’humanitarisme pénal qui fut une composante essentielle de l’histoire intellectuelle des lumières italiennes.…”
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Renovatio imperii Romani: The aspect of Christian wored outlook by Marius Ščavinskas

“…Only after the Last Judgment will it become clear where which soul will be going—to hell or paradise. Only good behavior and good works dedicated to soul and body helped people to achieve eternal life. …”
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Beclin-1 as a potential prognostic marker in correlation with E-cadherin in oral lichen planus and oral squamous cell carcinoma: an immunohistochemical analysis by Heba N. Shalash, Radwa R. Hussein, Fatma Seragel-Deen

“…Sixty formalin-fixed paraffin-embedded tissue blocks, along with their clinicopathologic records, were retrieved from the archives of the Department of Oral Pathology, Faculty of Dentistry, Ain Shams University, Egypt. …”
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Pleomorphic Adenoma in Palatal Region of a Young Patient: A Case Report by Adel Sharifi Rayeni, Arian Yeganeh

“…The lesion did not destroy the palatine bone and did not invade the maxillary sinus. …”
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ALTERNATYVI MODERNYBĖ IR JOS STRATEGIJOS by Arūnas Gelūnas

“… Straipsnyje svarstomas modernybės fenomenas bei pamatinės moderniosios filosofijos ir humanitarinių mokslų nuostatos, susilaukiančios radikalios nūdienos mąstytojų kritikos: atotrūkis tarp faktų ir vertybių, bendruomenę jungiančių saitų susilpnėjimas, mokslinės-technologinės sistemos susiformavimas ir dėl to kylantys svarbūs individų savivokos pokyčiai. …”
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Programmed Cell Death Ligand 1 (PD-L1) and major Histocompatibility Complex Class I (MHC Class I) Expression Patterns and Their Pathologic Associations in triple-Negative Breast Ca... by Kaewkedsri P, Intarawichian P, Jessadapattarakul S, Kunprom W, Koonmee S, Thanee M, Somintara O, Wongbuddha A, Chadbunchachai P, Nawapun S, Aphivatanasiri C

“…Ponkrit Kaewkedsri,1 Piyapharom Intarawichian,1 Sirawich Jessadapattarakul,1 Waritta Kunprom,1 Supinda Koonmee,1 Malinee Thanee,1 Ongart Somintara,2 Anongporn Wongbuddha,2 Payia Chadbunchachai,3 Supajit Nawapun,3 Chaiwat Aphivatanasiri1 1Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand; 2Department of Surgery, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand; 3Department of Radiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, ThailandCorrespondence: Chaiwat Aphivatanasiri, Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand, Email chaiap@kku.ac.thPurpose: This study aims to investigate the clinicopathological characteristics of triple-negative breast cancer (TNBC) in relation to programmed cell death ligand 1 (PD-L1) and major histocompatibility complex class I (MHC class I) expression, with a focus on their prognostic significance.Patients and Methods: A retrospective analysis was conducted on formalin-fixed paraffin-embedded (FFPE) tissue samples from 148 TNBC patients diagnosed between 2008 and 2021. …”
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Whether Detection of Gene Mutations Could Identify Low- or High-Risk Papillary Thyroid Microcarcinoma? Data from 393 Cases Using the Next-Generation Sequencing by Lei Jin, Liang Zhou, Jian-Biao Wang, Li Tao, Xiao-Xiao Lu, Na Yan, Qian-Ming Chen, Li-Ping Cao, Lei Xie

“…NGS was used to analyze 393 formalin-fixed, paraffin-embedded tissues of PTC tumors, all of which were smaller than 15 mm. …”
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ALTERNATYVI MODERNYBĖ IR JOS STRATEGIJOS by Arūnas Gelūnas

“… Straipsnyje svarstomas modernybės fenomenas bei pamatinės moderniosios filosofijos ir humanitarinių mokslų nuostatos, susilaukiančios radikalios nūdienos mąstytojų kritikos: atotrūkis tarp faktų ir vertybių, bendruomenę jungiančių saitų susilpnėjimas, mokslinės-technologinės sistemos susiformavimas ir dėl to kylantys svarbūs individų savivokos pokyčiai. …”
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Effect of Electroacupuncture on Chondrocyte Apoptosis and Cartilage Matrix of Experimental Rats with Knee Osteoarthritis by Guangwen WU, Chunsong ZHENG, Xihai LI, Qiuying LIN, Yichen DAI, Qiuxiang LIN, Yuanyuan ZHANG, Mingxia WU

“…The medial cartilages of right tibial plateau were obtained, and fixed in 4%paraformaldehyde, and embedded in paraffin. TUNEL was performed to assess the chondrocyte apoptosis. …”
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‘Queer Reverence’: Aubrey Beardsley’s Venus and Tannhäuser by Nicole Fluhr

“…Instead, the land ‘under the hill’ is constituted as a genuinely alternative paradise, a counterpublic of perverts who communally flout the dictates of heteronormativity, together constructing a world that does not simply exclude shame, guilt, and sin but disavows them entirely.…”
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SAVASTIES ĮGIJIMO BŪDAI. FOUCAULT IR BACHTINAS APIE GYVENIMO ESTETIZACIJĄ by Leszek Koczanowicz

“…Įvairūs pokantiniai judėjimai savastį laikė pamatine realybe, egzistencijos autentiškumo šaltiniu. …”
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SAVASTIES ĮGIJIMO BŪDAI. FOUCAULT IR BACHTINAS APIE GYVENIMO ESTETIZACIJĄ by Leszek Koczanowicz

“…Įvairūs pokantiniai judėjimai savastį laikė pamatine realybe, egzistencijos autentiškumo šaltiniu. …”
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Features of expression of immunohistochemical markers in local and generalized clear cell kidney cancer by E. M. Frantsiyants, A. N. Shevchenko, E. A. Dzhenkova, N. S. Karnaukhov, T. A. Gudtskova, A. A. Breus, E. V. Filatova, D. A. Shvyrev

“…For the immunohistochemical (IHC) study, the material was fixed in 10% neutral formalin for 24 hours and encased in paraffin. Dewaxing and restoration of antigenic activity of the material was carried out in the RT module (Thermo Fisher Scientific) using Tris buffer pH=9, for 20 minutes at 98 °C. the Formulation of the IGC reaction was carried out in the immunohistostainer «Autostainer 480S» (Thermo Fisher Scientific). …”
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Correlation of the Changes of Gray Matter Volume with Aβ Deposition and Learning and Memory Abilities in APP/PS1 Mice at Different Periods by Yuhao ZHANG, Hao JIN, Xiufeng ZHANG, Shengxiang LIANG, Weilin LIU, Jing TAO, Lidian CHEN

“…The Morris water maze test (including location navigation test and spatial exploration test) was used to detect the spatial memory learning ability and spatial memory extraction ability of the two groups of mice, and the magnetic resonance T2-weighted imaging (MRI T2WI) scan was used to detect the changes of gray matter volume in the bilateral entorhinal cortex and hippocampus of mice. The brain paraffin sections of two groups of mice of different months were separated and prepared, and the Aβ deposition in bilateral entorhinal cortex and hippocampus of the two groups was detected by Thioflavine-s fluorescence staining, and the correlation between the changes of gray matter volume and memory learning ability and Aβ deposition in the corresponding brain area of the two groups was analyzed by Pearson correlation analysis.Results:①The results of Morris water maze test: compared with the WT group, there was no significant difference in the behavioral results of the 2-month-old mice in the APP/PS1 group, and the difference was not statistically significant (<italic>P</italic>&gt;0.05); the escape latency of mice of the APP/PS1 group at the 6 and 12 month-old increased significantly, the number of crossing platforms of the APP/PS1 group at the 6 and 12 month-old decreased significantly, and the difference was statistically significant (<italic>P</italic>&lt;0.05).②The results of MRI T2WI scan: compared with the WT group, there was no significant change in the gray matter volume of the APP/PS1 group at 2-month-old, and the difference was not statistically significant (<italic>P</italic>&gt;0.05); the volume of the entorhinal cortex of the APP/PS1 group at 6-month-old decreased significantly, and the volume of the entorhinal cortex and hippocampus of the APP/PS1 group at 12-month-old mice decreased significantly, the difference was statistically significant (<italic>P</italic>&lt;0.05).③The results of Th-s fluorescence staining test: Aβ deposition was not detected in WT group and APP/PS1 group at 2-month-old; compared with the WT group, a small amount of Aβ deposition could be detected in the entorhinal cortex and hippocampus of the APP/PS1 group at 6-month-old, while a large number of dense Aβ plaques can be detected in the entorhinal cortex and hippocampus of the APP/PS1 group at 12-month-old.④Correlation analysis results: APP/PS1 group mice's entorhinal cortex and hippocampus volume changes were significantly negatively correlated with escape latency (<italic>r</italic>=-0.729, <italic>P</italic>&lt;0.001; <italic>r</italic>=-0.643, <italic>P</italic>&lt;0.001); the volume changes of the entorhinal cortex and hippocampus in the APP/PS1 group showed a positive correlation with the number of crossing platforms (<italic>r</italic>=0.705, <italic>P</italic>&lt;0.001; <italic>r</italic>=0.719, <italic>P</italic>&lt;0.001); the volume changes of the entorhinal cortex and hippocampus in the APP/PS1 group were significantly negatively correlated with Aβ deposition (<italic>r</italic>=-0.865, <italic>P</italic>&lt;0.001; <italic>r</italic>=-0.885, <italic>P</italic>&lt;0.001).Conclusion:APP/PS1 transgenic mice may have learning and memory dysfunction at 6-month-old, and it gradually worsen with time; the learning and memory dysfunction may be related to the atrophy of the entorhinal cortex and hippocampus in the brain of mice, and excessive Aβ deposition may be the one of the factors that cause the brain gray matter volume to shrink.…”
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