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    One-Year Outcomes in Subjects Developing Macular Neovascularization While Undergoing Avacincaptad Pegol Therapy for Geographic Atrophy by Rush RB, Klein W, Rush SW, Reinauer R

    Published 2025-01-01
    “…The Study Group had a greater decrease in visual acuity [− 0.22 logMAR (− 0.27 to − 0.17) versus − 0.06 logMAR (− 0.12 to 0.00); p=< 0.0001], and greater GA total lesion growth [1.78 mm2 (1.53– 2.03) versus 0.78 mm2 (0.54– 1.02); p=< 0.0001] during the 12-month study period compared to the Control Group.Conclusion: Patients developing MNV while undergoing IVA treatment for GA secondary to AMD have worse clinical outcomes despite undergoing anti-VEGF therapy compared to patients who were complication-free at 12-months. …”
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