Upper Pleistocene fauna from the Middle Palaeolithic site of Foz do Enxarrique (Vila Velha de Ródão, Naturtejo Unesco Global Geopark) by Silvério Figueiredo, Luís Raposo, Maria Sousa

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From Flipped Classroom to Flipped Learning: Evolution of the Concept and Its Philosophical Foundations by I. I. Gnutova

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Metodologia das escalas geográficas de poder e gestão aplicada à análise de desenvolvimento em quatro territórios rurais no Brasil by Aldomar A. Rückert, Anelise G. Rambo

“…It is presented here the action scales of actors in four projects developed in rural territories - the Regional Cooperative of Peasant Agriculture (CORAC), Seberi, (“Médio Alto Uruguai” territory /Rio Grande do Sul state); Small Farmers Milk Production Cooperatives Sistem (SISCLAF), Francisco Beltrão (“Sudoeste do Paraná Territory” / Paraná state); Small Peasant Agriculture Formation Center São José Operário (CENTAF), Silvânia, (“Estrada de Ferro” Territory / Goiás state) and Frutivale Association, Datas (“Vale do Jequitinhonha” Territory /Minas Gerais state). …”
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Comprehensive analysis of H3K27me3 LOCKs under different DNA methylation contexts reveal epigenetic redistribution in tumorigenesis by Yuan Liang, Mengni Liu, Bingyuan Liu, Benjamin Ziman, Guanjie Peng, Qiong Mao, Xingzhe Wang, Lizhen Jiang, De-Chen Lin, Yueyuan Zheng

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The enigmatic diploid Chenopodium ucrainicum (Chenopodiaceae / Amaranthaceae s. l.): geographical, ecological, and phytosociological patterns as clues to its origin by Shynder O.I., Pashkevych N.A., Kharytonova I.P., Holovko O.V., Mandák B., Mosyakin S.L.

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Engineered GM-CSF polarizes protumorigenic tumor-associated macrophages to an antitumorigenic phenotype and potently synergizes with IL-12 immunotherapy by Yue Wang, Kevin Chang, Aslan Mansurov, Jun Ishihara, Seounghun Kang, Trevin Kurtanich, Hye Rin Chun, Anna J Slezak, Lisa R Volpatti, Thomas Wang, Aaron T Alpar, Kirsten C Refvik, O Isabella Hansen, Gustavo J Borjas, Brendan T K Berg, Ha-Na Shim, Kevin T Hultgren, Suzana Gomes, Ani Solanki, Melody A Swartz, Jeffrey A Hubbell

“…Therefore, the rational design of immune modulators that can control the immune suppressive properties of TAMs and polarize them, as well as dendritic cells (DCs), toward a more proinflammatory phenotype is a principal objective in cancer immunotherapy.Methods Here, using a protein engineering approach to enhance cytokine residence in the tumor microenvironment, we examined combined stimulation of the myeloid compartment via tumor stroma-binding granulocyte–macrophage colony-stimulating factor (GM-CSF) to enhance responses in both DCs and T cells via stroma-binding interleukin-12 (IL-12). …”
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Adipocyte Atrophy Mimicking Signet Ring Cell Carcinoma of the Gallbladder by Benjamin van Haeringen, Leo Francis, Emily Olive, Daniel James

“…Compared to malignant signet ring cell carcinoma, benign signet ring cell change is more likely to retain normal lobulated architecture without mass formation, lack significant atypia, have myxoid stroma with a prominent capillary network, and show positive staining S100 protein with negative staining for cytokeratins and mucin. …”
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Penile Livedoid Vasculopathy: First Reported Case by Ahmad Hallak, William Bennett, Mohammed Adib Tanbir, Supriya R. Donthamsetty, Bethaney Vincent

“…Due to diagnostic uncertainty, a biopsy was performed which revealed hyaline thrombi within the lumens of small vessels within the upper to mid dermis, fibrinoid material in the walls of these blood vessels and within the perivascular stroma with overlying and adjacent epidermal spongiosis, and mild perivascular lymphocytic infiltrate with a few scattered neutrophils most consistent with livedoid vasculitis. …”
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Biliary Adenofibroma with Carcinoma In Situ: A Rare Case Report by N. Thao T. Nguyen, Theresa R. Harring, Laurie Holley, John A. Goss, Christine A. O’Mahony

“…This exophytic, multicystic, 6.5 × 5.0 cm mass was composed of complex tubulocystic structures lined by nonmucin-secreting, biliary epithelium embedded in fibrous stroma, consistent with biliary adenofibroma. This is the seventh case described in the literature. …”
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PIK3CA and p53 Mutations by Next Generation Sequencing in Lymphoepithelioma-Like Carcinoma of the Endometrium by Lucie Bienfait, Nicky D’Haene, Xavier Catteau, Jean-Christophe Noël

“…Lymphoepithelioma-like carcinoma of the endometrium is a very rare variant of endometrial carcinoma characterized by syncytial nests of pleomorphic epithelial cells and heavy infiltration of the stroma by lymphocytes (in particular CD8 cytotoxic T-lymphocytes) and plasma cells. …”
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Reporting a Rare Case of Pleomorphic Adenoma of the Breast by Tahere Khamechian, Javad Alizargar, Tahere Mazoochi

“…After an excisional biopsy, the pathologist found proliferation in epithelial and myoepithelial cells that had small and multiple nuclei, myxoid and chondroid stroma. Immunohistochemistry stain was positive for S-100 and patchy for GFAP in tumor cells and for SMA around the tubule-glandular and tumor cell aggregates and suggested PA of the breast. …”
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Diabetic Mastopathy: An Uncommon Complication of Diabetes Mellitus by R. X. Kirby, D. I. Mitchell, N. P. Williams, D. A. Cornwall, S. O. Cawich

“…Histopathologic evaluation revealed classic features of DMP: parenchymal fibrosis; keloid-like hyalinization of interlobular stroma; adipose tissue entrapment; lobular compression; dense chronic inflammatory cell infiltration; and lymphoid follicle formation. …”
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Otras masculinidades: Prácticas corporales y danza by Karla Jeanette Chaco\u0301n Reynosa, Raquel Herna\u0301ndez Go\u0301mez

“…En el análisis de la constitución de masculinidades no hegemónicas a partir de la danza escénica, ofrecemos tres itinerarios corporales que suponen un auténtico campo cultural en el cual, se alzan confrontaciones con los modelos tradicionales de masculinidad y emergen de ellas un despliegue de “otras prácticas”: precarias, débiles, inestables que (re) construyen lo masculino; Esta (re) construcción abona en el terreno performativo de la danza escénica, otrora considerado, como espacio “feminizado” para reconocerlo y resignificarlo como arena de transformación corporal y encarnación de otras prácticas masculinas: sus afectos, el desarrollo de la apreciación estética, el cuidado físico y la experiencia corporal.…”
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Epithelioid Hemangioendothelioma with WWTR1-CAMTA1 Fusion in the Parotid Gland Presenting as Bell’s Palsy by Landon J. Kunzelman, Shweta Agarwal, Nathan Boyd, Cory J. Broehm

“…Surgical resection showed a tumor comprised of atypical cells with occasional intracytoplasmic vacuoles in a fibromyxoid stroma. Immunohistochemical stains demonstrated the neoplastic cells expressed ERG, CD31, and CD34, confirming vascular differentiation. …”
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Targeted therapy for pancreatic ductal adenocarcinoma: Mechanisms and clinical study by Heng‐Chung Kung, Jun Yu

“…Contributing to the poor prognosis of PDAC is the lack of early detection, a complex network of signaling pathways and molecular mechanisms, a dense and desmoplastic stroma, and an immunosuppressive tumor microenvironment. …”
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Percorsi culturali e patrimonio religioso: Multi-dinamica di una categoria trasversale in un contesto turistico by Isabelle Brianso

“…Dal 1987, le tracce geografiche (strada, sentiero, percorso) del Medioevo sono state trasformate in itinerari culturali certificati dal Consiglio d'Europa. …”
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How does the wealth level of nations affect their COVID-19 vaccination plans? by Bilal Kargı, Mario Coccia, Bekir Cihan Uçkaç

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¿Autoempleados a falta de algo mejor? Crítica del discurso sobre la precariedad laboral desde la experiencia de un grupo de independientes by Ducange Medor Bertho

“…A partir de datos obtenidos de una investigación a base de entrevistas semiestructuradas y de observación con emprendedores o independientes de las tecnologías informáticas y del audiovisual, muestra la limitación de dicha noción para dar cuenta de la condición laboral de estos profesionales, toda vez que vinculan el trabajo con valores otros que los de estabilidad, seguridad y buena remuneración otrora puntales del empleo industrial fordista. Valores “posmaterialistas” como la horizontalidad, la camaradería, el share, la autonomía, la cooperación, la colaboración, etc., configuran la visión y la relación de estos individuos con el trabajo.…”
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Étudier les biens communs par les changements institutionnels : régimes de propriété autour des races animales face à l’innovation génomique by Julie Labatut, Franck Aggeri, Gilles Allaire

“…This article aims at using the analytical framework proposed by Schlager and Ostrom (1992) for a dynamic description of property rights in the management of common resources, here animal genetic resources. …”
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Los misterios y las andanzas de un trabajo de campo en la patagonia: el lugar de los 100 años de Comodoro Rivadavia by Elena Mariel Pacheco

“…El abordaje considera cómo a través de los “nuevos festejos” las localidades impactadas por el proceso de reestructuración del estado y la consecuente privatización de la petrolera estatal (Y.P.F.) buscan llenar los vacíos de simbolismo que otrora ocupaba el petróleo. El 23 de febrero del año 2001 “mi ciudad” (Comodoro Rivadavia, Chubut) festejó 100 años de su fundación y fui hacer trabajo de campo a efectos de completar un informe de investigación. …”
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