Advancing Anaesthetist Rostering Quality: A Practical Approach Toward Fairness and Efficiency by Norizal Abdullah, Masri Ayob, Meng Chun Lam, Nasser R. Sabar, Graham Kendall, Liu Chian Yong

“…We implemented the model at Hospital Canselor Tuanku Muhriz (HCTM), Malaysia, to handle various shift types across multiple locations for both monthly and weekly rosters. The proposed model optimises the roster by satisfying mandatory constraints first (such as legal requirements), and then minimising soft constraint violations, such as employee preferences, through iterative refinement. …”
Get full text

The effects of processing steps on avenanthramides, avenacosides and β-glucan content during the production of oat-based milk alternatives by Roisin McCarron, Lisa Methven, Sameer Khalil Ghawi, Stephanie Grahl, Ruan Elliott, Stella Lignou

“…With this information, future production may be optimised to better preserve potential health benefits of OMAs.…”
Get full text

Advances in chromosomal microarray analysis: Transforming neurology and neurosurgery by Wireko Andrew Awuah, Muhammad Hamza Shah, Vivek Sanker, Krishitha Meenu Mannan, Sruthi Ranganathan, Princess Afia Nkrumah-Boateng, Mabel Frimpong, Kwadwo Darko, Joecelyn Kirani Tan, Toufik Abdul-Rahman, Oday Atallah

“…Addressing these challenges will optimise CMA's impact, advancing personalised medicine and reshaping neurology. …”
Get full text

Narrowing the gap between machine learning scoring functions and free energy perturbation using augmented data by Ísak Valsson, Matthew T. Warren, Charlotte M. Deane, Aniket Magarkar, Garrett M. Morris, Philip C. Biggin

“…However, current models lack robust evaluation and fail on tasks encountered in (hit-to-) lead optimisation, such as ranking the binding affinity of a congeneric series of ligands, thereby limiting their application in drug discovery. …”
Get full text

Magnesium Oxide Nanoparticles Reinforced Electrospun Alginate-Based Nanofibrous Scaffolds with Improved Physical Properties by R. T. De Silva, M. M. M. G. P. G. Mantilaka, K. L. Goh, S. P. Ratnayake, G. A. J. Amaratunga, K. M. Nalin de Silva

“…These novel alginate-based/MgO scaffolds are economical and versatile and may be further optimised for use as extracellular matrix substitutes for repair and regeneration of tissues.…”
Get full text

Mesothelioma and Radical Surgery 2 (MARS 2): protocol for a multicentre randomised trial comparing (extended) pleurectomy decortication versus no (extended) pleurectomy decorticati... by Liz Darlison, John Edwards, Apostolos Nakas, Nick A Maskell, Wendy Underwood, Chris Rogers, Matthew Callister, David Waller, Richard Milton, Victoria Ashford-Turner, Paul Taylor, Claire Matthews, Victoria Hughes, Kelvin Lau, Alan Kirk, Robert C Rintoul, Elizabeth A Stokes, Kate Ashton, Daisy Elliott, Rosie Harris, Marie Kirwan, Juliette Novasio, Sara Waplington, Eric Lim, Holly Mckeon, Charlotte Jacobs, Laura White, Mary O’Brien, Judith Moore, Louise Li, Nicola Mills, Sanjay Popat, Suzanne Miller, Nadia Yousaf, D A Fennell, Clinton Ali, Andrea Bille, Liz Fuller, Andreea Ionescu, Manjusha Keni, Pek Koh, Talal Mansy, Dakshinamoorthy Muthukumar, Tony Pope, Amy Roy, Riyaz Shah, Jonathan Shamash, Zacharias Tasigiannopoulos, Sarah Treece, Katherine Joyce, Barbara Warnes, Athanasia Gravani, Rachel Brophy, Nicola Farrar, Jane Elliott, Philip Noyes, Louise Nelson, Sara Tenconi, Laura Socci, Hilary Wood, Helena Hanratty, Helena Stanley, Robert Rintoul, Amy Gladwell, Jenny Castedo, Amanda Stone, Charlotte Ingle, Hayley Hewer, Eleanor Aynsley, Andrea Watson, Alison Hassall, Masuma Begum, Christopher Worth, Ellie Piggott, Elizabeth Nadin, Yvonne Summers, Raffaele Califano, Laura Cove-Smith, Matt Evison, Maria Blinston, Amal Ismail, Rachel Chant, Asmita Desai, Ian Morgan, Victoria Lake, Nichola Harris, Simon Hodge, Nadza Tokaca, Adam Januszewski, Avani Athauda, Anisha Ramessur, Emily Grist, Niamh Colman, Michael Flynn, Joan Joyce, Sarah Vaughan, Maria Piga, Derya Sahin, Agnieszka Yongue, Emma Turay, Jaishree Bhosle, Rajiv Kumar, Charlotte Milner-Watts, Jessica Brown, David Walder, Alexandros Georgiou, Xiaorong Wu, Naila Kaudeer, Kroopa Joshi, Michael Davidson, Shelize Khakoo, Bee Ayite, Kathryn Priest, James Dobbyn, Vasanthi Prathapan, Deborah McCrimmon, Natalie Ash, Alison Norton, Bianca Peet, Libby Hennessy, Rosemary Johnson

“…The QuinteT Recruitment Intervention is integrated into the trial to optimise recruitment.Ethics and dissemination Research ethics approval was granted by London – Camberwell St. …”
Get full text

Postpartum haemorrhage following vaginal delivery: a comprehensive analysis and development of predictive models for aetiological subgroups in Chinese women by Hong Lin, Dandan Zhang, Jinke Li, Mengyuan Shao, Xiaoxue Wang, Xueting Chen, Yangzi Zhou, Zixuan Song

“…Our goal was to craft and validate predictive models to guide clinical decision-making and optimise resource allocation.Design A retrospective cohort study.Setting Shengjing Hospital of China Medical University, Liaoning Maternal and Child Health Hospital, and Shenyang Women’s and Children’s Hospital.Participants 29 842 women who underwent vaginal delivery were enrolled in the study across three hospitals from 2016 to 2022.Primary outcome measures PPH, categorised into uterine atony (UA), placental factors (PF), cervical trauma (CT), and coagulation abnormalities (CA) by aetiology.Results The logistic regression for overall PPH and UA-PPH showcased high discrimination (AUCs of 0.807 and 0.794, respectively), coupled with commendable calibration and DCA-assessed clinical utility, culminating in the development of a nomogram for risk prediction. …”
Get full text

Unveiling the UNESCO Biosphere Reserve of the Berlengas Archipelago in Portugal as a Hotspot of Fish Species Using eDNA Metabarcoding and the Collaboration of Fishing Crews by Marco Simões, Cátia Costa, Maria da Luz Calado, Nuno Vasco-Rodrigues, Maria Jorge Campos, Sérgio Miguel Leandro, Agostinho Antunes

“…Our study also highlighted eDNA’s role in monitoring fish species by detecting unexpected species for the region, such as Atlantic salmon (<i>Salmo salar</i>) and Atlantic cod (<i>Gadus morhua</i>), while cautioning against false positives like orange clownfish (<i>Amphiprion percula</i>) and blue tilapia (<i>Oreochromis aureus</i>). Future optimisation of our eDNA sampling methodology could better refine marine ecosystem dynamics around the UNESCO Biosphere Reserve of the Berlengas Archipelago, Portugal.…”
Get full text

Enhancing Thermal-Hydraulic Modelling in Dual Fluid Reactor Demonstrator: The Impact of Variable Turbulent Prandtl Number by Hisham Elgendy, Sławomir Kubacki, Konrad Czerski

“…Future work will apply this modelling approach to more complex geometries and flow scenarios to optimise thermal-hydraulic performance.…”
Get full text

Prospects and directions of diversification of oilseed group crops by Valentyna Gamayunova, Lyubov Khonenko, Vira Mykolaichuk, Anna Kuvshinova

“…According to the results, the use of an optimised nutrition system and a combined protection system increases the yield of sunflower seeds by 15%, the quality of oil by 10%, and the use of innovative elements for growing flax increases the oil content of seeds by 8%. …”
Get full text

Perspectives of healthcare stakeholders in Nigeria on the impact of COVID-19 on health services by Adeponle O. Adeoye, Yewande T. Nejo, Chinwe L. Ochu, Josephine Bayigga, Rodgers R. Ayebare, Adedayo O. Faneye, Charles O. Adewemimo, Oluwaseun Emmanuel Falayi, Adeniyi Francis Fagbamigbe, Prosper Okonkwo, Adewale Victor Opayele, Gloria Ogochukwu Nwiyi, Sunday Obiajunwa Eziechina, Ikemefule Rex Uzoma, Priscilla Ibekwe, Tamrat Shaweno, Nebiyu Dereje, Francis Kakooza, Mosoka Papa Fallah, Georgina Njideka Odaibo

“…Contribution: This article provides insights for public health policy and planning aimed at enhancing resilience and optimising service delivery during future health crises.…”
Get full text

A New Method for Designing Dense Skeleton Asphalt Mixture Based on Meso Parameter by Liwan Shi, Duanyi Wang, Junfeng Wang, Zhonghai Jiang, Hehao Liang, Xiao Qin

“…Furthermore, the capacity of the research has not risen to a level where a design method to guide the design and optimisation of the asphalt mixture gradation has been formulated. …”
Get full text

Robust proteome profiling of cysteine-reactive fragments using label-free chemoproteomics by George S. Biggs, Emma E. Cawood, Aini Vuorinen, William J. McCarthy, Harry Wilders, Ioannis G. Riziotis, Antonie J. van der Zouwen, Jonathan Pettinger, Luke Nightingale, Peiling Chen, Andrew J. Powell, David House, Simon J. Boulton, J. Mark Skehel, Katrin Rittinger, Jacob T. Bush

“…Screening libraries of reactive fragments by chemoproteomics offers a compelling approach to ligand discovery, however, optimising sample throughput, proteomic depth, and data reproducibility remains a key challenge. …”
Get full text

Exceeding expectations: A study on human resource management implementation in construction organisations by Munodani Chapano, Chux G. Iwu

“…Motivation of the study: The reason for this study was that a paucity of empirical research on the implementation of HRM practices makes it difficult to provide recommendations about HRM to optimise performance in construction organisations. …”
Get full text

Concepts and metrics of clinician attention: a scoping review protocol by Mark J Kissler, Katherine Kissler, Samuel C Porter, Angela Keniston, Katherine Jankousky, Marisha Burden

“…We anticipate results will identify diverse ways of conceptualising clinician attention and will provide a foundation for developing additional metrics and study methods to optimise attention in the clinical environment. We will disseminate results through journals and conferences and coordinate with colleagues doing work in adjacent fields.…”
Get full text

Development of Duloxetine Hydrochloride Tablets for Delayed and Complete Release Using Eudragit L 100 by M. Yasmin Begum, Ali Alqahtani, Mohammed Ghazwani, Noura Abdullah Alhamood, Umme Hani, Avanthi Jajala, Mohamed Rahamathulla

“…The formulation F8 was optimised with 5% and 15% increase in weight of seal coat and enteric coat with good dissolution profile. …”
Get full text

Bat Cave Vulnerability Index 3.0 (BCVI-S): An integrative and scalable tool to prioritise bat caves for conservation by Krizler C. Tanalgo, Alice Catherine Hughes

“…We calibrated the Bat Cave Vulnerability Index 3.0 (BCVI-S) and its indicators to optimise the scalability and applicability of the index in wider contexts by improving the calculations of Biotic Potential and the use of more standardised remotely sensed data to obtain Biotic Vulnerability based on landscape features. …”
Get full text

A review of electric vehicle technology: Architectures, battery technology and its management system, relevant standards, application of artificial intelligence, cyber security, an... by Vincent M. Macharia, Vijay K. Garg, Dinesh Kumar

“…This article comprehensively reviews the components and advances in the various technologies employed in electric vehicles to achieve efficiency in motion and optimise energy management in electric vehicles. This article gives an analysis of the current EV scenario globally. …”
Get full text

Effect of Boron Carbide Particles Addition on the Mechanical and Wear Behavior of Aluminium Alloy Composites by null Ravindra, M. Rajesh, K. Dilip Kumar, Mamunuri Sailender, G. Pathalinga Prasad, N. Nagaraj, Perumalla Janaki Ramulu

“…., two-stage stir casting to optimise wettability and distribution. Scanning electron microscopy (SEM) was utilised to examine the microstructure, and energy dispersive spectroscopy (EDS) was utilised to determine the elemental make-up. …”
Get full text

Board Gender Diversity and Risk Management in Corporate Financing: A Study on Debt Structure and Financial Decision-Making by Davood Askarany, Soleil Jafari, Azam Pouryousof, Sona Habibi, Hassan Yazdifar

“…It also offers practical implications for firms seeking to optimise their debt structures while maintaining sound risk management practices.…”
Get full text