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261
Targeting the 8-oxodG Base Excision Repair Pathway for Cancer Therapy
Published 2025-01-01“…Central to this pathway are enzymes like 8-oxoguanine glycosylase 1 (OGG1), which recognize and excise 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG) lesions, thereby initiating a series of repair processes that restore DNA integrity. …”
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262
Comparative Analysis of the Therapeutic Effects of MSCs From Umbilical Cord, Bone Marrow, and Adipose Tissue and Investigating the Impact of Oxidized RNA on Radiation-Induced Lung...
Published 2024-01-01“…The analysis of malondialdehyde (MDA) and 8-hydroyguanosine (8-OHG) content indicated that MSCs possess reparative properties against radiation-induced oxidative damage in lung tissue. …”
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263
Clinical Role of Epigenetics and Network Analysis in Eye Diseases: A Translational Science Review
Published 2019-01-01“…Hypermethylation in TGM-2 and hypomethylation in MMP-2/CD24 promoter genes may play a crucial role in pterygium development; hypermethylation in regulatory regions of GSTP1 and OGG1 genes appear to be diagnostic biomarkers of cataract; hypomethylation of TGF-β1 promoter may trigger glaucoma onset; hypermethylation of the LOXL1 gene might be associated with pseudoexfoliation syndrome. …”
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264
Case report: an unusual long-term evolution of a diffuse midline glioma, H3K27 altered
Published 2025-02-01“…Interestingly, MR imaging conducted for migraine diagnosis 6 years ago in retrospect already showed a small, nodular T2w hyperintense lesion in the right thalamus.ConclusionDespite a more precise, molecularly driven classification of pediatric HGG (high-grade glioma) in the 5th edition of the WHO classification of CNS tumors, many genetic factors influencing the biological tumor development as well as the precise molecular evolution of tumors remain unclear. …”
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265
European standard clinical practice recommendations for paediatric high-grade gliomas
Published 2025-06-01“…This guideline was written by members of the SIOPE HGG Working Group as part of the European Standard Clinical Practice (ESCP) Project. …”
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266
Kemik Yaşı ve Maturasyon Tespiti
Published 2020-04-01“…Radiusta epifiz ve diafiz kaynaşması olmuştur (Şekil1)Hagg ve Taranger, yaptıkları çalışmalarda el-bilek radyografilerini kullanarak orta parmak orta falanksının (MP3) olgunluk belirteçleriyle maturasyon safhalarını geliştirmeye çalışmışlardır.11,12 Yöntemde temel olarak orta parmaktaki epifiz diafiz bölgesinde olan gelişimsel değişiklikler 5 aşamada incelenmiştir.12 Bu aşamalar;1. …”
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267
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268
Physics case for an e+e− collider at 500 GeV and above
Published 2024-01-01“…Some highlights of the physics case for running an e+e− collider at 500 GeV and above are discussed with a particular emphasis on the experimental access to the Higgs potential via di-Higgs and (at sufficiently high energy) triple Higgs production. …”
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269
Classifying the CP properties of the ggH coupling in H + 2j production
Published 2025-01-01“…The Higgs-gluon interaction is crucial for LHC phenomenology. …”
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270
Standard Model Effective Potential from Trace Anomalies
Published 2018-01-01“…We discuss a particular realization of this potential in connection with the Higgs boson mass and Higgs boson effective couplings to two photons and two gluons. …”
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271
Dynamical Electroweak Symmetry Breaking with a Heavy Fermion in Light of Recent LHC Results
Published 2013-01-01“…The recent announcement of a discovery of a possible Higgs-like particle—its spin and parity are yet to be determined—at the LHC with a mass of 126 GeV necessitates a fresh look at the nature of the electroweak symmetry breaking, in particular if this newly-discovered particle will turn out to have the quantum numbers of a Standard Model Higgs boson. …”
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272
Gauge-Singlet Vector-Like Fermion Dark Matter, LHC Diphoton Rate, and Direct Detection
Published 2017-01-01“…We study a gauge-singlet vector-like fermion hidden sector dark matter model, in which the communication between the dark matter and the visible standard model sector is via the Higgs-portal scalar-Higgs mixing and also via a hidden sector scalar with loop-level couplings to two gluons and also to two hypercharge gauge bosons induced by a vector-like quark. …”
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273
Collider tests of nanohertz gravitational waves
Published 2024-01-01“…We present an MeV-scale first-order phase transition from a minimal dark sector to explain the gravitational waves, with a focus on the collider tests via the Higgs portal interaction. We demonstrate that to explain the observed gravitational waves, the Higgs portal coupling should be so sizable that it can be probed through Higgs invisible decay at the LHC and future colliders such as HL-LHC, CEPC, ILC, and FCC-ee. …”
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274
Truth, beauty, and goodness in grand unification: A machine learning approach
Published 2025-01-01“…There are two well-known approaches to address this issue: one involves introducing a 45-representation Higgs field, while the other employs a higher-dimensional operator involving the 24-representation GUT Higgs field. …”
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275
Symmetry breaking via internal geometry
Published 2005-01-01“…Gauge theories commonly employ complex vector-valued fields to reduce symmetry groups through the Higgs mechanism of spontaneous symmetry breaking. …”
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276
Application of Particle Transformer to quark flavor tagging in the ILC project
Published 2024-01-01“…International Linear Collider (ILC) is a next-generation e+e− linear collider to explore Beyond-Standard-Models by precise measurements of Higgs bosons. Jet flavor tagging plays a vital role in the ILC project by identification of H → bb¯, cc¯, gg, ss¯ to measure Higgs coupling constants and of HH → bb¯bb¯ and bb¯WW which are the main channels to measure the Higgs self-coupling constant. …”
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277
$$(g-2)_{e,\mu }$$ ( g - 2 ) e , μ and lepton flavor violating decays in a left-right model
Published 2024-12-01“…The results are used to discuss these decays as new physics signals in a minimal left-right symmetric model containing only one bidoublet Higgs and a $$SU(2)_R$$ S U ( 2 ) R Higgs doublet accommodating data of neutrino oscillations and $$(g-2)_{\mu }$$ ( g - 2 ) μ . …”
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278
QCD axion strings or seeds?
Published 2025-01-01“…We consider the case of the pure SM Higgs potential as well as a simple scenario with a first order EW phase transition. …”
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279
Towards an update of the ILD ZHH analysis
Published 2024-01-01“…The double Higgs-strahlungs process e+e− → ZHH allows to access the Higgs self-coupling at center-of-mass energies above 450 GeV. …”
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280
Inflation models with Peccei–Quinn symmetry and axion kinetic misalignment
Published 2024-12-01“…We introduce a PQ complex scalar field and an extra Higgs doublet, which are conformally coupled to gravity, and three right-handed neutrinos for the seesaw mechanism. …”
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