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18141
Collagen deposition in lung parenchyma driven by depletion of interstitial Lyve-1+ macrophages prevents cigarette smoke-induced emphysema and loss of airway function
Published 2025-01-01“…A decrease in MMP-9 gene expression and proteolytic activity together with an increase in Col1a1, Timp-3 and Lox expression accompanied the collagen alterations. Next, we investigated the effect of the collagen remodeling on the pathophysiology of COPD and airway function in mice lacking Lyve-1+ macrophages exposed chronically to cigarette smoke (CS), a well-established animal model of COPD. …”
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18142
Deteksi Persamaan Pola Gerakan pada Koreografi Tari Bali
Published 2023-10-01“…This research was conducted under the framework of Project COMPUDANCE (Computerization of Dances), the goal of this project is to create a new dance by identifiying the characteristics of each Balinese dance creator. …”
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18143
Cell-Free Strategies for Repair and Regeneration of Meniscus Injuries through the Recruitment of Endogenous Stem/Progenitor Cells
Published 2018-01-01“…This review first compares cell-based to cell-free techniques. Next, it summarizes potential sources for endogenous stem/progenitor cells. …”
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18144
Whole genomic analysis uncovers high genetic diversity of rifampicin-resistant Mycobacterium tuberculosis strains in Botswana
Published 2025-02-01“…Sequencing was done on Illumina NextSeq2000. TBProfiler software was used to identify known M. tb lineages and drug resistance profiles. …”
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18145
Comprehensive genomic surveillance reveals transmission profiles of extensively drug-resistant tuberculosis cases in Pará, Brazil
Published 2025-01-01“…We recommend greater attention from the regional public health authorities to detect and track resistance to new drugs, especially in areas with pre-XDR and XDR cases. …”
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18146
Les fours « à pain » dans les Gaules et les Germanies (ve s. av. J.-C.-ve s. apr. J.-C.), un regard technique
Published 2021-12-01“…In general, the interpretation of a heating structure as a bread oven necessitates an absence of nearly any other type of evidence of use, i.e. traces linked to the working of metals or glass or of hearth vitrification. …”
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18147
Editorial
Published 2018-12-01“… Among the many headlines that followed the 2018 midterm elections in the United States, one stood out as very good news for political representation: the election of Alexandria Ocasio-Cortez. …”
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18148
A novel oncolytic Vaccinia virus armed with IL-12 augments antitumor immune responses leading to durable regression in murine models of lung cancer
Published 2025-01-01“…Here, we investigated the use of VVL-m12, a next-generation, genetically modified, interleukin-12 (IL-12)-armed VV, as a new therapeutic strategy to treat murine models of lung cancer and as a mechanism of increasing lung cancer sensitivity to antibody against programmed cell death protein 1 (α-PD1) therapy. …”
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18149
AutoLDP: An accurate and efficient artificial intelligence-based tool for automatic labeling of digital pathology
Published 2025-03-01“…The method includes four steps: identifying text position using the CRAFT model, recognizing text content using the ParSeq model, identifying slice type using the ConvNext classifier, and combining relevant information to generate a new name. …”
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18150
Motor transport development in Klaipėda district in 1900-1939
Published 2009-12-01“…In Klaipėda district, the most widespread were German and American cars, popular makes being Opel, Ford, Chevrolet, and Mercedes Benz. From the 4th decade of the XX century, passenger motor transport started to develop rapidly in Klaipėda district. …”
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18151
动物园禽源奇异变形杆菌对第三代头孢菌素的耐药分子机制
Published 2024-11-01“…结果发现:共有6株受试菌对第三代头孢菌素耐药,除1株(6D)携带超广谱<italic>β</italic>-内酰胺酶<italic>bla</italic><sub>CTX-M-14</sub>和1株(106A)携带AmpC酶<italic>bla</italic><sub>ACT-16</sub>外,其余4株经PFGE检测证实为同一克隆型,且细菌体内双组分信号转导系统CpxAR、BaeSR和EnvZ/OmpR的表达量显著高于敏感菌,主要通过抑制耐药菌细胞膜上OmpC和OmpF的表达减少药物吸收,同时促进OmpW表达加速药物外排,从而减少菌体内药物浓度,进而导致其对第三代头孢菌素类耐药。…”
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18152
First Detection and Genomic Characterization of Linezolid-Resistant <i>Enterococcus faecalis</i> Clinical Isolates in Bulgaria
Published 2025-01-01“…Efs966-bg (MIC = 8 mg/L) carried a plasmid-located <i>optrA</i> determinant surrounded by <i>fexA</i> and <i>ermA</i>. No mutations in the genes encoding for ribosomal proteins L3, L4, and L22 were detected. …”
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18153
Sex-related Anthropometrics in a Lower-Body Mobility Assessment Among Professional Soccer Athletes
Published 2022-04-01“…A two-tailed t-test was used to compare YBT between sexes. Chi-square was used for sex comparisons of FMS™ scores. …”
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18154
DDX50 cooperates with STAU1 to effect stabilization of pro-differentiation RNAs
Published 2025-01-01“…Here, we demonstrate that glucose binding is a general capacity of DExD/H-box RNA helicases, including DDX50, which was found to be essential for the differentiation of diverse cell types. …”
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18155
Blade pitching in vertical axis wind turbines: A double multiple stream tube theoretical approach to performance enhancement
Published 2025-02-01“…A peak average coefficient of performance (Cp) of 0.568 was achieved at TSR = 5 using pitching Model 1 with a maximum angle of attack of 8.5°, compared to a Cp of 0.48 for the fixed blade configuration, near to Betz's limit (Cp = 0.593). The findings confirm that integrating variable blade pitching would substantially improve VAWT performance and offer a clear direction for revolutionary future wind turbine aerodynamic design enhancements.…”
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18156
A Feasibility Analysis of Wind Energy Potential and Seasonal Forecasting Trends in Thatta District: A Project to Combat the Energy Crisis in Pakistan
Published 2025-01-01“…Wind shear at different heights was determined using the power law, and wind potential maps were generated using GIS interpolation techniques. Betz’s law was employed to assess wind turbine power density. …”
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18157
Short Bowel Patients Treated for Two Years with Glucagon-Like Peptide 2: Effects on Intestinal Morphology and Absorption, Renal Function, Bone and Body Composition, and Muscle Func...
Published 2009-01-01“…In addition, mucosal morphometrics, renal function (by creatinine clearance), body composition and bone mineral density (by DEXA), biochemical markers of bone turnover (by s-CTX and osteocalcin, PTH and vitamin D), and muscle function (NMR, lungfunction, exercise test) were measured. …”
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18158
The impact of glucocorticoid receptor transactivation on context-dependent cell migration dynamics
Published 2025-02-01“…RNA sequencing revealed dex’s impact on cell adhesion and extracellular matrix signalling in TN cells and on DNA replication in ER + cells. …”
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18159
Elements of legislation /
Published 2013Table of Contents: “…The supremacy problem -- The quest to intellectualize statute law -- Legislatures and intentions -- Fidelity to text -- Purposivism, past and present.…”
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18160
Isolation, identification and characteristics of Aeromonas sobria from diseased rainbow trout (Oncorhynchus mykiss)
Published 2025-01-01“…In addition, eight virulence genes were screened from strain As012, including Act, Aer, AexT4, Alt, ahyB, ascV, Nuc and Hly. The strain As012 can grow in the environment with pH 1–11, temperature 8–43°C and NaCl concentration 0–8%. …”
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