Addressing Critical Mistakes in Administering Intravenous Medications at Omdurman Military Hospital, Khartoum, Sudan by Ahmed WAM, Abdelrahman AEHE, Mohamed AA, Mohammed IO, Mustafa AMA, Ahmed ZEE, Mohamed MMT, Alghamdi FAA, Elbashir AEE, Alkubati S, Al-Sowaidi A, Dinar NMAA, Obadi AA, Saleh KA

“…Additionally, 83.3% of nurses did not label the unused portion of a drug intended for the next dose.Conclusion: This study identifies a total of 11 different types of errors in IV drug preparation and administration, some of which are associated with the hospital’s work environment. …”
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Perancangan Perangkat Audit Internal untuk Sistem Keamanan Informasi pada Organisasi XYZ by Arif Rahman Hakim, Rizky Aditya Pratama Wijaya

“…The results of implementation trials, assessment, and finalization of our audit tool shows that our audit tool has been consistent with the needs of XYZ organization. …”
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What all physicians should know about women’s health: a Delphi study by Susanna Price, Eva Gerdts, Julien Mazières, Alexandra Kautzky-Willer, Fedde Scheele, Chiara Benedetto, Kerry Wilbur, Gertraud Stadler, Marieke Wermer, Jeanine Roeters van Lennep, Merel H de Heer-Koster, Vesna Bjegović-Mikanović, Indre Banaitytė-Baleišienė, Mary Perdiou, Alyson McGregor, Connie Newman, Simona Stankevičiūtė, Iris E Sommer, Florence Thibaut, Karine van 't Land

“…Objectives Over the past few decades, knowledge of women’s health regarding sex and gender differences in health has increased but transfer of these new insights into medical education and clinical practice is lagging, resulting in substandard care for women compared with men. …”
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SIMULASI PENCAHAYAAN ALAMI SIANG HARI TERHADAP DESAIN FASAD (STUDI KASUS: GEDUNG LABORATORIUM TEKNIK ELEKTRO UNIVERSITAS MALIKUSSALEH) by Leo Sani Muslim Pinem, Atthaillah Atthaillah, Effan Fahrizal, Eri Saputra, Badriana Badriana

“…This research investigated the Laboratory of Electrical Engineering building of Universitas Malikussaleh, Lhokseumawe, Indonesia. Next, this study adopted Climate Based Daylight Modeling (CBDM) utilizing Useful Daylight Illuminance (UDI) metric as the criteria for the daylight performance.   …”
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Trial protocol of an open-label pilot study of oral naltrexone–bupropion combination pharmacotherapy for the treatment of methamphetamine use disorder (the NABU trial) by Jonathan Brett, Paul S Haber, Nicholas Lintzeris, Didier Jutras-Aswad, Nadine Ezard, Brendan Clifford, Krista J Siefried, Adrian John Dunlop, Liam Acheson, Carl Moller, Michael Christmass, Kirsten Morley, Steven Shoptaw, Madhukar H Trivedi

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Comprehensive analysis of antimicrobial resistance dynamics among broiler and duck intensive production systems by Zsombor Szoke, Peter Fauszt, Maja Mikolas, Peter David, Emese Szilagyi-Tolnai, Georgina Pesti-Asboth, Judit Rita Homoki, Ildiko Kovacs-Forgacs, Ferenc Gal, Laszlo Stundl, Levente Czegledi, Aniko Stagel, Sandor Biro, Judit Remenyik, Melinda Paholcsek

“…A total of 96 pooled samples were collected: 50 from broiler farms (26 biological, 24 environmental) and 46 from duck farms (24 biological, 22 environmental). Using next-generation shotgun sequencing, 3,665 distinct AMR types were identified: 1,918 in broilers and 1,747 in ducks. …”
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CD94-driven in vitro expansion of highly functional adaptive NKG2C+ NKG2A- CD57+ NK cells from CMV+ healthy donors by Chiara Giordano, Simona Carlomagno, Simona Carlomagno, Michela Falco, Claudia Cantoni, Claudia Cantoni, Massimo Vitale, Ignazio Caruana, Johannes Dirks, Alberto Serio, Letizia Muccio, Giulia Bartalucci, Alessandra Bo, Franco Locatelli, Franco Locatelli, Cristina Bottino, Cristina Bottino, Simona Sivori, Simona Sivori, Mariella Della Chiesa, Mariella Della Chiesa

“…In light of these features, adaptive NK cells represent suitable candidate to design next-generation therapies, based on their enhanced effector function which could be further boosted by Chimeric Antigen Receptors-engineering, or the combination with cell engagers. …”
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Long-term outcomes combined minimally invasive laser surgical technique for local rhegmatogenous retinal detachment by A.V. Doga, D.O. Shkvorchenko, L.A. Kryl, M.R. Taevere, D.A. Buryakov

“…Recurrent RRD occurred in 3 patients (7.9%) because of new inferior retinal breaks. In four patients (10.5%), postoperative wide-field OCT of the area of the initial retinal tear performed after reattachment revealed additional pathological vitreoretinal adhesions in the adjacent areas (that were not identified preoperatively). …”
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Optimising Access Surgery in Senior Haemodialysis Patients (OASIS): study protocol for a multicentre randomised controlled trial by Patrick WHE Vriens, Edith M Willigendael, Maarten A Lijkwan, Friedo W Dekker, Chava L Ramspek, Michiel W de Haan, Çaĝdaş Ünlü, Boudewijn DC Heggen, Koen E A van der Bogt, Marc H Hemmelder, Mickaël J C Hiligsmann, Magda M van Loon, Joris I Rotmans, Jan H M Tordoir, Geert Willem H Schurink, Maarten G J Snoeijs, Marijke J Molegraaf, Philippe WM Cuypers, Denise Nio, Cora H Arts, Jacobien C Verhave, Goos D Laverman, Aron S Bode, Marcel C Weijmer, Bas Govaert, Aaltje Y Adema, Gijs MJM Welten, Michel MPJ Reijnen, Marc JH Groeneveld, Hans S Brink, Jeroen B van der Net, Arno Kuijper, Hilde PE Peters, Roos C van Nieuwenhuizen, Rombout R Kruse, Yvonne C Schrama, Karina A de Groot, Karima Farhat

“…Patients aged 70 years or older who are expected to initiate haemodialysis treatment in the next 6 months or who have started haemodialysis urgently with a catheter will be enrolled. …”
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Prevalence and molecular characterization of human bocavirus-1 in children and adults with influenza-like illness from Kunming, Southwest China by Yanhong Sun, Lili Jiang, Yaoyao Chen, Zhaosheng Liu, Meiling Zhang, Xiaonan Zhao, Xiaoyu Han, Lifen Zhang, Xiaoqing Fu, Jienan Zhou

“…Each specimen was tested for 18 respiratory viruses, and the positive rates of HBoV-1 across different age groups were analyzed. Amplification of the near-complete HBoV genome was achieved through three overlapping fragments, followed by next-generation sequencing (NGS) and phylogenetic analysis. …”
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In situ training of an in-sensor artificial neural network based on ferroelectric photosensors by Haipeng Lin, Jiali Ou, Zhen Fan, Xiaobing Yan, Wenjie Hu, Boyuan Cui, Jikang Xu, Wenjie Li, Zhiwei Chen, Biao Yang, Kun Liu, Linyuan Mo, Meixia Li, Xubing Lu, Guofu Zhou, Xingsen Gao, Jun-Ming Liu

“…Abstract In-sensor computing has emerged as an ultrafast and low-power technique for next-generation machine vision. However, in situ training of in-sensor computing systems remains challenging due to the demands for both high-performance devices and efficient programming schemes. …”
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Neuropilin1-dependent paracrine signaling of cancer cells mediated by miRNA exosomal cargo by Claudia Palazzo, Roberta Mastrantonio, Noemi Gioelli, Erika Testa, Francesco Recco, Donatella Lucchetti, Giulia Villari, Alessio D’Alessio, Alessandro Sgambato, Flavio Mignone, Guido Serini, Maria Teresa Viscomi, Luca Tamagnone

“…The micro-RNA profile carried by exosomes was investigated by Next Generation Sequencing. miRNA-Scope in situ hybridization was used to assess the transfer of miRNA exosome cargo to target cells, and immunofluorescence analysis revealed expression regulation of targeted proteins. miRNA activity was blocked by the use of specific antago-miRs. …”
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Diagnosis and Treatment of Patients with Autoimmune Hepatitis (Experts’ Agreement) by Yu. G. Sandler, E. V. Vinnitskaya, K. L. Raikhelson, K. V. Ivashkin, S. N. Batskikh, E. N. Aleksandrova, D. T. Abdurakhmanov, D. I. Abdulganieva, I. G. Bakulin, A. O. Bueverov, S. L. Vorobyev, O. A. Gerasimova, A. I. Dolgushina, M. S. Zhuravleva, L. Yu. Ilchenko, V. E. Karev, N. V. Korochanskaya, I. L. Kliaritskaia, N. S. Karnaukhov, S. V. Lapin, M. A. Livzan, M. V. Maevskaya, N. V. Marchenko, T. P. Nekrasova, I. G. Nikitin, A. A. Novikov, R. G. Saifutdinov, E. V. Skazyvaeva, V. E. Syutkin, M. K. Prashnova, T. Yu. Khaymenova, S. G. Khomerik

“…Updating approaches to the management of patients with AIH necessitated next systematization for use in clinical practice. …”
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Telomere Length Is Associated With Adverse Atrial Remodeling in Patients With Atrial Fibrillation by Kabita Pradhan, Balram Neupane, Paul Niehues, Martin Kirschner, Fabian Beier, Chao‐Chung Kuo, Erika Anneliese Hilbold, Christian Bär, Oana‐Maria Thoma, Maximilian Waldner, Margherita Vieri, Tim H. Brümmendorf, Vithurithra Tharmapalan, Wolfgang Wagner, Michael Kleines, Mahdi Emrani, Matthias Daniel Zink, Andreas Napp, Nikolaus Marx, Michael Gramlich

“…Clonal hematopoiesis of indeterminate potential was assessed by next generation sequencing. Telomerase reverse transcriptase knockout (Tert−/−) and telomerase RNA component knockout (Terc−/−) mice were used to investigate the mechanistic impact of telomere shortening on atrial remodeling. …”
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Clinical utility and predictive value of cerebrospinal fluid cell-free DNA profiling in non-small cell lung cancer patients with leptomeningeal metastasis by Sheng-Kai Liang, Wei-Yu Liao, Jin-Yuan Shih, Chia-Lin Hsu, Ching-Yao Yang, Shang-Gin Wu, Yen-Ting Lin, Yueh-Feng Wen, Lun-Che Chen, Yen-Fu Chen, Ya-Fang Chen, Yen-Heng Lin, Chong-Jen Yu

“…Cerebrospinal fluid (CSF) cell-free DNA (cfDNA) analysis using next-generation sequencing (NGS) offers insights into resistance mechanisms and potential treatment strategies. …”
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Low & Anaplastic Grade Glioma Umbrella Study of MOlecular Guided TherapieS (LUMOS-2): study protocol for a phase 2, prospective, multicentre, open-label, multiarm, biomarker-direct... by Marshall Pitz, Eng-Siew Koh, Elizabeth H Barnes, Lucille Sebastian, Mandy L Ballinger, David M Thomas, Christopher O'Callaghan, John Simes, Hui K Gan, Sonia Yip, Hao-Wen Sim, Desma Spyridopoulos, Richard De Abreu Lourenco, Cynthia Hawkins, Kristen McParland, Benjamin Kong, Subotheni Thavaneswaran, Patrick J Wheeler

“…Investigational treatment will be assigned based on molecular profiling of contemporaneous tissue obtained at disease relapse using next-generation sequencing. LUMOS-2 will begin with three therapeutic treatment arms: paxalisib, cadonilimab and selinexor. …”
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Discovery of phloridzin as a new antagonist for Di(2-ethylhexyl) phthalate-induced male reproductive toxicity based on the adverse outcome pathway network and drug-target gene set enrichment analysis by Huan Gao, Xue Zhang, Ziqi Liu, Xiaoge Yang, Yajie Li, Mengxing Cui, Han Wang, Xiaoyu Chen, Weiying Zhang, Zhihan Liu, Yongjiang Yu, Liping Chen, Daochuan Li, Yongmei Xiao, Wen Chen, Qing Wang

“…In this study, 552 genes related to MRT induced by DEHP/MEHP were screened out from the Comparative Toxicogenomics Database (CTD) and DisGeNET database. Next, we developed a global adverse outcome pathway (AOP) network based on the existed AOP-wiki. …”
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Arginase-1-specific T cells target and modulate tumor-associated macrophages by Mads Hald Andersen, Inés Lecoq, Ayako Wakatsuki Pedersen, Evelina Martinenaite, Shamaila Munir Ahmad, Maria Perez-Penco, Lucia Lara de la Torre, Marion Chapellier, Lars Rønn Olsen, Mia Aaboe-Jørgensen, Hannah Jorinde Glöckner, Anne Mette Askehøj Rømer

“…Furthermore, murine CD4+Arg1-specific T cells were able to target TAMs and effectively reprogram their phenotype ex vivo by secreting IL2 and IFNγ. Next, we established that human Arg1+TAMs present Arg1-derived peptides and are directly recognized by proinflammatory CD4+Arg1-specific T cell clones. …”
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Noel Hernández Rodríguez, scalpel in hand plastic surgeon by Tatiana Hernández González, Yaneisy Valdés Gutierrez, Yurisbel Tomás Solenzal Alvarez

“…Hilario Hernández Rodríguez, "Noe", as he was affectionately called by his residents and by all those who knew him as Noel, passed away on December 24, 2023, leaving an empty physical space next to family, friends, co-workers, patients and those who were his students for many years.…”
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Fully automated extraction of high-quality total nucleic acids from FFPE specimens for comprehensive genomic profiling of solid tumors by Kristopher Amirault, Michael Collins, Luca Beker, Brandon Mills, Martina Werner, Jonathan Andreas, Daniel Hartman, Jordan Dargert, Vanessa Process, Sean Cederlund, Thuy Dao, Linnea Menin, Molly Ferrara, Andrew Briggs, Joshua Shreve, Daniel Metzger, Angela Stout, Erin Deblasi, Jie An, Taylor Jensen, Shengle Zhang, Vinesh Rana, Bryn Burlingame, Ulrich Thomann, Durga Prasad Dash, Sha Liao, Jeffrey M. Conroy, Eugenio Daviso

“…By identifying actionable mutations through next-generation sequencing of solid tumors CGP enables targeted therapy decisions. …”
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