Report on the Dutch Consensus Development Meeting for Implementation and Further Development of Population Screening for Colorectal Cancer Based on FOBT by M. de Visser, M. van Ballegooijen, S. M. Bloemers, S. J. H. van Deventer, J. B. M. J. Jansen, J. Jespersen, C. Kluft, G. A. Meijer, J. Stoker, G. A. de Valk, M. F. Verweij, F. A. Vlems

“…A list of organisational actions to be taken was established. Research that is needed before the actual national launch of the screening within 2–3 years has been defined. …”
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Rumen DNA virome and its relationship with feed efficiency in dairy cows by Xiaohan Liu, Yifan Tang, Hongyi Chen, Jian-Xin Liu, Hui-Zeng Sun

“…In this study, rumen fluid from 30 Chinese Holstein dairy cows was analyzed using next-generation sequencing (NGS) and High-Fidelity (HiFi) sequencing to elucidate the rumen DNA virome profile and uncover potential viral mechanisms influencing FE. …”
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Rare Somatic MEN1 Gene Pathogenic Variant in a Patient Affected by Atypical Parathyroid Adenoma by Luigia Cinque, Flavia Pugliese, Celeste Clemente, Stefano Castellana, Maria Pia Leone, Danilo de Martino, Teresa Balsamo, Claudia Battista, Tommaso Biagini, Paolo Graziano, Marco Castori, Alfredo Scillitani, Vito Guarnieri

“…We suggest that MEN1 gene could be an underestimate genetic determinant of these rare histological entities, and we highlight the utility of a complete genetic screening protocol, by the use of next-generation sequencing technology in such undetermined clinical cases with no frank clinical presentation.…”
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Effect of stoking density on the productivity parameters of young-of-the-year tench (Tinca tinca Linnaeus, 1758) grown in recirculation aquaculture system conditions by R. Konopelsky, H. Kurinenko, I. Hrystyniak, M. Korilyak

“…/m3, with the repeatability for two years (Experiment I – 2021, Experiment II – 2022). Over the next 94 days, at stocking densities of 15 and 20 thousand ind.…”
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A proposal of visual assessment of serotonergic deficits in parkinsonian syndromes: An 123I-FP-CIT SPECT study by Tomoko Totsune, Toru Baba, Yoko Sugimura, Hideki Oizumi, Hiroyasu Tanaka, Toshiaki Takahashi, Masaru Yoshioka, Ken-ichi Nagamatsu, Atsushi Takeda

“…First, we graded 123I-FP-CIT uptake in the midbrain and pons with a 4-degree scale and analyzed the interrater agreement of our grading method. Next, we compared the visual grading data of the PD (n = 59) and PS (n = 11) groups and analyzed the diagnostic utility of the qualitative visual assessment method. …”
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Associations between contextual and compositional characteristics of early childcare facilities with health, health behaviours and well-being among young children aged 0 to 6 years... by Jennifer Hilger-Kolb, Sven Schneider, Raphael Herr, Nina Osenbruegge, Stephanie Hoffmann, Max Herke, Claudia Pischke, Leonie Sundmacher, Katharina Diehl

“…At the meso-level (institutional-level), early childcare facilities (eg, kindergartens, preschools) are the most important agent of socialisation next to families in young children aged 06 years. …”
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Mutation in the COL2A1 gene is associated with acetabular dysplasia by Miaomiao Xin, Xin Guan, Xin Guan, Jiangfei Yang, Yi Li, Zhentao Man, Hongsheng Sun, Min Fu

“…Clinical whole-exome sequencing (WES) using next-generation sequencing (NGS) was conducted to identify potential mutation sites, which were then validated through Sanger sequencing. …”
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Integrated multidisciplinary analysis of mobile digital radiographic acquisitions of the mummies of the hermits from the Sanctuary of Madonna della Corona (Trentino-Alto Adige, Ita... by Omar Larentis, Omar Larentis, Omar Larentis, Ilaria Gorini, Michele Campus, Marta Lorenzetti, Giancarlo Mansueto, Susanna Bortolotto, Emanuele Zappa, Andrea Gregorini, Laura Rampazzi, Stefano Vanin, Giuseppina Carta, Alberto Carli, Lara Simonaitis, Lisa De Luca, Enrica Tonina

“…This article highlights next-generation X-ray technology utility, potential, and limitations in investigating clothing fabrics, restoration history, taphonomy, entomology, anthropology, and paleopathology. …”
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Optomechanical Gyroscope Based on Micro-Hemispherical Shell and Optical Ring Resonators by Jamal N. A. Hassan, Wenyi Huang, Maoyuan Wang, Senyu Zhang, Guangjun Wen, Yongjun Huang

“…Overall, the gyroscope design utilizes principles of both mechanical resonators and integrated photonics to address challenges in on-chip light coupling and angular velocity detection for next-generation optomechanical inertial sensors. …”
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Humanities education reform exploration and practice under outcomes-based education (OBE) by P. Yang

“…Spady, and has been widely valued and applied in a rapid speed. During the next 10 years, OBE has formed a relatively complete theoretical system and became the mainstream ideas of national education reform in the United States, Britain, Canada and other counties. …”
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Machine learning-based identification of proteomic markers in colorectal cancer using UK Biobank data by Swarnima Kollampallath Radhakrishnan, Dipanwita Nath, Dominic Russ, Dominic Russ, Dominic Russ, Laura Bravo Merodio, Laura Bravo Merodio, Laura Bravo Merodio, Priyani Lad, Folakemi Kola Daisi, Animesh Acharjee, Animesh Acharjee, Animesh Acharjee

“…Incidence and mortality are predicted to rise globally during the next several decades. When detected early, colorectal cancer is treatable with surgery and medications. …”
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Serum calcium and its relationship with immunoglobulin G (IgG) levels in prepartum buffaloes from the Venezuelan humid tropics by Juan Pablo Uzcátegui-Varela, Anacelmira Urbina Andueza, Janeth Caamaño Carrero

“…The sampling consisted of collecting 6 milliliters (mL) of blood by jugular venipuncture in tubes without anticoagulant; then, the serum was separated by centrifugation at 3,300 r.p.m. for 20 minutes at 25 °C using a BOECO®-Germany centrifuge. Next, 1 mL of serum was taken to determine the serological parameters under study. …”
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Susceptibility to Ventricular Arrhythmias Resulting from Mutations in FKBP1B, PXDNL, and SCN9A Evaluated in hiPSC Cardiomyocytes by Hector Barajas-Martinez, Maya Smith, Dan Hu, Robert J. Goodrow, Colleen Puleo, Can Hasdemir, Charles Antzelevitch, Ryan Pfeiffer, Jacqueline A. Treat, Jonathan M. Cordeiro

“…Genetic analysis using next-generation DNA sequencing revealed heterozygous mutations in SCN9A, PXDNL, and FKBP1B in the proband. …”
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Repurposing of propane oxidative-dehydrogenation catalysts to deoxygenation of vegetable oils for green diesel production by S. Lucantonio, G. Di Vito Nolfi, C. Courson, K. Gallucci, A. Di Giuliano, L. Rossi

“…The market for diesel fuel will grow in the next years. Green diesel – alkanes produced through deoxygenation (DO) with H2 of triglyceride-based biomasses – can help cover this demand sustainably. …”
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Association of tumour mutation burden with prognosis and its clinical significance in stage III gastric cancer by Ya-Lin Han, Li Chen, Xu-Ning Wang, Mao-Lin Xu, Rui Qin, Fang-Ming Gong, Peng Sun, Hong-Yi Liu, Zhi-Peng Teng, Zhao-Xia Li, Guang-Hai Dai

“…Methods: Patients with stage III GC were divided into a high TMB and low TMB group in both a study cohort of 38 patients and the Cancer Genome Atlas (TCGA) cohort of 173 patients. In the study cohort, next-generation sequencing was used to detect mutated GC genes and obtain TMB data. …”
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Possible linking and treatment between Parkinson’s disease and inflammatory bowel disease: a study of Mendelian randomization based on gut–brain axis by Beiming Wang, Xiaoyin Bai, Yingmai Yang, Hong Yang

“…Then, pleiotropic analysis under the composite null hypothesis (PLACO) with functional mapping combined with annotation of genetic associations (FUMA) analysis were conducted to identify pleiotropic genes. Next, blood, brain and intestine expression quantitative trait locus (eQTL) were taken to perform drug-target MR finding common causal genes in two diseases. …”
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Extracellular vesicles contribute to the beneficial effects of exercise training in APP/PS1 mice by Oliver K. Fuller, Emma D. McLennan, Casey L. Egan, Nimna Perera, Lauren V. Terry, Jae Pyun, Mariana de Mendonca, Guilherme Defante Telles, Benoit Smeuninx, Emma L. Burrows, Ghizal Siddiqui, Darren J. Creek, John W. Scott, Michael A. Pearen, Pamali Fonseka, Joseph A. Nicolazzo, Suresh Mathivanan, Anthony J. Hannan, Grant A. Ramm, Martin Whitham, Mark A. Febbraio

“…Here, we first examined the effect of voluntary exercise training (VET) on energy metabolism and cognitive function in the APP/PS1 transgenic mouse (Tg) model of familial AD. Next, we profiled extracellular vesicles (EVs) and examined whether they may play a role in the protective effects of VET via intranasal administration of EVs, purified from the blood of sedentary (sEV) and/or acutely exercised (eEV) donor wild-type mice into APP/PS1Tg mice. …”
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Development and external validation of a dynamic nomogram for predicting the risk of functional outcome after 90 days in patients with acute intracerebral hemorrhage by Shaojie Li, Hongjian Li, Jiani Chen, Baofang Wu, Jiayin Wang, Chaocan Hong, Changhu Yan, Weizhi Qiu, Yasong Li, Hongzhi Gao

“…Background and purposeIntracerebral hemorrhage remains a significant cause of death and disability worldwide, highlighting the urgent need for accurate prognostic assessments to optimize patient management. …”
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An Unusually Short Latent Period of Therapy-Related Myeloid Neoplasm Harboring a Rare MLL-EP300 Rearrangement: Case Report and Literature Review by Reina Takeda, Kazuaki Yokoyama, Seiichiro Kobayashi, Toyotaka Kawamata, Sousuke Nakamura, Tomofusa Fukuyama, Mika Ito, Nozomi Yusa, Eigo Shimizu, Nobuhiro Ohno, Rui Yamaguchi, Seiya Imoto, Satoru Miyano, Kaoru Uchimaru, Arinobu Tojo

“…Bone marrow examinations revealed chronic myelomonocytic leukemia-like disease with a chromosomal translocation of t(11;22)(q23;q13) as a solo cytogenetic abnormality, resulting in the diagnosis of t-MN. Next-generation sequencing analysis identified a rare chimeric transcript, MLL-EP300, without any additional somatic mutations. …”
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Reducing peak thermo-electricity energy demand in building: Insights from sensible and latent storage – Applicable in hot and arid regions by Wajdi Rajhi, Noreen Izza Arshad, Naoufel Kraiem, Ahmed Mir, Lioua Kolsi, Ahmad H. Milyani, Mohammed N. Ajour, Hesham A. Alhumade, Aliakbar Karimipour

“…Owing to using the sensible-based approach, not only was the electricity consumption completely cut during critical hours, but the peak hour was postponed to the early hours of the next day (i.e., load shifting). Based on the results, using the first technique does not necessarily lead to peak shaving. …”
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