Vehicle Turn Pattern Counting and Short Term Forecasting Using Deep Learning for Urban Traffic Management System by Sundarakrishnan Narayanan, Sohan Varier, Tarun Bhupathi, Manaswini Simhadri Kavali, Mohana, P. Ramakanth Kumar, K. Sreelakshmi

“…These results highlight the effectiveness of our custom designed framework in real-world scenarios as a reliable model for applications needing high-precision detection and predictive analytics.…”
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Human blood cell transcriptomics unveils dynamic systemic immune modulation along colorectal cancer progression by Pedro J Romero, Mauro Delorenzi, Amaia Martínez-Usatorre, Laura Ciarloni, Noushin Hadadi, Eric Durandau, Sylvain Monnier-Benoit, Paolo Angelino, Victoria Wosika, Alessandra Jordano Conforte, Sara S Fonseca Costa, Hector Fabio Satizabal, Jérémie Despraz, Andres Perez-Uribe, Stephan Morgenthaler, Brian Hashemi, Sahar Hosseinian-Ehrensberger

“…Here we propose the host immune response to the onset of cancer as an alternative approach for early detection of CRC.Methods We perform whole transcriptome analysis of peripheral blood mononuclear cells (PBMCs) isolated from individuals with CRC, precancerous lesions or negative colonoscopy in two independent cohorts using next-generation sequencing.Results We discover and validate novel early CRC RNA biomarkers. …”
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Spot Urine Estimations Are Equivalent to 24-Hour Urine Assessments of Urine Protein Excretion for Predicting Clinical Outcomes by Boon Wee Teo, Ping Tyug Loh, Weng Kin Wong, Peh Joo Ho, Kwok Pui Choi, Qi Chun Toh, Hui Xu, Sharon Saw, Titus Lau, Sunil Sethi, Evan J. C. Lee

“…Patients with CKD (n=232) provided 24 hr urine collections followed by spot urine samples the next morning. We created multiple linear regression models to assess the factors associated with GFR decline (median follow-up: 37 months, IQR 26–41) and constructed Cox proportional-hazards models for predicting the combined outcome of ESRD and death. …”
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Distinct genome stabilization procedures lead to phenotypic variability in newly generated interspecific yeast hybrids by Pablo Murath, Pablo Murath, Stephanie Hoffmann, Beatriz Herrera-Malaver, Beatriz Herrera-Malaver, Beatriz Herrera-Malaver, Luis Bustamante, Kevin Verstrepen, Kevin Verstrepen, Kevin Verstrepen, Jan Steensels, Jan Steensels, Jan Steensels

“…We generated seven de novo interspecific hybrids between two S. eubayanus strains and an ale S. cerevisiae strain, subsequently exposing them to three different genome stabilization procedures. Next, we analyzed the fermentation characteristics and metabolite production of selected stabilized hybrids. …”
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Biochemical Pattern of Methylmalonyl-CoA Epimerase Deficiency Identified in Newborn Screening: A Case Report by Evelina Maines, Roberto Franceschi, Francesca Rivieri, Giovanni Piccoli, Björn Schulte, Jessica Hoffmann, Andrea Bordugo, Giulia Rodella, Francesca Teofoli, Monica Vincenzi, Massimo Soffiati, Marta Camilot

“…The analysis of methylmalonic pathway genes by next-generation sequencing (NGS) allowed the identification of the known homozygous nonsense variation c.139C>T (p.R47X) in exon 2 of the MCE gene. …”
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Prevalence of neutropenia in the U.S. among reproductive-aged women: a population-based analysis of NHANES 2013–2020 by Junfeng Chen, Shuangna Song, Yiran Li

“…Multivariate logistic regression was performed next, and weighted odds ratios along with the 95% confidence interval values were calculated, which assisted in predicting the prevalence of neutropenia among the female participants. …”
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A Resource-Efficient Multi-Entropy Fusion Method and Its Application for EEG-Based Emotion Recognition by Jiawen Li, Guanyuan Feng, Chen Ling, Ximing Ren, Xin Liu, Shuang Zhang, Leijun Wang, Yanmei Chen, Xianxian Zeng, Rongjun Chen

“…Then, such entropies are fused into a matrix to represent complex and dynamic characteristics of EEG, denoted as the Brain Rhythm Entropy Matrix (BREM). Next, Dynamic Time Warping (DTW), Mutual Information (MI), the Spearman Correlation Coefficient (SCC), and the Jaccard Similarity Coefficient (JSC) are applied to measure the similarity between the unknown testing BREM data and positive/negative emotional samples for classification. …”
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The effect of meningococcal vaccines on new generation of systemic inflammatory markers in children by Omer Okuyan, Neval Elgormus, Seyma Dumur, Ugurcan Sayili, Hafize Uzun

“…Results: Of the 464 participants, 58.2% were male, with a mean age of 3.81 years, and both sex ratios and ages were similar across the Nimenrix and Bexsero groups. …”
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Maximizing the clinical utility and performance of cytology samples for comprehensive genetic profiling by David Kim, Chad M. Vanderbilt, Soo-Ryum Yang, Subhiksha Nandakumar, Khedoudja Nafa, Rusmir Feratovic, Natasha Rekhtman, Ivelise Rijo, Jacklyn Casanova, Anita Yun, A. Rose Brannon, Michael F. Berger, Marc Ladanyi, Oscar Lin, Maria E. Arcila

“…Abstract Comprehensive molecular profiling by next-generation sequencing has revolutionized tumor classification and biomarker evaluation. …”
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Burden trends and future predictions for hypertensive heart disease attributable to non-optimal temperatures in the older adults amidst climate change, 1990–2021 by Can Xu, Xinyu Nie, Rui Xu, Ge Han, Dongjin Wang

“…However, heat-related HHD burden demonstrated a marked upward trend, projected to continue rising over the next two decades, particularly in low-income and tropical regions. …”
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Fractal cycles of sleep, a new aperiodic activity-based definition of sleep cycles by Yevgenia Rosenblum, Mahdad Jafarzadeh Esfahani, Nico Adelhöfer, Paul Zerr, Melanie Furrer, Reto Huber, Famke F Roest, Axel Steiger, Marcel Zeising, Csenge G Horváth, Bence Schneider, Róbert Bódizs, Martin Dresler

“…Fractal or aperiodic neural activity is a well-established marker of arousal and sleep stages measured using electroencephalography. We introduce a new concept of ‘fractal cycles’ of sleep, defined as a time interval during which time series of fractal activity descend to their local minimum and ascend to the next local maximum. …”
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Store Separation: Photogrammetric Solution for the Static Ejection Test by Luiz Eduardo Guarino de Vasconcelos, Nelson Paiva Oliveira Leite, André Yoshimi Kusumoto, Leandro Roberto, Cristina Moniz Araujo Lopes

“…With such information, it is possible to decide whether the next store release can be done with the required safety and/or whether the model used to estimate the separation trajectory is valid or not. …”
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Damage evolution of slab tracks with complex temperature distribution by Yang Li, Kailin Cao, Jinjie Chen, Haiyan Li, Zhihao Yang, Guocui Wang

“…The distribution of damage on the interface between track slabs and mortar layers also varies depending on the temperature assumptions. (3) The maximum compression damage of the pre-damaged T-shaped concrete joint decreases with increasing vertical nonlinearity and lateral gradient. These new findings are of significant theoretical importance as they emphasize the need to consider temperature distribution characteristics that have been overlooked in previous studies. …”
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<i>Pseudomonas aeruginosa pqs</i> Quorum Sensing Mediates Interaction with <i>Mycobacterium abscessus</i> In Vitro by Yun Long, Zhi Li, Menglu Li, Peiyi Lu, Yujia Deng, Pengyao Wu, Xue Li, Gangjian Qin, Jiamin Huang, Wenying Gao, Guobao Li, Tianyuan Jia, Liang Yang

“…In this study, we first demonstrated that <i>P. aeruginosa</i> inhibits the growth of <i>M. abscessus</i> by iron chelating via <i>pqs</i> quorum sensing. Next, through proteomic analysis, we discovered that the PQS molecule significantly changed a large amount of protein expression in <i>M. abscessus</i>, including proteins involved in the type VII secretion system and iron homeostasis. …”
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A Deep Learning Framework for the Classification of Brazilian Coins by Debabrata Swain, Viral Rupapara, Amro Nour, Santosh Satapathy, Biswaranjan Acharya, Shakti Mishra, Ali Bostani

“…First, a pre-processing module handles coin localization and image enhancement to mitigate variations in lighting and background. Next, an RFE-CNN-based feature extractor extracts discriminative features from the coin images. …”
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Enhanced Activity by NKCC1 and Slc26a6 Mediates Acidic pH and Cl− Movement after Cardioplegia-Induced Arrest of db/db Diabetic Heart by Minjeong Ji, Seok In Lee, Sang Ah Lee, Kuk Hui Son, Jeong Hee Hong

“…These transporters should be considered as potential therapeutic targets to develop the next generation of cardioplegia solution for protection against ischemia-reperfusion injury in diabetic hearts.…”
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Trunk muscle behaviors during the full-cycle stoop and squat lifting tasks by Fumin Pan, Wei Wang, Chao Kong, Shibao Lu

“…The absolute EMG was greatest during stage 2, then during stage 4, stages 1 and 3 came next (Effect size = 0.879, P < 0.001). The median values of the normalized EMG of each muscle during stoop lifting were also non-significantly lower than those during squat lifting at each stage (P > 0.05). …”
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Crispant analysis in zebrafish as a tool for rapid functional screening of disease-causing genes for bone fragility by Sophie Debaenst, Tamara Jarayseh, Hanna De Saffel, Jan Willem Bek, Matthieu Boone, Ivan Josipovic, Pierre Kibleur, Ronald Y Kwon, Paul J Coucke, Andy Willaert

“…Six genes linked to severe recessive osteogenesis imperfecta (OI) and four associated with bone mineral density (BMD) from genome-wide association studies were analyzed using CRISPR/Cas9-based crispant screening in F0 mosaic founder zebrafish. Next-generation sequencing confirmed high indel efficiency (mean 88%), mimicking stable knock-out models. …”
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Pasado y presente de la Teología de la Liberación en América Latina by Belkiss Elena Comas Martínez, Mario Antonio Padilla Torres

“…Aquí se caracteriza lo común entre sus máximos exponentes; se hace énfasis en los problemas sociales, desde una praxis liberadora, por las propias condiciones sociales de vida de estos creyentes revolucionarios, en nexo con su fe, y en cómo hacen uso del instrumental metodológico del marxismo; se destaca la valía de la TL, entre otros movimientos revolucionarios y progresistas en dicha región, sin desconocer las limitantes y diferencias entre cada una de las posiciones, así como su actuación social. …”
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Cytomegalovirus infection in an immunocompetent host presenting as haemophagocytic lymphohistiocytosis by Inês Matias-Lopes, Henrique Atalaia Barbacena, Margarida Guiomar, Raquel Soares, Catarina Barão, Ana Rita Ferreira, Federica Parlato, Patrícia Howell-Monteiro

“…Altogether, the clinical and laboratory presentation of this case reinforces the need for high clinical suspicion.…”
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