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17461
Current Trends in Mortality Attributable to Racial or Ethnic Disparities in Post-Surgical Population in The United States: A Population-Based Study
Published 2023-12-01“…For Hispanics, the annualized reduction needed is 0.8%. Conclusions:. Our data provides a framework for incorporating population and health systems measures for eliminating disparity in surgical mortality within the next decade.…”
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17462
Combination of rapamycin and adipose-derived mesenchymal stromal cells enhances therapeutic potential for osteoarthritis
Published 2025-01-01“…First, rapamycin effects on senescence and fibrosis markers were investigated in freshly isolated OA chondrocytes by immunostaining. Next, the in vitro differentiation capacities of AD-MSCs, their regulatory immune functions on activated immune cells and their regenerative effects on OA chondrocyte signature were assessed in the presence of rapamycin. …”
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17463
Genomic characterization and molecular predictive biomarkers for chemotherapy in patients with metastatic triple-negative breast cancer treated in a real-world setting
Published 2025-02-01“…Patients and methods: Next-generation sequencing with FoundationOne® CDx was conducted primarily on primary tumor tissue from 112 consecutive patients with mTNBC. …”
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17464
Assessment of historical and future changes in temperature indices for winegrape suitability in Hungarian wine regions (1971–2100)
Published 2025-02-01“…In the most optimistic scenario, the average temperature during the growing season may decrease by 0.8°C over the next seven decades. However, in the most pessimistic model, the change expected by the end of the century exceeds a 4.0°C increase. …”
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17465
Developing a decision support tool to predict delayed discharge from hospitals using machine learning
Published 2025-01-01“…Alternative Level of Care (ALC) patients who no longer need acute care yet face discharge barriers contribute to prolonged stays and hospital overcrowding. …”
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17466
Understanding the regulatory-procurement interface for medicines in Africa via publicly available information on standards, implementation, and enforcement in five countries
Published 2025-12-01“…Finally, none of the five countries have publicly published the results of their selection decisions with key product details, making it difficult to assess whether basic quality standards are being met.Conclusion Based on these findings, one of the most important next steps for improving the effectiveness and transparency of national procurement is for procurement agencies to publish detailed quality selection criteria and an up-to-date list of the medical products they have purchased, with key product information. …”
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17467
User-Centric Radio Access Technology Selection: A Survey of Game Theory Models and Multi-Agent Learning Algorithms
Published 2021-01-01“…Moreover, novel issues introduced by next-generation communication systems also need to be addressed. …”
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17468
Cryogenic and in situ characterization techniques for electrode interphase analysis
Published 2025-01-01“…There is an urgent need to develop innovative electrochemical energy storage devices that can offer high energy density, long lifespan, excellent rate capability, and improved security. …”
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17469
Streptococcus suis-associated neonatal meningitis and sepsis: characterization, antimicrobial resistance, and public health implications
Published 2025-01-01“…Streptococcus (S.) suis was isolated from cerebrospinal fluid and blood. Next-generation sequencing revealed that the strain was serotype 2 sequence type 1, and contained the ermB and tet(W) genes, which are responsible for resistance to macrolides and tetracycline, along with several pilus-associated genes and 20 virulence factors. …”
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17470
Comparative Analysis of Multicriteria Decision-Making Methods for Bus Washing Process Selection: A Case Study
Published 2024-01-01“…To achieve these objectives, the problem was approached as a case study in a public transport company in Portugal and the methodology followed the next steps: started with the identification of the different types of commercial technical solutions for washing buses; the company’s experts selected four main criteria: water consumption, operating costs, quality of washing, and time spent; the criteria weights were determined using the fuzzy-AHP method; then four representative MCDM methods were selected, namely, AHP, ELECTRE, TOPSIS, and SMART; the ranks obtained for the four methods were compared; and a sensitivity analysis was performed. …”
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17471
Changes in grocery shopping behaviour among low-income households during the COVID-19 pandemic
Published 2025-01-01“…Findings suggest that low-income households will continue to shop online, affirming the need for policies that promote equitable access to healthy food online. …”
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17472
Sequencing Analysis of Invasive Carbapenem-Resistant <i>Klebsiella pneumoniae</i> Isolates Secondary to Gastrointestinal Colonization
Published 2025-01-01“…All the patients who had dissemination episodes were furtherly investigated through next-generation sequencing, analyzing both colonizing and disseminating strains. …”
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17473
Disorders of circadian rhythms of heart rate variability in diabetic cardiac autonomic neuropathy: mechanisms and consequences
Published 2024-12-01“…Damage to the autonomic nerves results in dysfunction in heart rate control and vascular dynamics, particularly in cardiac autonomic neuropathy (CAN). …”
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17474
Assessment of dermal sensitization by nickel salts in a novel humanized TLR-4 mouse model
Published 2024-12-01“…In the LLNA, hTLR-4-positive mice of both sexes exhibited enhanced responsivity to nickel. …”
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17475
Nanotechnology and LSTM machine learning algorithms in advanced fuel spray dynamics in CI engines with different bowl geometries
Published 2025-01-01“…This interdisciplinary approach provides a robust framework for designing next-generation CI engines with improved efficiency and sustainability. …”
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17476
Influence of strength and power training on the rate of force development, peak force and functional mobility in elderly people with Parkinson's disease: a randomized controlled tr...
Published 2025-01-01“…FM was also assessed using the following tests: gait speed test (GS), Timed Up and Go (TUG), Short Physical Performance Battery (SPPB), Unified Parkinson's Disease Rating Scale (UPDRS); parallel feet on a force platform. Next, the participants underwent lower limbs muscle strength or muscle power training for eight consecutive weeks twice a week and were then re-evaluated.ResultsThe repeated measures ANOVA test showed a significant difference for PF, RFD and FM regardless of training type.ConclusionThe proposed muscle strength and muscle power training protocols influenced the increase in RFD, PF and FM of all participants; however, the increase in RFD in the first 200 ms was more pronounced in the groups submitted to power training and the increase in PF was more pronounced in the groups submitted to strength training.…”
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17477
Concurrent Intracranial and Spinal Subdural Hematoma in a Teenage Athlete: A Case Report of This Rare Entity
Published 2014-01-01“…In addition, he experienced a new left sided headache, fatigue, and difficulty ambulating. …”
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17478
Evaluation of the effect of Irritrol as final irrigant against Staphylococcus epidermidis: an in Vitro Study.
Published 2022-02-01“…All samples were prepared and instrumented by using ProTaper NEXT rotary system till X3. 5.25% NaOCl was applied with a 27‐G double side‐vented syringe needle as an initial irrigant then followed by the final irrigants. …”
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17479
Incomplete human reference genomes can drive false sex biases and expose patient-identifying information in metagenomic data
Published 2025-01-01“…Abstract As next-generation sequencing technologies produce deeper genome coverages at lower costs, there is a critical need for reliable computational host DNA removal in metagenomic data. …”
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17480
Molecular dynamics and machine learning unlock possibilities in beauty design—A perspective
Published 2025-01-01“…Computational molecular design—the endeavor to design molecules, with various missions, aided by machine learning and molecular dynamics approaches—has been widely applied to create valuable new molecular entities, from small molecule therapeutics to protein biologics. …”
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