Brain network and energy imbalance in Parkinson’s disease: linking ATP reduction and α-synuclein pathology by Hirohisa Watanabe, Sayuri Shima, Kazuya Kawabata, Yasuaki Mizutani, Akihiro Ueda, Akihiro Ueda, Mizuki Ito, Mizuki Ito

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Impact of pharmacist-prescriber partnerships to track antibiotic prescribing in publicly funded primary care in the Cape Town metropole, South Africa: An implementation study by O Van Hecke, Y Adegoke, M Allwood, K von Pressentin, M Namane, C Butler, M Mendelson, R Coetzee

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Role of the Specialized Proresolving Mediator Resolvin D1 in Systemic Lupus Erythematosus: Preliminary Results by Luca Navarini, Tiziana Bisogno, Domenico Paolo Emanuele Margiotta, Alessandra Piccoli, Silvia Angeletti, Alice Laudisio, Massimo Ciccozzi, Antonella Afeltra, Mauro Maccarrone

“…RvD1 plasma levels were measured by ELISA according to the manufacturer’s protocol (Cayman Chemical Co.). RvD1 levels were compared using Mann–Whitney test. …”
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T Cell-Derived Apoptotic Extracellular Vesicles Ameliorate Bone Loss via CD39 and CD73-Mediated ATP Hydrolysis by Yang X, Zhou Y, Zhou F, Bao L, Wang Z, Li Z, Ding F, Kuang H, Liu H, Tan S, Qiu X, Jing H, Liu S, Ma D

“…Xiaoshan Yang,1– 3,* Yang Zhou,2,3,* Fuxing Zhou,4,* Lili Bao,2,3 Zhengyan Wang,5 Zihan Li,2,3 Feng Ding,2,3 Huijuan Kuang,6,7 Huan Liu,8 Shenglong Tan,1 Xinyuan Qiu,1 Huan Jing,9 Shiyu Liu,2,3 Dandan Ma1 1Department of Endodontics, Stomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou, 510280, People’s Republic of China; 2State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi Key Laboratory of Stomatology, Department of Oral Biology, School of Stomatology, The Fourth Military Medical University, Xi’an, 710032, People’s Republic of China; 3State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi International Joint Research Center for Oral Diseases, Center for Tissue Engineering, School of Stomatology, The Fourth Military Medical University, Xi’an, 710032, People’s Republic of China; 4Department of Gynecology and Obstetrics, Xijing Hospital, The Fourth Military Medical University, Xi’an, 710032, People’s Republic of China; 5Department of Orthodontics, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, Jinan, 250012, People’s Republic of China; 6Department of Orthopaedics, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, 710061, People’s Republic of China; 7State Key Laboratory for Manufacturing System Engineering, Xi’an Jiaotong University, Xi’an, 710054, People’s Republic of China; 8Department of Otolaryngology Head and Neck Surgery, Peking University Third Hospital, Beijing, 100871, People’s Republic of China; 9Department of Endodontics, Guangdong Provincial High-level Clinical Key Specialty, Guangdong Province Engineering Research Center of Oral Disease Diagnosis and Treatment, Peking University Shenzhen Hospital, Shenzhen, 518036, People’s Republic of China*These authors contributed equally to this workCorrespondence: Dandan Ma, Stomatological Hospital, Southern Medical University, S366 Jiangnan Boulevard, Guangzhou, Guangdong, 510280, People’s Republic of China, Tel +86-20-34152996, Email mdd@smu.edu.cn Shiyu Liu, School of Stomatology, The Fourth Military Medical University, No. 145, West Changle Road, Xi’an, Shaanxi, 710032, People’s Republic of China, Tel +86-29-84772645, Email liushiyu@vip.163.comBackground: Osteoporosis is a major public health concern characterized by decreased bone density. …”
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Naoxintong Is Involved in the Coagulation Regulation of Warfarin Through the MAPK Pathway by Luo X, Chen L, Xu J, Li J

“…Xiao Luo,1,2,* Ling Chen,2,* Jingsong Xu,1 Juxiang Li1 1Department of Cardiovascular Medicine, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, 330000, People’s Republic of China; 2Department of Cardiovascular Medicine, Jiujiang City Key Laboratory of Cell Therapy, Jiujiang No. 1 People’s Hospital, Jiujiang, Jiangxi, 332000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Juxiang Li, Department of Cardiovascular Medicine, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, No. 1, Minde Road, Donghu District, Nanchang, Jiangxi, 330000, People’s Republic of China, Tel +86 15707923841, Email ndefy87008@ncu.edu.cnObjective: To explore the effect of Naoxintong (NXT) on warfarin anticoagulation therapy and its potential mechanism.Methods: TCSMP, SwissTargetprediction, SuperPred, SEA, and Batmanic-TCM were used to search for active ingredients and targets of NXT and warfarin; the DisGENT database was used to find disease targets of coagulation disorders. …”
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Characterization and DNA barcoding of Zambian plant species used as inoculum in the traditional fermentation of Munkoyo; a cereal-based beverage by Mubonda Kalumbilo, David Chuba, Agripina Banda, Eddy J. Smid, Sijmen E. Schoustra, Gerlinde B. De Deyn

“…., Rhynchosia heterophylla Hauman, and Eminia holubii (Hemsl.) Taub. Root colour differed among these species, with the Rhynchosia species having yellowish roots and E. holubii having whitish roots. …”
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Escherichia coli in the T11-12 Thoracic Vertebrae: A Case Report by Weng D, Zhou H, Huang G, Cao Q, Wang H, Cao Z, Xie Q

“…Dandan Weng,1,* Hongyuan Zhou,1,* Guancheng Huang,1 Qingren Cao,2 Huafeng Wang,3 Zhujun Cao,2 Qing Xie2 1Department of Infectious Diseases, Yuyao People’s Hospital, Ningbo, Zhejiang, People’s Republic of China; 2Department of Infectious Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 3Department of Pathology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qing Xie; Zhujun Cao, Department of Infectious Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, People’s Republic of China, Email xieqingrjh@163.com; estherlucifer@163.comBackground: Pyogenic thoracic spondylitis is a rare but severe infection, particularly when complicated by sepsis and acute kidney injury (AKI). …”
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Digital Sensory Marketing Sebagai Upaya Meningkatkan Daya Saing Produk UMKM by Amelia Putri, Alwan Husni Ramdani, Aliya Nurul Fauziah, Muhammad Vickry Affryansyah, Gesha Fadhillah Ramdhan

“…Transaksi jual beli secara online memunculkan permasalahan baru yakni, ketidaksesuaian barang dangan spesifikasi yang diperjanjikan. Di era digital aktifitas live stream shopping menjadi salah satu solusi atas permasalahan tersebut dan juga strategi inovatif untuk meningkatkan daya saing produk UMKM. …”
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Disruption of Gut Microbiota and Associated Fecal Metabolites in Collagen-Induced Arthritis Mice During the Early Stage by Wu D, Yin M, Cao D, Zhang X, Zhu Y, Wei Y, Li Y, Wen C, Zhou J

“…Dehong Wu,1,* Mengdi Yin,2,* Dandan Cao,2,* Xiafeng Zhang,2 Yichun Zhu,2 Ying Wei,2 Yiling Li,2 Chengping Wen,2 Jia Zhou2 1Department of Rheumatology, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, 310005, People’s Republic of China; 2Institute of Basic Research in Clinical Medicine, College of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, 310053, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jia Zhou; Chengping Wen, Email zhoujia@zcmu.edu.cn; chengpw2010@126.comBackground: Rheumatoid arthritis (RA) is a chronic autoimmune disease and increasing evidence suggests that disturbances in the composition and function of gut microbiota are potentially implicated in the progression of RA. …”
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Variación estacional de los Thripidae en los montes de cerezo y la vegetación asociada al cultivo en el Valle Inferior del Río Chubut, Argentina by J. RODRIGUEZ, P. NEIRA, P. CARRIZO

“…Entre marzo de 2009 y 2010 se relevaron 2 chacras en Gaiman, con las variedades Bing, Lapins, New Star, Sunburst y Stella. …”
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Kíkọ́ Àjòjì Ní Gírámà Èdè Yorùbá: Àkóónú Àti Ọgbọ́n-Ìkọ́ni by Harrison Adeniyi

“… O pon dandan lati wa ona ti awon ajoji ti won nifee lati ko ati lati mo ede Yoruba yoo gba ti yoo fi ro won lorun lai si pe kiko ede Yoruba n ko won lominu. …”
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Genetic associations of plasma metabolites with immune cells in hyperthyroidism revealed by Mendelian randomization and GWAS-sc-eQTLs xQTLbiolinks analysis by Yutong Li, Xingyu Song, Yuyang Huang, Sifan Zhou, Linkun Zhong

“…In this study, we acquired 731 immune cell phenotypes from genome-wide association studies (GWAS) (n = 18,622), HD data from the research by Handan Melike Dönertaş et al. (3,731 cases, 480,867 controls), and aggregated statistics of 1,400 blood metabolites from UK Biobank (n = 115,078). …”
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Klasifikasi Jenis Ikan Laut K-Nearest Neighbor Berdasarkan Ekstraksi Ciri 2-Dimensional Linear Discriminant Analysis by Yusraka Dimas Al Iman, R Rizal Isnanto, Oky Dwi Nurhayati

“… Indonesia adalah suatu negara kepulaun yang memiliki 2/3 wilayah lautan, secara sektor indonesia memiliki potensi pangan yang sangan besar dalam sektor perikanan. Ikan di dunia yang berhasil diuraikan sebanyak 27.000 terutama paling banyak dilaut indonesai. …”
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Development of a machine learning-based prediction model for extremely rapid decline in estimated glomerular filtration rate in patients with chronic kidney disease: a retrospectiv... by Shingo Fukuma, Yukio Yuzawa, Daijo Inaguma, Hiroki Hayashi, Ryosuke Yanagiya, Akira Koseki, Toshiya Iwamori, Michiharu Kudo

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Florencia en el "desierto de las tribulaciones". Notas sobre Jerónimo Savonarola, profeta del bien común histórico by Piero Venturelli

“…El fraile anuncia que Dios lo ha elegido para indicar a los fl orentinos el camino espiritual y moral en el "desierto de las tribulaciones" que conduce a la Tierra Prometida, del mismo modo que había espoleado a Israel, trámite la voz de Moisés, a huir de Egipto y a ponerse en marcha en dirección a Canaán. El nacimiento de una república "ampliada" en Florencia en diciembre de 1494 marca uno de los primeros éxitos tangibles de la predicación savonaroliana, quien exhorta a los ciudadanos a afi nar con el tiempo la nueva constitución a fin de volverla cada vez más impermeable a todo eventual intento de renovación de la tiranía. …”
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Bevezetés „A tudat aspektusai” című tematikus rovat elé by Bence Marosán

“…A blokk szerzői közül hárman már jelentős teljesítményt maguk mögött tudó, a hazai filozófiai élet meghatározó szereplői közé tartoznak (Dornbach Márton, Horváth Lajos, Popovics Zoltán), ketten pedig még pályájuk viszonylag kezdeti szakaszán álló, kimagasló tehetségű kutatók (Sípos Andrea, Berta Gergely). …”
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Exploring Self-Management Behavior Profiles in Patients with Multimorbidity: A Sequential, Explanatory Mixed-Methods Study by Fu Y, Wu J, Guo Z, Shi Y, Zhao B, Yu J, Chen D, Wu Q, Xue E, Du H, Zhang H, Shao J

“…Yujia Fu,1,2,* Jingjie Wu,3,* Zhiting Guo,4 Yajun Shi,1 Binyu Zhao,1,2 Jianing Yu,1,2 Dandan Chen,3 Qiwei Wu,1,2 Erxu Xue,3 Haoyang Du,3 Huafang Zhang,1 Jing Shao1,2 1Department of Nursing, the Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University, Yiwu, People’s Republic of China; 2School of Nursing and Institute of Nursing Research, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People’s Republic of China; 3Department of Nursing, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, People’s Republic of China; 4Department of Nursing, The Second Affiliated Hospital of Zhejiang University School of Medicine (SAHZU), Hangzhou, Zhejiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jing Shao, Zhejiang University School of Medicine, 866 Yuhangtang Road, Hangzhou, 310058, People’s Republic of China, Email 11318202@zju.edu.cnPurpose: This study aims to identify self-management behavior profiles in multimorbid patients, and explore how workload, capacity, and their interactions influence these profiles.Patients and Methods: A sequential explanatory mixed-methods design was employed. …”
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Èdè Àyàn: The Language of Àyàn in Yorùbá Art and Ritual of Egúngún by Oláwọlé Fámúlẹ̀

“…Another Yorùbá saying that illustrates that ìlù is an instrument of language substitution is “that the gángan drum could speak in a human nasal tone of 1 Onílù is formed from two Yorùbá words oní and ìlù (literally, “owner of the drum” or “one who plays the drum”), a euphemism for the drummer. …”
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Relationship between four healthy lifestyle factors and all-cause and cardiovascular disease mortality among residents aged 35 – 75 years in Hebei province by Yuhuan LIU, Lijuan TANG, Xiaoying LU, Jingjing ZHAO, Yajing CAO, Xiaoli LIU, Dongsheng JIANG

“…MethodsData were collected from 48 377 residents aged 35 – 75 years in 11 districts and counties of Hebei province (Daming county, Handan city; Qinghe county, Xingtai city; Xuanhua district, Zhangjiakou city; Yuhua district, Shijiazhuang city; Chengde county, Chengde city; Sanhe city, Langfang city; Quyang county, Baoding city; Huanghua city, Cangzhou city; Shenzhou city, Hengshui city; Zunhua city, Tangshan city; and Funing district, Qinhuangdao city) who participated in the National Early Screening and Comprehensive Intervention Program for High-Risk Populations of CVD from September 2016 to December 2022. …”
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Development of Solid Self-Nanoemulsifying Drug Delivery System of Rhein to Improve Biopharmaceutical Performance: Physiochemical Characterization, and Pharmacokinetic Evaluation by More SM, Rashid MA, Kharwade RS, Taha M, Alhamhoom Y, Elhassan GO, Gangane P, Asar TO, Pise A, Kaleem M, Mujtaba MA

“…Sachin Madhusudan More1 *, Md Abdur Rashid,2 Rohini S Kharwade3 *, Murtada Taha,4 Yahya Alhamhoom,2 Gamal Osman Elhassan,5 Purushottam Gangane,3 Turky Omar Asar,6 Ajay Pise,7 Mohammed Kaleem,1 Md Ali Mujtaba8,9 1Department of Pharmacology, Dadasaheb Balpande College of Pharmacy, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, MH, 440037, India; 2Department of Pharmaceutics, College of Pharmacy, King Khalid University, Abha, Saudi Arabia; 3Department of Pharmaceutics, Dadasaheb Balpande College of Pharmacy, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, MH, 440037, India; 4Department of Clinical Laboratory Science, Prince Sultan Military College of Health Sciences, Dhahran, Saudi Arabia; 5Department of Pharmaceutics, College of Pharmacy, Qassim University, Buraidah, Saudi Arabia; 6Department of Biology, College of Science and Arts at Alkamil, University of Jeddah, Jeddah, Saudi Arabia; 7Department of Regulatory Affairs Dadasaheb Balpande College of Pharmacy, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, MH, 440037, India; 8Department of Pharmaceutics, Faculty of Pharmacy, Northern Border University, Arar, Saudi Arabia; 9Center for Health Research, Northern Border University, Arar, Saudi Arabia* These authors contributed equally to this workCorrespondence: Md Ali Mujtaba; Mohammed Kaleem, Email m.mujtaba@nbu.edu.sa; kaleemmubin88@gmail.comIntroduction: Rhein, a natural bioactive lipophilic compound with numerous pharmacological activities, faces limitations in clinical application due to poor aqueous solubility and low bioavailability. …”
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