Analysis of fatty acid-derived lipids in critically ill patients after cardiac surgery yields novel pathophysiologically relevant mediators with possible relevance for systemic inf... by Holger Neb, Verena Roth, Jessica Roos, Jessica Roos, Tom Bauer, Anja Urbschat, Ulrike Heinicke, Carlo Angioni, Dieter Steinhilber, Dieter Steinhilber, Matthias Piesche, Matthias Piesche, Nerea Ferreirós, Robert Gurke, Robert Gurke, Gerd Geisslinger, Gerd Geisslinger, Edith Utech, Kai Zacharowski, Patrick Meybohm, Patrick Meybohm, Patrick Paulus, Elke Schmitt, Elke Schmitt, Thorsten Jürgen Maier, Thorsten Jürgen Maier

“…Furthermore, 6-keto-PGF1alpha had its peak shortly before initiation of continuous veno-venous hemodialysis (at least in 5 of the observed patients), 2-AG was elevated in all our nine patients during (right) heart failure in the context of either re-opening patient’s chest, implementation of veno-arterial ECMO or at least while significantly increasing the amount of catecholamines.DiscussionIn this pilot trial we identified several evaluated lipids in critically ill patients representing either potentially (patho-) physiologically relevant mediators of the pro-inflammatory processes and during heart failure or possible markers preceding veno-venous hemodialysis.…”
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Interaction of human gut microbiota and local immune system in progression of colorectal adenoma (MIMICA-1): a protocol for a prospective, observational cohort study by Jurate Valciukiene, Egle Lastauskiene, Aida Laurinaviciene, Aida Laurinaviciene, Matas Jakubauskas, Marius Kryzauskas, Ruta Barbora Valkiuniene, Ruta Barbora Valkiuniene, Renaldas Augulis, Renaldas Augulis, Ausra Garnelyte, Justinas Kavoliunas, Ugne Silinskaite, Tomas Poskus

“…The intestinal immune system response will be examined using digital image analysis where primarily immunohistochemistry procedures for CD3, CD8, CD20 and CD68 immune cell markers will be performed. Thereafter, the count, density and distribution of immunocompetent cells in epithelial and stromal tissue compartments will be evaluated using AI-based platform. …”
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Utilisation et résistance d’un nouveau jouet introduit chez des macaques cynomolgus hébergés en milieu standard ou appauvri by Helen Beyer, Agnès Loison, Fanélie Wanert

“…Concernant la résistance, l’un des jouets a été fortement abimé en seulement deux semaines à cause de morsures chez le groupe de mâles adultes. Toutefois, la résistance et la flexibilité qu'offre cette nouvelle gamme de jouets sont très satisfaisantes pour une utilisation chez des PNH, hormis pour les animaux à grandes canines.…”
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Unveiling the antiurolithiatic potentiality of two benzene sulfonamide derivatives against ethylene glycol-induced renal calculi by Ahmed M. Elgendy, Mohamed S. Nafie, Zohour I. Nabil, Nahla S. El-Shenawy, Heba N. Gad El-Hak

“…This division enabled a comparative analysis between rats with kidney stones and those without, offering insights into the effects of kidney stone induction on various physiological parameters and biochemical markers. The effectiveness of benzene sulfonamide derivatives (compounds A and B) was assessed in rats with induced kidney stones. …”
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Détection de différents rétrovirus chez des primates non-humains infectés par STLV-1 ou SFV et pathologie viro-induite by Jocelyn Turpin, Sandrine Alais, Ambroise Marçais, Olivier Hermine, Réjane Rua, Antoine Gessain, Romain Lacoste, Renaud Mahieux

“…Notre travail visait (1) à étudier la potentielle transmission zoonotique des virus STLV-1 et SFV par morsure en quantifiant la présence de ces virus par PCR en temps réel (STLV-1) ou par nested-PCR (SFV et STLV-1) dans la salive et dans le sang (contrôle), (2) à développer un protocole de traitement des animaux développant un ATL. …”
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Potential Antidepressant Effects of Omeprazole Introduced Through Network Analysis and Systems Biology Should Be Interpreted with Caution in the Clinical Environment by Seyed-Ali Mostafavi

“…In conclusion, the methodology for the identification of the link between genetic markers and medications initially proposed in this paper provides a strong groundwork for subsequent research; while also pointing at the need to pay sufficient care to the side effects of medications like Omeprazole on the patient’s mental state. …”
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Effects of Electroacupuncture at Zusanli and Quchi on Neurological Function Recovery in Rats with Cerebral Infarction by Jiangcong HONG, Yingzheng WANG, Guangwen WU, Yulong ZOU

“…In addition, BrdU-positive cells, double positive cells of BrdU/DCX and double positive cells of BrdU/NeuN were used as markers of proliferation, migration and differentiation of neural stem cells, respectively. …”
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Local factors determining the response to antiangiogenic therapy with first-line drugs in macular neovascularization by V.G. Likhvantseva, S.G. Kapkova, E.B. Tretyak, S.I. Rychkova, A.S. Gevorkyan, T.E. Borisenko

“…</p> <p> <b>Results</b>: improvement of MNV activity markers in the setting of treatment manifested as reduction in area and height of subretinal fluid (k=0.9432, p&lt;0.01, and k=0.58959, p&lt;0.001), reduction in height and area of retinal pigment epithelium (RPE) detachment (k=0.82808, p&lt;0.05; k=0.50221, p&lt;0.05) and reduction in sub-RPE fluid (k=0.84515, p&lt;0.05) were strongly directly correlated with baseline IOP. …”
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Mangrove plants using deoxyribonucleic acid barcodes for enhancing biodiversity and conservation by M. Basyuni, R. Syahbana, A.B. Rangkuti, N.A. Pradisty, A. Susilowati, L.A.M. Siregar, S.S. Al Mustaniroh, A.A. Aznawi, A. Mubaraq, E.R. Ardli, S.H. Larekeng, V. Leopardas, Y. Isowa, T. Kajita

“…The significant differences were as follows: inter- and intraspecific genetic distance (probability (p) <0.001), maturase-K (probability = 0.0001), combination maturase-K + photosystem II reaction center protein A (probability = 0.0008), maturase-K + ribulose 1,5-bisphosphate carboxylase/oxygenase (probability = 0.0008), maturase-K + internal transcribed spacer (probability = 0.0003), ribulose 1,5-bisphosphate carboxylase/oxygenase + internal transcribed spacer (probability = 0.0002), photosystem II reaction center protein A + internal transcribed spacer (probability = 7.051e-05), and three combined markers maturase-K + photosystem II reaction center protein A + internal transcribed spacer (probability = 0.0007). …”
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Comparative analysis of C-Reactive protein levels among Non-comorbid, Comorbid, and Multimorbid Hospitalized COVID-19 patients by Maria Shoukat, Haseeb Khan, Moona Nazish, Abdur Rehman, Sheharyar Raashid, Saad Ahmed, Wajid Munir, Abdulwahed Fahad Alrefaei, Massab Umair, Muhammad Osama Bin Abid, Nasim Akhtar, Wajid Zaman, Malik Badshah

“…Abstract Background C-reactive protein (CRP) is one of the most commonly monitored inflammatory markers in patients with COVID-19 to gain insight into the inflammation level in the body and to adopt effective disease management and therapeutic strategies. …”
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À propos des foyers protohistoriques à pierres chauffantes en Provence-Alpes-Côte d’Azur by Denis Dubesset

“…Archaeological data (spatial arrangement, location within a specific area, site specialization, long chronology, structures intended for the community, etc.) and ethnological data make it possible to consider the largest groupings of hearths as strong territorial markers wherein links to political and religious power might be be achieved by the association of several habitat units.…”
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Effect of Lymphatic Drainage Manipulation on Knee Joint Swelling after Anterior Cruciate Ligament Reconstruction by MENG Cong, BAO Yong, ZHANG Weiming

“…Range of motion (ROM) and knee function [Lysholm knee score scale (LKSS)] before and after intervention for both groups were observed, as well as changes in pain substances [substance P, 5-hydroxytryptamine (5-HT)] and inflammatory markers [tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6)].ResultsThe swelling degree of knee joint in the observation group was lower than that in the control group at 1, 2 and 4 weeks postoperatively (<italic>P</italic>&lt;0.05). …”
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