Optimizing selenium-enriched yeast supplementation in laying hens: Enhancing egg quality, selenium concentration in eggs, antioxidant defense, and liver health by Longfei Zhang, Jianmin Zhou, Uchechukwu Edna Obianwuna, Cheng Long, Kai Qiu, Haijun Zhang, Xiaolong Qi, Shugeng Wu

“…This study evaluated the effects of selenium-enriched yeast (SY) supplementation at various levels on health and production parameters in laying hens, including egg production, egg quality, selenium (Se) concentrations in eggs, liver health, serum biochemical markers, antioxidant function, and immune responses. …”
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Effects of a liquefied petroleum gas stove and fuel intervention on head circumference and length at birth: A multi-country household air pollution intervention network (HAPIN) tri... by Hina Raheel, Sheela Sinharoy, Anaité Diaz-Artiga, Sarada S. Garg, Ajay Pillarisetti, Kalpana Balakrishnan, Marilu Chiang, Amy Lovvorn, Miles Kirby, Usha Ramakrishnan, Shirin Jabbarzadeh, Alexie Mukeshimana, Michael Johnson, John P. McCracken, Luke P. Naeher, Ghislaine Rosa, Jiantong Wang, Joshua Rosenthal, William Checkley, Thomas F. Clasen, Jennifer L. Peel, Lisa M. Thompson

“…Background: Air pollution may impair child growth and cognitive development, with potential markers including birth length and head circumference. …”
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Effects of Carbonate Alkalinity on Antioxidants, Immunity and Intestinal Flora of <i>Penaeus vannamei</i> by Chuang Gao, Zhonghong Li, Bo Ma, Rantao Zuo, Xudong Shen, Mingkang Chen, Chuanqi Ren, Wenjun Zheng, Zhonglu Cai, Jiaxing Li, Shuang Li

“…The activity of antioxidant enzymes was determined by enzyme markers, and then the intestinal microorganisms of <i>Penaeus vannamei</i> were analyzed by high-throughput sequencing technology. …”
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N-acetylcysteine increased the growth performance of Leuciscus waleckii by improving mitochondrial function, enhancing antioxidant and anti-inflammatory, and inhibiting apoptosis i... by Deng Lai Li, Rui Zhu, Si Tong Meng, Yin Tao Wang, Si Ying Liu, Zhi Yong Yang, Li Fang Wu

“…NAC supplementation upregulates the mRNA expression of Claudin-3, Claudin-f, ZO-1, and Occludin-a and reduces intestinal permeability-related markers, thereby maintaining intestinal physical barrier function. …”
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Sex differences in epigenetic ageing for older people living with HIVResearch in context by Carrie D. Johnston, Alina P.S. Pang, Eugenia L. Siegler, Charlene Thomas, Chelsie O. Burchett, Mia Crowley, Rochelle O'Brien, Lishomwa C. Ndhlovu, Marshall J. Glesby, Michael J. Corley

“…We found epigenetic age acceleration associated with plasma proteomic markers involved in inflammation, senescence, immune regulation, kidney function, and tissue homoeostasis (p < 0.0001). …”
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Therapeutic depletion of CCR8+ tumor-infiltrating regulatory T cells elicits antitumor immunity and synergizes with anti-PD-1 therapy by James Dooley, Bart Neyns, Elizabeth Allen, Frank Tacke, Louis Boon, Damya Laoui, Julia Katharina Schwarze, Helena Van Damme, Bruno Dombrecht, Máté Kiss, Heleen Roose, Eva Van Overmeire, Daliya Kancheva, Liesbet Martens, Aleksandar Murgaski, Pauline Madeleine Rachel Bardet, Gillian Blancke, Maude Jans, Evangelia Bolli, Maria Solange Martins, Yvon Elkrim, Kiavash Movahedi, Niels Vandamme, Sebahat Ocak, Isabelle Scheyltjens, Lars Vereecke, Frank Aboubakar Nana, Pascal Merchiers, Jo Agnes Van Ginderachter

“…The therapeutic use of these Nb-Fc fusion proteins was evaluated, either as monotherapy or as combination therapy with anti-programmed cell death protein-1 (anti-PD-1), in both the LLC-OVA and MC38 mouse models.Results We were able to discern two ti-Treg populations, one of which is characterized by the unique expression of Ccr8 in conjunction with Treg activation markers. Ccr8 is also expressed by dysfunctional CD4+ and CD8+ T cells, but the CCR8 protein was only prominent on the highly activated and strongly T-cell suppressive ti-Treg subpopulation of mouse and human tumors, with no major CCR8-positivity found on peripheral Tregs. …”
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Vaccarin suppresses diabetic nephropathy through <?A3B2 pi6?>inhibiting the EGFR/ERK1/2 signaling pathway by Zhu Xuexue, Meng Xinyu, Du Xinyao, Zhao Chenyang, Ma Xinyu, Wen Yuanyuan, Zhang Shijie, Hou Bao, Cai Weiwei, Du Bin, Han Zhijun, Xu Fei, Qiu Liying, Sun Haijian

“…RT-PCR is utilized to quantify the mRNA levels of renal fibrosis, oxidative stress and inflammation markers. The levels of malondialdehyde (MDA) and reactive oxygen species (ROS), as well as the content of glutathione peroxidase (GSH-Px), are measured. …”
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Unraveling the immunological landscape and gut microbiome in sepsis: a comprehensive approach to diagnosis and prognosisResearch in context by Yali Luo, Jian Gao, Xinliang Su, Helian Li, Yingcen Li, Wenhao Qi, Xuling Han, Jingxuan Han, Yiran Zhao, Alin Zhang, Yan Zheng, Feng Qian, Hongyu He

“…In addition, T cell phenotypes within adaptive immunity are correlated with sepsis severity and may serve as reliable prognostic markers. Funding: This project was supported by the National Key R&D Program of China (2023YFC2307600, 2021YFA1301000), Shanghai Municipal Science and Technology Major Project (2023SHZDZX02, 2017SHZDZX01), Shanghai Municipal Technology Standards Project (23DZ2202600).…”
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Deciphering hub genes and immune landscapes related to neutrophil extracellular traps in rheumatoid arthritis: insights from integrated bioinformatics analyses and experiments by Yang Li, Yang Li, Jian Liu, Jian Liu, Yue Sun, Yue Sun, Yuedi Hu, Yuedi Hu, Qiao Zhou, Qiao Zhou, Chengzhi Cong, Chengzhi Cong, Yiming Chen, Yiming Chen

“…Correlation analysis further emphasized close associations between hub genes and laboratory markers in patients with RA.ConclusionThis study first elucidated neutrophil heterogeneity in the RA synovial microenvironment and mechanisms of communication with fibroblasts. …”
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Immunomodulatory Effects of Combination Therapy with Bushen Formula plus Entecavir for Chronic Hepatitis B Patients by Long-Shan Ji, Qiu-Tian Gao, Ruo-Wen Guo, Xin Zhang, Zhen-Hua Zhou, Zhuo Yu, Xiao-Jun Zhu, Ya-Ting Gao, Xue-Hua Sun, Yue-Qiu Gao, Man Li

“…Biochemical assessment, viral load quantitation, and HBV markers were tested. Chinese medicine symptom complex score was evaluated and recorded as well. …”
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Effect of dietary microalgae on growth performance and health in meat-type quails by Samar M. Mohamed, Mahmoud Alagawany, Mohamed S. El-Kholy, Mohamed M. El-Mekkawy, Ayman S. Salah, Youssef A. Attia, Rashed A. Alhotan, Alessandro Di Cerbo, Antonia Lestingi

“…Liver and kidney function markers were affected by the supplements, and DsAp2 group recorded the highest levels of total protein and albumin. …”
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The Potential Proallergenic Activity of Tranzschelia pruni-spinosae and Phragmidium rubi-idaei in vitro Studies by Sztandera-Tymoczek M, Wdowiak-Wróbel S, Świderska U, Palusińska-Szysz M, Szuster-Ciesielska A

“…Immunofluorescence techniques were employed to assess cell integrity markers.Results: Extracts from T. pruni-spinosae and P. rubi-idaei significantly stimulated the production of proinflammatory cytokines IL-1β and GM-CSF in both cell lines, all of which are associated with the development of allergic responses. …”
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Serum hsa-miR-22-3p, hsa-miR-885-5p, Lipase-to-Amylase Ratio, C-Reactive Protein, CA19-9, and Neutrophil-to-Lymphocyte Ratio as Prognostic Factors in Advanced Pancreatic Ductal Ade... by Jakub Wnuk, Dorota Hudy, Joanna Katarzyna Strzelczyk, Łukasz Michalecki, Kamil Dybek, Iwona Gisterek-Grocholska

“…The selected miRNAs and LAR were not confirmed as reliable prognostic markers in PC.…”
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Poly (ADP-ribose) (PAR) levels in Peripheral Blood Mononuclear Cells (PBMC) during peri-implantation and early pregnancy in buffalo cows by Giovanna De Matteis, Anna Reale, Michele Zampieri, Emanuela Rossi, Federica Signorelli, Olimpia Barbato, Vittoria Lucia Barile

“…Since its involvement in the blastocyst implantation has been hypothesized and considered the importance of markers for predicting pregnancy success, with this study, we wanted to evaluate dynamic changes in PAR levels during peri-implantation and early pregnancy in peripheral blood mononuclear cells (PBMCs) in buffalo species. …”
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Cocktail of Ropivacaine, Morphine, and Diprospan Reduces Pain and Prolongs Analgesic Effects after Total Knee Arthroplasty: A Prospective Randomized Controlled Trial by Zhenyu Luo, Weinan Zeng, Xi Chen, Qiang Xiao, Anjing Chen, Jiali Chen, Haoyang Wang, Zongke Zhou

“…The primary outcomes were the levels of inflammatory markers C-reactive protein (CRP) and interleukin-6 (IL-6), pain visual analog scale (VAS) scores, opioid consumption, range of motion (ROM), functional tests, and sleeping quality. …”
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Features of pancreatic parenchyma fibrosis in the comorbid course of chronic pancreatitis and chronic obstructive pulmonary disease by I.V. Dudka, O.S. Khukhlina, T.V. Dudka, O.Y. Hryniuk, V.O. Pavliuk

“…The study also used data from a clinical blood analysis, a biochemical study of the content of markers of the syndrome of deviation of the pancreas enzymes in the blood, the content of elastase-1 in feces, ultrasonographic examination of abdominal organs, changes in the carbohydrate-pro­tein components of the extracellular matrix, the state of collagenolytic activity of the blood plasma. …”
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Study of the hereditary non-syndromic ophthalmological pathology of child population of the Karachay-Cherkess Republic: estimations of genetic load and molecular genetic analysis by V.V. Kadyshev, A.V. Marakhonov, S.I. Kutsev, R.A. Zinchenko

“…Region-specific molecular genetic markers for the hereditary pathology of the organ of vision are not established at this stage.…”
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Effects of organic acid blends on the growth performance, intestinal morphology, microbiota, and serum lipid parameters of broiler chickens by Swapnali Waghmare, Mahesh Gupta, K.B. Bahiram, J.P. Korde, Rekha Bhat, Yashwant Datar, Pushpendra Rajora, M.M. Kadam, Megha Kaore, N.V. Kurkure

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Exploring the clinical value of procalcitonin, c-reactive protein, white blood cell count, and neutrophil-to-lymphocyte ratio in the early diagnosis of bloodstream infections in ch... by Yadong Li, Mingjie Li, Chenye Lin, Wentao Tang, Qiuyu Tang, Feng Cheng

“…Abstract Backgroud In the diagnosis of bloodstream infections (BSI) in children, compared to the gold standard of blood culture, markers in the blood offer advantages such as rapid results and cost-effectiveness. …”
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Mechanism of Acupuncture Therapy on RANKL/OPG Signaling Pathway to Regulate Bone Metabolism Balance in Osteoporosis Model Rats by Qin YIN, Hong PAN, Xiaojuan DING, Xiaoguang QIN, Xiaorong GUO

“…Sp), structural model index(SMI)were analyzed by Micro-CT;TUNEL method was used to detect apoptosis of distal femur cells in four groups;Western blot and RT-PCR method were used to detect the protein expression levels of RANKL, OPG mRNA in femur and hypothalamus in four groups.Results:①BMD and bone metabolism markers: compared with the blank group, BMD, BALP, CBF-α1, CTX-I, PINP and OC in the model group were significantly decreased(<italic>P</italic>&lt;0.05). …”
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