Epidemiology, clinical spectrum, and outcomes of severe malaria in Eastern Uganda: a prospective study by Cate Namayanja, George Paasi, Jimmy Patrick Alunyo, Denis Amorut, Charles Benard Okalebo, William Okiror, Paul Ongodia, Grace Abongo, Rita Muhindo, Yovani A. M. Lubaale, Peter Olupot-Olupot

“…Laboratory analyses included complete blood counts, lactate, glucose, blood gases, electrolytes, metabolites, and coagulation markers. In addition, urinalysis using dipsticks was done. …”
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Development of normal reference intervals for renal function in pregnancy: a secondary analysis of clinical trial data by Zandile Legoabe, Motshedisi Sebitloane, Carl Lombard, Megeshinee Naidoo, Glenda Gray, Dhayendre Moodley

“…We aimed to establish reference values for commonly used markers of renal function in healthy pregnant women of African origin.Methods Pregnant women ≥18 years, not living with HIV, and at 14–28 weeks gestation were enrolled in a PrEP clinical trial in Durban, South Africa between September 2017 and December 2019. …”
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Does Sex Matter in Obesity-Induced Periodontal Inflammation in the SS^LepR Mutant Rats? by Abdulmohsin Alhashim, Kim Capehart, Jocelyn Tang, Karim M. Saad, Rafik Abdelsayed, Marion A. Cooley, Jan M. Williams, Ahmed A. Elmarakby

“…Plasma thiobarbituric acid reactive substances (TBARs) and monocyte chemoattractant protein-1 (MCP-1), markers of systemic oxidative stress and inflammation, respectively, were significantly elevated in obese SS^LepR mutant rats vs. lean SS rats, with no sex differences in these parameters in either rat strains. …”
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Interplay between BMI, neutrophil, triglyceride and uric acid: a case-control study and bidirectional multivariate mendelian randomization analysis by Haoyuan Lyu, Na Fan, Hao Wen, Xin Zhang, Herong Mao, Qinglai Bian, Jiaxu Chen

“…By integrating Spearman correlation analysis with various MR study designs, this study provided a robust framework for identifying key factors influencing hyperuricemia and related health issues, thereby enhancing our understanding of the interplay between inflammatory markers and these health indicators. Conclusions Our study presents strong evidence of the complex interconnection between BMI, neutrophils, triglyceride, and UA, revealing complex causal links and highlighting potential inflammatory states as key mediators. …”
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Impact of behavior change theory-based nursing interventions on cardiac function recovery and quality of life among cardiac surgery patients with cardiopulmonary bypass by Youwei Zhao, Wei Wei, Zhiyuan Wang, Yanbo Dong, Zhenyu Su, Shichao Guo

“…Regarding inflammatory markers, TNF-α and IL-6 levels were significantly reduced in the observation group, while IL-10 levels were significantly elevated compared to the control group (P < 0.05). …”
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Risk Factors and Pharmacological Interventions Impacting Cerebrovascular Ischemic Events in Giant Cell Arteritis: A Narrative Review by Muhammad Osama Siddiqui, Mohammad Ali Syed, Ayaan Ahmed Qureshi, Mustafa Hussain Imam, Jatin Motwani, Verkha Kumari, Arooba Siddiqui, Noor Ul Ain, Mohammed Hammad Jaber

“…Results Findings indicate that age, male gender, hypertension, and smoking significantly increase the risk of GCA‐related CIE, while factors such as anemia, higher body mass index (BMI), and elevated inflammatory markers (C‐reactive protein [CRP] and erythrocyte sedimentation rate [ESR]) appear to have protective effects. …”
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Preterm preeclampsia screening and prevention: a comprehensive approach to implementation in a real-world setting by Stefania Ronzoni, Shamim Rashid, Aimee Santoro, Elad Mei-Dan, Jon Barrett, Nanette Okun, Tianhua Huang

“…Risk for preterm preeclampsia was assessed using the Fetal Medicine Foundation algorithm, which includes maternal risk factors, uterine artery Doppler, mean arterial pressure and serum markers (Placental growth factor, PlGF and Pregnancy-associated plasma protein-A, PAPP-A). …”
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Seroprevalence characteristics of hepatitis E virus among blood donors infected with hepatitis B virus by YU Qin, XU Tingting, YANG Hao, ZHAO Lei

“…[Methods] From January to December 2022, 219 samples positive for hepatitis B surface antigen (HBsAg), 142 occult hepatitis B virus infection (OBI) samples (HBV group) and 873 samples tested negative (control group) were collected. 361 samples were further tested with viral load assay and serological testing for five serological markers (HBsAg, HBsAb, HBeAg, HBeAb and HBcAb), and the DNA load was measured using real time fluorescence quantitative PCR. …”
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Migrasomes derived from human umbilical cord mesenchymal stem cells: a new therapeutic agent for ovalbumin-induced asthma in mice by Weifeng Gu, Tingting Zheng, Wen Li, Xinkai Luo, Xiaowei Xu, Ying Wang, Chaoming Mao, Yongbin Ma, Liyang Dong

“…We successfully isolated hUCMSC-migrasomes, which were morphologically intact and positive for the specific migrasomes markers. The administration of hUCMSC-migrasomes was observed to significantly ameliorate the symptoms of airway inflammation and mucus production in asthmatic mice. …”
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Temporal Changes in Plasmodium Falciparum Genetic Diversity and Multiplicity of Infection Across Three Areas of Varying Malaria Transmission Intensities in Uganda. by Mwesigwa, Alex, Kiwuwa, Steven M., Musinguzi, Benson, Kawalya, Hakiim, Katumba, James Davis, Baguma, Andrew, Mutuku, Irene M., Adebayo, Ismail Abiola, Nsobya, Samuel L., Byakika‐Kibwika, Pauline, Kalyango, Joan N., Karamagi, Charles, Nankabirwa, Joaniter I.

“…Genotyping utilized seven polymorphic markers: Poly-α, TA1, TA109, PfPK2, 2490, C2M34–313, and C3M69–383. …”
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Oxyresveratrol as a novel ferroptosis inducer exhibits anticancer activity against breast cancer via the EGFR/PI3K/AKT/GPX4 signalling axis by Lei Xiang, Qingzhou Li, Zhiwei Guan, Guilin Wang, Xiankuo Yu, Xianwen Zhang, Guochen Zhang, Jushan Hu, Xue Yang, Mingrui Li, Xilinqiqige Bao, Yumei Wang, Dong Wang

“…Bioinformatics tools were used to predict the anticancer activity and MOA of ORes. Ferroptosis markers (ferrous ions, reactive oxygen species, lipid peroxidation, and GPX4 expression) were assessed, and mitochondrial morphology was observed. …”
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Antibody-based delivery of interleukin-2 modulates the immunosuppressive tumor microenvironment and achieves cure in pancreatic ductal adenocarcinoma syngeneic mice by Carmine Carbone, Roberto De Luca, Emanuele Puca, Antonio Agostini, Alessia Caggiano, Lorenzo Priori, Annachiara Esposito, Serena Ascrizzi, Geny Piro, Lisa Salvatore, Francesco De Sanctis, Stefano Ugel, Vincenzo Corbo, Dario Neri, Giampaolo Tortora

“…Spatial Transcriptomics (ST) and RNA-seq analyses indicated that L19-IL2 treatment induced a significant influx of immune cells into the tumor microenvironment, with these cells expressing activation markers like granzymes, perforins, and the IL-2 receptors. …”
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Impact of Preoperative and Intraoperative Factors on Postoperative Outcomes in Patients with Colorectal Cancer: A 10-Year Retrospective Study by Lucian Flavius Herlo, Ioana Golu, Alexandra Herlo, Claudia Raluca Balasa Virzob, Ionescu Alin, Stela Iurciuc, Ionut Eduard Iordache, Luana Alexandrescu, Doina Ecaterina Tofolean, Raluca Dumache

“…Conclusions: Preoperative inflammatory markers, nutritional status, ASA score, comorbidities, and intraoperative factors like blood loss significantly influence postoperative outcomes in colorectal cancer surgery. …”
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Shedding light on the existence of Furan fatty acids in latex lipids across a wide diversity of Hevea brasiliensis genotypes by Chaisiri Kitpaosong, Siriluck Liengprayoon, Erwann Durand, Tucksin Lerksamran, Aurélie Daval, Eric Gohet, Lim Khan Tiva, Phean Chetha, Kong Mengchheang, Phen Phearun, Ung Rattana, Kim Chandy, Pol Sokea, Un Kim Eng, Kittipong Rattanaporn, Bruno Barea, Laurent Vaysse

“…Notably, the biochemical markers of natural rubber productivity (sucrose, inorganic phosphorus, thiols, and total solid content) showed no direct involvement in furan fatty acid biosynthesis during latex regeneration between tappings. …”
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Potential Mechanisms and Effects of Dai Bai Jie Ethanol Extract in Preventing Acute Alcoholic Liver Injury by Niantong Xia, Hongwei Xue, Yihang Li, Jia Liu, Yang Lou, Shuyang Li, Yutian Wang, Juan Lu, Xi Chen

“…For this purpose, alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) levels were assessed, liver function indices and oxidative and inflammatory markers were determined, and histopathological examinations were performed. …”
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A practical distribution pattern of α-SMA-positive carcinoma associated fibroblasts indicates poor prognosis of patients with pancreatic ductal adenocarcinoma by Bo Li, Meilong Shi, Yang Wang, Penghao Li, Xiaoyi Yin, Guoxiao Zhang, Xiaochao Kang, Huan Wang, Suizhi Gao, Kailian Zheng, Xiaohan Shi, Xiongfei Xu, Yukun Zhou, Hui Jiang, Wei Jing, Shiwei Guo, Gang Jin

“…We used tumor specimens to screen out the most suitable markers for the spatial distribution analysis for CAFs subpopulations. …”
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Revealing the biological features of the axolotl pancreas as a new research model by Hui Ma, Hui Ma, Hui Ma, Guangcong Peng, Yan Hu, Binbin Lu, Binbin Lu, Yiying Zheng, Yingxian Wu, Weimin Feng, Yu Shi, Xiangyu Pan, Li Song, Ina Stützer, Yanmei Liu, Jifeng Fei, Jifeng Fei, Jifeng Fei

“…Pancreatic development was observed using in situ hybridization and immunostaining for key pancreatic markers. RNA sequencing was performed to profile global gene expression during larva and adult stages. …”
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Changes in clinical and imaging variables during withdrawal of heart failure therapy in recovered dilated cardiomyopathy by Brian P. Halliday, Ruth Owen, John Gregson, Ali Vazir, Rebecca Wassall, Zohya Khalique, Amrit S. Lota, Upasana Tayal, Daniel J. Hammersley, Richard E. Jones, Dudley J. Pennell, Martin R. Cowie, John G.F. Cleland, Sanjay K. Prasad

“…Abstract Aims This study aimed to profile the changes in non‐invasive clinical, biochemical, and imaging markers during withdrawal of therapy in patients with recovered dilated cardiomyopathy, providing insights into the pathophysiology of relapse. …”
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Role of Vitamin D Status and Alterations in Gut Microbiota Metabolism in Fibromyalgia-Associated Chronic Inflammatory Pain by Caterina Saija, Maria Paola Bertuccio, Alberto Scoglio, Vincenzo Macaione, Francesco Cacciola, Giuseppe Micalizzi, Daniela Caccamo, Carolina Muscoli, Monica Currò

“…We aimed to investigate the relationship between vitamin D status and gut dysbiosis markers in fibromyalgia (FM)-associated chronic inflammation. …”
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Exploration of the mechanism of Lithospermum erythrorhizon oil in treating atopic dermatitis based on network pharmacology and experimental validation of the PI3K-Akt pathway regul... by Weisheng Hu, Yinlan Wang, Yingjie Zhou, Junbao Shi, Zengyan Li, Xiaoling Jiang, Qinyuan Wu, Changming Zhong, Huilan Weng, Sijie Ouyang, Yuan Jing, Xianxiang Cai, Mingda Ye, Ning Huang

“…An AD mouse model induced by DNCB was established to evaluate Lithospermum erythrorhizon oil's therapeutic efficacy, its influence on inflammatory markers, and the PI3K-Akt pathway. Results: Fifteen common targets were found to be crucial in AD pathogenesis. …”
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