Terminal complement complex deposition on chondrocytes promotes premature senescence in age- and trauma-related osteoarthritis by Leonie Ruths, Jana Hengge, Graciosa Q. Teixeira, Melanie Haffner-Luntzer, Anita Ignatius, Jana Riegger

“…Gene and protein expression of senescence-associated markers such as CDKN1A and CDKN2A was determined.ResultsIn the murine aging model, CD59-ko mice developed after 72 weeks more severe OA compared to C6-deficient and WT mice. mRNA analysis revealed that the expression of Cdkn1a, Cdkn2a, Tp53, Il1b, and Il6 was significantly increased in the cartilage of CD59-ko mice. …”
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Neutrophil Extracellular Trap Components Associate with Infarct Size, Ventricular Function, and Clinical Outcome in STEMI by Ragnhild Helseth, Christian Shetelig, Geir Øystein Andersen, Miriam Sjåstad Langseth, Shanmuganathan Limalanathan, Trine B. Opstad, Harald Arnesen, Pavel Hoffmann, Jan Eritsland, Ingebjørg Seljeflot

“…We explored the temporal profile of circulating NET markers and their associations to myocardial injury and function and to adverse clinical events in STEMI patients. …”
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Comparison of thromboelastographic profiles and clinical characteristics in children with severe Mycoplasma pneumoniae pneumonia by Yong-tao Li, Yu-mei Ma, Fu-li Dai, Zhen Peng, Ya-ping Dai, Ke Zhi, Hai-hong Feng, Shu-jun Li

“…They also required longer azithromycin courses (median: 15 vs. 14 days, P = 0.026).ConclusionChildren with severe MP pneumonia and abnormal TEG profiles have more severe clinical manifestations, higher inflammatory markers, more extensive lung involvement, and a higher incidence of complications. …”
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Serological Evidence of Hepatitis B and E and Dengue Coinfection in Chadian Patients and Impact on Lipidemia Profile by Alexandre Kanga Djasrabe, Borris Rosnay Tietcheu Galani, Moussa Mahamat Ali, Fissou Henry Yandai, Bessimbaye Nadlaou, Mayann Habkreo, Nicolas Yanou Njintang

“…From February to May 2021, 179 subjects were recruited from the Department of Gastroenterology and Internal Medicine of the National Reference University Hospital of N’Djamena and tested for viral hepatitis markers, including HBsAg and IgM/IgG anti-HEV and dengue infection, using the NS1/IgM/IgG kit. …”
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Exosomes secreted by ATF3/Nrf2-mediated ferroptotic renal tubular epithelial cells promote M1/M2 ratio imbalance inducing renal interstitial fibrosis following ischemia and reperfu... by Qiao Tang, Jiatao Xie, Yifei Wang, Chong Dong, Chong Dong, Qian Sun

“…Moreover, there were higher levels of M2 markers (Arg1, TGF-β and IL-10 mRNA) in the IR group than those in the sham group, and lower levels in the IR+Fer-1 group or in the IR+ATF3KD group compared with the IR group. …”
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Composite cardiac computed tomography angiography score for improved risk assessment in chronic coronary syndromes by Subin Lee, Alexander Giesen, Dimitrios Mouselimis, Loris Weichsel, Andreas A. Giannopoulos, Max Nunninger, Matthias Renker, Florian André, Norbert Frey, Grigorios Korosoglou

“…A composite CCTA score, derived by these imaging markers may identify high-risk individuals, who may benefit from more intensified treatment and clinical follow-up in future studies.…”
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Like mother like daughter, the role of low human capital in intergenerational cycles of disadvantage: the Pune Maternal Nutrition Study by Akanksha A. Marphatia, Akanksha A. Marphatia, Jonathan C. K. Wells, Alice M. Reid, Aboli Bhalerao, Chittaranjan S. Yajnik

“…Few studies have evaluated whether maternal human and socio-economic capital at conception are independently associated with maternal and offspring outcomes.MethodsUsing data on 651 mother-child dyads from the prospective Pune Maternal Nutrition Study in rural India, composite markers were generated of “maternal human capital” using maternal marriage age and maternal and husband's education, and 'socio-economic capital' using household wealth and caste. …”
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Association of IL-8 and CXCR2 with AST/ALT Ratio in Liver Abnormalities Screening during Oxidative Stress Injury Caused by VCM by Yiwen Dong, Xingang Wang, Weijiang Hu, Xin Wang, Hongying Bian, Wencui Zhang, null Feng Han, Ning Kang, Lin Zhang, Meng Ye

“…ALT, AST, and AST/ALT ratio all contributed to liver abnormalities that contained fatty liver, liver calcification, and liver cysts, IL-8 and CXCR2 correlated with each other strongly and showed significant associations with oxidative stress markers, even AST/ALT ratio. IL-8 (>1547 µg/m3) or CXCR2 (<139 µg/m3) influenced the AST/ALT ratio through reciprocal interactions under oxidative stress injury, CXCR2 (>222 µg/m3), working years of 21 to 30 (a) and 11 to 20 (a), TDGA (>1.52 mg/L), alcohol consumption, smoking habit, and a less sleeping duration of <4 h per day would also be potential factors affecting the AST/ALT ratio. …”
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PERSEPSI PENGUNJUNG TERHADAP KENYAMANAN FASILITAS RUANG TERBUKA PUBLIK FORT ROTTERDAM by Ibrahim Tuahena, Triyatni Martosenjoyo, Abdul Mufti Radja

“…Facility variables invited in the study discussed paving, shade plants, kiosks, trash bins, lights, markers, and benches. The convenience variables discussed are physical comfort, namely physical studies and anthropometric studies on facilities, psychospiritual comfort that can be achieved by considering the comfort of air, plants, and good regional transportation, sociocultural comfort, namely comfort, social, and comfort such as aroma, circulation, climate, climate, security, security, regional lighting. …”
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Ten days of supplementation with a standardized Boswellia serrata extract attenuates soreness and accelerates recovery after repeated bouts of downhill running in recreationally ac... by Dawna Salter, Himana Yalamanchi, Aiswarya Yalamanchi, Amulya Yalamanchi

“…C-reactive protein and interleukin-6 increased after DHR, but by day 10, SBS reduced these markers compared to the PLA (p &lt; 0.05). This study suggests that SBS, a novel, standardized extract derived from the gum resin of B. serrata, improves recovery and reduces soreness following high-impact eccentric exercise.Clinical Trial Registrationhttps://ctri.nic.in/Clinicaltrials/pubview2.php, Clinical Trial Registry of India (CTRI/2019/07/020323).…”
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Association between Growth Hormone and Insulin-like Growth Factor-1 (IGF-1) Levels, Liver Function and Short-Term Survival of Paediatric Liver Recipients by R. M. Kurabekova, O. M. Tsiroulnikova, I. E. Pashkova, L. V. Makarova, N. P. Mozheiko, A. R. Monakhov, O. P. Shevchenko

“…Analysis of associations between growth hormone and IGF-1 levels in blood and markers of liver function and post-LT survival in children.Materials and methods. …”
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Blockades of effector T cell senescence and exhaustion synergistically enhance antitumor immunity and immunotherapy by Xia Liu, Emily Shaw, Fusheng Si, Guangyong Peng, Yan Tao, Feiya Ma, David Bagley, Yuanqin Zhang

“…Furthermore, T cell senescence induced by mouse tumor and regulatory T (Treg) cells in vitro was determined with multiple markers and assays, including real-time PCR, flow cytometry, and histochemistry staining. …”
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Arctiin Protects Chondrocytes from Interleukin-1β-Induced Inflammation and Apoptosis by RNA Sequence In vivo and In vitro by Yong-Jia Song, Jia-Min Bao, Zeng-Qiao Zhang, Yun-Xiang Hai, Hao-Nan Wen, Tian-Jun Zhai, Wei Feng, Min Song

“…Techniques such as biochemical assays, Enzyme-linked immunosorbent assay, quantitative real-time polymerase chain reaction (qRT-PCR), Western blotting, and immunofluorescence labeling were employed to detect changes in nitric oxide (NO), lactate dehydrogenase (LDH), inflammatory markers, and components of the cartilage matrix in chondrocytes. …”
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Genetically and chemically intraspecific variations of Ficus hirta provide novel insights into its protection and utilization by Jianling Chen, Qianqian Liu, Huihong Wang, Zhi Chao, Enwei Tian

“…Psoralen and bergapten were the differentiated quality markers among the groups. The medicinal quality of the populations NN, SD and HZ within southwestern group was much greater than that of the ND and GZ populations within southeastern group, which is consistent with the comprehensive quality scores for each origin (Y = 1.78 ~-0.82). …”
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Biology, Pathogenicity, and Genetic Diversity of the Rice Pathogen <i>Ustilaginoidea virens</i> in Heilongjiang Province, China by Peng Guo, Xiaofeng Xu, Yue Ma, Niaz Nihal, Mingxiu Yang, Zhe Ni, Younis Haseeb, Lei Hou, Anqi Lv, Junhua Zhang

“…The genetic diversity of 86 <i>U. virens</i> isolates was analyzed, and the tolerant varieties were identified using Rep-PCR molecular markers. The results indicated that among the <i>U. virens</i> isolates analyzed, about 31, 27 and 28 strains exhibited fast, medium and slow mycelium growth rates, respectively. …”
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Integrating Genomic Selection and a Genome-Wide Association Study to Improve Days Open in Thai Dairy Holstein Cattle: A Comprehensive Genetic Analysis by Akhmad Fathoni, Wuttigrai Boonkum, Vibuntita Chankitisakul, Sayan Buaban, Monchai Duangjinda

“…Moreover, the 12 identified potential candidate genes can be utilized in future studies to select markers for days open in regard to dairy cattle.…”
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Basolateral amygdala volume in affective disorders using 7T MRI in vivo by Benedikt Kürzinger, Stephanie Schindler, Martin Meffert, Anja Rosenhahn, Robert Trampel, Robert Turner, Peter Schoenknecht, Peter Schoenknecht, Peter Schoenknecht

“…Future research with larger sample sizes, including the measurement of genetic and epigenetic markers, will hopefully further elucidate this compelling paradigm.…”
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Effect of self-paced sprint interval training and low-volume HIIT on cardiorespiratory fitness: the role of heart rate and power output by Katie L. Hesketh, Katie L. Hesketh, Sam O. Shepherd, Anton J. M. Wagenmakers, Matthew Cocks, Juliette A. Strauss

“…Sessions were completed 3×/week using WattBikes, and a target of &gt;80% HRmax was suggested during the intervals. Markers of cardio-metabolic health were assessed before and after each intervention.ResultsTraining increased VO2peak (SIT +3.1 ± 0.4 mL kg−1 min−1, LV-HIIT +2.7 ± 1.2 mL kg−1 min−1, P &lt; 0.001) and decreased body fat % (P = 0.002), aortic pulse wave velocity (P = 0.002) and glucose tolerance 120 min following an oral glucose tolerance test (P = 0.024), with no difference between protocols (P &gt; 0.05). …”
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Facial Anthropometry and Self-expressed Behaviours: A Systematic Review by Ankit Srivastava, Vilas Chimurkar, Nisha Mani Pandey, Anand Bihari

“…Conclusion: The data from various populations in present review support the hypothesis that facial structures are important biological markers for assessing behaviours or personality traits. …”
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The expression of exosomal and cellular miRNAs in predicting oxaliplatin resistance in colorectal cancer cells: an in silico and in vitro study by Hoda Deli, Zeynab Vakili-Ghartavol, Yazdan Asgari, Gholamreza Tavoosidana, Ebrahim Eftekhar, Mohammad Hossein Ghahremani

“…This indicates the potential of these specific miRNAs to serve as predictive markers for the response to oxaliplatin therapy.…”
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