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7321
MSC-sEVs exacerbate senescence by transferring bisecting GlcNAcylated GPNMB
Published 2025-01-01“…Statistical methods were utilized to investigate the correlations between GPNMB expression, glycosylation modifications, and established senescence markers. Results Our findings demonstrate a robust positive correlation between the expression of GPNMB in BMMSCs and sEVs and the induction of cellular senescence. …”
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7322
Oxidative Stability at Different Storage Conditions and Adulteration Detection of Prickly Pear Seeds Oil
Published 2020-01-01“…The levels of adulteration detection using fatty acids as markers are relatively high. The detection of oil adulteration can be depicted by fatty acids composition up to 15% of olive and almond oils and up to 20% of rapeseed oil. …”
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7323
Biomarkers for Predicting Left Atrial or Left Atrial Appendage Thrombus in Anticoagulated Patients with Nonvalvular Atrial Fibrillation
Published 2020-01-01“…Therefore, these might be considered as useful prognostic markers in the management and treatment of NVAF patients.…”
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7324
Lung-delivered IL-10 therapy elicits beneficial effects via immune modulation in organic dust exposure-induced lung inflammation
Published 2024-12-01“…IL-10 therapy reduced ODE-associated expression of antigen presentation (MHC Class II, CD80, CD86) and inflammatory (Ly6C) markers and increased anti-inflammatory CD206 expression on CD11cintCD11b+ cells. …”
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7325
Domain‐Specific Prediction of Clinical Progression in Parkinson's Disease Using the Mosaic Approach
Published 2025-01-01“…Using MRI and clinical data from 135 recently diagnosed PD patients from the Parkinson's Progression Markers Initiative, we first defined an extremity‐specific motor score. …”
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7326
High Seroprevalence of Autoantibodies Typical of Autoimmune Liver Disease in Eastern Ethiopia: Is Chewing of Khat (Catha edulis) a Triggering Factor?
Published 2018-01-01“…Case series have found markers of autoimmune hepatitis in patients with khat-related liver disease, suggesting that khat chewing might trigger an autoimmune response. …”
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7327
Oxyberberine alleviates lipopolysaccharide-induced intestinal barrier disruption and inflammation in human colonic Caco-2 cells in vitro
Published 2025-01-01“…Moreover, OBB ameliorated the LPS-induced decrease in the distribution and expression of several tight junction markers, including ZO-1, occludin, and E-cadherin. …”
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7328
Effects of Age and Sex on Systemic Inflammation and Cardiometabolic Function in Individuals With Type 2 Diabetes
Published 2025-02-01“…Results For the 133 recruited individuals (44% women; median age, 71±7 years, 41% with T2D), the presence of T2D most significantly increased the white blood cell count (P=0.004; P.adj.=0.140) among markers of systemic inflammation. White blood cell count was comparable in men and women. …”
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7329
The role of Ashwagandha in modulating gut parameters in dogs—a randomized double-blind placebo-controlled trial
Published 2025-01-01“…Various parameters were assessed, including serum haematology, biochemical markers, stool parameters, and gut–microbiome parameters.ResultsThe erythrocyte counts and haemoglobin levels were significantly increased with ARE (p < 0.01 and p < 0.001). …”
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7330
Interactions between ABC gene polymorphisms and processing speed in predicting depression severity
Published 2025-02-01“…Conclusion The results suggest that ABC family genes influence the severity of depression through cognitive functioning, providing possible evidence for genetic markers in MDD patients.…”
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7331
Inflammatory Monocytes Are Rapidly Recruited to the Post-Ischaemic Liver in Patients Undergoing Liver Transplantation and Cytokines Associated with Their Activation Correlate with...
Published 2025-01-01“…Circulating cytokines were measured, and T cells were analysed for activation markers and cytokine production. <i>Results:</i> Circulating levels of cytokines associated with innate immune cell recruitment and activation were significantly elevated in the peri-transplant period. …”
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7332
Serum CD4 Is Associated with the Infiltration of CD4+T Cells in the Tumor Microenvironment of Gastric Cancer
Published 2021-01-01“…Serum CD4, CD8, and CD19 are markers of systemic inflammation. However, there is little evidence on the influence of inflammation on the tumor microenvironment and the prognostic indicators of gastric cancer (GC). …”
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7333
LncRNA TUG1 mitigates chronic kidney disease through miR-542-3p/HIF-1α/VEGF axis
Published 2025-01-01“…Additionally, knocking down lncRNA TUG1 has been shown to reduce the expression of fibrotic markers by alleviating tissue hypoxia. This effect was significantly counteracted by the inhibition of miR-542-3p. …”
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7334
Efficacy of hyperimmunized egg yolk antibodies (IgY) against Campylobacter jejuni: In Vitro and In Vivo evaluations
Published 2025-02-01“…Furthermore, medium and high doses of SIgY were effective in preserving the integrity of the intestinal epithelium, as evidenced by a reduction in crypt depth and the number of goblet cells, which serve as important markers in the immune system (P < 0.01). Additionally, analyses of cecal and liver bacterial counts in response to the 0.5 % SIgY treatment revealed a significant reduction in C. jejuni counts compared to other challenged groups throughout the 28 d experiment (P < 0.01). …”
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7335
Prognostic implications of immune classification based on PD-L1 expression and tumor-infiltrating lymphocytes in endocervical adenocarcinoma
Published 2025-02-01“…Tumor-infiltrating immune markers were assessed using immunohistochemistry. …”
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7336
The impact of Ramadan fasting on oxidative stress levels in the second trimester of pregnancy
Published 2024-12-01“…Obstetric ultrasound parameters showed no significant differences between the two groups (p < .05).Conclusions The present study suggests that fasting during the second trimester of pregnancy does not substantially impact maternal or foetal health, as indicated by most oxidative stress markers and foetal parameters studied. However, the observed reduction in the TAS levels in the fasting group warrants further investigation.…”
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7337
Left ventricular remodeling and its association with mineral and bone disorder in kidney transplant recipients
Published 2024-12-01“…The relationship between MBD and LV remodeling and the factors influencing LV remodeling were analyzed.Results One year after KT, MBD was partially improved, mainly characterized by hypercalcemia, hypophosphatemia, hyperparathyroidism, 25-(OH) vitamin D deficiency, elevated bone turnover markers, and bone loss. LVMI, the prevalence of left ventricular hypertrophy (LVH), and the prevalence of LVDD decreased, while LVEF increased. …”
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7338
Generation and characterization of two induced pluripotent stem cell lines (ICGi052-A and ICGi052-B) from a patient with frontotemporal dementia with parkinsonism-17 associated wit...
Published 2024-11-01“…The iPSC lines ICGi052-A and ICGi052-B proliferate stably, form colonies with a morphology characteristic of human pluripotent cells, have a normal diploid karyotype (46,XX), express endogenous alkaline phosphatase and pluripotency markers (OCT4, NANOG, SSEA-4 and TRA-1-60) and are able to differentiate into derivatives of three germ layers: ento-, ecto- and mesoderm. …”
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7339
Development and validation of predictive models of early immune effector cell–associated hematotoxicity
Published 2025-02-01“…Postinfusion laboratory markers associated with severe eICAHT included early and peak levels of inflammatory biomarkers (CRP, ferritin, and IL-6), coagulopathy biomarkers (D-dimer), peak cytokine release syndrome grade, and peak neurotoxicity grade. …”
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7340
Multidimensional features of sporadic Creutzfeldt-Jakob disease in the elderly: a case report and systematic review
Published 2024-04-01“…Neuropathological profiles in the cerebral cortex revealed vacuolar spongiosis, neuronal loss, gliosis, and aging-related markers, with synaptic deposit as the commonest PrP pattern (60.0%). …”
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