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7181
Assessment of line differentiation in the Thoroughbred horse breed using DNA microsatellite loci
Published 2019-08-01“…The data indicate genetic differentiation of lines of TB at the STR markers and confirm the effectiveness of the system of linear breeding for the maintenance of interbreed biodiversity.…”
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7182
Confronting the anxiety of Generation Z: electroacupuncture therapy regulates oxidative stress and microglia activity in amygdala-basolateral of socially isolated mice
Published 2025-02-01“…Additionally, biochemical analyses and immunofluorescence imaging were performed to assess the expression of NADPH oxidase 2 (NOX2), microglial activation markers, and levels of oxidative stress.ResultsOur findings reveal that EA treatment significantly mitigates anxiety-like behaviors in mice, correlating with a reduction in NOX2 expression within BLA microglia and decreased levels of reactive oxygen species (ROS). …”
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7183
Seasonal investigation of ultrafine-particle organic composition in an eastern Amazonian rainforest
Published 2025-01-01“…We present chemical evidence that indicates that biological-spore fragmentation impacted ultrafine-particle composition during the late wet season (JUN), while chemical markers for biomass burning and secondary chemistry peaked during the dry season (SEP and DEC). …”
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7184
Performance of the Illumina GGP Bovine 100K SNP array for buffalo populations genotyping in Colombia
Published 2023-11-01“…By extracting segregating SNPs in HD770K from the GGP-HD150K and GGP-LD30K chips, we identified 15,169 and 3,311 markers, respectively. Analysis using the GGP Bovine 100K revealed 5,995 segregating SNPs, of which 42.01% had Ho<=0.5. …”
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7185
Therapeutic Effects of the Combination of Alpha-Lipoic Acid (ALA) and Coenzyme Q10 (CoQ10) on Cisplatin-Induced Nephrotoxicity
Published 2020-01-01“…Renal functions, tissue antioxidant activity, and inflammatory markers (tumor necrosis factor, TNF) were estimated along with histopathological study. …”
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7186
Inheritance of effective juvenile leaf rust resistance in six accessions of Aegilops speltoides Tausch
Published 2019-02-01“…Before the introgression of the newly identified gene, it is necessary to study its identity to Lr47 using the phytopathological test; the use of molecular markers for this purpose is little informative.…”
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7187
Prognostic Value of STMN1 Expression in Non-small Cell Lung Cancer: A Meta-analysis
Published 2024-11-01“…Through meta-analysis, this study aimed to investigate the predictive value of the expression level of STMN1 for the prognosis of lung cancer and screen for tumor markers with high sensitivity and specificity to optimize the whole-process management of lung cancer patients. …”
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7188
Therapeutic Potential of Agmatine in Essential Tremor Through Regulation of Lingo‐1 and Inflammatory Pathways
Published 2025-01-01“…This study aimed to investigate whether agmatine, a biogenic amine neuromodulator attenuates tremors and modulates the expression of Lingo‐1 and proinflammatory markers in a rodent model of ET. Methods Tremor was induced in male Swiss Webster mice through intraperitoneal injections of harmaline (10 mg/kg) on Days 1, 3, and 5 of the study. …”
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7189
Adamantane Resistance in Seasonal Human Influenza A Viruses from Calgary, Alberta (January 2007 to August 2008)
Published 2010-01-01“…It is, thus, important to continue to monitor seasonal influenza A viruses for antiviral resistance markers to ensure optimal prophylaxis and treatment.…”
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7190
Study of the expression of oncoprotein p53, EGFR in colorectal carcinomas with different proliferative activity
Published 2023-04-01“…The aim of the study was to evaluate the prognostic significance of the expression of p53 and EGFR markers depending on the clinical, morphological characteristics and proliferative activity of colorectal carcinomas. …”
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7191
Non-alcoholic fatty liver disease: comparative assessment of diagnostic and treatment approaches in the Russian Federation and People’s Republic of China
Published 2018-08-01“…Liver biopsy is carried out at contradictory data of liver elastometry and serological fibrosis markers. Treatment of NAFLD should integrate the range of measures including correction of patients dietic habits and physical activity up to pharmacological treatment. …”
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7192
Impact of different pathogen classes on the serum N-glycome in septic shock
Published 2025-01-01“…Clinicians lack effective markers to rapidly diagnose sepsis and identify the underlying pathogen infection particularly for patients with candidaemia or cases of culture-negative sepsis where culture-based diagnostics are inadequate. …”
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7193
Protocol for a multicentre, prospective cohort study of clinical, proteomic and genomic patterns associated with osteoporosis to develop a multidimensional fracture assessment tool...
Published 2020-09-01“…The final aim is to develop a fracture risk assessment model, which would include clinical risk factors, biochemical markers of bone turnover, as well as specific genomic factors. …”
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7194
Multicentre Harmonisation of a Six-Colour Flow Cytometry Panel for Naïve/Memory T Cell Immunomonitoring
Published 2020-01-01“…Our experimental and analytical working process proved to be suitable for the harmonisation of FCM assays in a multicentre setting, where high-quality data are required to evaluate potential immunological markers, which may contribute to select better therapeutic options.…”
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7195
Construction and validation of a predictive model for the risk of prolonged preoperative waiting time in patients with intertrochanteric fractures
Published 2025-01-01“…The model’s performance was subsequently validated.ResultsThe predictive model developed from 728 patients in the training cohort, identified key predictors, including age, sex, lower extremity deep vein thrombosis, injury location, and biochemical markers. The model demonstrated strong discriminative ability, with an area under the receiver operating characteristic curve of 0.749 (95% confidence interval: 0.621–0.801) for the training set, and 0.745 in the validation set. …”
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7196
Investigating heterogeneity across autism, ADHD, and typical development using measures of cortical thickness, surface area, cortical/subcortical volume, and structural covariance
Published 2023-09-01“…IntroductionAttention-deficit/hyperactivity disorder (ADHD) and autism are multi-faceted neurodevelopmental conditions with limited biological markers. The clinical diagnoses of autism and ADHD are based on behavioural assessments and may not predict long-term outcomes or response to interventions and supports. …”
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7197
Vimentin as a contributing factor in SARS-CoV-2-induced orchitis on postmortem testicular autopsy of COVID-19 cases: A case-control study
Published 2025-01-01“…Additionally, gene expression analysis revealed increased expression of vimentin and decreased expression of the proliferation markers Ki67 and proliferating cell nuclear antigen, suggesting that SARS-CoV-2 may disrupt spermatogenesis through immune responses and the arrest of cell proliferation. …”
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7198
IGF-1 impacts neocortical interneuron connectivity in epileptic spasm generation and resolution
Published 2025-01-01“…In epileptic rats, expression of these three interneuron markers were reduced in the neocortex. IGF-1 expression was also reduced, but surprisingly this loss was confined to interneurons. …”
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7199
Tanshinone IIA Sodium Sulfonate Attenuates LPS-Induced Intestinal Injury in Mice
Published 2018-01-01“…In addition, expressions of autophagy markers (microtubule-associated light chain 3 (LC3) and Beclin-1) were detected by western blot and RT-PCR. …”
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7200
Evaluation of the cardiotoxicity of Echinochrome A using human induced pluripotent stem cell-derived cardiac organoids
Published 2025-01-01“…The hCOs, characterized by expression of key cardiac markers (cTnT) and functional ion channels (Cav1.2, Nav1.5, hERG), exhibited structural and electrophysiological properties reflective of human cardiac physiology. …”
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