Diversification outbreaks and dynamics of Asian leaf-litter frogs, genus Leptobrachella (Anura, Megophryidae), with the description of a new species from Guizhou Province, China by Tao Luo, Zi-Fa Zhao, Zhong-Lian Wang, Chang-Ting Lan, Ming-Yuan Xiao, Huai-Qing Deng, Ning Xiao, Jiang Zhou

“…This study highlights how biogeographic meta-analyses can be utilised to estimate diversification history in taxa lacking sufficient molecular markers to quantify the impact of orogeny and climatic shifts on diversification processes. …”
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Knowledge and motivations of researchers publishing in presumed predatory journals: a survey by David Moher, Agnes Grudniewicz, Kelly D Cobey, Manoj M Lalu, Danielle B Rice, Hana Raffoul

“…Objectives To develop effective interventions to prevent publishing in presumed predatory journals (ie, journals that display deceptive characteristics, markers or data that cannot be verified), it is helpful to understand the motivations and experiences of those who have published in these journals.Design An online survey delivered to two sets of corresponding authors containing demographic information, and questions about researchers' perceptions of publishing in the presumed predatory journal, type of article processing fees paid and the quality of peer review received. …”
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Serum levels of interleukin-6 type cytokines and soluble interleukin-6 receptor in patients with rheumatoid arthritis by T. Robak, A. Gladalska, H. Stepień, E. Robak

“…In conclusion, an increase in the serum levels of IL-6 and sIL-6R, but not LIF and CNTF concentrations, may be useful markers for RA activity.…”
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Lung Function Abnormalities in Sickle Cell Anaemia by Yvonne A. Dei-Adomakoh, Jane S. Afriyie-Mensah, Audrey Forson, Martin Adadey, Thomas A. Ndanu, Joseph K. Acquaye

“…Lung function abnormalities, particularly restrictive defects, are prevalent in Hb-SS patients but showed no significant association with recognized markers of disease severity.…”
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Image-Driven Hybrid Structural Analysis Based on Continuum Point Cloud Method with Boundary Capturing Technique by Kyung-Wan Seo, Junwon Park, Sang I. Park, Jeong-Hoon Song, Young-Cheol Yoon

“…The proposed technique effectively circumvents the inherent limitations of traditional monitoring methods resulting from the reliance on physical gauges or target markers so that a robust and non-contact solution for remote structural health monitoring in real-scale infrastructures can be provided, even in unfavorable experimental environments.…”
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Effect of <i>Cnidoscolus aconitifolius</i> (Family Euphorbiaceae) Aqueous Leaf Extract on Some Antioxidant Enzymes and Haematological Parameters of High Fat Diet and Streptozotocin... by EA Obichi, CC Monago, DC Belonwu

“…Our findings suggest that CA exhibited reversal effects on these selected oxidative and haematologic markers in rats which were previously damaged by HFD and STZ.…”
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Associations among immunophenotype, plasma metabolites, and benign prostatic hyperplasia: a mediation Mendelian randomization study by FAN Jiuming, ZHAO Yiqiao, JIA Haichang, WANG Tiankun, HAN Yutong, QIN Zihao, CHEN Ping, ZENG Xiantao

“…In the MR analysis of blood metabolites and BPH, IVW results identified 17 blood metabolite markers with significant causal associations with BPH. …”
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Cohort profile: Health in Central Denmark (HICD) cohort - a register-based questionnaire survey on diabetes and related complications in the Central Denmark Region by Annelli Sandbæk, Else-Marie Dalsgaard, Kasper Norman, Lasse Bjerg, Anders Aasted Isaksen

“…In addition to questionnaire data, the cohort is linked to nationwide registries that provide extensive data on hospital diagnoses and procedures, medication use and socioeconomic status decades before enrolment while laboratory registries has provided repeated measures of biochemical markers, for example, lipids, albuminuria and glycated haemoglobin up to 10 years before enrolment.Future plans The HICD will serve as an extensive resource for studies on patient-related information and inequality in type 1 diabetes and type 2 diabetes. …”
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Study of the immune state in different variants of anesthetic support for total laryngectomy by Yu.Yu. Kobelyatskyi, I.O. Shkitak

“…Patients were evenly and comparably divided into 4 research groups (n=25) based on the main clinical and age-sex characteristics (p>0.05) depending on the use of adjuvant components of multimodal anesthesia: in the group 1 they were not used, only opioid analgesics, in group II – lidocaine was used, in group III – dexmedetomidine, and in group IV – both lidocaine and dexmedetomidine. Studies of markers of the immune state (leucoformula, IL-2 and TNF-α) were carried out on the 1st, 2nd, 5th and 7th days after surgery. …”
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Evaluation of IL-29 in Euthyroid Patients with Graves’ Orbitopathy: A Preliminary Study by Bogusz Falkowski, Ewelina Szczepanek-Parulska, Nadia Sawicka-Gutaj, Aleksandra Krygier, Marek Ruchala

“…The following parameters were evaluated in every participant: thyroid-related hormones and autoantibodies and inflammatory markers (white blood cells, hsCRP). ELISA assay was applied to measure the concentration of IL-29. …”
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Feasibility, safety and tolerability of estrogen and/or probiotics for improving vaginal health in Canadian African, Caribbean, and Black women: A pilot phase 1 clinical trial. by Biban Gill, Jocelyn M Wessels, Christina L Hayes, Jenna Ratcliffe, Junic Wokuri, Elizabeth Ball, Gregor Reid, Rupert Kaul, Jesleen Rana, Muna Alkhaifi, Wangari Tharao, Fiona Smaill, Charu Kaushic

“…In addition, a panel of safety blood markers measured pre- and post-intervention confirmed no clinically significant changes in blood chemistry or blood cell count.…”
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Oral Cancer Stem Cell-Derived Small Extracellular Vesicles Promote M2 Macrophage Polarization and Suppress CD4+ T-Cell Activity by Transferring UCA1 and Targeting LAMC2 by Lan Wu, Sai Ye, Yilin Yao, Chenping Zhang, Wei Liu

“…The results showed that sEVs derived from CD133+CD44+ OSCC cells promoted M2 polarization of macrophages by detecting several M2 macrophage markers (CD163, IL-10, Arg-1, and CD206+CD11b+). Mechanistically, we revealed that the lncRNA UCA1, by binding to miR-134, modulated the PI3K/AKT pathway in macrophages via targeting LAMC2. …”
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Association between dietary mineral intake and new onset diabetes/pre-diabetes after chronic pancreatitis by Bingqing Li, Shan Guo, Wenlu Zong, Yuning Chu, Qi Zhang, Xiaoyan Yin, Tao Mao, Xiaoyu Li

“…The differences in mineral intake between the groups were compared, and the relationship between mineral intake and key glucose metabolism markers, including fasting plasma glucose (FPG), glycated hemoglobin (HbA1c), and fasting insulin, was analyzed using regression models.ResultsCompared with normal glycaemic status after chronic pancreatitis, the intake of iron and phosphorus in patients with new diabetes/pre-diabetes after chronic pancreatitis (NODCP) has changed significantly. …”
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Somatic Mitochondrial DNA Point Mutations Used as Biomarkers to Demonstrate Genomic Heterogeneity in Primary Prostate Cancer by Christian Arstad, Kristin Taskén, Paulo Refinetti, Ulrika Axcrona, Karl-Erik Giercksky, Per Olaf Ekstrøm

“…Thus, mitochondrial DNA mutations may be used as tumor cell markers. By the use of laser capture microdissection coupled with assays for mitochondrial point mutation detection, mtDNA mutations were used to trace mutated cells at a histological level. …”
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Prediction of Immune Infiltration Diagnostic Gene Biomarkers in Kawasaki Disease by Hongjun Ba, Yao Wang, Lili Zhang, Huishen Wang, Zhan-Peng Huang, Youzhen Qin

“…Candidate biological markers were determined utilizing the support vector machine recursive feature elimination and the least absolute shrinkage and selection operator regression model analysis. …”
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The Effect of Mesenchymal Stem Cell-Derived Exosomes and miR17-5p Inhibitor on Multicellular Liver Fibrosis Microtissues by Farnaz Sani, Mina Soufi Zomorrod, Negar Azarpira, Masoud Soleimani

“…Furthermore, EXO + anti-miR had the best effects on boosting the fibrotic markers. Therefore, we propose this novel MLM model to understand fibrosis mechanisms better and develop new drugs.…”
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Distinct roles of Constitutive Photomorphogenesis Protein 1 homolog (COP1) in human hepatocyte models by Sébastien Soubeyrand, Paulina Lau, Ruth McPherson, Ruth McPherson

“…In HepG2 and primary hepatocytes but not in HuH-7 cells, COP1 suppression reduced the expression of important hepatic regulators and markers. COP1 downregulation reduced hepatic nuclear factor-4 alpha (HNF4A) abundance and function, as assessed by a lower abundance of key HNF4A targets, reduced APOB secretion, and reporter assays. …”
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Human Immune System Increases Breast Cancer-Induced Osteoblastic Bone Growth in a Humanized Mouse Model without Affecting Normal Bone by Tiina E. Kähkönen, Mari I. Suominen, Jenni H. E. Mäki-Jouppila, Jussi M. Halleen, Azusa Tanaka, Michael Seiler, Jenni Bernoulli

“…Tumor-infiltrating lymphocytes (TILs) and the expression of immune checkpoint markers were analyzed by immunohistochemistry. Bone phenotyping showed no differences in bone architecture or volume of the healthy bones in huNOG and NOG mice, but the bone marrow fat was absent in huNOG mice. …”
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Predictive value of creatinine-cystatin C ratio for mortality and technique failure in anuric peritoneal dialysis patients by Zhihong Zhang, Tingting Zhou, Man Zhang, Shuiqin Cheng

“…Objectives Both serum creatinine and cystatin C serve as dependable markers of renal function and have demonstrated a correlation with clinical outcomes in diverse conditions, particularly through the ratio of creatinine to cystatin C (Cr/CysC). …”
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Immune-mediated mechanisms in acute osteofascial compartment syndrome: insights from multi-omics analysis by Qinzhen Lu, He Ling, Yonghui Lao, Junjie Liu, Wei Su, Zhao Huang

“…Presently, clinical diagnostics lack effective biological markers, and patients face a grim prognosis, experiencing muscle contractures, necrosis, amputations, renal failure, and even mortality. …”
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