Administration of a Next-Generation Probiotic Escherichia coli Nissle 1917-GLP-1 Alleviates Diabetes in Mice With Type 1 and Type 2 Diabetes by Jie Luo, Yilin Fang, Zhanghua Qi, Fengyang Cui, Hong Hu, Shengjie Li, Tingtao Chen, Hongyan Zhang

“…Furthermore, it exhibited a protective influence on the structural integrity of islet β-cells; downregulated the expressions of key inflammatory markers such as TLR-4, p-NF-κB/NF-κB, and Bax/Bcl-2; promoted the insulin secretion; and reinstated the perturbed diversity of microbial species to a normal state. …”
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Genotypes of Polymorphic Loci of BDNF and COMT Genes as Factors of Individual Differences in Coping Intelligence by E.V. Volkova, I.O. Kuvaeva, A.V. Varlamov, N.E. Volkova, D.A. Dokuchaev

“…No differences were found in relation to other coping measures, which requires the use of a wider range of genetic markers to describe individual differences in the manifestation of coping intelligence.…”
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Postoperative Pulmonary Hemodynamics and Systemic Inflammatory Response in Pediatric Patients Undergoing Surgery for Congenital Heart Defects by Maria Francilene S. Souza, Juliano G. Penha, Nair Y. Maeda, Filomena R. B. G. Galas, Kelly C. O. Abud, Eloisa S. Carvalho, Ana Maria Thomaz, Claudia R. P. Castro, Juliana Pereira, Antonio Augusto Lopes

“…For the entire cohort, circulating levels of 15 inflammatory markers changed after surgery. Compared with patients with PAP/SAPIPO≤0.40 (n=22), those above this level (n=18) had increased pre- and postoperative serum levels of granulocyte colony-stimulating factor (p=0.040), interleukin-1 receptor antagonist (p=0.020), interleukin-6 (p=0.003), and interleukin-21 (p=0.047) (panel for 36 human cytokines) and increased mean platelet volume (p=0.018). …”
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Sudden cardiac death after acute myocarditis with arrhythmic presentation: hunting for risk predictors − a systematic review and meta-analysis by Massimo Imazio, Valentino Collini, Maria Lucia Narducci, Federico Ballacci, Federica Giordano

“…Risk stratification for SCD during follow-up should be individualised, and monomorphic VA at presentation or a reduced LVEF may be markers of poor prognosis. In these cases, an ICD implantation may be cautious pending further dedicated studies.…”
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Abrupt onset or exacerbation of anorexia nervosa following recent infections: a mini-review and a case report with an atypical manifestation of PANS by Lavalle Raffaele, Tournour Cristina, Rubano Serena, Delsedime Nadia, Panero Matteo, Abbate-Daga Giovanni

“…Some cases improved with antibiotics or standard psychiatric treatments, although age, symptom severity, and diagnostic markers like D8/17 varied across studies. Data on treatment follow-up also varied. …”
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Distinct Redox Signalling following Macrophage Activation Influences Profibrotic Activity by Caitlin V. Lewis, Antony Vinh, Henry Diep, Chrishan S. Samuel, Grant R. Drummond, Barbara K. Kemp-Harper

“…Human primary and THP-1 macrophages were treated with IFN-γ+LPS or IL-4-activating stimuli, and mRNA expression of established M1 (CXCL11, CCR7, IL-1β) and M2 (MRC-1, CCL18, CCL22) markers was used to confirm activation. Superoxide generation was assessed by L-012-enhanced chemiluminescence and was increased in both M(IFN-γ+LPS) and M(IL-4) macrophages, as compared to unpolarised macrophages (MΦ). …”
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Sub-toxic cisplatin concentrations induce extensive chromosomal, nuclear and nucleolar abnormalities associated with high malignancy before acquired resistance develops: Implicatio... by John G Delinassios, Robert M Hoffman, George Koumakis, Dimitrios Palitskaris, Kyriaki-Nefelli Poulatsidou, George J Delinasios

“…Abnormal chromosome segregation, heightened aneuploidy (81-140 chromosomes), polyploidy, double minutes, dicentrics, chromatid exchanges, chromatid separations, pulverization, and chromosome markers were prominently noted. These abnormalities were intensified in cells pre-sensitized to 0.02 or 0.08 μg/ml cisplatin for seven days, then exposed to 0.03 or 0.1 μg/ml cisplatin for 24 hours, and finally cultured in cisplatin-free medium for 24 hours before chromosome analysis.…”
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Effects of Aerobic Exercise on Leukocyte-Mediated Liver Destruction in a Rat Model of Metabolic Syndrome by Fatmanur Er, Leyla Çimen, Ceren Suveren, Canan Yılmaz, Nurten Türközkan

“…Objective: In this study, the levels of malondialdehyde (MDA), myeloperoxidase (MPO), and 3-nitrotyrosine (3-NT), which are known as oxidative/nitrosative stress markers, were investigated in the liver tissues of rats with metabolic syndrome model induced by a high fructose diet, and the possible protective effects of aerobic exercise in fructose-fed rats were determined. …”
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Hepatitis B virus hijacks MRE11-RAD50-NBS1 complex to form its minichromosome. by Kaitao Zhao, Jingjing Wang, Zichen Wang, Mengfei Wang, Chen Li, Zaichao Xu, Qiong Zhan, Fangteng Guo, Xiaoming Cheng, Yuchen Xia

“…Transiently or stably knockdown of MRE11, RAD50 or NBS1 in hepatocytes before HBV infection significantly decreased viral markers, including cccDNA, while reconstitution reversed the effect. …”
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Adoption of the Polish Bariatric and Metabolic Surgery Care Standards: a nationwide survey by Mateusz J. Świerz, Karolina Majdak, Andrzej Budzyński, Wiesław Tarnowski, Piotr Major, Małgorzata M. Bala

“…The areas with compliance below 80% included availability of adapted radiology facilities, constant availability of emergency radiology diagnostics, screening for metabolic markers, assessment of obstructive sleep apnea risk, obtaining patient declaration of abstaining from smoking, providing dates for at least 1 dietary consultation upon discharge, requiring at least 2 consultations with an experienced dietician, and employing a surgeon with bariatric certificate of excellence. …”
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Clinical presentations and outcomes of celiac disease in children and adolescents at a tertiary care center in Lebanon by Dana Andari, Rima Hanna-Wakim, Sarah Khafaja, Nadine Yazbeck

“…The aim of this 10-year-retrospective study was to describe the common clinical presentations, diagnostic modalities, and the effect of the gluten-free- diet (GFD) on the growth of children and adolescents with celiac disease.MethodsThis was a retrospective chart review of subjects aged 6 months to 18 years who visited the Pediatric Gastroenterology clinic at the American University of Beirut Medical Center (AUBMC) between January 1, 2013, and June 30, 2023, and who were diagnosed with celiac disease based on serological markers and/or changes on histology of the small intestinal mucosal biopsies for those who underwent upper endoscopy, or HLA typing expressing the HLA-DQ2 or DQ8 gene for few subjects.ResultsThe study included 90 patients with celiac disease, of whom 64 were newly diagnosed during the study period. …”
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A Comprehensive Comparison of Clinical Presentation and Outcomes of Kidney Transplant Recipients with COVID-19 during Wave 1 versus Wave 2 at a Tertiary Care Center, India by Sanjiv Jasuja, Gaurav Sagar, Anupam Bahl, Neharita Jasuja, Rajesh Chawla, Avdhesh Bansal, Manjit. S. Kanwar, Sudha Kansal, Nikhil Modi, Athar P. Ansari, Viny Kantroo, Purnima Dhar, Chitra Chatterjee, Nitin Ghonge, Samir Tawakley, Shalini Verma

“…Both wave risk factors for mortality included older age, severe disease, ICU/ventilator requirements, acute kidney injury (AKI) needing dialysis, Chest Computerized Tomographic (CT) scan abnormalities, and higher levels of inflammatory markers particularly D-dimer and interleukin-6 levels. …”
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Progress in Treatment of Temporomandibular Joint Disorder by Wei YANG, Minghua XIE, Yu CAI, Zhuoming CHEN

“…The clinical manifestations are pain in the joint area or master muscle. There are joints or murmurs during joint opening, joint movement posture, rang of motion (ROM), opening type and other abnormalities. …”
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Effects of prophylactic antibiotic administration and antibiotic timing on culture results and clinical outcomes of paediatric musculoskeletal infection: a protocol for a randomise... by Chao You, Yibiao Zhou, Zhiyong Liu, Chao Deng, Yongjie Xia, Dechao Wu, Liangfu Xie, Bing E, Jingming Han

“…In addition, the disease-related markers including white blood cell count, C reactive protein, erythrocyte sedimentation rate, vital signs as well as the length of hospital stay will be measured or recorded accordingly. …”
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Electrochemical properties of hydroxyapatite immobilization material for potential cytosensor fabrication by Dennis Adusei, Bernard O. Asimeng, Francis D. Krampa, Elvis K. Tiburu

“…Conclusions: The unique current and impedance differences among the cells could serve as potential markers for rapid cell detection.…”
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Effect of <i>Cnidoscolus aconitifolius</i> (Family Euphorbiaceae) Aqueous Leaf Extract on Some Antioxidant Enzymes and Haematological Parameters of High Fat Diet and Streptozotocin... by EA Obichi, CC Monago, DC Belonwu

“…Our findings suggest that CA exhibited reversal effects on these selected oxidative and haematologic markers in rats which were previously damaged by HFD and STZ.…”
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A model for predicting acute heart failure in patients with acute myocardial infarction by taking into account energy and adipokine metabolism indicators by M.Yu. Koteliukh

“…Currently, adropin, irisin, fatty acid binding protein 4 (FABP 4) and C1q/TNF-binding protein 3 (CTRP 3) are considered to be valid markers of energy homeostasis and the adipokine system in AMI patients. …”
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Granulomatosis with Polyangiitis in Adolescence: Two Distinct Presentations by Rafael Figueiredo, Inês Pires Duro, António Marinho, Conceição Mota, Margarida Guedes, Carla Zilhão

“…In a twelve-year-old female with inflammatory signs of the limbs, investigation showed myositis of the thigh and tenosynovitis of the wrist, normocytic normochromic anemia (Hg 9.4 g/dL), mild elevation of inflammatory markers, and high creatine kinase. During hospitalization, she presented an extensive alveolar hemorrhage associated with severe anemia and positive C-ANCA and anti-PR3. …”
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The AMPK–mTOR Pathway Is Inhibited by Chaihu Shugan Powder, Which Relieves Nonalcoholic Steatohepatitis by Suppressing Autophagic Ferroptosis by Zheng Liang, Dajin Pi, Jianwei Zhen, Haizhen Yan, Chuiyang Zheng, July Liang Chen, Wen Fan, Qingliang Song, Jinyue Pan, Dongdong Liu, Maoxing Pan, Qinhe Yang, Yupei Zhang

“…The liver protein levels of Adenosine monophosphate-activated protein kinase–mammalian target of rapamycin (AMPK–mTOR)-mediated autophagy and ferroptosis markers, such as p-AMPKα/AMPKα, p-mTOR/mTOR, Beclin-1, microtubule associated protein 1 light chain 3 gamma (LC3), p62 (sequestosome 1 [SQSTM1/p62]), Kelch-like ECH-associated protein 1 (KEAP1), nuclear factor erythroid 2-related factor 2 (Nrf-2), ferritin heavy chain 1 (FTH1), and glutathione peroxidase 4 (GPX4), were restored by CSP. …”
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Relationship between the Sorghum's Physicochemical Attributes and the Flavor Components of Qing Stubble Daqu Baijiu by Linming SHI, Yanhong DU, Jianguang NIE, Hao TAN, Simai LI, Tingting LI

“…Utilizing gas chromatography, this research analyzed the flavor compound profiles in sorghum variants 'JINZA 22' 'Northeast sorghum' and 'American sorghum'. Differential markers in Baijiu samples were identified through partial least squares discriminant analysis (PLS-DA). …”
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