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6881
Genotypic variability in stress responses of Sorghum bicolor under drought and salinity conditions
Published 2025-01-01“…CRS-01 showed moderate resilience with the highest Na/K ratio and notable photosynthesis rate and relative water content, but was less consistent in biochemical markers under stress. Samsorg-42 demonstrated resilience under specific conditions but was generally less robust than Samsorg-17 across most indicators. …”
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6882
The Long Noncoding RNA Gm9866/Nuclear Factor-κB Axis Promotes Macrophage Polarization
Published 2023-01-01“…Real-time polymerase chain reaction analysis showed that overexpression of long noncoding RNA Gm9866 in RAW264.7 cells further promoted the expression of M2 markers MRC1 (macrophage mannose receptor 1) and MRC2 (macrophage mannose receptor 2). …”
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6883
Perilipin2-dependent lipid droplets accumulation promotes metastasis of oral squamous cell carcinoma via epithelial-mesenchymal transition
Published 2025-01-01“…Possible mechanisms of these biological effects were clarified by detecting the levels of epithelial-mesenchymal transition (EMT) markers and phosphatidylinositol 3-kinase (PI3K) pathway proteins as well as conducting various bioinformatics analyses. …”
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6884
Correlations of inflammatory processes caused by cerebral stroke with the outcome of the disease
Published 2023-10-01“…Elevated inflammatory markers and other prognostic factors are directly associated with higher rates of in-hospital complications such as pneumonia, urinary tract infection, and unfavorable stroke outcomes. …”
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6885
Exploring Inflammatory Changes in the Peripheral Blood of Type 2 Diabetes Mellitus in China
Published 2025-02-01“…This study aimed to thoroughly investigate the fluctuation of inflammatory markers in the peripheral blood of patients with T2DM, which are rarely reported.Methods: Peripheral blood samples from patients with T2DM and healthy individuals, as well as their clinical information, were collected at the Second Affiliated Hospital of Soochow University. …”
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6886
sCD40L Is Increased and Associated with the Risk of Gestational Diabetes Mellitus in Pregnant Women with Isolated TPOAb Positivity
Published 2022-01-01“…Soluble CD40 ligand (sCD40L) and soluble interleukin-2 receptor (sCD25) are abnormally expressed in autoimmune diseases and are reliable markers of inflammation. The purpose of this study was to evaluate sCD40L and sCD25 in early pregnancy and investigate their correlation with GDM and TPOAb. …”
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6887
L’établissement rural du second âge du Fer (275 av. à 15/20 ap. J.-C.) des “ Allets ” (Épeigné-les-Bois, Indre-et-Loire) et du “ Marchais Rond ” (Saint-Georges-sur-Cher, Loir-et-Ch...
Published 2021-09-01“…As for the palynological study, it provides remarkable results on the chronological succession of the enclosures based on the environmental markers identified at the different stages of their filling.…”
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6888
Evaluation of Bacillus coagulans LMG S-31876 for immunomodulation and stress: a double-blind, placebo-controlled clinical trial
Published 2025-01-01“…Over the course of 8 weeks, an improvement in the immune status was observed, as indicated by the immune status questionnaire. Enzymatic markers exhibited a significant decline in predicting a positive response toward treatment. …”
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6889
Status of the Multidrug Resistance-1 Gene of Plasmodium falciparum in Four Malaria Epidemiological Strata, Two Decades after the Abolition of Chloroquine as First-Line Treatment fo...
Published 2023-01-01“…Four hundred P. falciparum monoinfected samples, 100 per study area, were amplified by nested PCR, and allele-specific restriction analysis of Pfmdr1 gene molecular markers was performed. Fragments were analyzed using a 3% ethidium bromide-stained agarose gel. …”
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6890
Pituitary adenoma: literature review and association with TAS2R16 (rs978739, rs1357949) gene polymorphisms
Published 2023-10-01“…Considering the influence of environmental factors and genetic alterations that affect the occurrence of PA, new genetic markers can be searched to detect this disease. One of the risk factors contributing to the development of PA and its aggressiveness is alcohol consumption. …”
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6891
Combination therapy of low-dose radiotherapy and immunotherapy in advanced metastatic nasopharyngeal carcinoma: a case report and literature review
Published 2025-01-01“…Conclusion The combination of chemotherapy and LDRT with aspirin and human granulocyte macrophage colony-stimulating factor improved the disease state of advanced NPC cancer, effectively reducing the level of tumor markers, enhanced the immune function without significant adverse reactions.…”
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6892
Dysregulation of Metabolic Peptides Precedes Hyperinsulinemia and Inflammation Following Exposure to Rotenone in Rats
Published 2025-01-01“…The potential implications of these findings are vast, given that monitoring these markers in the blood could not only provide a crucial tool for assessing the extent of exposure and its relevance to obesity and inflammation but could also open new avenues for future research and potential therapeutic strategies.…”
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6893
Decreased Gray Matter Volume in the Frontal Cortex of Migraine Patients with Associated Functional Connectivity Alterations: A VBM and rs-FC Study
Published 2022-01-01“…However, the pathophysiology and imaging markers specific for migraine pathologies are not well understood. …”
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6894
The problem of conservation of gene pools of domesticated animals
Published 2017-07-01“…Within breeds of the same species or within one species it is possible to spot the ancient or the most estranged from the “protogene pool” groups of animals and, thus, to use these data in the breeding strategy aimed at the preservation of animal forms close to the ancestral form. Using various DNA markers, methods of genomic and genetic breeding in nature conservation and genetic selection of domesticated species provides an opportunity to obtain data on the genetic potential (value, originality) of the breed, which is important for scientific justification of its preservation.…”
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6895
Endothelial injury is one of the risk factors for the progression of vascular calcification in patients receiving maintenance dialysis
Published 2025-12-01“…We also detected the markers of endothelial injury [E-selectin and soluble intercellular adhesion molecule-1 (sICAM-1)]. …”
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6896
Efficacy and Safety of Bicyclol Treatment for Non-Alcoholic Fatty Liver Disease: Results of a Cohort Study
Published 2018-09-01“…Bicyclol therapy in NAFLD is accompanied by positive dynamics of inflammation activity markers, insulin resistance and lipid spectrum, which suggests a positive dynamics of the stages of liver fibrosis and steatosis.…”
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6897
SequenceCraft: machine learning-based resource for exploratory analysis of RNA-cleaving deoxyribozymes
Published 2025-01-01“…In particular, DNAzymes able to cleave RNA sequences have a huge potential in gene therapy and sequence-specific analytic detection of disease markers. This activity is provided by catalytic cores able to perform site-specific hydrolysis of the phosphodiester bond of an RNA substrate. …”
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6898
The feasibility of using liver function indices and FibroScan in combination to predict the occurrence of anti-tuberculosis drug-induced liver injury in Patients with liver disease
Published 2025-01-01“…Results: Patients who developed DILI showed significantly higher levels of ALT, AST, total bilirubin, GGT, and LSM, with strong positive correlations between these markers and DILI occurrence. Logistic regression analysis revealed elevated ALT, AST, TBIL, and GGT were strongly associated with an increased likelihood of DILI. …”
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6899
Why is the New York Times Writing so Much about Alzheimer's Disease Therapies?
Published 2010-01-01“…The history of drug development for other diseases should encourage us to focus on patients in whom we can identify the genetic markers associated with familial ad. Then when we have an efficacious and very safe drug, we will be able to establish its efficacy on, most importantly, cognition, but also at the level of plaques. …”
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6900
Older People's Perceptions of Well-Being
Published 2025-01-01“…In the semantic group “emotions” in the structure of ideas about well-being in elderly people, emotions of greater intensity prevail over emotions of lesser intensity. Markers of negative emotions in the structure of ideas about well-being are absent.…”
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