Neuron-Specific Fluorescence Reporter-Based Live Cell Tracing for Transdifferentiation of Mesenchymal Stem Cells into Neurons by Chemical Compound by Do Won Hwang, Hyun Woo Kwon, Jaeho Jang, Hee Jung Jung, Kwang Rok Kim, Dong Soo Lee

“…Two days after NHPDQC treatment, MSCs showed neuron-like phenotype with neurite outgrowth and high expression of neuron-specific markers in more than 95% cells. The fluorescence signals increased in the cytoplasm of pTα1-DsRed2-transfected MSCs after NHPDQC treatment. …”
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Endothelial-Ercc1 DNA repair deficiency provokes blood-brain barrier dysfunction by Cathrin E. Hansen, Davide Vacondio, Lennart van der Molen, Annika A. Jüttner, Wing Ka Fung, Manon Karsten, Bert van het Hof, Ruud D. Fontijn, Gijs Kooij, Maarten E. Witte, Anton J. M. Roks, Helga E. de Vries, Inge Mulder, Nienke M. de Wit

“…In line, EC-KO mice showed more P21+ cells, augmented expression of angiogenic markers, and a concomitant increase in the number of brain ECs and pericytes. …”
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Potential value of novel multiparametric MRI radiomics for preoperative prediction of microsatellite instability and Ki-67 expression in endometrial cancer by Zhichao Wang, Yan Hu, Jun Cai, Jinyuan Xie, Chao Li, Xiandong Wu, Jingjing Li, Haifeng Luo, Chuchu He

“…The hybrid radiomics model (HMRadSum) was developed by extracting quantitative imaging features and deep learning features from multiparametric MRI using emerging attention mechanism. Tumor markers were subsequently predicted utilizing an XGBoost classifier. …”
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Effect of phototherapy on event-related potentials in patients with post-stroke depression through serum tetrahydrobiopterin level intervention: a clinical study by Bingchuan Xie, Zhenguo Wu, Zixuan Zhou, Wenting Lu, Lin Liu, Lizhuang Zhang

“…Additionally, inflammatory markers IL-6, TNF-α, and IL-1β were lower in the phototherapy group (P < 0.05). …”
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Rheopheresis in treatment of idiopathic sensorineural sudden hearing loss by Milan Kostal, Jakub Drsata, Milan Bláha, Miriam Lánská, Viktor Chrobok

“…Older age (p = 0.003), presence of vertigo (p = 0.006) and more profound initial hearing loss (p < 0.001) were identified as negative prognostic markers. Conclusion Rheopheresis can be used as a potentially effective and safe salvage therapy for patients with cortico-refractory SISHL.…”
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Rapamycin Improves Palmitate-Induced ER Stress/NF κ B Pathways Associated with Stimulating Autophagy in Adipocytes by Jiajing Yin, Liping Gu, Yufan Wang, Nengguang Fan, Yuhang Ma, Yongde Peng

“…Inhibiting autophagy with chloroquine (CQ) exacerbated these ER stress markers, indicating the role of autophagy in ameliorating ER stress. …”
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Effects of Dietary Addition of a Low-Pectin Apple Fibre Preparation on Rats by Fotschki Bartosz, Jurgoński Adam, Juśkiewicz Jerzy, Kołodziejczyk Krzysztof, Sójka Michał

“…The aim of this study was to scrutinise if the dietary addition of a low-pectin fibre preparation obtained from apple pomace, the by-product of apple concentrate processing, is able to favourably affect the gut metabolism, antioxidant status and blood bio-markers of the organism, as it takes place when apple fibre is present in the diet as an unprocessed ingredient. …”
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Effects of a flavonoid-enriched orange peel extract against type 2 diabetes in the obese ZDF rat model by Alexander Gosslau, Emmanuel Zachariah, Shiming Li, Chi-Tang Ho

“…Effects of an enriched orange peel extract (OPE) against type 2 diabetes (T2D) were analyzed in ZDF rats which were hyperglycemic, dyslipidemic and express pro-inflammatory markers. Glucose related parameters were lowered in the lean control and metformin group as compared to ZDF vehicle controls. …”
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Studies on banana for propagation, conservation and genome analysis by Susmita Shukla, Ritambhara Bhutani, Nibha Gupta, Shiv Kant Shukla, Taramla Raman, Mohamed A. El-Sheikh, Hosam O. Elansary, Ihab Mohamed Moussa

“…DNA barcoding using Internal Transcribed Spacer1 (ITS1) markers facilitated the molecular analysis and sequence alignment of these Musa species, which illustrated their genetic relationships. …”
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Combined effects of global DNA methylation, blood lead and total urinary arsenic levels on developmental delay in preschool children by Yuu-Hueih Hsu, Chih-Yin Wu, Hui-Ling Lee, Ru-Lan Hsieh, Ya-Li Huang, Horng-Sheng Shiue, Ying-Chin Lin, Mei-Chieh Chen, Yu-Mei Hsueh

“…Abstract DNA methylation is a critical step in brain development, 5-Methyl-2'-deoxycytidine (5mdC) is one of the global DNA methylation markers. Arsenic and lead exposures have been associated with neurotoxicity, which may be linked to epigenetic changes. …”
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Highly Proliferative Immortalized Human Dental Pulp Cells Retain the Odontogenic Phenotype when Combined with a Beta-Tricalcium Phosphate Scaffold and BMP2 by Xiangfen Li, Liu Wang, Qin Su, Ling Ye, Xuedong Zhou, Dongzhe Song, Dingming Huang

“…The immortalized human dental pulp cells (iHDPCs) acquired long-term proliferative activity and expressed most HDPC markers. The iHDPCs maintained multiple differentiation potential and could be induced to differentiate into chondrogenic, osteogenic, and adipogenic cells in vitro. …”
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AxonFinder: Automated segmentation of tumor innervating neuronal fibers by Kaoutar Ait-Ahmad, Cigdem Ak, Guillaume Thibault, Young Hwan Chang, Sebnem Ece Eksi

“…Our paper suggests the potential utility of neuronal markers in the prognostic assessment of prostate cancer in aiding the pathologist's assessment of tumor sections and advancing our understanding of neurosignaling in the tumor microenvironment.…”
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CXC chemokine receptor 7 ameliorates renal fibrosis by inhibiting β-catenin signaling and epithelial-to-mesenchymal transition in tubular epithelial cells by Ping Meng, Chunli Liu, Jingchun Li, Ping Fang, Bo Yang, Wei Sun, Yunfang Zhang

“…Using cultured HKC-8 cells, we found that CXCR7 significantly downregulated the expression of active β-catenin and fibrosis-related markers, including fibronectin, Collagen I, and α-SMA. …”
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The Imbalance of FOXP3/GATA3 in Regulatory T Cells from the Peripheral Blood of Asthmatic Patients by Tiantian Chen, Xiaoxia Hou, Yingmeng Ni, Wei Du, Huize Han, Youchao Yu, Guochao Shi

“…Proliferation-and function-associated markers of Treg cells along with the percentage of Treg cells producing some cytokine from asthmatics and healthy subjects were analyzed by flow cytometry. …”
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A model-based factorization method for scRNA data unveils bifurcating transcriptional modules underlying cell fate determination by Jun Ren, Ying Zhou, Yudi Hu, Jing Yang, Hongkun Fang, Xuejing Lyu, Jintao Guo, Xiaodong Shi, Qiyuan Li

“…In real datasets, MGPfactXMBD recovered the critical pathways and cell types in microglia development with experimentally valid regulons and markers. Furthermore, MGPfactXMBD discovered evolutionary trajectories of tumor-associated CD8+ T cells and yielded new subtypes of CD8+ T cells with gene expression signatures significantly predictive of the responses to immune checkpoint inhibitor in independent cohorts. …”
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RadBone: bone toxicity following pelvic radiotherapy – a prospective randomised controlled feasibility study evaluating a musculoskeletal health package in women with gynaecologica... by Janelle Yorke, Sarah O’Connell, Sally Taylor, Karen Johnson, Robert G Bristow, Martin Eden, Kate Haslett, John Moore, Rohit Kochhar, Victoria Chatzimavridou Grigoriadou, Lisa H Barraclough, Ivona Baricevic-Jones, Zoe Merchant, Thomas Westwood, Anthony David Whetton, Claire E Higham

“…Clinical effectiveness and bone turnover markers will be evaluated as secondary outcomes.Ethics and dissemination This study has been approved by the Greater Manchester East Research Ethics Committee (Reference: 20/NW/0410, November 2020). …”
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Lunar and Martian gravity alter immune cell interactions with endothelia in parabolic flight by Yu Du, Bing Han, Katharina Biere, Nathalie Abdelmalek, Xinyu Shu, Chaoyang Song, Guangyao Chen, Ning Li, Marina Tuschen, Huan Wu, Shujin Sun, Alexander Choukér, Mian Long, Dominique Moser

“…Expression levels of the adhesion markers Mac-1 on THP-1 cells as well as ICAM-1 on HUVECs were found elevated in lunar and Martian gravity, which was aggravated by TNF. …”
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Fish Gut Metabarcoding Detects Diets and Parasites Simultaneously by Dilli Prasad Rijal, Per Arneberg, Tanja Hanebrekke, Torild Johansen, Daniela Sint, Michael Traugott, Mette Skern‐Mauritzen, Jon‐Ivar Westgaard

“…Using one of the commercially exploited beaked redfish (Sebastes mentella) from the Barents Sea, our study aims to understand its diet composition and parasites. We used 12S and COI markers to analyze the stomach and intestine contents of uncleaned, water‐cleaned, and bleach‐cleaned fish samples to also trace how external contamination affects diet analysis of fishes. …”
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Maternal Fructose Intake Induces Insulin Resistance and Oxidative Stress in Male, but Not Female, Offspring by Lourdes Rodríguez, Paola Otero, María I. Panadero, Silvia Rodrigo, Juan J. Álvarez-Millán, Carlos Bocos

“…Interestingly, plasma AOPP and uricemia (oxidative stress markers) were augmented in male rats from fructose-fed mothers compared to the animals from control or glucose-fed mothers. …”
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Effect of Chromatin-Remodeling Agents in Hepatic Differentiation of Rat Bone Marrow-Derived Mesenchymal Stem Cells In Vitro and In Vivo by Danna Ye, Tong Li, Philip Heraud, Rangsun Parnpai

“…TSA enhanced the development of the hepatocyte shape, promoted the chronological expression of hepatocyte-specific markers, and improved hepatic functions. In contrast, treatment of rBM-MSCs with 20 μM 5-aza-dC alone or in combination with TSA was ineffective in improving hepatic differentiation in vitro. …”
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