From micro to macro, nanotechnology demystifies acute pancreatitis: a new generation of treatment options emerges by Wei Du, Xinyue Wang, Yuyan Zhou, Wencheng Wu, Haojie Huang, Zhendong Jin

“…In particular, the changes in inflammatory markers and therapeutic outcomes following the administration of nanomaterials are examined. …”
Get full text

Effects of ultra-processed foods on the liver: insights from gut microbiome and metabolomics studies in rats by Liping Shi, Zhuoyuan Li, Xiaojun Ma, Junru Wang, Yueping Wu, Yongbin Zhu, Yanrong Wang, Yue Yang, Minxiu Luo, Jiangping Li, Xian Sun, Xian Sun, Shulan He, Shulan He

“…Some serum biochemical indices, inflammatory factors, oxidative stress markers, hematoxylin–eosin (HE) staining of the liver, 16S ribosomal RNA (rRNA) and Liquid chromatography-mass spectrometry (LC–MS) of rat feces were detected.ResultsThe UPF diet-induced simple steatosis of the liver in rats without affecting the levels of IL-6, GSH, MDA, and SOD. …”
Get full text

Impaired Lymphocyte Profile in Schistosomiasis Patients with Periportal Fibrosis by Luciana Santos Cardoso, Andréia de Souza Rocha Barreto, Jamille Souza Fernandes, Ricardo Riccio Oliveira, Robson da Paixão de Souza, Edgar M. Carvalho, Maria Ilma Araujo

“…Peripheral blood mononuclear cells were obtained by the Ficcol-hypaque gradient and the frequency of T cells expressing the surface markers CD28, CD69, CD25, and CTLA-4 was determined by flow cytometry. …”
Get full text

Immunofluorescence for Detection of TOR Kinase Activity In Situ in Photosynthetic Organisms by Ana Lando, María De Marco, Andrea Cumino, Giselle Martínez-Noël

“…In addition, different ultrastructural cell markers can also be used, such as for nucleus and cell wall detection, allowing a detailed analysis of cell morphology. …”
Get full text

Safety evaluation of ethanol extract from Artocarpus altilis leaves as a herbal medicine candidate: Studies in acute and subchronic toxicity by Fitrya Fitrya, Elfita Elfita, Ferlinahayati, Salma Fayzah Septami, Umi Tsalsa Sabrina, Fatma Sri Wahyuni, Annisa Amriani, Rennie Puspa Novita

“…Mortality, variations in body weight, hematological and biochemical markers, organ index, and the histology of vital organs were all used to study toxic symptoms. …”
Get full text

Skin Autofluorescence Relates to Soluble Receptor for Advanced Glycation End-Products and Albuminuria in Diabetes Mellitus by J. Škrha, J. Šoupal, G. Loni Ekali, M. Prázný, M. Kalousová, J. Kvasnička, L. Landová, T. Zima, J. Škrha

“…The aim of this study was to compare skin autofluorescence caused by advanced glycation end-products (AGEs) with biochemical markers of endothelial dysfunction and soluble receptor for AGEs (sRAGE) in patients with diabetes. …”
Get full text

Standardization of Tragopogon graminifolius DC. Extract Based on Phenolic Compounds and Antioxidant Activity by Mohammad Hosein Farzaei, Mahnaz Khanavi, Ghazaleh Moghaddam, Farzaneh Dolatshahi, Roja Rahimi, Mohammad Reza Shams-Ardekani, Gholamreza Amin, Mannan Hajimahmoodi

“…Generally, phenolic compounds are one of the major constituents of TG and could be used as markers for standardization of dosage forms prepared from this plant. …”
Get full text

Continuous Genetic Assessment of the Impact of Hatchery Releases on Larimichthys crocea Stocks in China by Lina Wu, Lisheng Wu, Hungdu Lin, Min Liu, Shaoxiong Ding

“…In this study, we analyzed hatchery-released stocks (HRS), and wild-captured stocks in the semi-closed Sansha Bay (SBS, northern Fujian) and in the open waters of southern Fujian (SFS) over four consecutive years (2020–2023) using microsatellite markers. Our results reveal the significant genetic differentiation and distinct contribution rates between SBS and SFS, highlighting the region-specific impacts of restocking. …”
Get full text

Clinical pathological characteristics and prognosis of orbital myeloid sarcoma-a single center retrospective study with 14 Chinese patients by Tianyi Zhou, Jiaqi Guan, Huijing Ye, Huasheng Yang

“…Immunohistochemical analysis revealed that MPO (myeloperoxidase) and lysozyme were the most frequently expressed markers, followed by CD56, α1-antitrypsin (AACT), and CD34. …”
Get full text

Association of Maternal Age to Development and Progression of Retinopathy of Prematurity in Infants of Gestational Age under 33 Weeks by Atsuro Uchida, Masayuki Miwa, Hajime Shinoda, Takashi Koto, Norihiro Nagai, Hiroshi Mochimaru, Yohei Tomita, Mariko Sasaki, Kazushige Ikeda, Kazuo Tsubota, Yoko Ozawa

“…To find predictive and indicative markers of risk for development of retinopathy of prematurity (ROP) and its progression to the stage requiring laser treatment, in premature infants whose gestational age (GA) was under 33 weeks. …”
Get full text

Therapeutic Effect and Location of GFP-Labeled Placental Mesenchymal Stem Cells on Hepatic Fibrosis in Rats by Jiong Yu, Guangshu Hao, Dan Wang, Jingqi Liu, Xiaotian Dong, Yanni Sun, Qiaoling Pan, Yang Li, Xiaowei Shi, Lanjuan Li, Hongcui Cao

“…The expression levels of fibrotic markers, transforming growth factor β1 (TGF-β1) and α-smooth muscle actin (α-SMA), were assessed using real-time polymerase chain reaction. …”
Get full text

The Expression Level of mRNA, Protein, and DNA Methylation Status of FOSL2 of Uyghur in XinJiang in Type 2 Diabetes by Jun Li, Siyuan Li, Ying Hu, Guolei Cao, Siyao Wang, Partab Rai, Xiaoli Wang, Kan Sun

“…Methylation of CpG sites was found to inversely correlate with expression of other markers. Conclusions. Results show that a correlation between mRNA, protein, and DNA methylation of FOSL2 gene exists among T2DM patients from Uyghur. …”
Get full text

The impact of genetic polymorphisms of IL28B gene on the efficacy of antiviral therapy of the chronic hepatitis C by using the standard Interferon-<i>α</i> by A. V. Lapshin, M. V. Mayevskaya, V. T. Ivashkin, P. O. Bogomolov, I. G. Nikitin, O. O. Znoyko

“…The analysis of the efficacy of the treatment was conducted on the basis of the assessment of the normalization of the biochemical cytolysis markers during and after the treatment as well as the availability of the rapid, early and stable virology response.Results. …”
Get full text

Diagnostic and prognostic values of tsRNAs in lung cancer: a meta-analysis by Cheng Tang, Su-Xia Sun, Chao Gu, Chao-Juan Li, Jin Xu, Ke-Lei Su, Dan-Dan Zhou, Kuai Yu, Qing-Ling Xiao, Xiao-Li Chen

“…Diagnostic odds ratios (DORs) and areas under the receiver operating characteristic curve (AUCs) were used to evaluate the potential of tsRNAs as diagnostic markers for LC. Furthermore, hazard ratios (HRs) and 95% confidence intervals (95% CIs) were used to analyze association of tsRNAs with LC prognosis. …”
Get full text

Kurgans of the Sargat Culture in the Middle Irtysh River Basin: New Approaches in Estimation of Social Landscape by Maxim A. Grachev, Oksana Yu. Zimina, Nickolay V. Prikhodko, Svetlana V. Sharapova

“…“Princely kurgans” were accommodated to dominant heights of foremost river terrace what was decisive in landscape exploitation, i.e. new territory markers were erected and thus transformation of landscape into social sense occurred. …”
Get full text

Proteomic profiling identifies upregulation of aurora kinases causing resistance to taxane-type chemotherapy in triple negative breast cancer by Bohan Ning, Chang Liu, Ali Cem Kucukdagli, Jiuyi Zhang, Han Jing, Zhiqian Zhou, Yuwei Zhang, Ying Dong, Yunjia Chen, Hua Guo, Jia Xu

“…In summary, we revealed that Aurora Kinases upregulation after treatment with chemotherapy could confer chemotherapy resistance to TNBC cells, and AURKB could serve as preselection markers for stratifying patients’ response to neoadjuvant chemotherapy.…”
Get full text

18F-Fluorothymidine-Pet Imaging of Glioblastoma Multiforme: Effects of Radiation Therapy on Radiotracer Uptake and Molecular Biomarker Patterns by Sanjay Chandrasekaran, Andrew Hollander, Xiangsheng Xu, Joseph L. Benci, James J. Davis, Jay F. Dorsey, Gary Kao

“…Patterns of tumor PET imaging were then compared to immunohistochemistry and immunofluorescence for markers of proliferation (Ki-67), DNA damage and repair (γH2AX), hypoxia (HIF-1α), and angiogenesis (VEGF). …”
Get full text

Overall Survival of Elderly Patients Having Surgery for Colorectal Cancer Is Comparable to Younger Patients: Results from a South Asian Population by Pramodh Chitral Chandrasinghe, Dileepa Senajith Ediriweera, Thaaqib Nazar, Sumudu Kumarage, Janaki Hewavisenthi, Kemal Ismail Deen

“…Demographics, tumour characteristics, and serological markers were considered as independent factors. Multivariable analysis was done using the Cox proportional hazard model. …”
Get full text

Neurocognitive Deficits in Individuals at Ultra-High-Risk for Psychosis: An Overview of Systematic Reviews by Farnaz Asadiof, Mona Zamanpour, Ali Fawzi Al-Hussainy, Alhan Abd Al-Hassan Shalal, Mohammed Ubaid, Zinab Aluquaily, Seyed Hamidreza Hashemian

“…., PubMed, Scopus, and Google Scholar using predefined keywords related to predictive neurocognitive markers and ultra-high risk psychosis. By following the PRISMA procedure, we included all relevant systematic-reviews and meta-analyses in our data-synthesis. …”
Get full text

Atlantic mackerel population structure does not support genetically distinct spawning components [version 2; peer review: 1 approved, 2 approved with reservations] by Imanol Aguirre-Sarabia, Alice Manuzzi, Dorte Bekkevold, Natalia Díaz-Arce, Jessica Gomez-Garrido, Teunis Jansen, Marta Gut, Tyler S. Alioto, Sonia Sanchez-Maroño, Martin Castonguay, Naiara Rodriguez-Ezpeleta, Paula Álvarez

“…Methods Here, the genome of S. scombrus was sequenced and annotated, as an increasing number of population genetic studies have proven the relevance of reference genomes to investigate genomic markers/regions potentially linked to differences at finer scale. …”
Get full text