O Serogroup-Specific Touchdown-Multiplex Polymerase Chain Reaction for Detection and Identification of Vibrio cholerae O1, O139, and Non-O1/Non-O139 by Adisak Bhumiratana, Achiraya Siriphap, Nutsarin Khamsuwan, Jednipit Borthong, Kaknokrat Chonsin, Orasa Sutheinkul

“…A panel of molecular marker-based TMPCR method generates reproducible profiles of V. cholerae-specific (588 bp) amplicons derived from ompW gene encoding the outer membrane protein and serogroup-specific amplicons, 364 bp for the O1 and 256 bp for the O139, authentically copied from rfb genes responsible for the lipopolysaccharide biosynthesis. …”
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Identifying genetic susceptibility loci associated with human coronary artery disease. by Aqsa Zahid, Andleeb Batool, Abdul Wajid, Yurong Wu, Chun Liang, Muhammad Ajmal Khan, Amin Ullah, Kashif Iqbal Sahibzada, Hong Xue

“…This ultimately improving patient outcomes and guiding future research to highlight its significance as a potential diagnostic marker.…”
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Unveiling dynamic hepatocyte plasticity in HepaRG cells with a dual CYP reporter system. by Riku Asano, Yohei Iizaka, Makoto Kashima, Yojiro Anzai, Shinpei Yamaguchi, Masako Tada

“…These findings underscore the dynamic nature of HepaRG cells while cautioning against solely relying on CYP3 family gene expression as a marker of differentiation.…”
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Total antioxidant capacity status in non-obese adolescent females with PCOS: a cross-section study by Moushira Zaki, Safenaz Y. El Sherity, Mohamed Metkees, Sondos Salem, Tamer Elnahas, Ehab Salama, Mina Wassef Girgiss, Eman Refaat Youness

“…Aim The purpose of the present work was to estimate total antioxidant capacity (TAC) in non-obese adolescents and decide if the TAC could be a potential marker for the prediction and diagnosis of PCOS. Methods Serum samples were collected to assess the levels of follicle stimulant hormone (FSH), luteinizing hormone (LH), serum lipids, and serum total antioxidant capacity (TAC) in 50 non-obese patients with PCOS and 50 controls; correlation analysis was made between serum lipid, hormonal parameters, and TAC. …”
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Granzyme B PET imaging of immune-mediated tumor killing as a tool for understanding immunotherapy response by Thomas LaSalle, Emily E Austin, Grant Rigney, Eric Wehrenberg-Klee, Sarah Nesti, Benjamin Larimer, Umar Mahmood

“…Here, we used the quantitative measurement of granzyme B release as a direct and time-matched marker of immune cell activation in order to determine immune cell types and cytokines that correlate with effective checkpoint inhibitor therapy in both tumors and tumor-draining lymph nodes.Results Through PET imaging, we were able to successfully distinguish distinct microenvironments, based on tumor type, which influenced immune cell subpopulations and cytokine release. …”
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PIM2 inhibition promotes MCL1 dependency in plasma cells involving integrated stress response-driven NOXA expression by Marion Haas, Sabrina Cherfa, Léa Nguyen, Maxence Bourgoin, Gersende Caron, Elise Dessauge, Tony Marchand, Laurent Delpy, Patrick Auberger, Jérôme Moreaux, Arnaud Jacquel, Thierry Fest

“…Elevated PIM2 expression, a marker of various cancers, often correlates with disease aggressiveness. …”
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Isolation and Characterisation of Mesenchymal Stem Cells from Rat Bone Marrow and the Endosteal Niche: A Comparative Study by Norhayati Yusop, Paul Battersby, Amr Alraies, Alastair J. Sloan, Ryan Moseley, Rachel J. Waddington

“…CB-MSCs and BM-MSCs both expressed MSC (CD73/CD90/CD105); embryonic (Nanog) and osteogenic markers (Runx2, osteocalcin) but no hematopoietic markers (CD45). …”
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Effect of Dipeptidyl Peptidase-4 (DPP-4) Inhibition on Biomarkers of Kidney Injury and Vascular Calcification in Diabetic Kidney Disease: A Randomized Controlled Trial by Thananda Trakarnvanich, Bancha Satirapoj, Swangjit Suraamornkul, Thanit Chirananthavat, Anoma Sanpatchayapong, Torpong Claimon

“…The changes in the coronary calcium score (CAC score), cardio-ankle vascular index (CAVI), estimated glomerular filtration rate (eGFR), vascular calcification level, and tubular renal injury marker expression were evaluated at baseline and 6 months. …”
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The relationship between leptin and resistin levels and parameters of the ambulatory blood pressure monitoring in patients with type 2 diabetes and arterial hypertension. by A. M. Urbanovych

“…Instead, resistin levels in blood plasma can be considered as a prognostic marker of cardiovascular disease, including hypertension, in patients with type 2 diabetes.…”
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Monitoring terrestrial rewilding with environmental DNA metabarcoding: a systematic review of current trends and recommendations by Clare Cowgill, James D. J. Gilbert, Ian Convery, Lori Lawson Handley, Lori Lawson Handley

“…Metabarcoding did not consistently outperform other methods in terms of the number of vertebrate taxa detected, and this was likely influenced by choice of marker, sampling substrate and habitat.DiscussionOur findings indicate that metabarcoding, particularly of eDNA, has the potential to play a key role in the monitoring of terrestrial rewilding, but that further ground- truthing is needed to establish the most appropriate sampling and experimental pipelines for the target taxa and terrestrial system of interest.Systematic Review Registrationhttps://osf.io/38w9q/?…”
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Identification of circulating Tfh/Th subsets as a biomarker of developed hospital-acquired pneumonia by Yuan Peng, Tao Tao, Ni-Wen Yu, Chenyang Xu, Cheng Chen

“…Accordingly, the combination of Tfh/Th and PCT could serve as a more effective predictive marker for HAP deterioration and survival prediction. …”
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The Role of Prolactin as a Disease Activity Indicator in Some Rheumatic Diseases by Mohamed Ismail Abdelkarem, HM Fayed, Wael Abd El-Mohsen Abady, Eman Abulhagag Mohammed Mahmoud

“…Regular monitoring may be necessary because of the potential of PRL to function as a marker of disease activity. The therapeutic potential of dopamine agonists in autoimmune diseases warrants further investigation, as they have the potential to reduce flare-ups and organ involvement.…”
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Percutaneous closure of a traumatic ventricular septal defect: a case report and literature review by Camilo Andres Calderon-Miranda, Maria Juliana Reyes-Cardona, Gabriel Roberto Lopez-Mora, Fernando Andrés Guerrero-Pinedo, Jairo Sanchez-Blanco, Carlos Enrique Vesga-Reyes, Jorge Alexander Zambrano-Franco, Pastor Olaya

“…During treatment for a surgical site infection a new-onset pansystolic murmur was found: A transthoracic echocardiogram revealed a 13-mm VSD with left-to-right shunt. …”
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Early Trends in Cystatin C and Outcomes in Patients with Cirrhosis and Acute Kidney Injury by Justin M. Belcher, Arun J. Sanyal, Guadalupe Garcia-Tsao, Naheed Ansari, Steven G. Coca, Michael G. Shlipak, Chirag R. Parikh

“…Cystatin C, a low-molecular-weight cysteine proteinase inhibitor, is a potentially more accurate marker of glomerular filtration. Methods. We conducted a prospective multicenter study in patients with cirrhosis comparing changes in cystatin and creatinine immediately following onset of AKI as predictors of a composite endpoint of dialysis or mortality. …”
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SIX1 expression and its clinicopathological significance: difference between classic and follicular variant papillary thyroid carcinoma by Elzahraa Ibrahim Khalil, Ahmed S. Issa, Rehab M. Kamal

“…Conclusions The findings of this study indicate that SIX1 expression is a marker of poor prognosis in PTC, suggesting that its high expression is linked with more aggressive tumor characteristics and advanced disease stages. …”
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Lysosomal damage promotes autophagy-based unconventional secretion of the Parkinson’s disease protein PARK7 by Biplab Kumar Dash, Yasuomi Urano, Noriko Noguchi

“…Results: Upon LLOMe treatment, PARK7 translocates to damaged lysosomes, colocalizing with galectin-3 (LGALS3), a marker of lysosomal damage. Following LLOMe washout, an increase in lysophagy flux was observed, enhancing the secretion of both PARK7 and LGALS3. …”
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Right ventricular dyssynchrony predicts outcome in pulmonary arterial hypertension when assessed in multiple cardiac magnetic resonance views by Anthony Lindholm, Barbro Kjellström, Göran Rådegran, Håkan Arheden, Ellen Ostenfeld

“…Background: Right ventricular (RV) dyssynchrony or post systolic contraction (PSC) causes inefficient pumping and has not been investigated as a prognostic marker in pulmonary arterial hypertension (PAH).The objective was to investigate if RV dyssynchrony and PSC are prognostic markers of transplantation-free survival in PAH and if multiple RV views improve prognostication. …”
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Evaluating the usefulness of plasma chromogranin A measurement in cyclic ACTH-dependent Cushing’s syndrome by Keisuke Kakizawa, Miho Yamashita, Yuto Kawauchi, Akira Ikeya, Kenji Ohba, Akio Matsushita

“…The experience in evaluating this patient prompted us to investigate the potential use of plasma chromogranin A as a diagnostic marker of ACTH-dependent Cushing’s syndrome. A retrospective study was conducted to determine the efficacy of plasma chromogranin A in three patients with ectopic ACTH syndrome (EAS), including the present case, and six patients with Cushing’s disease (CD) who visited our hospital between 2018 and 2021. …”
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Stenosing Crohn’s disease patients display gut autophagy/oxidative stress imbalance by Leonardo Schirone, Maria Carla Di Paolo, Daniele Vecchio, Cristina Nocella, Alessandra D’Amico, Riccardo Urgesi, Lorella Pallotta, Gianfranco Fanello, Giuseppe Villotti, Maria Giovanna Graziani, Mariangela Peruzzi, Elena De Falco, Roberto Carnevale, Sebastiano Sciarretta, Giacomo Frati, Cristiano Pagnini

“…This was paralleled by an increase in oxidative stress markers, including sNOX2-dp and H2O2, and a decrease in the antioxidant capacity measured by HBA, suggesting an imbalance in autophagy and oxidative stress mechanisms. …”
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Serum Cytokeratin-18 Is Associated with NOX2-Generated Oxidative Stress in Patients with Nonalcoholic Fatty Liver by M. Del Ben, L. Polimeni, F. Baratta, S. Bartimoccia, R. Carnevale, L. Loffredo, P. Pignatelli, F. Violi, F. Angelico

“…The aim was to determine the association of oxidative stress with cytokeratin-18 M30 fragment levels, a marker of hepatocyte apoptosis. Methods. Steatosis severity was defined according to Hamaguchi’s echographic criteria in 209 patients with nonalcoholic fatty liver. …”
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