Analysis of the correlation between the dose exposure intensity and apatinib in advanced gastric cancer: a retrospective cohort study by Xiao Ma, Xiao Ma, Lan Gao, Siying Che, Chaofeng Tao

“…The relationship between HDEI and LDEI and clinical outcomes was analyzed by using the Kaplan-Meier curve and χ2 test.Results61 patients were enrolled and assigned into two retrospective cohorts. …”
Get full text

Knowledge discovery from database: MRI radiomic features to assess recurrence risk in high-grade meningiomas by Chen Chen, Lifang Hao, Bin Bai, Guijun Zhang

“…Combinations of data preprocessing methods, including normalization (Min-Max, Z-score, Mean), dimensionality reduction (Pearson Correlation Coefficients (PCC)), feature selector (max-Number, cluster) and ten-fold cross-validation were analyzed for their prediction performance. Kaplan–Meier curve, Cox proportional hazards regression model were used and concordance index (C-index), integrated Brier score (IBS) were selected. …”
Get full text

Mortality and Its Predictors among Adult Human Immune-Deficiency Virus-Infected Patients Attending Their Antiretroviral Treatment at Health Centers, Addis Ababa, Ethiopia: Multicen... by Selam Tesfayohannes, Sisay Shine, Abinet Mekuria, Sisay Moges

“…Regressions using the Kaplan‐Meier and Cox proportional hazards were employed. …”
Get full text

Association between prognosis and the use of angiotensin‐converting enzyme inhibitors and/or angiotensin II receptor blockers in frail patients with heart failure with preserved ej... by Akihiro Sunaga, Shungo Hikoso, Shunsuke Tamaki, Masahiro Seo, Masamichi Yano, Takaharu Hayashi, Akito Nakagawa, Yusuke Nakagawa, Hiroyuki Kurakami, Tomomi Yamada, Tetsuhisa Kitamura, Taiki Sato, Bolrathanak Oeun, Hirota Kida, Yohei Sotomi, Tomoharu Dohi, Katsuki Okada, Hiroya Mizuno, Daisaku Nakatani, Takahisa Yamada, Yoshio Yasumura, Yasushi Sakata, OCVC‐Heart Failure Investigators

“…Of 1059 patients, median age was 83 years and 45% were male. Kaplan–Meier analysis showed that the risk of composite endpoint (log‐rank P = 0.001) and all‐cause death (log‐rank P = 0.005) in patients with ACE‐I/ARB was lower in those with CFS ≥ 5, but similar between patients with and without ACE‐I/ARB in patients with CFS ≤ 4 (composite endpoint: log‐rank P = 0.830; all‐cause death: log‐rank P = 0.192). …”
Get full text

Excessive occupational sitting increases risk of cardiovascular events among working individuals with type 1 diabetes in the prospective Finnish Diabetic Nephropathy Study by Matias Seppälä, Heidi Lukander, Johan Wadén, Marika I. Eriksson, Valma Harjutsalo, Per-Henrik Groop, Lena M. Thorn, FinnDiane Study Group

“…Multivariable logistic regression identified independently associated factors, while Kaplan-Meier curves and Cox proportional hazard models were used for prospective analyses. …”
Get full text

Outcomes and risk factors of transported patients with extracorporeal membrane oxygenation: An ECMO center experience by Lingjuan Liu, Dingji Hu, Tong Hao, Shanshan Chen, Lei Chen, Yike Zhu, Chenhui Jin, Jing Wu, Haoya Fu, Haibo Qiu, Yi Yang, Songqiao Liu

“…The 28-day survival rate for ECMO patients was determined using Kaplan–Meier analysis, while logistic regression identified prognostic factors. …”
Get full text

Pembrolizumab hybrid dosing is non-inferior to flat dosing in advanced non-small cell lung cancer: a real-world, retrospective bicenter cohort study by Egbert F Smit, Willemijn S M E Theelen, Michiel M Smeenk, Vincent van der Noort, Jeroen M A Hendrikx, Hanieh Abedian Kalkhoran

“…Overall survival (OS) and progression-free survival (PFS) were assessed by Kaplan-Meier estimation, compared by log-rank test and HRs were calculated with the Cox proportional hazards model in both unweighted and inverse probability of treatment weighted (IPTW) cohorts. …”
Get full text

Unexpected identification of peak systolic velocity in the radial artery as a risk factor for functional primary patency of radiocephalic fistulas by Rui Cong, Songxiu Li, Shasha Shi

“…Se utilizó el análisis de Kaplan-Meier para ilustrar las diferencias en la permeabilidad primaria funcional de las fístulas radiocefálicas, mientras que se emplearon pruebas log-rank para comparar las curvas de supervivencia. …”
Get full text

Unexpected identification of peak systolic velocity in the radial artery as a risk factor for functional primary patency of radiocephalic fistulas by Rui Cong, Songxiu Li, Shasha Shi

“…Se utilizó el análisis de Kaplan-Meier para ilustrar las diferencias en la permeabilidad primaria funcional de las fístulas radiocefálicas, mientras que se emplearon pruebas log-rank para comparar las curvas de supervivencia. …”
Get full text

Associations of healthy lifestyle and family income to poverty ratio with all-cause mortality among people with prediabetes and diabetes: a prospective cohort study by Zhu Li, Lin Zhou, Yongshi Wu, Tao Ding, Yuxin Gan, Xiang Fan

“…Cox proportional hazard models were used to calculate hazard ratios (HRs) and 95% confidence intervals, Kaplan-Meier survival curve was used to analyze the all-cause mortality associated with PIR and lifestyle. …”
Get full text

To construct and validate a risk score model of angiogenesis-related genes to predict the prognosis of hepatocellular carcinoma by Duangui Gao, Yuan Lu, Tianpeng Jiang, Qinghong Duan, Zhi Huang

“…Cox regression analysis, Kaplan Meier (KM) curve, ROC curve, and decision-curve analysis will be used to evaluate and examine the risk score prediction effect of the model. …”
Get full text

MRI动脉期强化模式预测肝内胆管细胞癌患者的预后 by 陈美成, 周小琦, 马瑞霞, 冯仕庭, 马玲

“…方法回顾性分析2018年1月至2021年12月在中山大学附属第一医院手术治疗，术后病理证实为ICC的93例患者的临床、术前增强MRI、术后病理、术后随访资料。采用Kaplan-Meier生存曲线分析比较MRI增强扫描动脉期强化模式不同的三组间的DFS和OS，Cox回归分析影响ICC术后DFS和OS的危险因素。…”
Get full text

Outcomes with bridging radiation therapy prior to chimeric antigen receptor T-cell therapy in patients with aggressive large B-cell lymphomas by Gohar S. Manzar, Chelsea C. Pinnix, Stephanie O. Dudzinski, Kathryn E. Marqueen, Elaine E. Cha, Lewis F. Nasr, Alison K. Yoder, Michael K. Rooney, Paolo Strati, Sairah Ahmed, Chijioke Nze, Ranjit Nair, Luis E. Fayad, Michael Wang, Loretta J. Nastoupil, Jason R. Westin, Christopher R. Flowers, Sattva S. Neelapu, Jillian R. Gunther, Bouthaina S. Dabaja, Susan Y. Wu, Penny Q. Fang

“…Survival was modeled using Kaplan-Meier or Cox regression models for events distributed over time, or binary logistic regression for disease response. …”
Get full text

RNA结合蛋白PTBP1与磷酸化-AXL共表达在骨肉瘤中的临床意义 by 李湘湘, 徐雯莉, 卢正宇, 何安芳, 王震, 刘妮, 乐雨婷, 彭挺生

“…免疫组化结果显示PTBP1和p-AXL蛋白的表达在骨肉瘤组织中显著高于非恶性骨组织；p-AXL阳性表达率与肺转移相关（<italic>P</italic>=0.025）；Kaplan-Meier分析发现肺转移、复发、PTBP1表达及PTBP1/p-AXL共表达等因素与骨肉瘤患者不良总生存期相关；且多变量Cox回归分析显示肺转移（<italic>P</italic>&lt;0.000 1）、PTBP1表达阳性（<italic>P</italic>=0.041）是骨肉瘤患者总生存期（OS）独立危险因素；PTBP1/p-AXL共表达患者的OS（<italic>P</italic>=0.017）和PFS（<italic>P</italic>=0.043）均低于非PTBP1/p-AXL共表达患者。…”
Get full text

双链ＲＮＡ依赖的蛋白激酶在非小细胞肺癌预后预测及靶向治疗中的作用

“…【方法】 免疫组化检测２１２例ＮＳＣＬＣ中ＰＫＲ、ＩＧＦ-１Ｒ表达情况，并用于Ｋａｐｌａｎ-Ｍｅｉｅｒ生存分析。Ｗｅｓｔｅｒｎ Ｂｌｏｔｔｉｎｇ检测１３种肺癌细胞株ＰＫＲ、ｐ-ＰＫＲ表达；磺基罗丹明Ｂ法（ＳＲＢ）检测ＰＰＰ、Ｒａｐａｍｙｃｉｎ等药物作用后对高表达及低表达ｐ-ＰＫＲ细胞的抑制率。…”
Get full text

The Association Between the CALLY Index and All-Cause Mortality in Patients with COPD: Results from the Cohort Study of NHANES 2007&ndash;2010 by Ding Y, Liu Y, Yu J, Cai C, Fu L, Zhu J, Yang S, Jiang Y, Wang J

“…The study utilized Kaplan-Meier curves, restricted cubic spline (RCS) curves, and Cox regression analysis to evaluate the relationship between the CALLY index and the risk of all-cause mortality in COPD patients. …”
Get full text

Probiotics Can Boost the Antitumor Immunity of CD8+T Cells in BALB/c Mice and Patients with Colorectal Carcinoma by Jie Mao, Shu-Ze Zhang, Peng Du, Zhi-Bin Cheng, Huan Hu, Shi-Yao Wang

“…The results of flow cytometry also showed that the proportion of CD8+T cells in the probiotics group was higher than that in the nonprobiotics group (P=0.029). Kaplan-Meier survival estimates also showed that the CD8+T cells, TNM stage, pathology grade, lymphatic metastasis, and probiotic treatment were significantly associated with the progression-free survival (PFS) (χ2=9.684, P=0.002 for CD8+T cells; χ2=5.878, P=0.015 for TNM stage; χ2=7.398, P=0.004 for pathology grade; χ2=8.847, P=0.003 for Lymphatic metastasis; and χ2=4.622, P=0.032 for the group (group A was treated with probiotics before surgery; group B was not treated with probiotics)). …”
Get full text

Real-world ePRO use and clinical outcomes using electronic patient-reported symptom monitoring for patients with advanced non-small-cell lung cancer receiving first-line pembrolizu... by L. Johnetta Blakely, Sabine Oskar, Ian Kudel, Ashley Roush, Zoya Shamsi, Toni Perry, Annette Christianson, Brittni Smith, Thomas Burke

“…Those initiating pembrolizumab from 1 July 2017 to 30 June 2019, identified retrospectively (historical cohort), were compared with those initiating pembrolizumab from 1 October 2019 to 30 September 2021 who were prospectively offered Noona (standard of care [SoC] cohort). The Kaplan–Meier method and Cox proportional hazards models were used to compare pembrolizumab real-world time on treatment (rwToT; primary outcome measure) and rw time to next treatment or death (rwTTNTD) between historical and SoC cohorts. …”

Comprehensive pan-cancer analysis reveals NTN1 as an immune infiltrate risk factor and its potential prognostic value in SKCM by Fuxiang Luan, Yuying Cui, Ruizhe Huang, Zhuojie Yang, Shishi Qiao

“…Prognostic value was evaluated through univariate Cox regression and Kaplan–Meier methods. Mutation and methylation analyses were conducted using the cBioPortal and SMART databases. …”
Get full text

输注陈旧红细胞对肝细胞癌切除术后病人预后的影响 by 薛瑞峰, 赵崇希, 王培宗, 陈东泰, 陈晓辉, 曾维安, 李强

“…结果术中输注红细胞的病人共251例（20.6%），除14例患者新旧红细胞均有输注外，新鲜红细胞组112例，陈旧红细胞组125例。Kaplan–Meier生存分析显示输血组的总生存时间，肝内无复发生存时间，肝外无转移生存时间都更差（<italic>P</italic>&lt;0.001），Cox多因素回归分析进一步提示输注陈旧红细胞是总生存时间（HR<italic>=</italic>1.417， <italic>P</italic>=0.049）和肝内无复发生存时间（HR<italic>=</italic>1.519， <italic>P</italic>=0.013）的独立影响因素，新鲜红细胞却不是。…”
Get full text