Marked Direct Hyperbilirubinemia due to Ceftriaxone in an Adult with Sickle Cell Disease by Daniyeh Khurram, Leonid Shamban, Robert Kornas, Maryann Paul

“…Ceftriaxone may be associated with marked direct hyperbilirubinemia particularly in sickle cell patients with chronic liver chemistry abnormalities. …”
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Is Hydroxyurea Treatment Changing the Life of Children with Sickle Cell Disease? by Mohammed Ali Al Sabbah, Mahmoud Radaideh, Shafeeka Mohammed Saleh, Sura Ahmed Al-Doory, Amal Mahmoud Abdalqader, Fatima Farid Mir, Aya Mohammed

“…Background: Sickle cell disease (SCD) is a prevalent hemoglobinopathy involving sickled hemoglobin that causes multiorgan disease due to chronic recurrent vaso-occlusion and hemolysis. …”
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Impact of hydroxyurea on clinical and biological parameters of sickle cell anemia in children in Abidjan by MIREILLE YAYO- AYE, Adia Eusèbe Adjambri, Boidy Kouakou, Rebecca N'guessan-Blao, Louis Missa Adjé, Taïratou Kamagaté, Vincent Yapo, Duni Sawadogo

“… Background: The lives of individuals affected by sickle cell disease are marked by painful crises sometimes accompanied by complications. …”
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Identifying strokes in Nigerian children with sickle cell disease as part of clinical trials: training curriculum for healthcare professionals in low-income settings by Djamila L. Ghafuri, Halima Bello-Manga, Fenella J. Kirkham, Mariana Ciobanu, Edwin Trevathan, Edwin Trevathan, Mark Rodeghier, Michael R. DeBaun, Michael R. DeBaun, Lori C. Jordan

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Leucocytosis and Asymptomatic Urinary Tract Infections in Sickle Cell Patients at a Tertiary Hospital in Zambia by Taonga Musonda, Mildred Zulu, Mulemba Samutela, Annie Kalonda, Hamakwa Mantina, Pauline Okuku, Musalula Sinkala, Panji Nkhoma

“…Sickle cell anaemia (SCA) is an inherited disease resulting from mutations in the β-globin chain of adult haemoglobin that results in the formation of homozygous sickle haemoglobin. …”
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Extensive Bone Marrow Necrosis: Initial Presentation in Sickle Cell Anemia—A Case Report and Review of the Literature by Sameera A. Alsafwani, Abdulwahed Al-Saeed, Rehab Bukhamsin

“…The patient was not known previously to have SCD, when suddenly she presented with severe cytopenias and marked elevation in serum lactate dehydrogenase (LDH). …”
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HbSC Disease and Spontaneous Epidural Hematoma with Kernohan’s Notch Phenomena by Meera Yogarajah, Chidozie Charles Agu, Bhradeev Sivasambu, Mark A. Mittler

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Harvesting & Postharvest Handling of Stonefruit in Florida by Jeffrey K. Brecht, Mark A. Ritenour, Ali Sarkhosh, Mercy Olmstead, Jose X. Chaparro, Jerry A. Bartz, Steven A. Sargent, John Van Sickle

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Hyperhemolysis Syndrome without Underlying Hematologic Disease by Lauren Anne Eberly, Diaa Osman, Nathaniel Perryman Collins

“…Hyperhemolysis is characterized by a life-threatening hemolytic transfusion reaction, with hemoglobin (Hb) and hematocrit (Hct) dropping markedly lower than before transfusion. This phenomenon, commonly described in sickle cell disease, is a rare occurrence in patients without hemoglobinopathies. …”
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