Abnormal cytoskeletal remodeling but normal neuronal excitability in a mouse model of the recurrent developmental and epileptic encephalopathy-susceptibility KCNB1-p.R312H variant by Alessandro Bortolami, Elena Forzisi Kathera-Ibarra, Anastasia Balatsky, Mansi Dubey, Rusheel Amin, Srinidi Venkateswaran, Stefania Dutto, Ishan Seth, Adam Ashor, Angel Nwandiko, Ping-Yue Pan, David P. Crockett, Federico Sesti

“…Together these results demonstrate that Kv channels can cause multiple conditions, including epileptic seizures, through mechanisms that do not involve their conducting functions and put forward the idea that the etiology of DEE may be primarily non-ionic.…”
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Advancing precision medicine: the transformative role of artificial intelligence in immunogenomics, radiomics, and pathomics for biomarker discovery and immunotherapy optimization by Luchen Chang, Jiamei Liu, Jialin Zhu, Shuyue Guo, Yao Wang, Zhiwei Zhou, Xi Wei

“…These improvements are expected to lead to more accurate, personalized treatment strategies and ultimately better patient outcomes, marking a significant step forward in the evolution of precision medicine.…”
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Comparative Evaluation of AI-Based Multi-Spectral Imaging and PCR-Based Assays for Early Detection of <i>Botrytis cinerea</i> Infection on Pepper Plants by Dimitrios Kapetas, Eleni Kalogeropoulou, Panagiotis Christakakis, Christos Klaridopoulos, Eleftheria Maria Pechlivani

“…The study demonstrates early and accurate detection of <i>B. cinerea</i> on pepper plants by combining segmentation techniques with Transformer model descriptors, ensembled for classification. This approach marks a significant step forward in the detection and management of crop diseases, highlighting the potential to integrate such methods into <i>in situ</i> systems like mobile apps or robots.…”
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Real-Time Neuropsychological Testing for Hydrocephalus: Ultra-Fast Neuropsychological Testing During Infusion and Tap Test in Patients with Idiopathic Normal-Pressure Hydrocephalus by Ilaria Guarracino, Sara Fabbro, Daniele Piccolo, Serena D’Agostini, Miran Skrap, Enrico Belgrado, Marco Vindigni, Francesco Tuniz, Barbara Tomasino

“…T0 (<i>p</i> < 0.001), suggesting a more marked improvement in patients’ executive abilities at T2 and a smaller improvement at T1. …”
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Lattes/Lattara (Hérault), comptoir étrusque du littoral languedocien by Éric Gailledrat, Ariane Vacheret

“…This combined with the presence of new epigraphic documents (property marks on ceramics) makes it possible to assume that Etruscans were physically present in Lattara. …”
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Balancing selection at a wing pattern locus is associated with major shifts in genome-wide patterns of diversity and gene flow by Rodríguez de Cara, María Ángeles, Jay, Paul, Rougemont, Quentin, Chouteau, Mathieu, Whibley, Annabel, Huber, Barbara, Piron-Prunier, Florence, Ramos, Renato Rogner, Freitas, André V. L., Salazar, Camilo, Silva-Brandão, Karina Lucas, Torres, Tatiana Teixeira, Joron, Mathieu

“…Testing this hypothesis with forward simulations supported the observation of increased diversity in populations with the supergene. …”
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Dynamic EIT technology for real-time non-invasive monitoring of acute pulmonary embolism: a porcine model experiment by Junyao Li, Mingxu Zhu, Yitong Guo, Weichen Li, Qing He, Yu Wang, Yuxuan Liu, Benyuan Liu, Yang Liu, Weice Wang, Zhenyu Ji, Xuetao Shi

“…This enabled the extraction of indicators such as Amplitude, Forward (Negative) Slope, and S ARC , which were used to assess the local pulmonary blood flow perfusion state. …”
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Le camp légionnaire romain de Mayence/Mogontiacum (Allemagne) : nouveaux résultats sur l’enceinte et la chronologie by Daniel Burger-Völlmecke

“…On the new rear rampart, which had been moved forward, a new earth-and-timber rampart was constructed, the posts of which were also set into parallel running trenches. …”
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L’aqueduc de Fontanières : un cinquième aqueduc romain à Lyon ? by Jean-Yves Barbier

“…In France, the Fourvière promontory, the original founding site of the Roman colony of Lyon/Lugdunum (Metropolis of Lyon), extends southwards into the line of hills that was left behind by the Alpine glaciers of the Lyon plateau, marking the steep eastern edge of the Massif Central at its point of contact with the Rhone Graben and river valley. …”
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Editorial by Jörg Tremmel, Marisa dos Reis, Joseph Burke, Raphaelle Schwarzberg (†)

“…As followers of the recent Review of the Rome Statute in Kampala will have noticed, reform in international criminal law is a slow process. Nevertheless, Jodoin marks a clear way forward for all future discussions on this possibility. …”
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Exploring the effects of ecological parameters on the spatial structure of genetic tree sequences by Ianni-Ravn, Mariadaria K., Petr, Martin, Racimo, Fernando

“…We carry out a series of in silico experiments using forwards-in-time simulations to determine how these parameters influence the distance between closely- and distantly-related individuals. …”
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Models of Historical Memory and past Representation of Vilnius University in the 19th-20th Centuries by Alfredas Bumblauskas

“…In the 16th-18th centuries, Vilnius University was the most eastward-forwarded outpost in the network of eastern universities, having no counterparts in terms of the area of its impact. …”
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