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    Dose-Weighted Network Pharmacology: Evaluating Traditional Chinese Medicine Formulations for Lumbar Disc Herniation by Zhou C, Xiang T, Yu Y, Ma H, Liu C, Yang F, Yang L

    Published 2025-01-01
    “…Changwen Zhou,1 Ting Xiang,2 Yu Yu,3 Hongzhong Ma,1 Ce Liu,1 Feng Yang,1,4,* Lixue Yang1,4,* 1The First Clinical Medical College, Shaanxi University of Chinese Medicine, Shaanxi, People’s Republic of China; 2Rehabilitation Department, Xiang Xi Autonomous Prefecture National Hospital, Hunan, People’s Republic of China; 3Department of Chinese Medicine, Minda Hospital of Hubei Minzu University, Hubei, People’s Republic of China; 4Department of Orthopedic Hospital, The Affiliated Hospital of Shaanxi University of Chinese Medicine, Shaanxi, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lixue Yang; Feng Yang, The First Clinical Medical College, Shaanxi University of Chinese Medicine, Vice No. 2, West Weiyang Road, Qindu District, Shaanxi, 712000, People’s Republic of China, Email ylx18391076233@163.com; yangfengdudu@163.comBackground and Purpose: Lumbar disc herniation (LDH) significantly impacts individuals, particularly those aged 40– 45. …”
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    LncRNA PTS-1 Protects Against Osteoarthritis Through the miR-8085/E2F2 Axis by Ma C, Chen Q, Wei YF, Chen SW, Liu H, Xin F, Ren YX

    Published 2025-01-01
    “…Cheng Ma,1,* Qi Chen,2,* Yi-Fan Wei,1,* Shu-Wen Chen,3 Huan Liu,4 Feng Xin,5 Yong-Xin Ren1 1Department of Orthopaedics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, People’s Republic of China; 2Department of Orthopaedics, The Affiliated Changzhou No.2 People’s Hospital of Nanjing Medical University, Changzhou, Jiangsu, People’s Republic of China; 3Department of Clinical College, The First Clinical School of Nanjing Medical University, Nanjing, Jiangsu, People’s Republic of China; 4Department of Orthopaedics, The Affiliated Huai’an No.1 People’s Hospital of Nanjing Medical University, Huai’an, Jiangsu, People’s Republic of China; 5Department of Orthopaedics, Xuzhou Cancer Hospital, Xuzhou, Jiangsu, 221005, People’s Republic of China*These authors contributed equally to this workCorrespondence: Feng Xin; Yong-Xin Ren, Email 925866554@qq.com; renyongxinjsph@163.comBackground: Osteoarthritis (OA) is a leading cause of pain, disability, and reduced mobility worldwide, characterized by metabolic imbalances in chondrocytes, extracellular matrix (ECM), and subchondral bone. …”
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