Embedding research into the organisational structure of smaller rural hospitals: building research culture and capacity and understanding perceived rural health workforce benefit by Laura Alston, Dai Pu, Sarah Wood, Michael Field, Hannah Beks, Olivia A. King, Nikita Wheaton, Catherine E. Huggins, Anna Wong Shee, Kevin Mc Namara, Vincent L. Versace

“…Methods This cross-sectional study was undertaken in a rural hospital that services rural communities classed as MM4-5 by the Modified Monash Model. The study utilised the validated Research Capacity and Culture (RCC) tool to assess the impact of a rural hospital research unit on building research capacity and culture. …”
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Stacking growth of ionically conductive MOF on biofabrics enables reliable NH3 sensor for hepatic encephalopathy diagnosis by Kai Liu, Yifan Xu, Xiaozhu Tian, Junxuan Liang, Zhihui Zhao, Jun Wang, Ziqi Zhang, Kewei Zhang, Song Yang

“…Notably, the optimized sensor yields a sixfold enhancement in response as compared with traditional EC-MOF powders. A linear regression model validated by fivefold cross-validation achieves 98.4% accuracy in NH3 concentration prediction, while the kNN classifier shows 96% accuracy in gas identification (tested on 192 samples). …”
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Common inflammatory proteins linking frailty and area-level deprivation as key drivers of cardiovascular risk in women by Yu Lin, Panayiotis Louca, Ruth C. E. Bowyer, Afroditi Kouraki, Niccolò Rossi, Mary Ni Lochlainn, Anthony Kelly, Vasileios Georgopoulos, Frances M. K. Williams, Claire J. Steves, Mario Falchi, Ana M. Valdes, Cristina Menni

“…Linear mixed models assessed associations between selected proteins, IMD, frailty, and ASCVD score. …”
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Association between total and regional body fat measured by dual-energy X-ray absorptiometry and apolipoprotein B by Chi Chen, Yimeng Gu, Junfei Xu, Yanyan Xiao, Chao Wang, Yuan Chen, Hui Huang, Qingguang Chen, Yilei Chen, Qi Chen, Ningjian Wang, Hao Lu

“…The associations of total and regional fat with apoB levels were evaluated using linear regression models. Following adjustment for demographic, lifestyle, and clinical risk factors, whole-body fat percentage was positively associated with apoB levels. …”
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The impact of pre-pregnancy overweight/obesity on the birth weight of offspring born from women with polycystic ovarian syndrome by Jiejing Jiao, Yiyuan Zhang, Jiayi Zhou, Rui Lv, Linlin Cui

“…The Generalized estimating equation (GEE) model was performed to compare the outcomes. The mediation model was used to evaluate the intermediary effect of pre-pregnancy BMI. …”
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Predicting the oral health-related behaviors of the Iranian elderly based on the extended theory of planned behavior by Saeid Bashirian, Sahar Khoshravesh, Erfan Ayubi, Mahrokh Amiri, Akram Karimi-Shahanjarini, Majid Barati, Parshang Faghih Solaymani

“…This model could explain 40% of the variance in the oral health behaviors of the elderly. …”
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Association between Lactate dehydrogenase and 28-day all-cause mortality in patients with non-traumatic Intracerebral hemorrhage: A retrospective analysis of the MIMIC-IV database by Jiahui Feng, Renjie Liu, Xuan Chen

“…Restricted cubic spline (RCS) models revealed an L-shaped association between LDH levels and the 28-day all-cause mortality rate, indicating a non-linear relationship (P < 0.001). …”
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Association of life’s crucial 9 score with benign prostatic hyperplasia: a cross-sectional study by Haoran Wang, Runhua Tang, Shuhang Luo, Huimin Hou, Jianyong Liu, Ming Liu, Jianye Wang

“…Results A higher LC9 score was significantly associated with a lower risk of BPH in both continuous and categorical models (P < 0.001). The association demonstrated a linear dose-response relationship, with the inflection point at an LC9 score of 72.5. …”
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Associations of Midlife Leukocyte Telomere Length With Measures of Left Atrial Function in Community‐Dwelling Older Adults: The ARIC Study by Romil R. Parikh, Nathan Pankratz, John A. Lane, Dan E. Arking, Anne Eaton, Lin Yee Chen, Pamela L. Lutsey, Weihong Tang

“…Results LTL was weakly correlated with chronological age at blood draw for LTL measurement (r=−0.12; P<0.001). In models adjusted for chronological age at blood draw for LTL measurement, whole genome sequencing platform, visit for blood draw, cardiometabolic risk factors, and coronary heart disease, longer LTL was associated with greater (better) LA contractile strain (β=0.29 [95% CI, 0.10–0.47]; P=0.006) and LA reservoir strain (β=0.35 [95% CI, 0.12–0.59]; P=0.003) but not LA conduit strain (β=0.05 [95% CI, −0.12 to 0.21]; P=0.575). …”
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Association between endothelial activation and stress index and all-cause mortality risk in sepsis patients: a retrospective cohort analysis utilizing the MIMIC-IV database by Nanhong Li, Ji Yin, Yu Zeng, Shan Li, Chenyang Huang, Guangqin Chen, Haihua Luo, Yong Jiang

“…The interplay between the mortality and log2–EASIX values in individuals with sepsis was examined via Cox regression analysis. To explore possible nonlinear relationships between log2–EASIX values and sepsis-related mortality, we applied a restricted cubic spline (RCS) model. …”
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Understanding the factors contributing to dengue virus and chikungunya virus seropositivity and seroconversion among children in Kenya. by Amna Tariq, Aslam Khan, Francis Mutuku, Bryson Ndenga, Donal Bisanzio, Elysse N Grossi-Soyster, Zainab Jembe, Priscilla Maina, Philip Chebii, Charles Ronga, Victoria Okuta, Angelle Desiree LaBeaud

“…We employed logistic regression built using generalized linear mixed models, to identify potential exposure risk factors for DENV and CHIKV seroconversion and seropositivity. …”
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Do Long-Acting Injectable Antipsychotics Influence Serum Levels of Brain-Derived Neurotrophic Factor in People With Schizophrenia and Schizoaffective Disorder? by Mirko Manchia, Ulker Isayeva, Roberto Collu, Diego Primavera, Luca Deriu, Edoardo Caboni, Maria Novella Iaselli, Davide Sundas, Massimo Tusconi, Clement C. Zai, Maria Scherma, Alessio Squassina, Donatella Congiu, Pasquale Paribello, Federica Pinna, Claudia Pisanu, Anna Meloni, Walter Fratta, Paola Fadda, Bernardo Carpiniello

“…Four tag single nucleotide polymorphisms (SNPs) within the BDNF gene (rs1519480, rs11030104, rs6265 [Val66Met], and rs7934165) were selected using standard parameters and analyzed with polymerase chain reaction (PCR). Mixed-effects linear regression models (MLRMs) were used to analyze longitudinal data. …”
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Association of Circulating Ceramides With Cardiac Structure and Function in the Community: The Framingham Heart Study by Chike C. Nwabuo, Meredith Duncan, Vanessa Xanthakis, Linda R. Peterson, Gary F. Mitchell, David McManus, Susan Cheng, Ramachandran S. Vasan

“…We used multivariable linear regression models to relate C16:0/C24:0 (independent variable) to the following echocardiographic measures (dependent variables; separate models for each): left ventricular mass, left ventricular ejection fraction, left atrial emptying fraction, left atrial end‐systolic volume, E/e′ (a measure of left ventricular diastolic function), and left ventricular global circumferential and longitudinal strain by speckle‐tracking echocardiography. …”
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Effect of Short‐Term Exposure to Ambient Temperatures on Parkinson's Diseases Mortality Among Elderly Aged 60 Years and Above in China, 2013–2020 by Rui Zhang, Ainan Jia, Huan Zheng, Yonghong Li, Chaonan Wang, Siyuan Wu, Songwang Wang, Qing Guo, Yu Wang, Peng Bi, Jing Wu

“…A combination of conditional logistic regression and distributed lag non‐linear model was employed to analyze the data, and the mortality burden attributed to ambient temperatures was quantified. …”
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Sex differences in proteomics of cardiovascular disease – Results from the Yale-CMD registry by Yihan Liu, Zuoheng Wang, Sean P. Collins, Jeffery Testani, Basmah Safdar

“…Differential protein expression was assessed using linear regression models, adjusting for age, race, body mass index, diabetes, dyslipidemia, hypertension, or smoking. …”
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Anatomic and Functional Outcomes of Lamellar Macular Hole and Epiretinal Membrane Foveoschisis Surgery: Predictive Factors and Associated Complications &mdash; A Retrospective Inte... by Er-reguyeg Y, Doukkali S, Hébert M, You EL, Bourgault S, Caissie M, Tourville É, Dirani A

“…Variables associated with final BCVA were assessed using a multiple linear regression model.Results: 51 subjects presented with ERMF, while 39 presented with LMH. …”
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Relationships between physical frailty, depressive symptoms, and cognitive ability among community-dwelling older adults in India by T. Muhammad, Manish Kumar, Shobhit Srivastava, Waad Ali

“…Univariate and multivariable linear regression models were used to examine the associations between frailty, depressive symptoms, and cognitive ability in older men and women, as well as frailty-cognition association by depressive status. …”
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Sex differences in loneliness, social isolation, and their impact on psychiatric symptoms and cognitive functioning in schizophrenia by Jinghui Chi, Nannan Liu, Tian Tian, Qiaona Jiang, Chenghao Lu, Yanzhe Li, Xiaofei Zhang, Yanyan Ma, Lili Wang, Shen Li

“…Psychopathology, cognitive functioning, loneliness, social isolation were assessed using the Positive and Negative Syndrome Scale (PANSS), the Repeated Battery for Assessment of Neuropsychological Status (RBANS), the UCLA (University of California, Los Angeles) Loneliness Scale (Version 3) and the Social Isolation Index (ISI). Multiple linear regression models were conducted to test the independent, relative, and synergistic efects of loneliness and social isolation on psychiatric symptoms and cognitive performance for male and female patients separately. …”
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The EAT-Lancet diet in relation nutrient intake among older adults: insights from the Gothenburg H70 birth cohort study by Anna Stubbendorff, Silke Kern, Lina Rydén, Ingmar Skoog, Jessica Samuelsson

“…Cardiometabolic risk markers and biomarkers of nutritional status, including homocysteine and haemoglobin, were measured. Linear and logistic regression models were used to examine trends across sex-specific tertiles of diet adherence, with sensitivity analyses adjusting for energy intake and comparing adequacy based on average requirement (AR) thresholds. …”
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CT changes in a randomized trial comparing early therapies in an outpatient population at high risk of severe COVID19 disease by Ilaria Mastrorosa, Alessandro Cozzi-Lepri, Giulia Matusali, Francesca Colavita, Simone Lanini, Martina Rueca, Alessandra Oliva, Giulia Berno, Alessandra Vergori, Silvia Rosati, Jessica Paulicelli, Enrico Girardi, Emanuele Nicastri, Fabrizio Maggi, Andrea Antinori, Valentina Mazzotta, the MONET Clinical Trial Group

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