Klebsiella pneumoniae in stranded California sea lions (Zalophus californianus) of Central California between 2017-2022 by Sydney N. Zotto, Robin C. Dunkin, Juliana D. Limon, Maia S. Smith, Lisabet M. Hortensius, Margaret E. Martinez, Pádraig J. Duignan, Cara Field, Esteban Soto, Dane Whitaker, Carlos Rios, Maurice Byukusenge, Bhushan Jayarao, Suresh V. Kuchipudi, Amy C. Kinsley

“…Multilocus Sequence Typing showed that all isolates belonged to Sequence type 65 and contained the K2 polysaccharide capsule and siderophore aerobactin, which are all characteristics of hypervirulent K. pneumoniae. …”
Get full text

Yield and Sensorial and Nutritional Quality of Strawberry (<i>Fragaria</i> × <i>ananassa</i> Duch.) Fruits from Plants Grown Under Different Amounts of Irrigation in Soilless Culti... by Davide Raffaelli, Rohullah Qaderi, Luca Mazzoni, Bruno Mezzetti, Franco Capocasa

“…With these interesting variations in fruit quality came a different response in plant yield. Plants belonging to the Lauretta and AN15,07,53 cultivars maintained a 98% fruit yield when grown under WS1 conditions. …”
Get full text

Mycotoxicological monitoring. Part 1. Complete mixed feed for pigs and poultry (2009–2018) by G. P. Kononenko, A. A. Burkin, Ye. V. Zotova

“…Diacetoxyscirpenol, aflatoxin В1, sterigmatocystin and cyclopiazonic acid belonged to group of rare contaminants. Level of feed contamination with T-2 toxin and emodin was found to be consistently high during the said period; in some of the years occurrence of deoxynivalenol, fumonisines as well as ochra­toxin A, citrinin, mycophenolic acid and ergoalkoloids increased. …”
Get full text

A CT-based deep learning model for preoperative prediction of spread through air spaces in clinical stage I lung adenocarcinoma by Xiaoling Ma, Weiheng He, Chong Chen, Fengmei Tan, Jun Chen, Lili Yang, Dazhi Chen, Liming Xia

“…AUC comparisons were performed by the DeLong test.ResultsThe proposed deep learning signature achieved an AUC of 0.869 (95% CI: 0.831, 0.901) in training cohort and 0.837 (95% CI: 0.831, 0.901) in validation cohort, surpassing clinical-semantic model both in training and validation cohort (all P&lt;0.01). …”
Get full text

Twelve-month follow-up of a controlled trial of a brief behavioural intervention to reduce psychological distress in young adolescent Syrian refugees by Richard A. Bryant, Rand Habashneh, Maha Ghatasheh, Aiysha Malik, Ibrahim Said Aqel, Katie S. Dawson, Sarah Watts, Mark J. D. Jordans, Felicity L. Brown, Mark van Ommeren, Aemal Akhtar

“…At 12 months there were no significant differences between treatment conditions, except that EASE was associated with less reduction in depression (estimated mean difference -1.6, 95% CI –3.2 to -0.1; p=.03; effect size, -0.3), and a greater sense of school belonging (estimated mean difference -0.3, 95% CI –5.7 to -0.2; p=.03; effect size, 5.0). …”
Get full text

Highly pathogenic bovine viral diarrhea virus BJ-11 unveils genetic evolution related to virulence in calves by Yuanyuan Zhang, Yuanyuan Zhang, Jing Cheng, Yu Guo, Yu Guo, Yibin Hu, Yibin Hu, Zhuo Zhao, Wenxiao Liu, Linyi Zhou, Peize Wu, Chunjie Cheng, Chunjie Cheng, Chun Yang, Chun Yang, Jing Yang, Jing Yang, Enqi Du, Yongqing Li, Yongqing Li

“…Phylogenetic analysis indicated that BJ-11 belongs to the BVDV 1b subtype, genetically closest to the JL-1 strain. …”
Get full text

A machine learning-based radiomics approach for differentiating patellofemoral osteoarthritis from non-patellofemoral osteoarthritis using Q-Dixon MRI by Liangjing Lyu, Jing Ren, Wenjie Lu, Jingyu Zhong, Yang Song, Yongliang Li, Weiwu Yao

“…The diagnostic performance of the three models was compared using the area under the curve (AUC) values analyzed with the Delong test. In the training set (109 patients) and internal test set (73 patients), the merged model exhibited optimal performance, with AUCs of 0.836 [95% confidence interval (CI): 0.762–0.910] and 0.826 (95% CI: 0.722–0.929), respectively. …”
Get full text

A global Corynebacterium diphtheriae genomic framework sheds light on current diphtheria reemergence by Hennart, Mélanie, Crestani, Chiara, Bridel, Sébastien, Armatys, Nathalie, Brémont, Sylvie, Carmi-Leroy, Annick, Landier, Annie, Passet, Virginie, Fonteneau, Laure, Vaux, Sophie, Toubiana, Julie, Badell, Edgar, Brisse, Sylvain

“…Results: The France-2022 isolates comprised 45 tox-positive (44 toxigenic) isolates, mostly imported, belonging to 10 sublineages (<500 distinct core genes). …”
Get full text

Body Mass Index and Its Change from Adolescence to Adulthood Are Closely Related to the Risk of Adult Metabolic Syndrome in China by Bingyang Liu, Yue Li, Jiamei Guo, Yuting Fan, Ling Li, Ping Li

“…Interestingly, the group with lower BMI but a higher increase in BMI presented the same metabolic derangements and Mets% of the group with higher BMI but lower Δ BMI. …”
Get full text

Integrated metabolomics and proteomics revealed astragaloside IV inhibiting Pdxk-mediated vitamin B6 metabolism based on liquid chromatography-tandem mass spectrometry combined wit... by Shi Qiu, Sifan Guo, Zhibo Wang, Ying Cai, Dandan Xie, Wanying Sun, Aihua Zhang

“…Astragaloside IV (ASIV) is a representative component of traditional herbs Astragalus membranaceus which belongs to medicinal food homology, but the molecular targets regulating cellular amino acid (AA) metabolism of the therapeutic effect are still unclear. …”
Get full text

Projected distribution patterns of Alpinia officinarum in China under future climate scenarios: insights from optimized Maxent and Biomod2 models by Yong Kang, Yong Kang, Fei Lin, Junmei Yin, Junmei Yin, Yongjie Han, Min Zhu, Yuhua Guo, Fenling Tang, Yamei Li

“…Alpinia officinarum, commonly known as Galangal, is not only widely used as a medicinal plant but also holds significant ornamental value in horticulture and landscape design due to its unique plant structure and floral aesthetics in China. …”
Get full text

Carboxylesterase 4A Inhibits the Malignant Biological Behavior of Nasopharyngeal Carcinoma via the PI3K/AKT Pathway by Qiaoli Chen MS, Quanxiang Hao MBBS, Yanping Yang MBBS, Limei Li PhD, Danping Li MS, Ran Zhao MS, Wanqi Wei MBBS, Lixian Deng MBBS, Jiaming Su MBBS, Ziyuan Liang MBBS, Shiyue Tang MS, Yaomin Lu MBBS, Yushan Liang PhD, Zhe Zhang PhD, Xiaoying Zhou PhD, Xue Xiao PhD, Ping Li PhD, Yi Huang PhD, Weilin Zhao PhD

“…Background Carboxylesterase 4A (CES4A) belongs to the member of the carboxylesterase family, yet there has been limited research into its malignant biological behavior in malignant tumors. …”
Get full text

Passive hyperthermia alters the resting-state functional connectivity of mouse brain by Yang Ruan, Kai Liu, Bo Li, Shaowen Qian, Hongxia Lei, Yao Xing, Gang Sun

“…After data preprocessing, we performed independent component analysis (ICA) and region of interested (ROI)-ROI functional connectivity (FC) analyses on the data of both HT (n = 13) and NC (n = 15).Results The group ICA analysis showed that the HT and the NC both included 11 intrinsic connectivity networks (ICNs), and can be divided into four types of networks: the cortical network (CN), the subcortical network (SN), the default mode network (DMN), and cerebellar networks. CN and SN belongs to sensorimotor network. Compared with NC, the functional network organization of ICNs in the HT was altered and the overall functional intensity was decreased. …”
Get full text

Contaminant-degrading bacteria are super carriers of antibiotic resistance genes in municipal landfills: A metagenomics-based study by Fang-Zhou Gao, Wei-Li Jia, Bing Li, Min Zhang, Liang-Ying He, Hong Bai, You-Sheng Liu, Guang-Guo Ying

“…Notably, several bacterial genera belonging to Pseudomonadaceae had the most antibiotic-resistant, pathogenic, and contaminant-degrading potentials than other bacteria. …”
Get full text

High fructose rewires gut glucose sensing via glucagon-like peptide 2 to impair metabolic regulation in mice by Eya Sellami, Paulo Henrique Evangelista-Silva, Caio Jordão Teixeira, Khoudia Diop, Patricia Mitchell, Fernando Forato Anhê

“…Our findings are positioned to inform novel early diagnostic tools and treatments tailored to counter high fructose-induced metabolic derangements predisposing to T2D and MASLD.…”
Get full text

High Glucose Induces Endothelial COX2 and iNOS Expression via Inhibition of Monomethyltransferase SETD8 Expression by Jie Qi, Qichao Wu, Qian Cheng, Xiangyuan Chen, Minmin Zhu, Changhong Miao

“…E26 transformation-specific sequence transcription factor-1 (ESE-1), which belongs to the E26 transformation-specific family of transcription factors, has been demonstrated to be involved in COX2 and iNOS gene transcription. …”
Get full text

Associations between changes in the gut microbiota and liver cirrhosis: a systematic review and meta-analysis by Ye Liu, Ziwei Chen, Chang Li, Tianhan Sun, Xuanmei Luo, Boyue Jiang, Meilan Liu, Qing Wang, Tong Li, Jianfu Cao, Yayu Li, Yuan Chen, Lu Kuai, Fei Xiao, Hongtao Xu, Hongyuan Cui

“…Families Enterobacteriaceae and Pasteurellaceae, belonging to the phylum Proteobacteria, along with the family Streptococcaceae and the genera Haemophilus, Streptococcus, and Veillonella, were significantly associated with liver cirrhosis compared to the control group. …”
Get full text

Antimicrobial susceptibility and epidemiological types of Legionella pneumophila human isolates from Italy (1987–2020) by Maria Scaturro, Alessio Lanni, Fabiola Mancini, Antonietta Girolamo, Silvia Fillo, Andrea Ciammaruconi, Florigio Lista, Clementina Elvezia Cocuzza, Rosario Musumeci, Christophe Ginevra, Ghislaine Descours, Sophie Jarraud, Jessica Iera, Paolo Visca, Maria Luisa Ricci

“…Results: The L. pneumophila isolates did not show significant resistance to the tested antibiotics, although a trend toward reduced sensitivity to azithromycin was observed in a subpopulation of 46 strains, most of which belonged to sequence type 1 (ST1), the second most widespread ST in Italy. …”
Get full text

Impact of pharmacist-prescriber partnerships to track antibiotic prescribing in publicly funded primary care in the Cape Town metropole, South Africa: An implementation study by O Van Hecke, Y Adegoke, M Allwood, K von Pressentin, M Namane, C Butler, M Mendelson, R Coetzee

“…Against AWaRe (access/watch/reserve) guidance, 97% of antibiotics prescribed belonged to the ‘access’ group. Conclusion. Although prescribing concordance with guidelines was good, a significant proportion of patients were prescribed an antibiotic for ‘acute cough’. …”
Get full text

The Relevance of the Virchow Node and Virchow Triad in Renal Cancer Diagnosis by Luiza-Roxana Dorobantu-Lungu, Viviana Dinca, Andrei Gegiu, Dan Spataru, Andreea Toma, Luminita Welt, Mihaela Florentina Badea, Constantin Caruntu, Cristian Scheau, Ilinca Savulescu-Fiedler

“…Renal cell carcinoma (RCC) associated with Xp11.2 translocation/gene fusion TFE3 is a rare subtype of kidney cancer that was classified in 2016 as belonging to the family of renal carcinomas with MiT gene translocation (microphthalmia-associated transcription factor). …”
Get full text