Evaluation of the Synergistic Antimicrobial Activity of Essential Oils and Cecropin A Natural Peptide on Gram-Negative Bacteria by Filippo Fratini, Chiara Pecorini, Ilaria Resci, Emma Copelotti, Francesca Paola Nocera, Basma Najar, Simone Mancini

“…In light of these considerations, the synergistic use of essential oils and Antimicrobial Peptides (AMPs) seems a viable strategy. In this study, we assessed the Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC) and Fractional Inhibitory Concentration (FIC) of three Essential Oils (EOs): winter savory (<i>Satureja montana</i>), bergamot (<i>Citrus bergamia</i>) and cinnamon (<i>Cinnamomum zeylanicum</i>) and of the insect antimicrobial peptide Cecropin A (CecA), alone and in combination with EOs, against two Gram-negative ATCC bacterial strains: <i>Escherichia coli</i> and <i>Salmonella enterica</i> serovar Typhimurium. …”
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Dietary addition of compound organic acids improves the growth performance, carcass trait, and body health of broilers by Fang Cai, Meiping Huang, Wei Liu, Xiaoling Wan, Kai Qiu, Xiao Xu

“…The acidifier upregulated PPARα, AMPK, FABP1 and MTTP expressions, and downregulated APOB100. …”
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Single-cell atlas of human pancreatic islet and acinar endothelial cells in health and diabetes by Rebecca Craig-Schapiro, Ge Li, Kevin Chen, Jesus M. Gomez-Salinero, Ryan Nachman, Aleksandra Kopacz, Ryan Schreiner, Xiaojuan Chen, Qiao Zhou, Shahin Rafii, David Redmond

“…Single-cell RNA sequencing reveals the unique molecular signatures of ISECs, including structural genes COL13A1, ESM1, PLVAP, UNC5B, and LAMA4, angiocrine genes KDR, THBS1, BMPs and CXCR4, and metabolic genes ACE, PASK and F2RL3. …”
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Bone Marrow Stromal Cells Generate a Pro-Healing Inflammasome When Cultured on Titanium–Aluminum–Vanadium Surfaces with Microscale/Nanoscale Structural Features by David J. Cohen, Christine M. Van Duyn, Jingyao Deng, Musaddiq K. Lodi, Michelle B. Gallagher, James T. Sugar, Jeremy J. Rawlinson, Preetam Ghosh, Barbara D. Boyan, Zvi Schwartz

“…MSCs on MN surfaces exhibited enhanced osteoblastic differentiation, evidenced by increased expression of RUNX2, SP7, BGLAP, BMP2, and BMPR1A (fold increases: 3.2, 1.8, 1.4, 1.3, and 1.2). …”
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Different expression of circulating microRNA profile in tibetan OSAHS with metabolic syndrome patients by Xue-feng Shi, Xiang He, Ze-rui Sun, Jie Duo, Hao Yang

“…Notably, the Wnt signaling pathway, PI3K-Akt signaling pathway, cAMP signaling pathway, and AMPK signaling pathway are implicated in the metabolic processes of glucose dysregulation and lipid homeostasis, as well as the pathogenesis of hypertension associated with OSAHS. …”
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Single-nucleotide polymorphism analysis accurately predicts multiple impairments in hippocampal activity and memory performance in a murine model of idiopathic autism by Isabel Barón-Mendoza, Luis A. Márquez, Aliesha González Arenas, Jessica Guzmán-Condado, Vladimir A. Martínez-Rojas, Johaly Anguiano-Buenfil, Montserrat Mejía-Hernández, Jorge Luis Almazán, Leonor Pérez-Martínez, Gustavo Pedraza-Alva, Emilio J. Galván, Angélica Zepeda

“…An increased proportion of synaptosomes expressing the GluA1 subunit of AMPA receptor and Nrx1β in the membrane was found in the C57BL/6J control strain, but not in C58/J mice, after cLTP induction. …”
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STRATEGY OF SOCIALLY-ANTHROPOLOGICAL DEVELOPMENT IN IDEAS AND SYSTEM OF MODERN SOCIAL PHILOSOPHY OF EDUCATION: INTEGRATION OF MODEL OF THE INSTRUMENTALISM AND THE NEOPRAGMATISM WIT... by Viktor Zinchenko

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Integrated metabolomics and proteomics analysis to provide insights into muscle atrophy of turbot Scophthalmus maximus by dietary Clostridium autoethanogenum protein by Shihui Pan, Nan Bai, Zezheng Qi, Chuwen Chen, Daisong Ma, Zhenlin Liang, Min Gu

“…Previous studies proved that high levels of dietary CAP retarded the muscle development in turbot through mammalian target of rapamycin (mTOR)/amino acid response (AAR)/adenosine monophosphate-activated protein kinase (AMPK) pathways. However, how CAP regulating these pathways was still unclear and there was no information on the comprehensive analysis for the mechanisms of CAP on fish muscle. …”
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Identification of Crucial lncRNAs for Luminal A Breast Cancer through RNA Sequencing by Xinjian Jia, Hai Lei, Xuemei Jiang, Ying Yi, Xue Luo, Junyan Li, Yu Chen, Sha Liu, Chengcheng Yang

“…Four lncRNA-nearby and coexpressed mRNA pairs of HOXC-AS3-HOXC10, AC020907.2-FXYD1, AC026461.1-MT1X, and AC132217.1-IGF2 were identified. AMPK (involved LIPE and LEP) and PPAR (involved PLIN1) were two significantly enriched pathways in luminal A breast cancer. …”
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Effect of soluble dietary fiber extracted from Lentinula edodes (Berk.) Pegler on lipid metabolism and liver protection in mice on high-fat diet by Kangxiao Guo, Kangxiao Guo, Jing Liu, Zihan Yao, Zhoujin Tan, Tao Yang

“…Lentinus edodes soluble dietary fiber decreased the expression of AMPKα and SREBP-2 in the liver, and increased the expression of PPARα, ACS, CPT1a, CYP7A1. …”
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MCT1 lactate transporter blockade re-invigorates anti-tumor immunity through metabolic rewiring of dendritic cells in melanoma by Camille Niveau, Mélanie Cettour-Cave, Stéphane Mouret, Eleonora Sosa Cuevas, Mylene Pezet, Benoît Roubinet, Hugo Gil, Florence De Fraipont, Ludovic Landemarre, Julie Charles, Philippe Saas, Caroline Aspord

“…Strikingly, modulation of the mTOR/AMPK-dependent metabolic pathways and/or the MCT1 lactate transporter rescue cDC2s and cDC1s from skewing by tumor-derived glycans, Sialyl-Tn antigen and Fucose, and restore anti-tumor T-cell fitness. …”
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Comparison of conventional versus robotic-assisted total hip arthroplasty using the Mako system: An Italian retrospective study by Roberta Banchetti, Silvia Dari, Maria Elisabetta Ricciarini, Domenico Lup, Francesco Carpinteri, Fabio Catani, Patrizio Caldora

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Identification of Potential miRNA-mRNA Regulatory Network Contributing to Parkinson’s Disease by Xi Yin, Miao Wang, Wei Wang, Tong Chen, Ge Song, Yixuan Niu, Ziying Jiang, Zhongbao Gao, Zhenfu Wang

“…Further functional enrichment analysis identified 10 PD-related hub genes, including RAC1, IRS2, LEPR, PPARGC1A, CAMKK2, RAB10, RAB13, RAB27B, RAB11A, and JAK2, which were mainly involved in Rab protein signaling transduction, AMPK signaling pathway, and signaling by Leptin. …”
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The β-Lactamase Gene Profile and a Plasmid-Carrying Multiple Heavy Metal Resistance Genes of Enterobacter cloacae by Chongyang Wu, Chaoqin Lin, Xinyi Zhu, Hongmao Liu, Wangxiao Zhou, Junwan Lu, Licheng Zhu, Qiyu Bao, Cong Cheng, Yunliang Hu

“…The extended-spectrum β-lactamases (ESBLs) (blaSHV-12 and blaCTX-M-9a) and AmpC (blaMIR) were encoded on the chromosome, and the pY546 plasmid contained several clusters of genes conferring resistance to metals, such as copper (pco), arsenic (ars), tellurite (ter), and tetrathionate (ttr), and genes encoding many divalent cation transporter proteins. …”
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High-starchy carbohydrate diet aggravates NAFLD by increasing fatty acids influx mediated by NOX2 by Yuqi Gao, Rui Hua, Kezheng Peng, Yuemiao Yin, Chenye Zeng, Yannan Guo, Yida Wang, Liyuan Li, Xue Li, Ying Qiu, Zhao Wang

“…In addition, the interaction between AMPKα1 and p47phox was the pathway that mediated the high expression of NOX2 induced by a HCD. …”
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Bacteraemia in a Nigerian hospital: Implementing antimicrobial resistance surveillance by Adewale A. Amupitan, Adeyemi T. Adeyemo, Adefunke O. Amupitan, Temitope O. Obadare, Aaron O. Aboderin

“…Sixteen (30.2%) of 53 Gram-negative isolates were extended-spectrum beta-lactamase producers, predominantly harbouring blaCTX-M, three (5.7%) were AmpC beta-lactamase producers, and 20 (37.7%) were carbapenem-resistant, predominantly harbouring blaKPC. …”
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Prospects of Back Surface Field Effect in Ultra-Thin High-Efficiency CdS/CdTe Solar Cells from Numerical Modeling by Nowshad Amin, M. A. Matin, M. M. Aliyu, M. A. Alghoul, M. R. Karim, K. Sopian

“…Results of numerical analysis using AMPS-1D simulator in exploring the possibility of ultrathin, high efficiency, and stable CdS/CdTe cells are presented. …”
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A multilayered regulatory network mediated by protein phosphatase 4 controls carbon catabolite repression and de-repression in Magnaporthe oryzae by Zhicheng Huang, Qing Wang, Yan Li, Pengyun Huang, Jian Liao, Jing Wang, Hui Li, Yingying Cai, Jiaoyu Wang, Xiaohong Liu, Fu-Cheng Lin, Jianping Lu

“…We demonstrate that the protein phosphatase 4 complex (Pp4c and Smek1 subunits), the AMP-activated protein kinase (AMPK) Snf1, and the transcriptional regulators CreA (repressor) and Crf1 (activator) collaboratively regulate the utilization of non-preferred carbon sources. …”
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Soluble Epoxide Hydrolase Inhibitor and 14,15-Epoxyeicosatrienoic Acid-Facilitated Long-Term Potentiation through cAMP and CaMKII in the Hippocampus by Han-Fang Wu, Yi-Ju Chen, Su-Zhen Wu, Chi-Wei Lee, I-Tuan Chen, Yi-Chao Lee, Chi-Chen Huang, Chung-Hsi Hsing, Chih-Wei Tang, Hui-Ching Lin

“…TPPU- or 14,15-EET-facilitated FSK-mediated LTP can be potentiated by an A1 adenosine receptor antagonist and a phosphodiesterase inhibitor, but is prevented by a cAMP-dependent protein kinase (PKA) inhibitor. sEHI and 14,15-EET upregulated the activation of extracellular signal-regulated kinases (ERKs) and Ca2+/calmodulin- (CaM-) dependent protein kinase II (CaMKII). …”
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Effects of exercise training on the nigrostriatal glutamatergic pathway and receptor interactions in Parkinson’s disease: a systematic review by Shahid Ishaq, Iqbal Ali Shah, Shin-Da Lee, Shin-Da Lee, Bor-Tsang Wu

“…It also downregulated mGluR5 and modulated the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor subunits: GluA1 was downregulated, inhibiting long-term potentiation, while GluA2 and GluA3 were upregulated in the nigrostriatal pathway in PD animal models. …”
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