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1561
Research on the Application Potential of New Nano-Oil Displacement Agents to Improve Shale Oil Recovery Rates
Published 2024-12-01“…To meet the demand for enhanced oil recovery in shale reservoirs and to improve the fluidity of shale oil while strengthening its imbibition effect, a multifunctional, thermally stable nanofluid agent, SDP-3, was synthesized using acrylamide (AM) and 2-acrylamido-2-methylpropanesulfonicacid (AMPS) as the primary raw materials. A series of characterizations and tests were conducted to evaluate its interfacial properties, stability, viscosity reduction performance, wettability, and imbibition-driven oil recovery capabilities. …”
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1562
Anti-diabetic and anti-hyperlipidemic effects of sea cucumber (Cucumaria frondosa) gonad hydrolysates in type II diabetic rats
Published 2022-11-01“…In addition, mechanism studies showed that SCGH improved glucose metabolism via activating the IRS/Akt signaling pathway, and promoted lipid metabolism via activating the AMPK signaling pathway. In summary, these findings suggested that SCGH have potential anti-diabetic effects by improving insulin resistance and lipid metabolism disorders.…”
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1563
Interface Study of ITO/ZnO and ITO/SnO2 Complex Transparent Conductive Layers and Their Effect on CdTe Solar Cells
Published 2013-01-01“…The effects of their use in CdTe solar cells were studied by AMPS-1D software simulation using experiment values obtained from ZnO, ITO, and SnO2. …”
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1564
Comparison of Gene Expression in Human Embryonic Stem Cells, hESC-Derived Mesenchymal Stem Cells and Human Mesenchymal Stem Cells
Published 2011-01-01“…Transcript analysis of membrane antigens suggests that IL1R1low, BMPR1Blow, FLT4low, LRRC32low, and CD34 may be good candidates for the detection and isolation of the most primitive hMSCs. …”
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1565
From Integer Programming to Machine Learning: A Technical Review on Solving University Timetabling Problems
Published 2025-01-01“…For three types of timetabling problems including course timetabling, class timetabling, and exam timetabling, we dive deeper into the commercial solvers CPLEX (47), Gurobi (11), Lingo (5), Open Solver (4), C++ GLPK (4), AIMMS (2), GAMS (2), XPRESS (2), CELCAT (1), AMPL (1), and Google OR-Tools CP-SAT (1) and identify that CPLEX is the most frequently used integer programming solver. …”
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1566
Veratrilla baillonii Franch alleviate the symptoms of diabetes in type 2 diabetic rats induced by high-fat diet and streptozotocin
Published 2024-05-01“…Further investigation suggested that WVBF modulates the signal transductions of the IRS1/PI3K/AKT/GLUT4 and AMPK pathways. These f indings demonstrate potentials of WVBF in the treatment of T2DM and possible mechanisms for its hepatoprotective activities.…”
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1567
Design of Interface ASIC with Power-Saving Switches for Capacitive Accelerometers
Published 2025-01-01“…To minimize average power consumption, a switched operational amplifier (op-amp) technique is adopted, which temporarily disconnects idle op-amps from the power supply. …”
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1568
Tumor Necrosis Factor Alpha Mediates GABAA Receptor Trafficking to the Plasma Membrane of Spinal Cord Neurons In Vivo
Published 2012-01-01“…TNFα contributes to excitotoxicity by increasing GluA2-lacking AMPA receptor (AMPAR) trafficking to the neuronal plasma membrane. …”
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1569
Heme Oxygenase 1/Peroxisome Proliferator-Activated Receptor Gamma Pathway Protects Intimal Hyperplasia and Mitigates Arteriovenous Fistula Dysfunction by Regulating Oxidative Stres...
Published 2022-01-01“…These DEmRNAs were significantly enriched in the PPAR signaling pathway, AMPK signaling pathway, glucagon signaling pathway, IL-17 signaling pathway, and Toll-like receptor signaling pathway. …”
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1570
Inferring transcriptomic dynamics implicated in odor fatty acid accumulation in adipose tissue of Hulun Buir sheep from birth to market
Published 2024-12-01“…Furthermore, DEGs involved in lipid metabolism and branch-chain amino acid degradation pathways exhibited surge in expression at mid-fattening vs. weaning, with acetyl-CoA and branched-chain-CoA as intermediates, and driven by regulation of PPAR and AMPK signaling pathways. Overall, our findings provided novel insight into the critical time window and pivotal candidate genes of OFA synthesis in the adipose tissue, which will assist with the targeted development of nutritional strategies to inhibit OFA accumulation of lambs.…”
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1571
Female mice lacking GluA3 show early onset of hearing loss, cochlear synaptopathy, and afferent terminal swellings in ambient sound levels
Published 2025-02-01“…Summary: AMPA-type glutamate receptors (AMPARs) mediate excitatory cochlear transmission. …”
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1572
New therapies in pulmonary arterial hypertension: Recent insights
Published 2025-03-01“…This is a review of recent advances in the development of innovative therapeutic strategies for PAH.The first section of this paper explores approaches targeting TGF-β signalling, both acting directly on receptors through drugs like Sotatercept and exogenous BMP9, and indirectly, inhibiting the degradation of key receptors, such as BMPR2. …”
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1573
Validation and the role of PDK4 relevant to ferroptosis in degenerative lumbar disc disease
Published 2025-01-01“…KEGG pathway analysis showed that these genes were mainly involved in Parkinson’s disease, oxytocin signaling pathway, calcium ion signaling pathway, AMPK signaling pathway, and glucagon signaling pathway. …”
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1574
Mechanisms of Herbal Nephroprotection in diabetes mellitus
Published 2020-01-01“…Special attention was given to the various pathways involved, pointing out the ability of the phytoagents to hinder the deleterious ones (especially those leading to, driven by, or associated with TGF-β activation, SREBP, Smad, MAPK, PKC, NF-κB, NLRP3 inflammasome, and caspase), to promote the protective ones (PPAR-α, PPAR-γ, EP4/Gs/AC/cAMP, Nrf2, AMPK, and SIRT1), and to favorably modulate those with potentially dual effect (PI3K/Akt). …”
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1575
二甲双胍改善多囊卵巢综合征大鼠胰岛素敏感性的机制
Published 2014-01-01“…【结论】 二甲双胍改善PCOS 大鼠胰岛素抵抗和肝脏脂肪沉积,可能与其激活肝脏组织AMPK通路和降低内质网应激水平有关?…”
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1576
Chinese Herbal Medicine in Ameliorating Diabetic Kidney Disease via Activating Autophagy
Published 2019-01-01“…In this review, we briefly summarize underlying mechanisms of autophagy dysregulation in DKD, including AMP-activated protein kinase (AMPK), the mechanistic target of rapamycin (mTOR), and the sirtuin (Sirt) pathways, and we particularly concentrate on the current status of Chinese herbal medicine treating DKD by regulating autophagy. …”
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Genetic epidemiology of Plasmid Mediated Class C Beta-Lactamase among Enterobacteriaceae isolates
Published 2024-05-01“…Conclusions: These findings provide evidence-based of highly spreading and diversified distribution of transferable AmpC among Enterobacteriaceae in two Asia-Pacific countries. …”
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1579
Ginsenoside Rh2 regulates triple-negative breast cancer proliferation and apoptosis via the IL-6/JAK2/STAT3 pathway
Published 2025-01-01“…The ability of ginsenoside Rh2 to inhibit TNBC cell proliferation was further confirmed by attenuating the activation of the IL-6/JAK2/STAT3 apoptosis pathway and reducing the expression of protein kinases AMPK-α1 and PKA-Cα.ConclusionBased on network analysis and experimental validation, our findings demonstrate that ginsenoside Rh2 regulates TNBC proliferation and apoptosis through suppression of the IL-6/JAK2/STAT3 pathway, both in vitro and in vivo. …”
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1580
The gut-liver axis mechanism of increased susceptibility to non-alcoholic fatty disease in female offspring rats with prenatal caffeine exposure
Published 2024-11-01“…In vivo and in vitro experiments confirmed that sodium butyrate (NaB) supplementation could reduce hepatic lipid accumulation through MCT1/GPR109A-AMPK, thereby effectively decreasing the susceptibility to NAFLD in the PCE female offspring rats.…”
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