Energy metabolism and the intestinal barrier: implications for understanding and managing intestinal diseases by Shuai Chen, Caifei Shen, Xiaorui Zeng, Luqiang Sun, Fangli Luo, Renhong Wan, Yupeng Zhang, Xinyun Chen, Yujun Hou, Wen Wang, Qianhua Zheng, Ying Li

“…Pharmacological strategies to elevate SCFA levels can activate the AMPK pathway and rectify abnormalities in energy metabolism. …”
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Fimasartan Ameliorates Nonalcoholic Fatty Liver Disease through PPARδ Regulation in Hyperlipidemic and Hypertensive Conditions by Yong-Jik Lee, Yoo-Na Jang, Yoon-Mi Han, Hyun-Min Kim, Jong-Min Jeong, Hong Seog Seo

“…Consequently, fimasartan ameliorates nonalcoholic fatty liver disease mainly through the activation of oxidative metabolism represented by PPARδ-AMPK-PGC-1α pathway.…”
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ANTHROPOCENTRIC DIMENSIONS OF UKRAINIAN CULTURE (IN THE CONTEXT OF THE ARCHETYPE OF THE WISE OLD MAN) by Z. O. Yankovska, L. V. Sorochuk

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ALDOA contributes to colorectal tumorigenesis and metastasis by targeting YAP by Liang Sun, Ting Lu, Linhua Jiang, Huihui Yao, Qixuan Xu, Jie Sun, Xiaoqin Yang, Songbing He, Xinguo Zhu

“…Mechanistically, high ALDOA expression inhibited AMP-activated protein kinase (AMPK) phosphorylation possibly through regulating cellular glycolysis or the formation of v-ATPase-regulator-AXIN/LKB1 complex, which led to Yes-associated protein (YAP) unphosphorylation and enhanced the proliferative and migratory potential of CRC cells. …”
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DIFFERENT HUMAN IMAGES AND ANTHROPOLOGICAL COLISSIONS OF POST-MODERNISM EPOСH: BIOPHILOSOPHICAL INTERPRETATION by S. К. Коstyuchkov

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Does perioperative electroacupuncture reduce postoperative pain in dogs undergoing ovariohysterectomy? by Celine Iwe, Anika Schiele, Vanessa Passenegg, Daniele Corona, Regula Bettschart-Wolfensberger, Vanessa Heitzmann

“…Three hours after surgery (T3), 89.4% and six hours postoperatively (T6), 71.4% of the dogs in both groups exceeded the analgesic intervention threshold of the mCMPS-SF, indicating the need for rescue analgesia.DiscussionThe results of the study indicate that perioperative electroacupuncture treatment did not improve postoperative pain in dogs undergoing ovariohysterectomy. …”
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ANTHROPOLOGICAL AND AXIOLOGICAL DIMENSIONS OF SOCIAL EXPECTATIONS AND THEIR INFLUENCE ON SOCIETY’S SELF-ORGANIZATION by І. M. Hoian, V. P. Budz

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Alda-1 Ameliorates Liver Ischemia-Reperfusion Injury by Activating Aldehyde Dehydrogenase 2 and Enhancing Autophagy in Mice by Meng Li, Min Xu, Jichang Li, Lili Chen, Dongwei Xu, Ying Tong, Jianjun Zhang, Hailong Wu, Xiaoni Kong, Qiang Xia

“…We further demonstrated that Alda-1 treatment could activate AMPK and autophagy and that AMPK activation was required for Alda-1-mediated autophagy enhancement. …”
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OUT-OF-BODY EXPERIENCE, PURE BEING AND METAPHYSICS by I. V. Karivets

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PHILOSOPHICAL IDEAS IN SPIRITUAL CULTURE OF THE INDIGENOUS PEOPLES OF NORTH AMERICA by S. V. Rudenko, Y. A. Sobolievskyi

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ETHICS OF LIABILITY K.-O.APELY IN THE LANDSCAPES OF CONTRACTUALISM by Dmytro V. Usov

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PHILOSOPHICAL AND SOCIOCULTURAL DIMENSIONS OF PERSONALITY PSYCHOLOGICAL SECURITY by O. Y. Blynova, L. S. Holovkova, O. V. Sheviakov

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Evaluating the reflux suppression properties of Gaviscon Infant powder with different milk formulations using an in vitro model of the infant stomach by Fiona McLaughlin, Jeanine Fisher, Mark Atherton, Cathal Coyle

“…Abstract Gastroesophageal reflux (GER) is common in babies and infants and is characterized by effortless regurgitation (with or without vomiting), which is a common symptom of other infant conditions, including cow’s milk protein allergy (CMPA). Various milk formulations are commercially available to help manage GER and CMPA symptoms (extensively hydrolyzed [eHF], partially hydrolyzed [pHF], and amino-acid formulas [AAF]). …”
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PHILOSOPHICAL AND PSYCHOLOGICAL DIMENSIONS OF SOCIAL EXPECTATIONS OF PERSONALITY by V. V. Khmil, I. S. Popovych

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Alpha Lipoic Acid Modulated High Glucose-Induced Rat Mesangial Cell Dysfunction via mTOR/p70S6K/4E-BP1 Pathway by Chuan Lv, Can Wu, Yue-hong Zhou, Ying Shao, Guan Wang, Qiu-yue Wang

“…Conversely, LA at a higher concentration (1.0 mmol/L) inhibited high glucose-induced rat mesangial cell proliferation, entry of cell cycle into S phase, and extracellular matrix exertion, as well as phosphorylation of mTOR, p70S6K, and 4E-BP1 but enhanced the activity of AMPK. However, these effects disappeared when AMPK activity was inhibited with CaMKK inhibitor STO-609. …”
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ANTHROPOLOGICAL SPHERE OF HUMAN EXISTENCE: RESTRICTIONS ON HUMAN RIGHTS DURING PANDEMIC THREATS by V. S. Blikhar, I. M. Zharovska

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CIVILIZATIONAL AND INSTITUTIONAL ASPECTS OF NATIONAL SELF-IDENTIFICATION IN UKRAINE: PHILOSOPHICAL-ANTHROPOLOGICAL APPROACH by M. I. Boichenko, O. V. Yakovleva, V. V. Liakh

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A Citrus bergamia Extract Decreases Adipogenesis and Increases Lipolysis by Modulating PPAR Levels in Mesenchymal Stem Cells from Human Adipose Tissue by Debora Lo Furno, Adriana Carol Eleonora Graziano, Rosanna Avola, Rosario Giuffrida, Vincenzo Perciavalle, Francesco Bonina, Giuliana Mannino, Venera Cardile

“…Moreover, the expression of peroxisome proliferator-activated receptor gamma (PPAR-γ), adipocytes fatty acid-binding protein (A-FABP), adipose triglyceride lipase (ATGL), hormone-sensitive lipase (HSL), monoglyceride lipase (MGL), 5′-adenosine monophosphate-activated protein kinase (AMPK)α1/2, and pAMPKα1/2 was evaluated by Western blot analysis and the release of glycerol by colorimetric assay. …”
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ROMANTIC HUMAN STUDY: PECULIARITIES OF PERSONALITY PHILOSOPHY IN THE LITERATURE OF THE 1820-1830-IES. by T. N. Zhuzhgina-Allahverdian, S. A. Ostapenko

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SOCIO-CULTURAL AND PHILOSOPHICAL-LEGAL DIMENSIONS OF THE GENDER IDENTITY PROBLEM by V. S. Blikhar, I. M. Zharovska, I. O. Lychenko

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