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    Diet restriction and exercise alleviate cognitive reduction of high fat diet (HFD)-induced obese mice by rescuing inflammation-mediated compromised insulin signaling pathway through activating AMPK/SIRT1 signal pathway and suppressing TLR4 signal pathway by Hu Zhang, Ye Zhang, Jiling Liang, Jiahang Li, Miao He, Xin Liu, Jielun Huang, Minghui Wang, Jingjing Fan, Ning Chen

    Published 2024-11-01
    “…In contrast, aerobic exercise, high-intensity intermittent exercise, regular diet, and intermittent fasting could inhibit apoptosis caused by inflammation-mediated compromised insulin signaling pathway in hippocampal tissues through activating the AMPK/SIRT1 signal pathway and suppressing the TLR4 signal pathway, thereby rescuing the cognitive impairment of obese mice. …”
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    LIPS and PaO2/FiO2 Combined Plasma Biomarkers Predict Onset of Acute Respiratory Distress Syndrome in Patients of High Risks in SICU: A Prospective Exploratory Study by Ziyuan Shen, Zhongnan Yin, Senhao Wei, Zhukai Cong, Feng Zhao, Hua Zhang, Xi Zhu

    Published 2024-01-01
    “…We constructed a nomogram that had the ability to predict ARDS in patients of high risks in SICU. Conclusions. LIPS, PaO2/FiO2, plasma IL-8, and RAGE of the first day were independent risk factors of the onset of ARDS. …”
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