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Beyond consciousness: Ethical, legal, and social issues in human brain organoid research and application
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The Effects of Early-Life Predator Stress on Anxiety- and Depression-Like Behaviors of Adult Rats
Published 2014-01-01“…Childhood emotional trauma contributes significantly to certain psychopathologies, such as post-traumatic stress disorder. In experimental animals, however, whether or not early-life stress results in behavioral abnormalities in adult animals still remains controversial. …”
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Metagenomic Insights into Pigeon Gut Microbiota Characteristics and Antibiotic-Resistant Genes
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Blood transcriptome resources of chinstrap () and gentoo () penguins from the South Shetland Islands, Antarctica
Published 2019-03-01“…Functional gene annotations through pathway analyses of the Gene Ontology, EuKaryotic Orthologous Groups, and Kyoto Encyclopedia of Genes and Genomes (KEGG) databases were performed for each blood transcriptome, resulting in a similar compositional order between the two transcriptomes. …”
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Spatiotemporal variations in integrated trophic positions of stream macroinvertebrate communities
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Interleukin-6 related signaling pathways as the intersection between chronic diseases and sepsis
Published 2025-01-01“…IL-6 related signaling pathways were sought in Kyoto Encyclopedia of Genes and Genomes (KEGG), and retrieved protein-protein interaction in the Search for Interaction Genes tool (STRING). …”
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Identification of markers correlating with mitochondrial function in myocardial infarction by bioinformatics.
Published 2024-01-01“…Differentially expressed genes (DEGs) in the dataset were screened by ClusterGVis, Weighted Gene Co-Expression Network Analysis (WGCNA) and GEO2R, and functional enrichment was performed by Gene Set Enrichment Analysis (GSEA) and Kyoto Encyclopedia of Genomes (KEGG). Then mitochondria-associated DEGs (MitoDEGs) were obtained. …”
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Determining the Potential Roles of Branched-Chain Amino Acids in the Regulation of Muscle Growth in Common Carp (Cyprinus carpio) Based on Transcriptome and MicroRNA Sequencing
Published 2023-01-01“…Based on their expression profiles, 2,146 differentially expressed genes (DEGs) and 84 differentially expressed miRNA (DEMs) were evaluated. Kyoto Encyclopedia of Genes and Genome pathways, including the proteasome, phagosome, autophagy in animals, proteasome activator complex, and ubiquitin-dependent protein catabolic process, were enriched for these DEGs and DEMs. …”
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Identification of important genes related to ferroptosis in early missed abortion based on WGCNA
Published 2025-01-01“…Findings from gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses indicate a correlation between iron- DEFRGS in key modules and the p53 signaling, mitophagy-animal, and protein digestion and absorption pathways. …”
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Comprehensive bioinformatics analysis identifies metabolic and immune-related diagnostic biomarkers shared between diabetes and COPD using multi-omics and machine learning
Published 2025-01-01“…Through cross-analysis, we identified the shared DEGs of COPD and diabetes, and investigated alterations of signaling pathways using Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG), and gene set enrichment analysis (GSEA). …”
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Protective effect and mechanism of Sufentanil on acute lung injury in septic mice
Published 2025-01-01“…To this end, a protein-protein interaction (PPI) network for common targets was first constructed with Swiss Target Prediction Database, GeneCards Database, Draw Venn Diagram Software, STRING 11.5 Database, Cytoscape 3.10.0 Software and Metascape Database, and then key targets were subject to enrichment analysis by Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) to obtain the key targets of Sufentanil for the treatment of pulmonary sepsis, and then verified by animal experiments. …”
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Transcriptome analysis of jejunal mucosal tissue in breeder hens exposed to acute heat stress
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Developmental Proteomics Reveals the Dynamic Expression Profile of Global Proteins of <i>Haemaphysalis longicornis</i> (Parthenogenesis)
Published 2025-01-01“…<i>H. longicornis</i> is used as an experimental animal model for the study of three-host ticks due to its special life cycle and easy maintenance in the laboratory and in its reproduction. …”
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Disorders of the central nervous system cognitive and mnestic functions in genetic arterial hypertension and with the use of beta-blockers of different generations
Published 2024-09-01“…The study used 40 male rats weighing 280–300 g with spontaneous arterial hypertension (SHR) aged 8 months and 10 normotensive control normotensive Wistar–Kyoto rats (WKR) weighing 200–220 g. The animals were divided into 5 experimental groups of 10 rats each. …”
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