Risk of hepatocellular carcinoma in Asian patients with primary biliary cholangitis: A nationwide and hospital cohort study by Jihye Lim, Ye-Jee Kim, Sehee Kim, Jonggi Choi

“…Methods: The data of 4,882 patients with PBC and 38,603 matched controls were extracted from the Korean National Health Insurance Service (2007–2020) and analyzed. …”
Get full text

Identification and characterization of 17 novel polynucleotide microsatellite markers in Ocypode stimpsoni (Decapoda: Ocypodidae) by Ha Yeun Song, Young Ji Choi, Dea-Sung Lee, Hyun Ki Choi, Kyung Min Choi, Kang-Yeol Yu, Namki Cho, Seungki Lee

Get full text

Long-term trends in the prevalence of cardiovascular-kidney-metabolic syndrome in South Korea, 2011–2021: a representative longitudinal serial studyResearch in context by Yesol Yim, Jae E. Lee, Yejun Son, Soeun Kim, Hojae Lee, Sooji Lee, Wonwoo Jang, Hanseul Cho, Hayeon Lee, Kyeongmin Lee, Hyesu Jo, Jaeyu Park, Jiyeon Oh, Louis Jacob, Jiseung Kang, Hyunji Sang, Sang Youl Rhee, Dong Keon Yon

“…However, this syndrome has not been studied extensively outside of the United States. Thus, this study aimed to examine the long-term trends in CKM syndrome and its associated demographic features in South Korea. …”
Get full text

A Pharmacokinetic/Pharmacodynamic Study of Esomeprazole Comparing a Dual Delayed-Release Formulation (YYD601) to a Conventional Formulation Following Multiple Administrations in He... by Lee HW, Kang WY, Park JS, Lee JH, Park JJ, Gwon MR, Yoon YR, Seong SJ

“…Hae Won Lee,1 Woo Youl Kang,2 Ji Seo Park,1 Jae Hwa Lee,1 Jin Ju Park,1 Mi-Ri Gwon,1 Young-Ran Yoon,1 Sook Jin Seong1 1School of Medicine, Kyungpook National University and Department of Clinical Pharmacology and Therapeutics, Kyungpook National University Hospital, Daegu, 41944, Republic of Korea; 2Clinical Trial Dossier Evaluation Team, Innovative Products Support Department, National Institute of Food and Drug Safety Evaluation, Cheongju, 28159, Republic of KoreaCorrespondence: Young-Ran Yoon, Professor, School of Medicine, Kyungpook National University and Department of Clinical Pharmacology and Therapeutics, Kyungpook National University Hospital, 130 Dongdeok-Ro, Jung-gu, Daegu, 41944, Republic of Korea, Tel +82-53-420-4950, +82-53-420-5218, Email yry@knu.ac.kr Sook Jin Seong, Clinical Associate Professor, School of Medicine, Kyungpook National University and Department of Clinical Pharmacology and Therapeutics, Kyungpook National University Hospital, 130 Dongduk-Ro, Jung-gu, Daegu, 41944, Republic of Korea, Tel +82-53-200-6351, +82-53-420-5218, Email wintersj@knu.ac.krBackground: YYD601 is a new dual delayed-release formulation of esomeprazole, developed to enhance plasma exposure and prolong the duration of acid suppression.Purpose: This study aimed to evaluate the safety, pharmacokinetic (PK), and pharmacodynamic (PD) profiles of YYD601 20 mg following single and multiple oral administrations in healthy, fasting adult Koreans, and to compare these outcomes to those of the conventional esomeprazole 20 mg capsule.Methods: A randomized, open-label, two-period crossover study was conducted in 28 participants, who were divided into two treatment groups: one group received YYD601 20 mg, and the other received conventional esomeprazole 20 mg, once daily for five consecutive days. …”
Get full text

Prediction model for type 2 diabetes mellitus and its association with mortality using machine learning in three independent cohorts from South Korea, Japan, and the UK: a model de... by Hayeon Lee, Seung Ha Hwang, Seoyoung Park, Yunjeong Choi, Sooji Lee, Jaeyu Park, Yejun Son, Hyeon Jin Kim, Soeun Kim, Jiyeon Oh, Lee Smith, Damiano Pizzol, Sang Youl Rhee, Hyunji Sang, Jinseok Lee, Dong Keon Yon

“…Summary: Background: Type 2 diabetes mellitus (T2DM) is a significant global public health concern that has steadily increased over the past few decades. Thus, this study aimed to predict the incidence of T2DM within 5 years and the risk of mortality following the onset of T2DM. …”
Get full text

Simulation of Threshold UV Exposure Time for Vitamin D Synthesis in South Korea by Sang Seo Park, Yun Gon Lee, Migyoung Kim, Jaemin Kim, Ja-Ho Koo, Chang Ki Kim, Junshik Um, Jongmin Yoon

Get full text

Distribution of the arctic variant of the CPT1A gene in indigenous populations of Siberia by B. A. Malyarchuk, M. V. Derenko, G. A. Denisova, A. N. Litvinov

Get full text

Abnormal Operation Detection of Automated Orchard Irrigation System Actuators by Power Consumption Level by Shahriar Ahmed, Md Nasim Reza, Md Rejaul Karim, Hongbin Jin, Heetae Kim, Sun-Ok Chung

Get full text

Validation of Ionospheric Specifications During Geomagnetic Storms: TEC and foF2 During the 2013 March Storm Event‐II by J. S. Shim, I.‐S. Song, G. Jee, Y.‐S. Kwak, I. Tsagouri, L. Goncharenko, J. McInerney, A. Vitt, L. Rastaetter, J. Yue, M. Chou, M. Codrescu, A. J. Coster, M. Fedrizzi, T. J. Fuller‐Rowell, A. J. Ridley, S. C. Solomon, J. B. Habarulema

Get full text

Projecting Future Climate Change Scenarios Using Three Bias-Correction Methods by Donghyuk Kum, Kyoung Jae Lim, Chun Hwa Jang, Jichul Ryu, Jae E. Yang, Seong Joon Kim, Dong Soo Kong, Younghun Jung

Get full text

Association of Frailty Index at 66 Years of Age with Health Care Costs and Utilization Over 10 Years in Korea: Retrospective Cohort Study by Jieun Jang, Anna Kim, Mingee Choi, Ellen P McCarthy, Brianne Olivieri-Mui, Chan Mi Park, Jae-Hyun Kim, Jaeyong Shin, Dae Hyun Kim

“…ObjectiveThe objective of our study was to examine the association between an individual’s frailty index at 66 years of age and their health care costs and utilization over 10 years. …”
Get full text

Inverse design of nanophotonic devices enabled by optimization algorithms and deep learning: recent achievements and future prospects by Kim Junhyeong, Kim Jae-Yong, Kim Jungmin, Hyeong Yun, Neseli Berkay, You Jong-Bum, Shim Joonsup, Shin Jonghwa, Park Hyo-Hoon, Kurt Hamza

Get full text

Time-series Spectroscopy and TESS Photometry of the Oscillating Eclipsing Algol System V389 Cassiopeiae by Pakakaew Rittipruk, Kyeongsoo Hong, Jae Woo Lee, Anirut Phriksee, Supachai Awiphan, Jae-Rim Koo, Jang-Ho Park

Get full text

Effect of EOG Signal Filtering on the Removal of Ocular Artifacts and EEG-Based Brain-Computer Interface: A Comprehensive Study by Malik M. Naeem Mannan, M. Ahmad Kamran, Shinil Kang, Myung Yung Jeong

Get full text