CD8+PD-1+ to CD4+PD-1+ ratio (PERLS) is associated with prognosis of patients with advanced NSCLC treated with PD-(L)1 blockers by Francois-Xavier Danlos, Aurélien Marabelle, Roberto Ferrara, Benjamin Besse, Lydie Cassard, Nathalie Chaput, Aude Desnoyer, Boris Duchemann, Marie Naigeon, Edouard Auclin, Jean-Mehdi Jouniaux, Lisa Boselli, Jonathan Grivel, Laura Mezquita, Caroline Caramella

“…A composite score (good, intermediate and poor) was determined using the combination of PERLS and senescent immune phenotype as previously described in aNSCLC.Results In the discovery cohort (N=75), the PERLS cut-off was 1.91, and 11% of patients were PERLS+. …”
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