Borrelia burgdorferi radiosensitivity and Mn antioxidant content: antigenic preservation and pathobiology by Andrés F. Londoño, Ajay Sharma, Jared Sealy, Vipin S. Rana, Shelby D. Foor, Vera Y. Matrosova, Elena K. Gaidamakova, Robert P. Volpe, Michael J. Daly, Brian M. Hoffman, Utpal Pal, J. Stephen Dumler

“…These observations also provide an opportunity for innovative vaccine development strategies employing ionizing radiation to disrupt the B. burgdorferi genome, while maintaining antigenic potency. These fresh insights extend our understanding of the unique biology of B. burgdorferi and open new avenues for considering novel whole-cell Lyme disease vaccines using MDP and irradiation-based inactivation.IMPORTANCEThe study highlights that electron paramagnetic resonance (EPR) spectroscopy is sufficiently sensitive to detect small differences in radiation resistance among Borrelia burgdorferi strains based on their population of Mn2+-metabolite complexes (H-Mn). …”
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Artificial intelligence-based, non-invasive assessment of the central aortic pressure in adults after operative or interventional treatment of aortic coarctation by Renate Oberhoffer, Peter Ewert, Harald Kaemmerer, Nicole Nagdyman, Oliver Dewald, Frank Klawonn, Michael Huntgeburth, Andreas Eicken, Christian Meierhofer, Sebastian Freilinger, Martin Middeke, Pinar Bambul Heck, Annika Freiberger, Frank Harig, Manuel Lösch, Fritz Mellert, Fabian von Scheidt, Elsa Ury, Nicole Wolfrum, Ann-Sophie Kaemmerer-Suleiman, Mathieu N. Suleiman

“…Comparing PBP and CABP in the entire collective, significant differences were found for CABP in relation to the procedure performed, with higher values in patients after prosthesis interposition as their last treatment (p<0.05).Conclusion AI-PWA provides valuable insights into cardiovascular stress in CoA patients, beyond PBP measurements. …”
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Delta radiomics modeling based on CTP for predicting hemorrhagic transformation after intravenous thrombolysis in acute cerebral infarction: an 8-year retrospective pilot study by Xiaxia Wu, Xiaxia Wu, Jinfang Yang, Jinfang Yang, Xianqun Ji, Yingjian Ye, Ping Song, Lina Song, Peng An, Peng An

“…Similar results were validated in the test set, and a novel nomogram was constructed to simplify the prediction process for HT-ACI.ConclusionThe combined model established based on delta radiomics from CTP may provide early insights into the hemodynamic status of acutely ischemic brain tissue, holding significant clinical importance for predicting HT-ACI. …”
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Survei Penelitian Metode Kecerdasan Buatan untuk Mendeteksi Ancaman Teknologi Serangan Siber by Eza Yolanda Fitria, Kusprasapta Mutijarsa

“…The results of this research are expected to contribute to providing new insights into the world of cybersecurity to open future research opportunities, especially for novice researchers who wish to conduct research in the field of cybersecurity. …”
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The Effect of Chewing Simulation on Flexural Strength of Different Lithium Disilicate Ceramics by Alsulimani O, Yousief SA, Al-Dabbagh RA, Attar EA, Bukhary DM, Algamaiah H, Musawa K, Subahi A, Abuzinadah SH, Alhaddad AJ, Alqahtani WMS, Emam ANM, Alqhtani MA, Elmarakby AM

“…This study can provide valuable insights for dental professionals to make informed decisions about which material is most appropriate for various clinical situations.Keywords: lithium disilicate, flexural strength, ceramics, mastication…”
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Measurement report: Analysis of aerosol optical depth variation at Zhongshan Station in Antarctica by L. Chen, L. Chen, L. Zhang, Y. She, Z. Zeng, Y. Zheng, B. Tian, W. Zhang, Z. Liu, H. Che, M. Ding

“…These findings help us infer AOD variation patterns in the coastal Antarctic based on meteorological changes, providing valuable insights for climate modeling in the context of global climate change.…”
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Study on the Synergistic Regulation Model for <i>Lycium barbarum</i> Berries Under Integrated Irrigation and Fertigation in Northwest Arid Regions by Yanlin Ma, Huile Lv, Yanbiao Wang, Yayu Wang, Minhua Yin, Yanxia Kang, Guangping Qi, Rong Zhang, Jinwen Wang, Junxian Chen

“…This study provides key insights for implementing integrated drip irrigation in northwest China’s arid regions.…”
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KiKli Fit: Investigating the Implementation of a Physical Activity Program in Pediatric Cancer by Lars Rehbein, Ann Christin Schneider, Christina Hillebrech, Christina Schindera, Amika Singh, Katharina Eva, Valentin Benzing

“…Qualitative interviews were conducted with children, parents, nurses, physiotherapists, psychologists, doctors, a sport scientist leading the PA program, and two implementation leaders to gather comprehensive, multi-perspective insights. In total 15 interviews explored attitudes, perceived barriers, facilitators, and expectations regarding implementing the PA program in the pediatric oncology setting. …”
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Associations Between Complement C4, Habitual Constipation, and Sleep Disturbance in Oldest-Old and Centenarian Chinese Adults by Sun Z, Nie Y, Pei J, Gao M, Luan Z, Zhao Y, Li Z, Fu S

“…In the multiple logistic regression models, complement C4 was negatively associated with sleep disturbance (odds ratio: 0.978, 95% CI: 0.963– 0.993, P < 0.05), and habitual constipation was positively associated with sleep disturbance (odds ratio: 1.609, 95% CI: 1.194– 2.168, P < 0.05).Conclusion: The present study provides epidemiological evidence that sleep disturbance is negatively associated with complement C4 and positively associated with habitual constipation in oldest-old and centenarian Chinese adults, which expands the knowledge for the associations between complement C4, habitual constipation, and sleep disturbance in the elderly population and provides new insights and pathways on the treatment of sleep disturbance by regulating immune factors and intestinal function.Keywords: centenarian, complement C4, habitual constipation, oldest-old, sleep disturbance…”
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Prevalence of common diarrheagenic enterobacteriaceae in Iran (2000–2023): a systematic review and meta-analysis by Mozhgan Derakhshan-Sefidi, Fereshteh Eidy, Somayyeh Nadi-Ravandi, Sareh Bagheri-Josheghani, Maryam Mirfakhraei

“…Conclusion This meta-analysis provides valuable insights into the prevalence of diarrheagenic Enterobacteriaceae in Iran over the past two decades. …”
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Identification of the Granule-Bound Starch Synthase (GBSS) Genes Involved in Amylose Biosynthesis in Tartary Buckwheat (<i>Fagopyrum tataricum</i> (L.) Gaertn.) by Juan Huang, Fei Liu, Jieqiong Zhang, Bin Tang, Jiao Deng, Taoxiong Shi, Liwei Zhu, Hongyou Li, Qingfu Chen

“…Overall, this research not only deepens our understanding of the molecular mechanisms of amylose synthesis in Tartary buckwheat, but also provides scientific insights for enhancing crop amylose content and quality through molecular breeding.…”
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Technical note: Towards atmospheric compound identification in chemical ionization mass spectrometry with pesticide standards and machine learning by F. Bortolussi, H. Sandström, F. Partovi, F. Partovi, J. Mikkilä, P. Rinke, P. Rinke, P. Rinke, P. Rinke, M. Rissanen, M. Rissanen

“…In this study, we apply machine learning to a reference dataset of pesticides in two standard solutions to build a model that can provide insights from CIMS analyses in atmospheric science. …”
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Dealing with Complexity – Knowledge, design, and management of the built environment by Cesare Sposito, Francesca Scalisi

“…The articles published in issue 16 of AGATHÓN offer valuable insights into addressing the complex issues surrounding the knowledge, design, and management of the built environment in light of the increasingly urgent pragmatic indicators of environmental, social, and economic sustainability, demonstrating that the complexity of the built environment, rather than being a challenge, can become an opportunity to advance the achievement of the 17 Sustainable Development Goals. …”
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Elliptic and Quadrangular Flow of Protons in the High-Baryon-Density Region by Shaowei Lan, Zuowen Liu, Like Liu, Shusu Shi

“…The collective flow provides valuable insights into the anisotropic expansion of particles produced in heavy-ion collisions and is sensitive to the equation of the state of nuclear matter in high-baryon-density regions. …”
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Geometric Feature Characterization of Apple Trees from 3D LiDAR Point Cloud Data by Md Rejaul Karim, Shahriar Ahmed, Md Nasim Reza, Kyu-Ho Lee, Joonjea Sung, Sun-Ok Chung

“…The results are based on a limited dataset of six measured values, providing initial insights into geometric feature characterization performance. …”
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MSC-exosomes pretreated by Danshensu extracts pretreating to target the hsa-miR-27a-5p and STAT3-SHANK2 to enhanced antifibrotic therapy by Jiabin Liang, Jingxiu Zhao, Lin Yang, Qian Wang, Jing Liao, Jianhao Li, Weizhao Zhuang, Fanghong Li, Jinxian He, Yukuan Tang, Hanwei Chen, Chen Huang

“…In vivo experiments were conducted on a PF mouse model to observe cell morphology, collagen deposition, fibrosis localization, and to evaluate peritoneal functions such as filtration rate, urea nitrogen clearance, peritoneal thickness, and protein leakage. Mechanistic insights were gained through the analysis of the STAT3/HIF-1α/VEGF signaling pathway, tissue dual-fluorescence localization,chromatin immunoprecipitation sequencing (ChIP-seq), and dual-luciferase reporter (DLR) assays. …”
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Nature and prevalence of long-term conditions in people with intellectual disability: retrospective longitudinal population-based study by Ashley Akbari, Navjot Kaur, Rania Kousovista, Gemma Lewin, Emeka Abakasanga, Rishika Shivamurthy, Georgina Cosma, Gyuchan Jun, Satheesh Gangadharan

“…Further work is required to translate the findings of this study into actionable insights. Clusters of multiple long-term conditions, trajectories, outcomes and risk factors should be explored to optimise the understanding and longitudinal care of individuals with intellectual disabilities and long-term conditions.…”
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Evaluation of Healthcare Outcomes of Patients Treated with 3D-Printed-Titanium and PEEK Cages During Fusion Procedures in the Lumbar Spine by Corso KA, Teferra AA, Michielli A, Corrado K, Marcini A, Lotito M, Smith C, Costa M, Ruppenkamp J, Wallace A

“…The mean costs per patient associated with reoperation and revision for the entire cohort were &dollar;220 and &dollar;1228 for PEEK and &dollar;290 and &dollar;1754 for 3D-printed-titanium.Conclusion: This study provides real-world economic insights into an area where practice data are sparse, within hospital settings for PEEK and 3D-printed-titanium spinal cages. …”
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CAMELS-IND: hydrometeorological time series and catchment attributes for 228 catchments in Peninsular India by N. K. Mangukiya, K. B. Kumar, P. Dey, S. Sharma, V. Bejagam, P. P. Mujumdar, P. P. Mujumdar, A. Sharma, A. Sharma

“…We envision that CAMELS-IND will provide a strong foundation for a community-led effort toward gaining new hydrological insights from hydrologically distinct Indian catchments and solving pertinent issues related to water management, quantification and risk assessment of hydrologic extremes, unraveling regional-scale hydrologic functioning, and climate change impact assessment of catchments across India. …”
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Digital Home-Based Self-Monitoring System for People with Heart Failure: Protocol for Development of SmartHeart and Evaluation of Feasibility and Acceptability by Ralph Maddison, Rebecca Nourse, Reza Daryabeygikhotbehsara, Teketo Kassaw Tegegne, Paul Jansons, Jonathan Charles Rawstorn, John Atherton, Andrea Driscoll, Brian Oldenburg, Rajesh Vasa, Vassilis Kostakos, Tilman Dingler, Gavin Abbott, Paul Scuffham, Jo-Anne Elizabeth Manski-Nankervis, Dominika Kwasnicka, Finn Kensing, Sheikh Mohammed Shariful Islam, Anthony Maeder, Yuxin Zhang

“…These data are processed and analyzed to provide personalized health insights, self-care support, and alerts in case of health deterioration. …”
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