Spatiotemporal evolution and driving force analysis of drought characteristics in the Yellow River Basin by Meiying Wang, Yangbo Chen, Jingyu Li, Yanjun Zhao

“…This research provides crucial insights for effective water resource management and drought mitigation strategies in the Yellow River Basin.…”
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The impact of Covid-19 on harm reduction policies in Iran: an interrupted time series analysis by Siavash Beiranvand, Meysam Behzadifar, Aidin Aryankhesal, Seyed Jafar Ehsanzadeh, Masoud Behzadifar

“…Aim The study aims to assess the impact of the Covid-19 pandemic on harm reduction services in Iran and provide evidence-based insights for policy adjustments. Using Interrupted Time Series Analysis (ITSA), the research analyzes trends in the distribution of condoms, syringes, and methadone before and after the official declaration of the pandemic in February 2020. …”
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Environmental and health risk assessment of polycyclic aromatic hydrocarbons and toxic elements in the red sea using Monte Carlo simulation by F. Alshaima Sayed, Mohamed Hamdy Eid, Ahmed M. El-Sherbeeny, Gouda Ismail Abdel-Gawad, Essam A. Mohamed, Mostafa R. Abukhadra

“…In light of these results, urgent and comprehensive water treatment measures are imperative to mitigate carcinogenic and non-carcinogenic health risks. These insights provide a foundation for implementing targeted management strategies to effectively address the challenges of heavy metal contamination in the Red Sea.…”
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Exploring the role of inflammatory biomarkers in trigeminal neuralgia by Shenglong Lai, Haiyang Li, Yazhou Xing, Du Wu, Lin Wang, Qinghua Liang

“…These findings provide novel insights into TN's inflammatory mechanisms, suggesting new avenues for targeted interventions.…”
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Elocalcitol, a fluorinated vitamin D derivative, prevents high-fat diet-induced obesity via SCAP downregulation and miR-146a-associated mechanisms by Monika Jürgenson, Keerthana Chithanathan, Aivar Orav, Külli Jaako, Janeli Viil, Mithu Guha, Kalev Kask, Alexander Zharkovsky

“…These findings provide valuable insights into the anti-obesity mechanisms of fluorinated D-vitamin analogs and suggest potential therapeutic strategies for obesity prevention.…”
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Prognostic value of serum inflammatory markers in patients with esophageal squamous cell carcinoma undergoing surgery: a two-center retrospective cohort study by Yaqin Dong, Fan Wang, Jiaying Deng, Tong Tong, Xiangxun Chen, Liming Wu, Yichun Wang, Mei Kang, Yutong Xu, Guangjie Shi, Liyang Zhu

“…Conclusions Serving as systemic inflammatory biomarkers, the neutrophil-platelet score and prognostic nutritional index offer valuable prognostic insights for patients with esophageal cancer, augmenting predictive capabilities.…”
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Targeted inhibition of Aurora kinase A promotes immune checkpoint inhibition efficacy in human papillomavirus-driven cancers by Pragya Sinha, Faye M Johnson, Soma Ghosh, Jagannadha K Sastry, Madison P O'Hara, Tuhina Mazumdar, Lacin Yapindi

“…These findings offer insights into the synergistic effects of Aurora A inhibition and ICIs and argue for further investigation and optimization of this combination approach in HPV-driven cancers.…”
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MSCs with upregulated lipid metabolism block hematopoietic stem cell differentiation via exosomal CTP-1A in MDS by Chunlai Yin, Xue Yan, Jinyi Ren, Cheng Zhang, Jiaqing Liu, Zilong Wang, Jing Liu, Weiping Li, Xia Li

“…These findings provide novel insights into MDS MSCs-metabolism-Exosome axis in ineffective hematopoiesis and offer new strategies for the treatment of MDS.…”
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Increasing vulnerability of an endemic Mediterranean-climate conifer to changing climate and fire regime by Frank W. Davis, Anne-Marie Parkinson, Max A. Moritz, Max A. Moritz, Isaac W. Park, Carla M. D’Antonio

“…Our analysis contributes several important new insights: (1) topoclimatic habitat for BDF could shrink by 19–57% by mid-century, especially for southernmost populations; (2) by mid-century, wildfire probability could increase 2–4 fold in BDF habitat, potentially diminishing the value of mid-to-high elevation sites as topoclimatic refugia; (3) CLO could play a diminishing role in providing refuge from severe wildfires as soon as mid-century but especially by end-of-century; (4) extensive areas of stable mid-century and late-century habitat are confined to national forests in the San Gabriel Mountains and Transverse Ranges. …”
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Identification of cancer cell-intrinsic biomarkers associated with tumor progression and characterization of SFTA3 as a tumor suppressor in lung adenocarcinomas by Yu Zhao, Chengcheng Zhou, Ling Zuo, Haoming Yan, Yuhan Gu, Hong Liu, Guiping Yu, Xiaorong Zhou

“…Additionally, our findings offer new insights into the mechanisms underlying LUAD tumorigenesis and immune evasion.…”
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Exploring how graft length shapes root system architecture and morphology in grapevine rootstocks by Mathieu Larrey, Jean-Pascal Tandonnet, Clément Saint Cast, Sarah Jane Cookson, Philippe Vivin

“…Overall, this study emphasizes the significance of considering rootstock length and RSA in viticultural practices. The insights gathered here contribute to a deeper understanding of the mechanisms governing root development in grafted grapevines, thereby informing strategies to enhance grafting techniques and optimize grapevine cultivation. …”
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Yunvjian decoction attenuates lipopolysaccharide-induced acute lung injury by inhibiting NF-κB/NLRP3 pathway and pyroptosis by Fanxuan Zhang, Fang Wang, Lisha Zhao, Leqian Wang, Wenjing Li, Feihua Huang, Feihua Huang, Nani Wang, Nani Wang

“…Our findings provide novel insights into the therapeutic effects of YNJ on ALI.…”
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The Global Burden of Polycystic Ovary Syndrome in Women of Reproductive Age: Findings from the GBD 2019 Study by Jiang B

“…This aims to furnish critical insights for future health policy development and adjustments in the realm of female endocrine and metabolic health.Patients and Methods: This study employed the Global Health Data Exchange to obtain PCOS burden data based on GBD 2019. …”
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Plasmodium falciparum genetic diversity and multiplicity of infection based on msp‑1, msp‑2, glurp and microsatellite genetic markers in sub-Saharan Africa: a systematic review and... by Mwesigwa, Alex, Ocan, Moses, Musinguzi, Benson, Nante, Rachel Wangi, Nankabirwa, Joaniter I., Kiwuwa, Steven M., Kinengyere, Alison Annet, Castelnuovo, Barbara, Karamagi, Charles, Obuku, Ekwaro A., Nsobya, Samuel L., Mbulaiteye, Sam M., Byakika‐Kibwika, Pauline

“…The systematic review aimed to evaluate their influence on malaria transmission dynamics and offer insights for enhancing malaria control measures in SSA. …”
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Integrated physiological and transcriptomic analysis uncovers the mechanism of moderate nitrogen application on promoting the growth and (-)-borneol accumulation of Blumea balsamif... by Yuan Yuan, Wei-Jie Tang, Wei-Jie Tang, Jia-Yuan Cao, Ke Zhong, Ke Zhong, Ze-Jun Mo, Ying Zhou, Yu-Xin Pang, Yu-Xin Pang

“…These findings provide a comprehensive understanding of the relationship between N nutrition and (-)-borneol yield in B. balsamifera, offering valuable insights for future cultivation practices.…”
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Spectroscopic analysis (UV-VIS-NIR) for predictive modeling of macro and micronutrients in grapevine leaves by J.I. Manzano, M. Rodríguez-Febereiro, M. Fandiño, M. Vilanova, J.J. Cancela

“…The objective of this study is to ascertain the viability of wide range spectrum (190–2600 nm) spectroscopy in providing precise insights into the nutritional status of vines. Our investigation specifically targets on the determination of C, N, P, K, Ca, Mg, B, Cu, Fe, Mn, Zn, Na, and Al in vine leaves from different wine growing areas, varieties and harvest years. …”
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Functional status, lymphocyte-to-monocyte ratio, and platelet-to-lymphocyte ratio as prognostic factors of one-year survival rate in elderly patients with advanced-stage non-small... by Ratna Nurhayati, Aulia Rizka, Cleopas Martin Rumende, Noorwati Sutandyo, Arif Hanafi, Edy Rizal Wahyudi, Hamzah Shatri, Anna Mira Lubis, Em Yunir, Muhammad Firdaus, Yuniar Harris Prayitno, Nadira Nibras Taqiyya

“…Conclusion: The lymphocyte-to-monocyte ratio and platelet-to-lymphocyte ratio provide significant prognostic insights regarding 1-year survival in elderly patients diagnosed with stage IIIB-IV non-small cell lung cancer (NSCLC). …”
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Evaluating the Effectiveness of Cyclin-Dependent Kinase 4/6 Inhibitors in Early- and Very Early-Onset Metastatic Breast Cancer: A Multicenter Study by Akif Doğan, Nurullah İlhan, Goncagül Akdağ, Sedat Yıldırım, Mustafa Seyyar, Zeynep Yüksel Yaşar, Hande Nur Erölmez, Heves Sürmeli, Buğra Öztosun, Özlem Nuray Sever, Hatice Odabaş, Mahmut Emre Yıldırım, Devrim Çabuk, Nedim Turan, Mahmut Gümüş

“…<i>Conclusions</i>: This study is the first to focus specifically on the treatment of early-onset breast cancer with CDK4/6 inhibitors, providing critical insights into the unique challenges faced by this patient population. …”
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Core microbe Bifidobacterium in the hindgut of calves improves the growth phenotype of young hosts by regulating microbial functions and host metabolism by Yimin Zhuang, Duo Gao, Wen Jiang, Yiming Xu, Guanglei Liu, Guobin Hou, Tianyu Chen, Shangru Li, Siyuan Zhang, Shuai Liu, Jingjun Wang, Jianxin Xiao, Mengmeng Li, Wei Wang, Shengli Li, Zhijun Cao

“…This study enhances our comprehension of how gut core microbe shapes the host phenotype and provides new insights into the manipulation of beneficial gut colonizers to improve the growth performance and productivity of young ruminants. …”
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Assessment of upper respiratory and gut bacterial microbiomes during COVID-19 infection in adults: potential aerodigestive transmission by Hafez Al-Momani, Andrew Nelson, Hadeel Al Balawi, Dua’a Al Balawi, Iman Aolymat, Ashraf I. Khasawneh, Hala Tabl, Ayman Alsheikh, AbdelRahman M. Zueter, Jeffrey Pearson, Christopher Ward

“…Such studies would benefit from the insights provided by biological samples which reflect the continuum of the aerodigestive tract.…”
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