Systematic Review with Network Meta-Analysis: Comparative Efficacy and Safety of Combination Therapy with Angiotensin II Receptor Blockers and Amlodipine in Asian Hypertensive Pati... by Dae Wook Lee, Mira Jung, Hye Won Wang, Zainah Khan, Philippe Pinton

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Treatment patterns and clinical profile in progressive pulmonary fibrosis: a Japanese cross-sectional survey by Hidekata Yasuoka, Yuko Waseda, Yuko Kaneko, Masateru Okazaki, Ryoko Iwasaki, Shoko Nagata, Mark Small, Haruyuki Ishii

“…As reported by patients themselves (n = 53), 49.1% never and 37.7% rarely missed a dose.ConclusionThis analysis of real-world data from Japan provides insights into the clinical profile of patients with IPF and PPF in Japan, and highlights differences between physicians and patients in perception of symptom severity and attitudes to treatment.…”
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Impact of Initial Heart Rate, Diastolic Pressure, and Pulse Pressure on Prognostic Outcomes in Heart Failure Patients with Mildly Reduced Ejection Fraction by Hu H, Liu Z, Zeng J, Jiang M

“…These findings provide valuable insights for risk stratification and may guide personalized management of HFmrEF patients.Keywords: heart failure with mildly reduced ejection fraction (HFmrEF), initial heart rate, diastolic pressure, pulse pressure, decision tree classification…”
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Machine Learning–Based Risk Factor Analysis and Prediction Model Construction for the Occurrence of Chronic Heart Failure: Health Ecologic Study by Qian Xu, Xue Cai, Ruicong Yu, Yueyue Zheng, Guanjie Chen, Hui Sun, Tianyun Gao, Cuirong Xu, Jing Sun

“…ConclusionsThis study offered insights into CHF risk prediction. Future research should focus on prospective studies, diverse data, advanced techniques, longitudinal studies, and exploring factor interactions for better CHF prevention and management.…”
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Efficient virtual machine placement in cloud computing environment using BSO-ANN based hybrid technique by Pradeep Singh Rawat, Sachin Gaur, Varun Barthwal, Punti Gupta, Debjani Ghosh, Deepak Gupta, Joel JP C. Rodrigues

“…It combines human ingenuity with data-driven insights to adapt to the ever-changing dynamics of cloud workloads. …”
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Application of Patient-Generated Health Data Among Older Adults With Cancer: Scoping Review by Yesol Kim, Geonah Kim, Hyeonmi Cho, Yeonju Kim, Mona Choi

“…Therefore, our findings may provide valuable insights into PGHD that health care providers and researchers can use for geriatric cancer care. …”
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Effectiveness of eHealth literacy interventions: a systematic review and meta-analysis of experimental studies by Chiara Barbati, Elvira Maranesi, Cinzia Giammarchi, Matteo Lenge, Manila Bonciani, Elisa Barbi, Giacomo Pietro Vigezzi, Mauro Dragoni, Tania Bailoni, Anna Odone, Roberta Bevilacqua

“…Conclusions Our findings support the effectiveness of tailored interventions in significantly enhancing eHL, providing key insights for evidence-based intervention design targeted to different population groups.…”
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Exploring Self-Management Behavior Profiles in Patients with Multimorbidity: A Sequential, Explanatory Mixed-Methods Study by Fu Y, Wu J, Guo Z, Shi Y, Zhao B, Yu J, Chen D, Wu Q, Xue E, Du H, Zhang H, Shao J

“…The integrated results highlighted distinct characteristics: Symptom-driven Profile patients exhibited reactive behaviors with limited health awareness, Passive-engagement Profile patients reduced engagement once symptoms stabilized, while Active-cooperation Profile patients proactively managed their conditions.Conclusion: Identifying three distinct self-management behavior profiles and their relationship with workload and capacity provides valuable insights into multimorbid patients’ experiences, emphasizing the need for tailored interventions targeting workload and capacity to improve health outcomes.Keywords: multimorbidity, self-management, workload, capacity, interaction, mixed-methods study…”
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Comprehensive pan-cancer analysis reveals NTN1 as an immune infiltrate risk factor and its potential prognostic value in SKCM by Fuxiang Luan, Yuying Cui, Ruizhe Huang, Zhuojie Yang, Shishi Qiao

“…This comprehensive analysis provides insights into its potential implications in pan-cancer research.…”
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Enhancing ethical self-efficacy among dementia caregiver staff: A mixed-methods feasibility study of the care programme by Sigurd Lauridsen, Sofie Smedegaard Skov, Lucca-Mathilde Thorup, Marie-Eva Berg, Anna Paldam Folker, Peter Simonsen, Frederik Schou-Juul

“…Conclusion: The quantitative results indicate high levels of satisfaction and relevance, with the majority of participants believing that the program improves care and enhances their ability to manage ethical issues. Qualitative insights further emphasize the program's success in meeting the need for ethics training, facilitated by external researchers and cross-institutional collaboration. …”
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Digital Gaming and Subsequent Health and Well-Being Among Older Adults: Longitudinal Outcome-Wide Analysis by Atsushi Nakagomi, Kazushige Ide, Katsunori Kondo, Koichiro Shiba

“…ConclusionsThis study provides valuable insights into the impact of digital gaming on the health and well-being of older adults in a real-world context. …”
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Virtual Reality Simulation for Undergraduate Nursing Students for Care of Patients With Infectious Diseases: Mixed Methods Study by Wen Chang, Chun-Chih Lin, Julia Crilly, Hui-Ling Lee, Li-Chin Chen, Chin-Yen Han

“…ConclusionsThe findings suggest that VRS teaching significantly enhanced undergraduate nursing students’ infection control knowledge, learning attention, and confidence. Qualitative insights reinforced the quantitative results, highlighting the holistic benefits of VRS teaching in nursing education, including improved learning outcomes. …”
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Ly6E on tumor cells impairs anti-tumor T-cell responses: a novel mechanism of tumor-induced immune exclusion by Lan Hailin, Chen Yiting, Wu Yue, Li Lijun, Zhang Renlu, Chen Yunhan, Zhu Yanyang, Zhang Qiuyu

“…Conclusion Our study illuminated that Ly6E-expressing tumor cells facilitated the accumulation of M2 macrophages in TME, which contributes to CD8+ T cell exclusion and provides new insights for improving efficacy of cancer immunotherapy.…”
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Detection of CRISPR‒Cas and type I R–M systems in Klebsiella pneumoniae of human and animal origins and their relationship to antibiotic resistance and virulence by Xue Li, Ling Wang, Jinghuan Lin, Yingjuan Gu, Zhihua Liu, Jing Hu

“…Moreover, this study provides insights into the distributions of the two systems in K. pneumoniae from different hosts, and there is no significant difference in the prevalence of the two systems among K. pneumoniae spp. …”
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Effects of amino acid value-added urea on rice growth and nitrogen utilization. by Lin Cheng, Zongya Wang, Shuangshuang Huang, Hongyan Wu, Ruichao Li

“…To investigate the impact of amino acid value-added urea on rice growth and nitrogen utilization, this study aimed to provide insights into enhancing the quality and efficiency of traditional nitrogen fertilizers using small molecule active substances. …”
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Assessing the development of health technology assessment in Iran: a policy analysis using Kingdon’s Multiple streams framework: a qualitative study by Meysam Behzadifar, Saeed Shahabi, Ahad Bakhtiari, Samad Azari, Seyed Jafar Ehsanzadeh, Mohammad Yarahmadi, Masoud Behzadifar

“…Participants, consisting of 12 males and 4 females with an average age of 41.56 years and an average work experience of 14.37 years, provided insights into the current state of HTA. The participants included individuals in key leadership roles within public and private institutions, such as the Ministry of Health and Medical Education, hospital managers, policymakers, and senior academics. …”
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Pattern of Refractive Error among Patients attending a Tertiary Care Hospital in Southern Assam, India: A Cross-sectional Study by Nilanjan Kaushik Thakur, Ruma Das Debsikdar, Srawani Sarkar, Surabhi Prasad, S Lakshmi, Devajit Deka

“…Conclusion: This study offers key insights into the magnitude and types of UREs in South Assam, India. …”
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Women's enrollment in community-based health insurance and its determinants in Sidama national regional state, Ethiopia, 2024: A multilevel analysis. by Kare Chawicha Debessa, Keneni Gutema Negeri, Mesay Hailu Dangisso

“…Utilizing qualitative methods will yield insights into women's perceptions of CBHI, facilitating more effective strategies. …”
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Network analysis combined with genome-wide association study helps identification of genes related to amino acid contents in soybean by Kyujung Van, Sungwoo Lee, M. A. Rouf Mian, Leah K. McHale

“…Using a combination of approaches provides insights into the genetic control and pleiotropy among AA contents, which can be applied to mechanistic understanding of variation in AA content as well as tailored nutrition in cultivars developed from soybean breeding programs.…”
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Barriers and Facilitators in Implementing a Telemonitoring Application for Patients With Chronic Kidney Disease and Health Professionals: Ancillary Implementation Study of the NeLL... by Marion Delvallée, Abdallah Guerraoui, Lucas Tchetgnia, Jean-Pierre Grangier, Nassira Amamra, Anne-Laure Camarroque, Julie Haesebaert, Agnès Caillette-Beaudoin

“…Our results provide insights that can inform the design of effective, theory-driven interventions aimed at improving telemonitoring adoption and usage.…”
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