Drug utilization study of antiparkinsonian medication in Romania during 25 years by Camelia Bucsa, Denisa Bruhs, Anamaria Apan, Elena Francu, Cristina Mogosan, Irina Iaru

“…Observing the trend in antiparkinsonian medication utilization over time is essential for providing insights into their real-world use and uptake in a large population.…”
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Designing a Stock Recommender System Using the Collaborative Filtering Algorithm for the Tehran Stock Exchange by Marziyeh Nourahmadi, Ali Rahimi, Hojjatollah Sadeqi

“…This method is founded on two key assumptions: first, market inefficiency, meaning the stock market does not completely and accurately reflect all available information; and second, the presence of hidden information in stock movements, indicating that these movements contain valuable insights that can influence the prices of other stocks in the market. …”
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Reducing health inequalities in disasters: A cross-sectional study of the viability of ‘vulnerability’ terminology and of priority lists in the UK by Poppy Ellis Logan, Gabriella Rundblad, Marian Brooke Rogers, Richard Amlôt, Gideon James Rubin

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Enrichment of electrotrophic microorganisms from contrasting shallow-sea hydrothermal environments in bioelectrochemical reactors by Antoine Carissimo, Victoria Comes, Alenica Heussner, Anne-Hélène Prime, Roy E. Price, Gaël Erauso, Pierre-Pol Liebgott, Sven Kerzenmacher, Guillaume Pillot

“…In reactors reproducing the Prony Bay hydrothermal conditions, known facultative methylotrophs, such as Sphingomonas and Methylobacterium, were dominant and appeared to consume formate (provided as carbon source) but no electrons from the cathode.ConclusionThese results provide new insights into the distribution and diversity of electrotrophs in shallow-sea hydrothermal vents and allow the identification of potential novel biocatalysts for Microbial Electrosynthesis whereby electricity and carbon dioxide are converted into value-added products.…”
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Unlocking the power of population health management to strengthen primary health care by José Cerezo-Cerezo, Esteban de Manuel-Keenoy, Daniel Alton, Marc Bruijnzeels, Arnoldas Jurgutis, Melitta Jakab

“…By using quantitative and qualitative data insights, PHM helps primary care providers identify population cohorts with similar needs or ‘at risk’ of a given negative outcome/s. …”
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Effect of Geographic Regions on the Flavor Quality and Non-Volatile Compounds of Chinese Matcha by Hongchun Cui, Yun Zhao, Hongli Li, Min Ye, Jizhong Yu, Jianyong Zhang

“…This study provides new insights into the differences in metabolite profiles among typical Chinese matcha geographic regions with the same tea variety.…”
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Bio-active composition, antibacterial activity and molecular docking studies of Salicia nitida (Benth.) root extracts by Wisdom U. Ike, Okereke C. Stanley, Nosiri Ijeoma, Okamgba C. Okezie, Nwokocha W. Osita, Aguwanba Chinedu, Aaron C. Friday

“…Molecular docking simulations revealed valuable insights into the potential interactions between Class A beta-lactamase enzyme (PDB: 3BLM) with Butylated hydroxytoluene (CID: 31404) and 5-Eicosene (CID: 5364600). …”
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Impact of Radiation Therapy Techniques on Hippocampal Doses and Psychological Status in Patients With Nasopharyngeal Carcinoma by Gai X, Huang S, Zeng J, Chen J, Liu F, Li S, Lv W, Guo F, Cai C, Hong J, Su L

“…This perspective offers new insights for optimizing treatment strategies and improving quality of life.Keywords: nasopharyngeal carcinoma, IMRT, VMAT, hippocampal doses, psychological status…”
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Evaluation of In Vitro Production Capabilities of Indole Derivatives by Lactic Acid Bacteria by Bingyang Ma, Yan Zhao, Liping Liu, Jianguo Xu, Qingping Hu, Saisai Feng, Liangliang Zhang

“…The current study provides insights into the species- or genus-dependent capabilities for metabolizing indole derivatives. …”
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Preharvest Factors Affecting Quality on “Abate Fetel” Pears: Study of Superficial Scald with Multivariate Statistical Approach by Alessandro Bonora, Enrico Muzzi, Cristiano Franceschini, Alexandra Boini, Gianmarco Bortolotti, Kushtrim Bresilla, Giulio Demetrio Perulli, Melissa Venturi, Luigi Manfrini, Luca Corelli Grappadelli

“…Although superficial scald (SS) is well characterized on apples, there are only a few insights concerning the influence that agronomic and management variability may have on the occurrence of this physiological disorder on pears. …”
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Mutational Landscape of Bone Marrow CD19 and CD138 Cells in Waldenström Macroglobulinemia (WM) and IgM Monoclonal Gammopathy of Undetermined Significance (IgM MGUS) by Alessandra Trojani, Alessandro Beghini, Luca Emanuele Bossi, Marta Rachele Stefanucci, Cassandra Palumbo, Antonino Greco, Annamaria Frustaci, Barbara Di Camillo, Roberto Cairoli

“…Conclusion In conclusion, we uncovered new insights into the mutational landscape of WM, depicting a more complex involvement of the NF‐kB pathway, and providing evidence of the recurrence of some variants (MYD88, IL17RB, NFKB2, ATM, CARD11, PTPN13, and WNK2) also in IgM MGUS.…”
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Primary Clear Cell Adenocarcinoma of the Cervix: A Clinical Analysis of 18 Cases without Exposure to Diethylstilbestrol by Dongying Wang, Chunhua Zhao, Li Fu, Yang Liu, Weiyang Zhang, Tianmin Xu

“…In the future, larger samples of clinical data are required to confirm these insights.…”
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Neuroinflammation mediates the progression of neonate hypoxia-ischemia brain damage to Alzheimer’s disease: a bioinformatics and experimental study by Shengjie Zhang, Ruqiu Zhang, Zhaoqin Chen, Zihan Shao, An Li, Fan Li, Fang Huang

“…Gene-inflammation association analysis shows that the hub gene AREL1 is related to inflammatory response, while the protein-inflammation association analysis shows that the hub proteins AKT1 and MAPK14 are related to inflammatory response.ConclusionThis study provides new insights into the shared molecular mechanisms between AD and nHIBD. …”
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The dual anti-inflammatory and anticoagulant effects of Jianpi Huashi Tongluo prescription on Rheumatoid Arthritis through inhibiting the activation of the PI3K/AKT signaling pathw... by Fanfan Wang, Fanfan Wang, Jian Liu

“…In vitro co-culture model showed that XFC inhibited RA-related inflammatory responses and hypercoagulable states by suppressing the activation of the PI3K/AKT signaling pathway.ConclusionThis study demonstrates that XFC exerts its dual anti-inflammatory and anticoagulant effects, at least in part, by inhibiting the activation of the PI3K/AKT signaling pathway, providing potential insights into targeted therapy for RA.…”
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Association Between Diurnal Temperature Range and Risk of Cardiomyopathy-Induced Hospitalisation in Henan, China: A Time-Series Study by Zhang Z, Wang Y, Zhou Y, Pei J, Zhao G, Dong P, Yang K, Liu H, Xie N, Li X, Zang X, Lin F, Chen Z

“…AF and AN of low DTR on CM admissions were 51% and 2,936, respectively.Conclusion: Our results revealed a significant association between DTR and CM hospitalisations, providing valuable insights for the development targeted prevention and control measures.Keywords: cardiomyopathy, diurnal temperature range, distributed lag non-linear model, time-series…”
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Research on the impact of land use and land cover changes on local meteorological conditions and surface ozone in the north China plain from 2001 to 2020 by Chunsheng Fang, Xinlong Li, Juan Li, Jiaqi Tian, Ju Wang

“…It optimizes the model’s simulation of regional air quality and provides new insights into understanding the effects of urbanization on meteorological conditions and air quality.…”
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Preparation, Modification, Characterization and Antioxidant Activities of Apigenin Liposomes by Siyu DAI, Ying TANG, Nian LIU, Lu HE, Miao GU, Chenbo FENG, Jin REN, Zhengjie FANG

“…Conclusion: The CS-AP-L prepared in this study exhibits appropriate particle size, uniform distribution, high encapsulation efficiency, good stability, and the capability to enhance the antioxidant activities of apigenin, thereby offering valuable insights for the development of apigenin derivative products.…”
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Rumen DNA virome and its relationship with feed efficiency in dairy cows by Xiaohan Liu, Yifan Tang, Hongyi Chen, Jian-Xin Liu, Hui-Zeng Sun

“…The integration of these data offers novel insights into the mechanisms by which rumen viruses may regulate nutrient utilization, potentially influencing FE in dairy cows. …”
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Novel Nanozyme-Based Multicomponent in situ Hydrogels with Antibacterial, Hypoxia-Relieving and Proliferative Properties for Promoting Gastrostomy Tube Tract Maturation by Xiao F, Yan B, Yuan T, He Y, Zhang X, He X, Peng W, Xu Y, Cao J

“…The hydrogel group exhibited a significant promotion in collagen content and reduction in HIF-1α, which effectively hastened tract maturation.Conclusion: Therefore, our study provides new and critical insights into a strategy to design bioactive hydrogels with multiple functions, which can open up a new avenue for accelerated wound healing after gastrostomy. …”
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Socio-demographic and clinical determinants of self-care in adults with type 2 diabetes: a multicenter cross-sectional study in Zhejiang province, China by Xuefen Lan, Xiaozhen Ji, Xiaojia Zheng, Xiaoyu Ding, Hongyi Mou, Shunfei Lu, Bin Ye

“…Conclusions/interpretation The findings of this study provide invaluable insights into the factors affecting self-care among Chinese adults with type 2 diabetes. …”
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