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14981
Human intestinal nematode infections in Sri Lanka: A scoping review.
Published 2024-12-01“…Sri Lanka's experiences and control measures offer valuable insights for low-income countries in South Asia and beyond, particularly in managing HINIs with limited resources.…”
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14982
Identification of EGR1 as a Key Diagnostic Biomarker in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Through Machine Learning and Immune Analysis
Published 2025-02-01“…Furthermore, additional cellular experiments and animal model validations confirmed that the expression trends of EGR1 are highly consistent with our analytical findings.Conclusion: Our research has confirmed EGR1 as a key gene in MASLD, providing novel insights into the disease’s pathogenesis and identifying new therapeutic targets for its treatment.Keywords: metabolic dysfunction-associated steatotic liver disease, immune infiltration, machine learning, TF-miRNA-mRNA network, EGR1…”
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14983
Stratified Assessment of Urban Low-Carbon Travel Potential
Published 2025-02-01“…A relationship curve is fitted, which intriguingly exhibits a reverse “S” shape, allowing for the identification of the “rapid release zone” and “key points” on the curve. These insights are essential for effectively targeting interventions to increase the adoption of low-carbon travel modes. …”
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14984
A systematic review and meta-analysis of randomized controlled trials for physical activity among colorectal cancer survivors: directions for future research
Published 2025-01-01“…This study offers preliminary insights into the appropriate patterns of PA interventions (e.g., frequency, intensity, type) for enhancing total PA levels in CRC survivors. …”
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14985
Digital Age Transformation in Patient-Physician Communication: 25-Year Narrative Review (1999-2023)
Published 2025-01-01“…Additionally, exploring how emerging technologies, such as artificial intelligence, can support these goals may provide valuable insights for enhancing health communication.…”
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14986
Dataset on electricity usage measurement for lower-to-middle-income primary and secondary schools in Western Cape, South AfricaMendeley Data
Published 2025-04-01“…The dataset holds significant value for stakeholders in the educational and energy sectors, providing detailed insights into energy usage trends that are crucial for strategic planning, policy development, and operational adjustments in similar socioeconomic environments.…”
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14987
Multi-decadal stability of water ages and tracer transport in a temperate-humid river basin
Published 2025-01-01“…The temporal dynamics of water ages provide crucial insights into hydrological processes and transport mechanisms, yet there remains a significant gap in quantifying water age variability across different temporal scales. …”
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14988
Genetic context modulates aging and degeneration in the murine retina
Published 2025-01-01“…The retina and brain share many biological properties; thus, insights into retinal aging and degeneration may shed light onto similar processes in the brain. …”
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14989
Direct and indirect effects of land use on microbiomes of trap-nesting solitary bee larvae and nests
Published 2025-01-01“…However, the pupae microbiome remained unaffected, indicating a reorganization of the microbiome during metamorphosis, which is not significantly influenced by land use and available resources.DiscussionOur findings provide new insights into the factors shaping environmental transmission and changes in solitary bee microbiomes. …”
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14990
Mapping knowledge landscapes and emerging trends in artificial intelligence for antimicrobial resistance: bibliometric and visualization analysis
Published 2025-01-01“…ObjectiveTo systematically map the knowledge landscape and development trends in artificial intelligence (AI) applications for antimicrobial resistance (AMR) research through bibliometric analysis, providing evidence-based insights to guide future research directions and inform strategic decision-making in this dynamic field.MethodsA comprehensive bibliometric analysis was performed using the Web of Science Core Collection database for publications from 2014 to 2024. …”
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14991
Understanding Human Papillomavirus Vaccination Hesitancy in Japan Using Social Media: Content Analysis
Published 2025-02-01“…Future public health strategies can benefit from these insights by designing effective interventions to boost vaccine confidence and uptake.…”
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14992
Analysis of DNA cox1 barcoding revealed novel haplotype in Schistosoma haematobium isolated from Western Sudan
Published 2025-01-01“…In conclusion, this study identified a novel S. haematobium strain and provides insights into the evolutionary history and phylogeography of S. haematobium in Sudan, particularly in the western region. …”
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14993
Phosphorylation of Bok at Ser-8 blocks its ability to suppress IP3R-mediated calcium mobilization
Published 2025-01-01“…This study provides new insights on the role of Bok, its interaction with IP3Rs, and the impact it has on IP3R-mediated Ca2+ mobilization.…”
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14994
Lightweight Detection and Counting of Maize Tassels in UAV RGB Images
Published 2024-12-01“…This study enhances the model’s adaptability to sunlight, enabling high performance under suboptimal conditions and offering insights for real-time intelligent agriculture monitoring with UAV technology.…”
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14995
Neurodevelopmental Disorders and Connective Tissue-Related Symptoms: An Exploratory Case-Control Study in Children
Published 2024-12-01“…The familial prevalence of these symptoms suggests a potential genetic underpinning, further supporting the hypothesis of shared aetiological pathways. These insights underscore the need for interdisciplinary research to explore the mechanisms linking neurodevelopmental and connective tissue disorders, aiming to improve diagnosis and management strategies.…”
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14996
Mendelian Randomization Reveals Potential Causal Relationships Between DNA Damage Repair-Related Genes and Inflammatory Bowel Disease
Published 2025-01-01“…We found that DNA methylation of <i>Erbb2</i> and <i>Gpx1</i> significantly impacted their gene expression levels offering insights into the potential regulatory mechanisms of risk variants on IBD. …”
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14997
Untangling the complex mechanisms associated with Alzheimer's disease in elderly patients using high-throughput RNA sequencing data and next-generation knowledge discovery methods:...
Published 2025-01-01“…These findings highlight the complex molecular mechanisms underlying AD and provide insights into potential therapeutic strategies. Further research is needed to validate these findings and to develop personalized treatment approaches for AD in elderly patients.…”
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14998
Clinical characteristics and prognosis of children with culture-negative osteoarticular infections: a meta-analysis based on cohort studies
Published 2025-01-01“…This study aims to investigate the clinical characteristics and prognosis of culture-negative OAIs compared to culture-positive OAIs through a meta-analysis, providing insights to optimize treatment strategies. Methods: A systematic search was conducted to identify cohort studies comparing the clinical characteristics and prognosis of children with culture-negative OAIs to those with culture-positive OAIs. …”
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14999
Large Language Model Approach for Zero-Shot Information Extraction and Clustering of Japanese Radiology Reports: Algorithm Development and Validation
Published 2025-01-01“…Clustering allows for the identification of similar lesions and disease patterns across a broad dataset, making it useful for aggregating information and discovering new insights in medical imaging. However, most publicly available medical datasets are in English, with limited resources in other languages. …”
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15000
Single-cell RNA sequencing reveals the dysfunctional characteristics of PBMCs in patients with type 2 diabetes mellitus
Published 2025-01-01“…Exploring T2DM biomarkers via single-cell RNA sequencing (scRNA-seq) could provide new insights into the underlying molecular mechanisms.MethodsThe clinical trial registration number is ChiCTR2100049613. …”
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