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  1. 14801

    Measurement-Based Prediction of mmWave Channel Parameters Using Deep Learning and Point Cloud by Hang Mi, Bo Ai, Ruisi He, Anuraag Bodi, Raied Caromi, Jian Wang, Jelena Senic, Camillo Gentile, Yang Miao

    Published 2024-01-01
    “…Third, we evaluate the proposed prediction model and training method, by comparing prediction results with measured ground truth. To provide insights on what training inputs are best, we demonstrate the impacts of different combinations of input information on prediction accuracy. …”
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  2. 14802

    Non-pharmacological interventions for primary hypertension: a systematic review and network meta-analysis protocol by Tao Xu, Fan-rong Liang, Qifu Li, Taipin Guo, Ziwen Chen, Yun-Jie Shu, Xueli Zhou

    Published 2025-01-01
    “…This study aims to use network meta-analysis (NMA) to synthesise existing evidence on non-pharmacological interventions for PH, offering updated clinical insights and evidence-based support to optimise treatment strategies. …”
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  3. 14803
  4. 14804
  5. 14805

    Development of monoclonal antibodies against P. gingivalis Mfa1 and their protective capacity in an experimental periodontitis model by Mingya Cao, Siyu Wang, Shengke Zhou, Min Yan, Yu Zou, Yuan Cui, Xinyu Lou, Yichang Gao, Ying Chen, Zijing Han, Yi Qian, Jingying Chen, Xia Li

    Published 2025-01-01
    “…These results show that anti-Mfa1 mAbs can be beneficial in alleviating P. gingivalis infections, and provide important insights for the development of adequate adjuvant treatment regimens for Mfa1-targeted therapeutics.IMPORTANCEFimbriae (pili) play an important role in bacterial adhesion, invasion of host cells and tissues, and formation of biofilms. …”
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  6. 14806

    Soil variation response is mediated by growth trajectories rather than functional traits in a widespread pioneer Neotropical tree by Levionnois, Sébastien, Tysklind, Niklas, Nicolini, Eric, Ferry, Bruno, Troispoux, Valérie, Le Moguedec, Gilles, Morel, Hélène, Stahl, Clément, Coste, Sabrina, Caron, Henri, Heuret, Patrick

    Published 2023-05-01
    “…The intraspecific variability is higher for growth trajectories than functional traits for  C. obtusa, revealing the complementarity of the architectural approach with the functional approach to gain insights on the way trees manage their resources over their lifetime. …”
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  7. 14807

    Deciphering the role of metal ion transport-related genes in T2D pathogenesis and immune cell infiltration via scRNA-seq and machine learning by Zuhui Pu, Zuhui Pu, Tony Bowei Wang, Ying Lu, Ying Lu, Zijing Wu, Zijing Wu, Yuxian Chen, Ziqi Luo, Xinyu Wang, Lisha Mou, Lisha Mou

    Published 2025-01-01
    “…The identified pathways and genes provide valuable insights into the disease mechanisms and potential targets for intervention.…”
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  8. 14808

    Magnitude and dynamics of the T-cell response to SARS-CoV-2 infection at both individual and population levels by Thomas M. Snyder, Rachel M. Gittelman, Mark Klinger, Damon H. May, Edward J. Osborne, Ruth Taniguchi, H. Jabran Zahid, Ian M. Kaplan, Jennifer N. Dines, Matthew T. Noakes, Ravi Pandya, Xiaoyu Chen, Summer Elasady, Emily Svejnoha, Peter Ebert, Mitchell W. Pesesky, Patricia De Almeida, Hope O’Donnell, Quinn DeGottardi, Gladys Keitany, Jennifer Lu, Allen Vong, Rebecca Elyanow, Paul Fields, Hussein Al-Asadi, Julia Greissl, Lance Baldo, Simona Semprini, Claudio Cerchione, Fabio Nicolini, Massimiliano Mazza, Ottavia M. Delmonte, Kerry Dobbs, Rocio Laguna-Goya, Gonzalo Carreño-Tarragona, Santiago Barrio, Luisa Imberti, Alessandra Sottini, Eugenia Quiros-Roldan, Camillo Rossi, Andrea Biondi, Laura Rachele Bettini, Mariella D’Angio, Paolo Bonfanti, Miranda F. Tompkins, Camille Alba, Clifton Dalgard, Vittorio Sambri, Giovanni Martinelli, Jason D. Goldman, Jason D. Goldman, James R. Heath, Helen C. Su, Luigi D. Notarangelo, Estela Paz-Artal, Joaquin Martinez-Lopez, Bryan Howie, Jonathan M. Carlson, Harlan S. Robins

    Published 2025-01-01
    “…As an application of these data, we trained a classifier to diagnose SARS-CoV-2 infection based solely on TCR sequencing from blood samples, and observed, at 99.8% specificity, high early sensitivity soon after diagnosis (Day 3–7 = 85.1% [95% CI = 79.9–89.7]; Day 8–14 = 94.8% [90.7–98.4]) as well as lasting sensitivity after recovery (Day 29+/convalescent = 95.4% [92.1–98.3]).DiscussionThe approaches described in this work provide detailed insights into the adaptive immune response to SARS-CoV-2 infection, and they have potential applications in clinical diagnostics, vaccine development, and monitoring.…”
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  9. 14809

    Optimizing Energy and Spectral Efficiency in Mobile Networks: A Comprehensive Energy Sustainability Framework for Network Operators by Luis Mata, Marco Sousa, Pedro Vieira, Maria Paula Queluz, Antonio Rodrigues

    Published 2025-01-01
    “…These findings provide practical insights for developing more sustainable network operations.…”
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  10. 14810

    Limited restoration of T cell subset distribution and immune function in older people living with HIV-1 receiving HAART by Na Li, Hong-Yi Zheng, Wei Li, Xiao-Yan He, Mi Zhang, Xia Li, Ren-Rong Tian, Xing-Qi Dong, Zhi-Qiang Shen, Yong-Tang Zheng

    Published 2025-01-01
    “…The objective of this study was to investigate the impact of aging and HAART on T cell subsets and function in PLWH across different age groups, thereby providing novel insights into the prognosis of older PLWH. Method This study was conducted at Yunnan AIDS Care Center, China, to explore the immunological responses of old PLWH to HAART and compared with the middle-age and the younger. …”
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  11. 14811

    Heat shock transcription factor 1 facilitates liver cancer progression by driving super‐enhancer‐mediated transcription of MYCN by Yizhe Liu, Qili Shi, Yue Su, Zhiao Chen, Xianghuo He

    Published 2024-09-01
    “…Further exploration of this axis could yield valuable insights into novel treatment strategies for HCC.…”
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  12. 14812

    Characterisation of HBV and co-infection with HDV and HIV through spatial transcriptomics by Upkar S Gill, Patrick T F Kennedy, Andrew Hall, Rageshri Dhairyawan, Alberto Quaglia, James M Harris, Colin Nixon, Fadi Issa, Amy Cross, Edward Arbe-Barnes, Jane A McKeating, Dimitra Peppa

    Published 2024-10-01
    “…Spatial transcriptomics can provide new insights into the complex intrahepatic biological processes, guiding new personalised treatments. …”
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  13. 14813

    Identification and validation of immune and diagnostic biomarkers for interstitial cystitis/painful bladder syndrome by integrating bioinformatics and machine-learning by Tao Zhou, Can Zhu, Wei Zhang, Qiongfang Wu, Mingqiang Deng, Zhiwei Jiang, Longfei Peng, Hao Geng, Zhouting Tuo, Zhouting Tuo, Ci Zou

    Published 2025-01-01
    “…Among them, PLAC8 is a promising diagnostic biomarker that modulates the immune response in patients with IC/BPS, which provides new insights into the future diagnosis of IC/BPS.…”
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  14. 14814

    Do you think medicines can be prescribed in a more eco-directed, greener way? A qualitative study based on public and prescriber focus groups on the impact of pharmaceuticals in Sc... by Claire Anderson, Lydia Niemi, Naoko Arakawa, Mark Taggart, Stuart Gibb, Sharon Pfleger

    Published 2025-01-01
    “…Although the public representatives were generally open to the concept of EDSP, this decision required weighing pros/cons considering personal health choices, information accessibility and transparency, and trust in and time with prescribers.Conclusions This study identified new insights from prescribers and the public related to the concept of, and barriers to, EDSP in Scotland, as well as perspectives regarding knowledge support tools and information communication. …”
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  15. 14815

    Symptom Network and Subgroup Analysis in Patients with Exacerbation of Chronic Obstructive Pulmonary Disease: A Cross-Sectional Study by Yu C, Xu M, Pang X, Zhang Y, Cao X, Xu Y, Huang S, Zhao H, Chen C

    Published 2025-01-01
    “…This study identifies core symptoms, bridge symptoms, and symptom subgroups, offering valuable insights for precision symptom management in ECOPD.Keywords: chronic obstructive pulmonary disease, COPD, exacerbation, precision care, network analysis, latent class analysis…”
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  16. 14816

    A Case Study on Multi-Real-Option-Integrated STO-PF Models for Strengthening Capital Structures in Real Estate Development by Jung Kyu Park, Jun Bok Lee, Young Mee Ahn, Ga Young Yoo

    Published 2025-01-01
    “…It contributes to the theoretical understanding of STO-based financing and provides practical insights for developers seeking flexible and innovative financing solutions in the real estate sector. …”
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  17. 14817

    c-FLIP and microRNA 708-5p gene expression in newly diagnosed and chemotherapy in acute myeloid leukemia of Iraqi patient by Jaafar Sadiq Jaafar, Hiba Muneer Abdual Hassan Al-Kafagi, Israa Hussein Hamzah

    Published 2024-12-01
    “…Furthermore, miRNA 708-5p can act as a prognostic indicator in AML, with its expression levels offering valuable insights into disease progression and patient response to treatment. …”
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  18. 14818

    Assessment of Impact of Meteorology and Precursor in Long-term Trends of PM and Ozone in a Tropical City by Christian Mark G. Salvador, Angeles D. Alindajao, Karen B. Burdeos, Mark Anthony M. Lavapiez, Jhon Robin Yee, Angel T. Bautista, Preciosa Corazon B. Pabroa, Rey Y. Capangpangan

    Published 2021-12-01
    “…Overall, our results provide insights to better comprehend the sources of the variability of O3 and PM on a long-term temporal scale, as well as implications on relevant environmental policies in controlling air pollutants in a tropical developing region.…”
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  19. 14819

    Structure-based identification of HNF4α agonists: Rosmarinic acid as a promising candidate for NAFLD treatment by Xi Chen, Xinqi Zhu, Gang Wu, Xiaobo Wang, Yu Zhang, Nan Jiang

    Published 2025-01-01
    “…Additionally, electrostatic interactions between the aromatic moieties of the compounds and HNF4α residues were found to play a crucial role in ligand binding. Leveraging these insights, we performed a high-throughput virtual screening of 2131 natural compounds, using the binding modes of NCT and NFT as reference templates. …”
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  20. 14820

    Causal Association Between Obstructive Sleep Apnea and Migraine: A Bidirectional Mendelian Randomization Study by Wang YP, Wei HX, Hu YY, Zhang C, Niu YM

    Published 2025-01-01
    “…In addition, increased risk of migraine and migraine without aura on OSA occurrence were identified in the reverse analysis, but these results were subsequently negated with MVMR analysis.Conclusion: According to the current findings, there was a preliminary causal effect of OSA on MA among European descendants.Clinical Relevance: These findings suggest a potential causal effect of OSA on migraine and provide new insights to prevent and manage the two disorders.Keywords: obstructive sleep apnea, migraine, Mendelian randomization, causal effect…”
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