In Vitro Mechanism of Action of Acanthospermum hispidum in Trypanosoma brucei by Aboagye Kwarteng Dofuor, Temitayo Samson Ademolue, Karen Nana Akua Kuampah, Frederick Ayertey, Theresa Manful Gwira

“…The results provide useful pharmacological insights into the chemotherapeutic potential of A. hispidum toward drug discovery for African trypanosomiasis.…”
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The Impact of nanoparticles (B4C-Al2O3) on mechanical, wear, fracture behavior and machining properties of formwork grade Al7075 composites by T. B. Prakash, M. Gangadharappa, Santhosh Somashekar, M. Ravikumar

“…These findings offer valuable insights into the ease of machining of composite metal alloys, emphasizing the importance of parameter selection and optimization for desired machining outcomes. …”
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Numerical simulation of an HTL-free carbon-based perovskite solar cell with graphitic carbon nitride doped zinc oxide as electron transport layers by Joseph Kariuki, Nicholas Rono, Chinedu Christian Ahia, Eric Kibagendi Osoro, Edson L. Meyer

“…Nonetheless, the proposed ETL materials were chosen by mimicking the actual experimental investigation with an aim of giving more insights theoretically. These results will help in further advancement and fabrication of the high performance HTL-free perovskite solar cells (PSCs) for anticipated commercialization.…”
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Adolescent HIV prevent and care framework: A global scoping review protocol- BSGH 006. by Gamji Rabiu Abu-Ba'are, Osman Wumpini Shamrock, Darcey Rodriguez, George Rudolph Kofi Agbemedu, LaRon E Nelson

“…We expect this review to yield critical insights into the present landscape of HIV prevention and care for individuals aged 10-19. …”
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Digital leadership in quantity surveying: unveiling key characteristics and their role in driving digital transformation by Darren Vermaak, Gerrit Crafford

“…Practically, the study provides valuable insights for quantity surveying firms. It emphasises the importance of developing digital leadership capabilities centred on the identified traits. …”
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Genome-wide association studies identify two novel BMP15 mutations responsible for an atypical hyperprolificacy phenotype in sheep. by Julie Demars, Stéphane Fabre, Julien Sarry, Raffaella Rossetti, Hélène Gilbert, Luca Persani, Gwenola Tosser-Klopp, Philippe Mulsant, Zuzanna Nowak, Wioleta Drobik, Elzbieta Martyniuk, Loys Bodin

“…Our results bring new insights into the key role played by the BMP15 protein in ovarian function and could contribute to a better understanding of the pathogenesis of women's fertility disorders.…”
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PENGARUH INVESTMENT OPPORTUNITY SET DAN KEPEMILIKAN MANAJERIAL TERHADAP NILAI PERUSAHAAN YANG DIMEDIASI OLEH KEBIJAKAN DIVIDEN by Luthfy Maghfiroh Ilahi, Ni Putu Santi Suryantini

“…The study underscores the importance of aligning investment opportunities, managerial ownership, and dividend policies to enhance firm value. These insights are expected to guide managers in making informed decisions on leveraging dividend policies and investment strategies for sustainable growth.…”
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Glucometabolic-Related Genes as Diagnostic Biomarkers and Therapeutic Targets for Alzheimer’s Disease and Type 2 Diabetes Mellitus: A Bioinformatics Analysis by Shuo Liu, He Chen, Xiao-Dong He, Xiao-Ou Yang

“…This study appears to be the first to extensively investigate glucometabolic-associated DEGs and key genes in both AD and T2DM, utilizing multiple datasets. These insights are set to enhance our understanding of the complex pathophysiology underlying these widespread chronic diseases.…”
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Relationship between social support and depressive symptoms among internal migrant workers and the mediating role of healthy lifestyle: a cross-sectional study in China by Yunyun Wang, Beizhu Ye, Clifford Silver Tarimo, Yiyang Chen, Mingze Ma, Jingru Liu, Shuo Han, Kunyu Xue, Binghe Zuo, Yalin Song

“…Mediation analysis revealed that a healthy lifestyle partially mediated the relationship between social support and depressive symptoms among internal migrant workers, with a mediation effect of −0.063, accounting for 18.75% of the total effect.Conclusion This study provides insights into the complex interplay between social support, healthy lifestyle and depressive symptoms among internal migrant workers in China. …”
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GPX3 as a Novel and Potential Therapeutic Target in the Shared Molecular Mechanisms of Traumatic Brain Injury and Parkinson’s Disease by Wang Y, Fang J, Yuan Q, Yu J, Hu J

“…The glutathione peroxidase 3 (GPX3) gene emerged as a pivotal hub gene, with its expression significantly altered in both TBI and PD datasets.Conclusion: This study underscores the critical role of GPX3 in the molecular intersection of TBI and PD, suggesting it as a novel and potential therapeutic target, offering new insights into potential therapeutic strategies.Keywords: traumatic brain injury, Parkinson’s disease, bioinformatics, oxidative stress, mitochondrial dysfunction, neurodegenerative diseases…”
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Metatranscriptomes-based sequence similarity networks uncover genetic signatures within parasitic freshwater microbial eukaryotes by Arthur Monjot, Jérémy Rousseau, Lucie Bittner, Cécile Lepère

“…All these protein families could offer valuable insights for developing antiparasitic treatments in health and economic contexts. …”
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Case report: Long-term GPS tracking throughout the breeding and non-breeding seasons of the streaked shearwater Calonectris leucomelas by Taito Kamata, Masaki Shirai, Kazuhiko Hirata, Takahiro Sato, Haruka Mukai, Maki Yamamoto, Tsuneo Sekijima

“…The GPS tracking data obtained in this study, while not a statistically sufficient sample size, are valuable and provide new insights into the environmental preferences of SS during early breeding and non-breeding seasons; life stages for which little information is available.…”
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Factors influencing osteoradionecrosis progression during hyperbaric oxygen therapy: A case study [version 2; peer review: 1 approved, 2 approved with reservations] by Khadija Bahrini, Chaima Zitouni, Sameh Mezri, Hedi Gharsallah, Wiem Boughzala, Mounir Haggui

“…Conclusion Our study provides valuable insights into the management of ORN by identifying key predictors that influence the post-therapeutic evolution of head and neck ORN after HBOT.…”
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Community Caregivers’ Perspectives on Health IT Use for Children With Medical Complexity: Qualitative Interview Study by Farah Elkourdi, Onur Asan

“…By including their perspective on HIT development, we can better appreciate the challenges they face, the insights they offer, and the ways in which they bridge gaps in care, support, and resources. …”
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Detection of Invasive Species (Siam Weed) Using Drone-Based Imaging and YOLO Deep Learning Model by Deepak Gautam, Zulfadli Mawardi, Louis Elliott, David Loewensteiner, Timothy Whiteside, Simon Brooks

“…Future research will focus on developing tools to merge duplicates, gather georeference data, and report detections from large image datasets more efficiently, providing valuable insights for practical applications in environmental management at the catchment scale.…”
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Implementing Namaste Care in nursing care homes for people with advanced dementia: a systematically constructed review with framework synthesis by Serena Salvi, Nancy Preston, Nicola Cornally, Catherine Walshe, on behalf of the In-Touch Consortium

“…A framework synthesis of the results was conducted, which involves systematically combining qualitative and quantitative data within a structured analytical framework to identify overarching themes and insights. Findings Twenty-five studies met the inclusion criteria. …”
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Exploration of flame characteristics of gasoline engine fuelled by gasoline-pentanol blends using combustion endoscopy by S. Kumaravel, C. G. Saravanan, M. Vikneswaran, Vallinayagam Raman, J. Sasikala, Femilda Josephin J.S., Sulaiman Ali Alharb, Arivalagan Pugazhendhi, Edwin Geo Varuvel, Haiter Lenin Allasi

“…The flame intensity and distribution area increased with the addition of pentanol in gasoline, demonstrating improved in-cylinder combustion with increased peak in-cylinder pressure and heat release rate. The insights on the flame characteristics of pentanol–gasoline blends were used to rationalize the discussion on engine performance and emissions. …”
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Evaluating the Impact of Data Transformation Techniques on the Performance and Interpretability of Software Defect Prediction Models by Yu Zhao, Zhiqiu Huang, Lina Gong, Yi Zhu, Qiao Yu, Yuxiang Gao

“…Based on our findings, we recommend that (1) considering the impact of data transformation methods on model performance and interpretability when designing SDP approaches as transformations can improve model accuracy, and potentially obscure important features, which lead to challenges in interpretation, (2) conducting comparative experiments with and without the transformations to validate the effectiveness of proposed methods which are designed to improve the prediction performance, and (3) tracking changes in the most important features before and after applying data transformation methods to ensure precise and traceable interpretability conclusions to gain insights. Our study reminds researchers and practitioners of the need for comprehensive considerations even when using other similar simple data processing methods.…”
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Exploring the immunohistochemical profile of basosquamous carcinoma and its clinicopathological associations by Cemile Tuğba Altunel, Gonca Özgün, Arzu Karataş, Özlem Özen, Deniz Seçkin, Tülin Güleç, Deren Özcan

“…Immunohistochemical studies offer insights into the tumor's genetic background. However, extensive investigations into its immunophenotype are lacking, and existing data present conflicting results. …”
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Machine Selection for Inventory Tracking with a Continuous Intuitionistic Fuzzy Approach by Ufuk Cebeci, Ugur Simsir, Onur Dogan

“…The framework contributes to lean manufacturing by providing actionable insights and robust sensitivity analyses, ensuring decision-making reliability under fluctuating conditions. …”
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