Brain penetration of peripheral extracellular vesicles from Alzheimer's patients and induction of microglia activation by Hermine Counil, Rummenigge Oliveira Silva, Jean‐Michel Rabanel, Charlotte Zaouter, Mohamed Haddad, Mohamed Raâfet Ben Khedher, Davide Brambilla, Tamas Fülöp, Shunmoogum A. Patten, Charles Ramassamy

“…These findings contribute to novel insights into the fate of pEVs following their passage through the BBB in vitro and in vivo, and demonstrate for the first time that pEVs from AD patients affect microglia activity. …”
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Impact of #PCOSweightloss: A global X hashtag analysis study of weight loss narratives in the PCOS community by Munaza Afaq, Kumar Vashisht, Areen Al-Dhoon, Divya Abraham, Atanas G. Atanasov, Maima Matin, Zara Arshad, Rahul Kashyap, Faisal A. Nawaz

“…Objective This study aims to analyze the trends of #PCOSweightloss on X to gain insights into the social media metrics, including overall hashtag reach, key themes, and potential influence on management practices of PCOS. …”
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Interventions to improve media coverage of medical research: a codesigned feasibility and acceptability study with Australian journalists by Brooke Nickel, Ray Moynihan, Alexandra Barratt, Kirsten J McCaffery, Loai Albarqouni, Tessa Copp, Thomas Dakin, Liam Mannix

“…Analysis of free-text responses identified several areas for improvement, such as including more examples to aid understanding of the counterintuitive topic of overdiagnosis and more time for discussion.Conclusions Piloting suggested the multicomponent training intervention is acceptable to journalists and provided important feedback and insights to inform a future trial of the intervention’s impact on media coverage of medicine.…”
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In vitro and in vivo investigations of selected varieties of Areca catechu L - Phytochemical analysis, antiulcer, and wound healing activity by R. Deveswaran, D.J. Madhu Kumar, V. Madhavan, Soma Chaki, Misbah Khan, Govind R. Kadambi, B.V. Basavaraj, J. Anbu

“…Overall, this research provides valuable insights into the phytochemical composition and medicinal properties of arecanuts from different regions of Karnataka. …”
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miR‐130a‐3p regulated TGF‐β1‐induced epithelial‐mesenchymal transition depends on SMAD4 in EC‐1 cells by Xiaokang Tian, Qian Fei, Mingyu Du, Hongming Zhu, Jinjun Ye, Luxi Qian, Zhiwei Lu, Wenjun Zhang, Yan Wang, Fanyu Peng, Jie Chen, Baoling Liu, Qian Li, Xia He, Li Yin

“…In conclusion, this study provides new insights into the mechanism underlying ESCC metastasis. …”
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Sub-District Level Spatiotemporal Changes of Carbon Storage and Driving Factor Analysis: A Case Study in Beijing by Yirui Zhang, Shouhang Du, Linye Zhu, Tianzhuo Guo, Xuesong Zhao, Junting Guo

“…The findings from this study offer valuable insights for the sustainable advancement of ecological conservation and urban development in Beijing.…”
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Single‐cell landscape of the intrahepatic ecosystem in alcohol‐related liver disease by Xiaofang Zhao, Senyan Wang, Qi Liu, Wenjuan Wei, Xiaoyan Sun, Hao Song, Jing Xu, Shuijun Zhang, Hongyang Wang, Jing Fu

“…Our study provides important insights that Wnt signalling can be targeted in patients with advanced alcohol‐related cirrhosis to prevent malignant transformation. …”
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Analyzing Gait Dynamics and Recovery Trajectory in Lower Extremity Fractures Using Linear Mixed Models and Gait Analysis Variables by Mostafa Rezapour, Rachel B. Seymour, Suman Medda, Stephen H. Sims, Madhav A. Karunakar, Nahir Habet, Metin Nafi Gurcan

“…This model also adjusted for varying intervals between assessments. Our study provided insights into gait recovery across different fracture types using data from 318 patients who experienced no complications or readmissions during their recovery. …”
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RETRACTED ARTICLE: CKS2 induces autophagy-mediated glutathione metabolic reprogramming to facilitate ferroptosis resistance in colon cancer by Leilei Yang, Chengfeng Fang, Jiaju Han, Yufeng Ren, Zaiping Yang, Lingyan Shen, Dinghai Luo, Ruili Zhang, Yan Chen, Shenkang Zhou

“…These findings offer new insights into targeting CKS2 for CC treatment and shed light on the mechanism of ferroptosis in CC.…”
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Exploring the dynamics of seasonal surface features using coastal and regional ocean community model by D. Jaishree, P.T. Ravichandran, D.V. Thattai

“…Understanding the changes in circulation patterns provides valuable insights into the Bay dynamics. It helps identify the potential impacts of climate change, ocean currents, and other factors on the bay’s ecosystem. …”
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Left ventromedial prefrontal cortex inhibitory rTMS as an anti-stress intervention in opioid use disorder: Trial design by Tabitha E. Moses, Danielle Lenz, Leslie H. Lundahl, Nicholas A. Mischel, Christine Rabinak, Mark K. Greenwald

“…Conclusion: Our findings should offer insights into how neural networks modulate drug-seeking and associated dysfunctions in people with SUDs. …”
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The association of single nucleotide polymorphisms in tumor necrosis factor 3 with susceptibility/resistance of Magallana gigas to Halomonas sp. 7T by Hongmei Fan, Qingyu Peng, Tianbao Liu, Lei Fang, Chuanyan Yang, Ning Kong, Lingling Wang, Linsheng Song

“…These results provided insights into the molecular mechanism of different oyster populations responding to bacteria, which suggested that the increased bacterial resistance of bacterial-resistant population (compared with common population) was associated with the higher expression of MgTNF-3. …”
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Prediction of compressive strength and characteristics analysis of semi-flexible pavement desert sand grouting material based upon hybrid-BP neural network by Wenbang Zhu, Yuhang Li, Xiumei Zheng, Enze Hao, Dali Zhang, Zhen Wang

“…Therefore, GA - BPNN demonstrated the highest predictive accuracy for the compressive strength of DSGM, providing novel insights for the mix design of DSGM.…”
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Biomarker Investigation Using Multiple Brain Measures from MRI Through Explainable Artificial Intelligence in Alzheimer’s Disease Classification by Davide Coluzzi, Valentina Bordin, Massimo W. Rivolta, Igor Fortel, Liang Zhan, Alex Leow, Giuseppe Baselli

“…Then, differences in explainability patterns between the two models were assessed to explore the insights offered by each piece of data (i.e., MRI vs. connectivity). …”
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In-silico study of E169G and F242K double mutations in leucine-rich repeats (LRR) polygalacturonase inhibiting protein (PGIP) of Gossypium barbadense and associated defense mechani... by Sneha Murmu, Mayank Rashmi, Dipak T. Nagrale, Tejasman Kour, Mahender Kumar Singh, Anurag Chaurasia, Santosh Kumar Behera, Raja Shankar, Rajiv Ranjan, Girish Kumar Jha, Shailesh P. Gawande, Neelakanth S. Hiremani, Y. G. Prasad, Sunil Kumar

“…The molecular dynamics simulation studies provide insights into the dynamic behaviour and stability of the PGIP-PG complexes, shedding light on the intricate details of the inhibitory and exhibitory mechanism against the major fungal and bacterial pathogens of G. barbadense, respectively. …”
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Exploring the growth performance, antioxidant capacity, and metabolism of Babylonia areolata in response to yeast selenium supplementation by Yunting Wang, Waqas Ahmed, Sajid Mehmood, Mohsin Mahmood, Lu Wang, Wenjie Ou, Jiannan Li, Jie Yang, Weidong Li, Lianshun Wang

“…These findings provide insights into the nutritional and health benefits of selenium-enriched B. areolata. …”
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Proteomic, metabolomic and lipidomic profiles in community acquired pneumonia for differentiating viral and bacterial infections by Samuel Rischke, Robert Gurke, Ann-Sophie Zielbauer, Nicole Ziegler, Lisa Hahnefeld, Michaela Köhm, Aimo Kannt, Maria JGT Vehreschild, Gerd Geisslinger, Gernot Rohde, Carla Bellinghausen, Frank Behrens, CAPNETZ Study group

“…By providing valuable insights into the molecular characterization of CAP, this study contributes to the improvement of understanding the disease and, ultimately, the development of effective treatment strategies.…”
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Integrating green manure and fertilizer reduction strategies to enhance soil carbon sequestration and crop yield: evidence from a two-season pot experiment by Jun Zhang, Jun Zhang, Jun Zhang, Wei He, Wei He, Wei He, Zheng Wei, Zheng Wei, Yifei Chen, Yifei Chen, Weichun Gao, Weichun Gao

“…This study provides valuable insights into sustainable agricultural practices by demonstrating that incorporating leguminous green manure alongside moderate fertilizer reduction can maintain crop yield, improve soil nutrient availability, and increase organic carbon content, thus supporting reduced reliance on chemical fertilizers and promoting long-term soil fertility and carbon sequestration.…”
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Lateralized differences in power spectra across different frequency bands during NREM sleep in patients with primary insomnia by Jiao Huang, Jiao Huang, Jing Ye, Mingjie Gao, Wentao Gao, Weijia Chen, Yifeng Zhu, Yongbo Wang, Daijin Huang, Yunhui Lv, Hong Shi

“…Primary insomnia was associated with significant fragmented sleep, and an increase in beta1 power was related to the number of awakenings.SignificanceThese findings revealed the hemispheric lateralization characteristics of power spectral disturbances during non-rapid eye movement sleep in primary insomnias and provided valuable insights for selecting electrode placements in future power spectral analyses of primary insomnias.…”
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Unraveling the genetic mysteries of spinal muscular atrophy in Chinese families by Shanshan Gao, Duo Chen, Qianqian Li, Xuechao Zhao, Chen Chen, Lina Liu, Miao Jiang, Zhenhua Zhao, Yanhua Wang, Xiangdong Kong

“…Conclusions This study comprehensively analyzed the genetics of suspected familial SMA cases in the Chinese population, providing insights into the molecular genetic mechanisms of SMA and the utility of various detection techniques. …”
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