Spatial-temporal analysis of flood patterns in semiarid river catchments of SE Iberian Peninsula since CE 1850 by Carlos Sánchez-García, Lothar Schulte

“…A database of the main historical floods reported in written historical documents in the Almanzora, Andarax, Antas and Aguas river basins was compiled, and information on the damage caused by the floods was retrieved from 15 historical archives, allowing an understanding of how floods have behaved over the past 170 years and how they are likely to behave in the near future. New hydrological insights for the region: The river basins of the province of Almería are drained by ephemeral flows mostly related to episodes of heavy rainfall or to long-lasting rainfall attributed to low pressure systems that can persist for several days. …”
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Trend in burden of rheumatoid arthritis in China from 1990 to 2021 by WEN Jiaxin，JIANG Junpeng，FENG Min，SHEN Xiaochen，LI Xiaoyin

“…Objective:To analyze the trend in burden of rheumatoid arthritis (RA) in China from 1990 to 2021, so as to provide insights into reducing the RA burden in China. Methods:Data of Global Burden of Disease Study 2021 were collected, and the incidence, mortality and disability-adjusted life years (DALY) of RA in China from 1990 to 2021 were analyzed and compared with global and different Socio-demographic Index (SDI) regions. …”
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Cohort study evaluating pressure ulcer management in clinical practice in the UK following initial presentation in the community: costs and outcomes by Julian F Guest, Graham W Fuller, Peter Vowden, Kathryn Ruth Vowden

“…Additionally, the cost of managing an unhealed ulcer was 2.4 times more than that of managing a healed ulcer (mean of £5140 vs £12 300 per ulcer).Conclusion This study provides important insights into a number of aspects of PU management in clinical practice in the community that have been difficult to ascertain from other studies, and provides the best estimate available of NHS resource use and costs with which to inform policy and budgetary decisions.…”
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Unraveling the Beneficial Role of Resveratrol in Fructose-Induced Non-Alcoholic Steatohepatitis with a Focus on the AMPK/Nrf2 Signaling Axis by Soha S. Zakaria, Safaa M. Hanafy

“…<i>Conclusions:</i> This study specifically examines resveratrol’s therapeutic effects in a high-fructose diet-induced NASH model, focusing on the AMPK/Nrf2 signaling pathway to address oxidative stress and autophagy, providing novel insights into its molecular mechanism of action. Resveratrol reduces NASH by boosting autophagy and activating the AMPK/Nrf2 pathway. …”
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Spatiotemporal air quality prediction using stochastic advection–diffusion model for multimodal data fusion by Byeongseong Choi, Michelle A Hummel

“…Data fusion approaches that integrate data from multiple sources can complement existing observation networks and reveal insights that single-sensor data might miss to better manage pollutant exposure risks. …”
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Online cognitive–behavioural therapy for traumatically bereaved people: study protocol for a randomised waitlist-controlled trial by Jos de Keijser, Lonneke Lenferink, Maarten Eisma, Geert Smid, Paul Boelen

“…This study will provide new insights in the effectiveness of online CBT for traumatically bereaved people. …”
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Mapping forest-agroforest frontiers in the Peruvian Amazon with deep learning and PlanetScope satellite data by Wanting Yang, Daniel Ortiz-Gonzalo, Xiaoye Tong, Dimitri Gominski, Rasmus Fensholt

“…Our findings contribute to distinguishing agroforests from forests at a large scale, providing insights into previously undetected tree-covered land uses and thus informing on sustainable ecosystem management. …”
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Understanding molecular mechanisms of vertebral number of variations on Mongolian sheep using candidate genes analysis by Chimgee Purev, Huiguang Wu, Khosbayar Lkhagva, Odbayar Tumendemberel

“…These results provide valuable insights into the genetic basis of meat production traits in Bayantsagaan sheep and may contribute to the development of more efficient breeding strategies.…”
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A post-marketing pharmacovigilance study of triazole antifungals: adverse event data mining and analysis based on the FDA adverse event reporting system database by Yalan Tian, Min Jin, Hong Ning

“…BackgroundTo explore and analyze post-marketing adverse drug event (ADE) signals for voriconazole, posaconazole, and isavuconazole, and to compare the safety differences among the three drugs, aiming to provide insights for rational clinical use.MethodsUsing the Open Vigil 2.1 online tool, extract adverse drug event (ADE) report data for voriconazole, posaconazole, and isavuconazole from the U.S. …”
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Color Confinement, Hadron Dynamics, and Hadron Spectroscopy from Light-Front Holography and Superconformal Algebra by Stanley J. Brodsky

“…This approach also leads to insights into the physics underlying hadronization at the amplitude level. …”
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Copper homeostasis and neurodegenerative diseases by Yuanyuan Wang, Daidi Li, Kaifei Xu, Guoqing Wang, Feng Zhang

“…Ultimately, we collate evidence that copper homeostasis may function in the underlying etiology of several neurodegenerative diseases and offer novel insights into the potential prevention and treatment of these diseases based on copper homeostasis.…”
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Pressure-driven polymeric membrane performance prediction, new membrane dimensionless number, and considerations for effective membrane design, selection, testing, and operation by Alexander R. Anim-Mensah, Alexander R. Anim-Mensah

“…This model paves the way for advancing polymeric pressure-driven membrane research and offers new insights into membrane selection, testing, design, and operation.…”
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In Vitro Induction of Hypertrophic Chondrocyte Differentiation of Naïve MSCs by Strain by Thomas Jörimann, Priscilla Füllemann, Anita Jose, Romano Matthys, Esther Wehrle, Martin J. Stoddart, Sophie Verrier

“…Overall, this study indicates that mechanical loading alone drives naïve MSCs towards a hypertrophic chondrocyte differentiation path. These insights underscore the critical role of mechanical forces in MSC differentiation and have significant implications for bone healing, regenerative medicine strategies and rehabilitation protocols.…”
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Comprehensive Analysis of the Immune Response to SARS-CoV-2 Epitopes: Unveiling Potential Targets for Vaccine Development by Huixiong Deng, Yanlei Li, Gefei Wang, Rui Li

“…Our analysis uncovered key immune responses linked to preventing viral infection and viral clearance, emphasized areas of interest for broad-spectrum SARS-CoV-2 vaccine development, and offered insights for future research and clinical applications.…”
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A successful case study of using HCl and viscoelastic diverting acid systems for carbonate matrix acidizing in an oil well with optimized predictive model by Javad Mahdavi Kalatehno, Ehsan Khamehchi, Mostafa Keihanikamal, Fatemeh Yousefmarzi, Matin Dargi, Peyman Daneshfar

“…The developed models, with correlation coefficients exceeding 0.96, further validated the accuracy of the optimization process and provided valuable insights into the critical factors influencing acidizing performance. …”
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Exploring the use, perceptions, and challenges of mini-implants in orthodontic practice: a survey study by Tinela Panaite, Carina Balcos, Carmen Savin, Nicolae Daniel Olteanu, Nikolaos Karvelas, Cristian Romanec, Raluca-Maria Vieriu, Alice Chehab, Irina Zetu

“…By comparing documented literature with real-world practices, the study identifies both correlations and discrepancies, providing valuable insights into the practical application of mini-implants in orthodontic treatments.…”
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Preparation of Zwitterionic Sulfobetaines and Study of Their Thermal Properties and Nanostructured Self-Assembling Features by Yenglik Amrenova, Arshyn Zhengis, Arailym Yergesheva, Munziya Abutalip, Nurxat Nuraje

“…These results demonstrate that precise modifications of the chemical structure, specifically in the linear, imidazole, and pyridine moieties, enable fine control over the thermal properties and self-assembly behavior of polyzwitterions. Such insights are essential for tailoring polymer properties for targeted applications in filtration membranes, drug delivery systems, and solid polymer electrolytes, where thermal stability and self-assembly play crucial roles.…”
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Dynamic Mechanical Response, Cracking Behavior, and Stress Intensity Factors of Cement Mortar Specimens with Open and Closed Flaws by Qizhi Wang, Fangshi Shi, Xiao Wang, Qingling Meng, Xing Li, Jinbo Song, Chang-yi Yu

“…The findings in this work provide some basic insights into the cracking mechanism of rock with open and closed flaws under dynamic loading conditions.…”
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Temporal associations between microclimate, adult Aedes mosquito indices, and dengue cases at the residence level in Malaysia: Implications for targeted interventions. by Nur Athen Mohd Hardy Abdullah, Nazri Che Dom, Biswajeet Pradhan, Siti Aekball Salleh, Rahmat Dapari

“…The findings offer valuable insights for decision-makers, providing them with evidence-based information to implement targeted interventions and strategies aimed at controlling Aedes mosquito populations and mitigating the spread of dengue virus infections.…”
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ASSESSING THE IMPACT OF ACIDIC DRINKS ON THE STRUCTURAL INTEGRITY OF ENAMEL AND THEIR CONSEQUENCES FOR DENTAL AESTHETICS by Berivan Laura Rebeca Buzatu, Roxana Buzatu, Atena Galuscan, Delia Abrudan Luca, Ruxandra Sava Rosianu, Octavia Balean, Titus Vlase, Daniela Jumanca

“…Results: The results of this study will contribute to a deeper understanding of enamel erosion caused by acidic beverages, offering valuable insights for both dental professionals and individuals aiming to protect their enamel from deterioration. …”
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