Emergency Medicine and Rapid Response Virtual Team (EM-RRVT): Insights from the Hajj 1445/2025 Experience by Sharafaldeen Bin Nafisah, Abdullah Mohammed Alhutrushi, Atheer Abdullah Abanmi, Mohammed Hassan Abujamous, Loay Hammad Sabbah, Layla Sulaiman AlSalehi, Ziyad Khater Alzahrani, Abdullah Abdulaziz Alwabel, Abdulaziz Suliman Alhomod, Mona Sahman Alsubaie

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Case Report: Severe acute pancreatitis accompanied by gastric mucosal exfoliation hemorrhage: clinical alerts and novel insights by Yanquan Liu, Hehui Zhang, Minjuan Zeng, Jian Luo, Yun Lai, He Huang, Qinglin Xu, Yuan Liu

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Insights into the toxic impact of long-term exposure to diethyl phthalate on commercially important species Catla (Labeo catla) by Satabdi Ganguly, Basanta Kumar Das, Anupam Adhikari, Subir Kumar Nag

“…Conclusions This pioneering study could provide detailed insight into the endocrine disruptive potential of DEP in fish, as evidenced by its impact at multiple endpoints, even at low doses after 30 days of exposure. …”
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How do Spanish consumers perceive different lettuce cultivation systems? Insights from explicit and implicit methods by Juan Diego Torres, Sara R. Jaeger, Patricia Puerta, Amparo Tárrega

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Intraspecific epigenomics divergence in brown bears (Ursus arctos): insights from genome-wide DNA methylation patterns by Paolo Colangelo, Paolo Colangelo, Ian Marc Bonapace, Laura Gramolini, Emanuela Solano, Emanuela Solano, Elisa Desiato, Paolo Franchini, Leonardo Gentile, Roberto Guadagnini, Oddmund Kleven, Jonas Kindberg, Jonas Kindberg, Alexander Kopatz, Paolo Ciucci

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Advancing allergic rhinitis research through phenome-wide association studies: Insights from known genetic loci by Xingling Tan, MD, Zhouyouyou Xiao, MB, Yao Wen, MD, Han Liu, MD, Wei Yu, MD

“…By revealing new associations and shared genetic pathways, our findings provide valuable insights into the pathophysiology of AR and pave the way for more effective targeted interventions to manage AR and its related diseases.…”
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Cutting-Edge Advances in Anticancer Therapies: Insights from the Third Edition of the Special Issue “Novel Anticancer Strategies” by Hassan Bousbaa

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Structural insights into the LGR4-RSPO2-ZNRF3 complexes regulating WNT/β-catenin signaling by Lu Wang, Fangzheng Hu, Qianqian Cui, Huarui Qiao, Lingyun Li, Tengjie Geng, Yuying Li, Zengchao Sun, Siyu Zhou, Zhongyun Lan, Shaojue Guo, Ying Hu, Jiqiu Wang, Qilun Yang, Zenan Wang, Yuanyuan Dai, Yong Geng

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New Insights into Fertilisation with Animal Manure for Annual Double-Cropping Systems in Nitrate-Vulnerable Zones of Northeastern Spain by Dolores Quilez, Monica Guillén, Marta Vallés, Arturo Daudén, Beatriz Moreno-García

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Tackling local environmental challenges with livelihoods strategies: insights from small-scale farmers in the vulnerable region of Ghana by Bright Osei Boateng, Henry Mensah, Eric Kwame Simpeh, Patrick Opoku, Lilian Amponsaa Boateng

“…While there is a broad understanding of climate change's effects on agriculture, there is a need for deeper insights into the key determinants and preferences influencing SSFs' adaptation strategies in vulnerable regions to better inform agricultural policy and planning. …”
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Prognostic significance of lymph node ratio in esophageal squamous cell carcinoma: insights from the South Asian population by Sajida Qureshi, Waqas Ahmad Abbasi, Hira Abdul Jalil, Saba Mughal, Muhammad Saeed Quraishy

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A Novel Immune-Related Three-Gene Signature and Immune Infiltration Insights in Psoriasis and Chronic Kidney Disease by Yin T, Zhang T, Ma L

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Unravelling Secondary Brain Injury: Insights from a Human-Sized Porcine Model of Acute Subdural Haematoma by Thomas Kapapa, Vanida Wernheimer, Andrea Hoffmann, Tamara Merz, Fabia Zink, Eva-Maria Wolfschmitt, Oscar McCook, Josef Vogt, Martin Wepler, David Alexander Christian Messerer, Claire Hartmann, Angelika Scheuerle, René Mathieu, Simon Mayer, Michael Gröger, Nicole Denoix, Enrico Clazia, Peter Radermacher, Stefan Röhrer, Thomas Datzmann

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Fosab, but not fosaa, plays important role in learning and memory in fish—insights from zebrafish gene knockout study by Qiuling Wang, Qiuling Wang, Qiuling Wang, Lixin Zhang, Lixin Zhang, Lixin Zhang, Chenyuan Zhu, Chenyuan Zhu, Chenyuan Zhu, Ke Lu, Ke Lu, Ke Lu, Jiaqi Wu, Jiaqi Wu, Jiaqi Wu, Xu-Fang Liang, Xu-Fang Liang, Xu-Fang Liang

“…For the first time, we illustrated the role of fosaa and fosab in learning and memory via c-fos knockout in fish, which can provide new insights into environmental adaptation.…”
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Insights into Reaction Conditions for Selective Catalytic Reduction of NOx with a MnAl Oxide Catalyst at Low Temperatures by Hongjian Zhu, Luming Qiu, Rui Wang

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THE INTERPLAY BETWEEN ECONOMIC FREEDOM AND THE SHADOW ECONOMY IN AN EASTERN EUROPEAN COUNTRY: INSIGHTS FROM PRINCIPAL COMPONENT ANALYSIS by MASTAC LAVINIA, VANCEA DIANE PAULA CORINA

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Insights into the signal transduction pathways of mouse lung type II cells revealed by transcription factor profiling in the transcriptome by Chilakamarti V. Ramana

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Deciphering the mechanisms of long non-coding RNAs in ferroptosis: insights into its clinical significance in cancer progression and immunology by Shengming Ou, Xiaoya Nie, Xiangyu Qiu, Xin Jin, Geyan Wu, Rongxin Zhang, Jinrong Zhu

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HA198 mutations in H9N2 avian influenza: molecular dynamics insights into receptor binding by Rui Zhu, Rui Zhu, Rui Zhu, Jie Wu, Ruiying Chen, Mo Zhou, Mo Zhou, Mo Zhou, Shinuo Cao, Shinuo Cao, Shinuo Cao, Zhi Wu, Zhi Wu, Zhi Wu, Ligang Wang, Lei Zhang, Shanyuan Zhu, Shanyuan Zhu, Shanyuan Zhu

“…Interestingly, residue 198 interacted with the α2,6 SA via water bridges but had with showed minimal direct interaction with α2,3 SA.DiscussionThis study provides new insights into the molecular basis of receptor specificity, binding affinity, and antigenic drift in H9N2 viruses, highlighting the critical role of HA 198 mutations in regulating host adaptation. …”
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Achieving inter- and transdisciplinarity in Ecohealth: insights from a rodent-borne disease project in a polycrisis era by Isabelle Arpin, Clémence Massart, Vincent Bourret, Guillaume Castel, Valeria Carolina Colombo, Jana Eccard, Jasmin Firozpoor, Maciej Grzybek, Heikki A. Henttonen, Herwig Leirs, Andrew McManus, Ben Roche, Tarja Sironen, Vincent Sluydts, Peter Stuart, Annetta Zintl, Nathalie Charbonnel

“…Addressing rodent-borne diseases, a less wicked problem, limited engagement potential but enabled constructive dialog with local actors. These insights are vital for addressing variably wicked problems in a polycrisis era. …”
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