Evaluating the Efficacy of a Serious Game to Deliver Health Education About Invasive Meningococcal Disease: Clustered Randomized Controlled Equivalence Trial by Lauren Bloomfield, Julie Boston, Martin Masek, Lesley Andrew, Donna Barwood, Amanda Devine

“…Improvements were retained in both groups 3 months after the initial intervention (median correct score: 11/16 in the intervention group; 12/16 in the control group; P=.86), demonstrating the efficacy of MIApp to deliver health education about IMD transmission and protection, although response rates in the follow-up cohort were low (255/788, 32.4%). …”
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Global, regional, and national epidemiology of childhood neuroblastoma (1990–2021): a statistical analysis of incidence, mortality, and DALYsResearch in context by Jusen Nong, Cheng Su, Changhua Li, Congjun Wang, Wei Li, Yong Li, Peng Chen, Yanqiang Li, Zihao Li, Xinjin She, Zuxin Yuan, Sentian Liu, Chao Chen, Qian Liao, Yige Luo, Bo Shi

“…Interpretation: The global trends for incidence, mortality, and DALYs related to pediatric neuroblastoma initially increased and then decreased, although an overall increasing trend was observed. …”
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Free Fatty Acids in CSF and Neurological Clinical Scores: Prognostic Value for Stroke Severity in ICU by Sayed Gaber, Sherine Ibrahim ElGazzar, Mahmoud Qenawi, Nora Ismail Mohamed Abbas

“…Introduction. Brain ischemia initiated significant increase in FFAs in animal studies. …”
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Professional Action Competence in Education for Sustainability Among Pre-service Physical Education Teachers: A Mixed Method Approach by Valérian Cece, Thomas Royet, Olivier Vors, Vanessa Lentillon-Kaestner

“…These findings offer concrete perspectives in terms of initial and in-service training for physical education teachers. …”
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Standards in Neurological Rehabilitation, June 1997 by Michael P. Barnes, European Federation of Neurological Societies Task Force

“…We firmly endorse international co-operation in this field and are happy to co-operate with any international organization in order to develop such links for clinical, educational or research initiatives. (8) The Task Force encourages individual countries to produce a document summarizing their own situation with regard to these standards and to produce a timetable for action to improve their situation. …”
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Endothelial Dysfunction and Oxidative Stress in Patients with Severe Coronary Artery Disease: Does Diabetes Play a Contributing Role? by Alexandra Maria Boieriu, Cezar Dumitrel Luca, Carmen Daniela Neculoiu, Alina Bisoc, Diana Țînț

“…<i>Background and Objectives</i>: Endothelial dysfunction (ED) and oxidative stress play major contributions in the initiation and progression of atherosclerosis. Diabetes is a pathological state associated with endothelial damage and enhanced oxidative stress. …”
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Identification of SLC35A1 as an essential host factor for the transduction of multi-serotype recombinant adeno-associated virus (AAV) vectors by Xiujuan Zhang, Siyuan Hao, Zehua Feng, Kang Ning, Cagla Aksu Kuz, Shane McFarlin, Donovan Richart, Fang Cheng, Ander Zhang-Chen, Richenda McFarlane, Ziying Yan, Jianming Qiu

“…These results underscore the crucial role of SLC35A1 in intracellular trafficking beyond the initial cell attachment of rAAV.…”
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Metrics for Evaluating Telemedicine in Randomized Controlled Trials: Scoping Review by Yuka Sugawara, Yosuke Hirakawa, Masao Iwagami, Ryota Inokuchi, Rie Wakimizu, Masaomi Nangaku

“…ResultsOf the 2275 articles initially identified, 79 were included in the final analysis. …”
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Carbon stock dynamics of forest to oil palm plantation conversion for ecosystem rehabilitation planning by D. Frianto, E. Sutrisno, A. Wahyudi, E. Novriyanti, W.C. Adinugroho, A.S. Yunianto, H. Kurniawan, H. Khotimah, A. Windyoningrum, I.W.S. Dharmawan, H.L. Tata, S. Suharti, H.H. Rachmat, E.M. Lim

“…Additionally, it highlights their role in ecosystem restoration initiatives and the better management of forest peatland regions.METHODS: A spatial analysis was conducted on Landsat 5 and 8 satellite images by using shapefile data stored within the Google Earth Engine platform. …”
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A comparative study of hospitalization costs of TKA inpatients before and after National Volume-based Procurement in Guangdong, China: an interrupted time-series analysis by Anqi Li, Gongduan Li, Dong Han, Manru Fu, Jinghui Chang, Jinghui Chang

“…After implementation (from May 1, 2022 to December 26, 2023), the total expenses (β3=−106.95, p&lt;0.05), consumables costs (β3= − 65.05, p&lt;0.05), diagnostic fees (β3= − 22.44, p &lt; 0.05), treatment fees (β3= − 28.01, p &lt; 0.05), total Chinese medicine costs (β3= − 9.98, p &lt; 0.05), and blood and blood products costs (β3= − 5.88, p&lt;0.05) continued to decrease.ConclusionThe volume-based procurement policy in Guangdong, China has shown initial effectiveness. After it was implemented, total expenses, consumables costs, and self-financed expenses decreased. …”
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Fluid Inclusions and H-O-C-S Isotopes of the Wushan Copper Polymetallic Deposit in the Suizao Area, Hubei Province: Implications for Ore Genesis by Pan-Pan Niu, Shao-Yong Jiang, Suo-Fei Xiong, Qi-Sheng Hu, Tian-liang Xu

“…Combined with C-H-O isotopic compositions, the initial ore-forming fluid is likely magmatic water, but with the addition of meteoric water in the late stage. …”
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Effectivity of prebiotic mannan oligosaccharides as the immunity enhancer and growth response on whiteleg shrimp Litopenaeus vannamei against white spot disease by Linuwih Aluh Prastiti, Munti Yuhana, Widanarni, Widanarni

“…Shrimps (Litopenaeus vannamei) (the initial average weight was 3.416±0.064 g) were fed at satiation, three times a day. …”
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Predictive value of the systemic immune–inflammation index for outcomes in large artery occlusion treated with mechanical thrombectomy—a single-center study by Ao Qian, Longyi Zheng, Hui He, Jia Duan, Shuang Tang, Wenli Xing

“…Multivariate analysis demonstrated that heightened SII was significantly related to HT (odds ratio [OR]: 1.061, 95% confidence interval [CI]: 1.035–1.086, p &lt; 0.001), MBE (OR: 1.074, 95% CI: 1.045–1.103, p &lt; 0.001), adverse function (OR: 1.061, 95% CI: 1.031–1.092, p &lt; 0.001), and mortality (OR: 1.044, 95% CI: 1.018–1.070, p = 0.001), after adjusting sex, age, Glasgow Coma Scale (GCS) score at admission, initial National Institutes of Health Stroke Scale (NIHSS) score, baseline Alberta Stroke Program Early Computed Tomography Score (ASPECTS), present HMCAS, occluded vessel region, collateral score and successful revascularization. …”
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The generation and evaluation of TKO/hCD55/hTM/hEPCR gene-modified pigs for clinical organ xenotransplantation by Guoli Huai, Yong Wang, Jiaxiang Du, Zhenhui Cheng, Yuxuan Xie, Jia Zhou, Hongmei Tang, Yanyan Jiang, Xiangyang Xing, Shaoping Deng, Dengke Pan, Dengke Pan, Dengke Pan

“…However, the optimal combination of genetic modifications and their expression levels for initial clinical trials remains unclear. This study investigates the generation of TKO/hCD55/hTM/hEPCR (6GE) pigs and evaluates their compatibility with human immune and coagulation systems.MethodsThe 6GE pigs were generated through iterative genome editing and F1 generation breeding. …”
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Main topics in assisted reproductive market: A scoping review. by Janaina Ferreira Aderaldo, Beatriz Helena Dantas Rodrigues de Albuquerque, Maryana Thalyta Ferreira Câmara de Oliveira, Mychelle de Medeiros Garcia Torres, Daniel Carlos Ferreira Lanza

“…<h4>Conclusions</h4>The formation of topics by semantic similarity proved to be an initial path for the elaboration of in-depth studies on the dynamics between several factors, for this, we present the panel classifying main terms into factors (demand, pent-up demand, or distributive) or ART market consequences. …”
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Large-scale manufacturing and characterization of CMV-CD19CAR T cells by Stephen J Forman, Xiuli Wang, Ryan Urak, Miriam Walter, Min Guan, Tianxu Han, Vibhuti Vyas, Sheng-Hsuan Chien, Brenna Gittins, Mary C Clark, Sally Mokhtari, Angelo Cardoso, Don J Diamond, John Zaia, Ryotaro Nakamura

“…The final products passed release criteria for clinical use.Conclusions We demonstrated the feasibility of our large-scale platform for generating CMV-CD19CAR T cells for clinical application. We plan to initiate a clinical trial at City of Hope using CMV-CD19CAR T cells for patients with intermediate/high-grade B cell non-Hodgkin’s lymphoma immediately after autologous hematopoietic cell transplantation followed by vaccination with a novel CMV vaccine based on Modified Vaccinia Ankara (Triplex) 28 days and 56 days post-T cell infusion.…”
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Risk factors for methotrexate treatment failure in tubal ectopic pregnancy: a retrospective cohort study by Linru Fu, Xinyan Liu, Zhao Tian, Zhe Du, Xinyi Wang, Xiuqi Wang, Xiaodong Li, Tao Xu, Zhijing Sun

“…Patients received MTX treatment initially, with dosing intervals and protocols varying according to clinical practice. …”
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Comparing Deep Learning models for mapping rice cultivation area in Bhutan using high-resolution satellite imagery by Biplov Bhandari, Timothy Mayer

“…This study focuses on Paro, one of the top rice-yielding districts in Bhutan, and employs publicly available Norway’s International Climate and Forest Initiative (NICFI) high-resolution satellite imagery from Planet Labs. …”
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Enhancing Diagnostic Accuracy of Lung Nodules in Chest Computed Tomography Using Artificial Intelligence: Retrospective Analysis by Weiqi Liu, You Wu, Zhuozhao Zheng, Mark Bittle, Wei Yu, Hadi Kharrazi

“…ConclusionsThe AI system enhanced lung nodule detection, offering the possibility of earlier disease identification and timely intervention. Nevertheless, the initial reduction in accuracy underscores the need for standardized diagnostic criteria and comprehensive training for radiologists to maximize the effectiveness of AI-enabled diagnostic systems.…”
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Awake prone positioning and ventilation distribution as assessed by electric impedance tomography in patients with non-COVID-19 acute hypoxemic respiratory failure: A prospective p... by Jingjing Wang, Changxing Chen, Zhanqi Zhao, Puyu Deng, Chenchen Zhang, Yu Zhang, Hui Lv, Daonan Chen, Hui Xie, Ruilan Wang

“…ROX showed a significant increase after initiation of APP {median (interquartile range [IQR]): T0: 7.5 (6.0–10.1) vs. …”
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