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24141
Resveratrol contributes to NK cell-mediated breast cancer cytotoxicity by upregulating ULBP2 through miR-17-5p downmodulation and activation of MINK1/JNK/c-Jun signaling
Published 2025-02-01“…ULBP2-NKG2D ligation initiates NK cell activation and subsequent targeted elimination of cancer cells. …”
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24142
Which patients received a ReSPECT form, what was documented and what were the patient outcomes? A protocol for a retrospective observational study investigating the impact of the C...
Published 2022-07-01“…Introduction Recommended Summary Plan for Emergency Care and Treatment (ReSPECT) is a UK advance care planning (ACP) initiative aiming to standardise the process of creating personalised recommendations for a person’s clinical care in a future emergency and therefore improve person-focused care. …”
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24143
Shared Genes and Pathways in Ulcerative Colitis and Ankylosing Spondylitis: Functional Validation and Implications for Diagnosis
Published 2025-02-01“…Thus, in the current study, we aimed to investigate the shared genes and relevant mechanisms in UC and AS.Methods: Using datasets for UC (GSE113079) and AS (GSE1797879), we initially identified differentially expressed genes (DEGs) through differential expression analysis. …”
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24144
Advancing Horticultural Crop Loss Reduction Through Robotic and AI Technologies: Innovations, Applications, and Practical Implications
Published 2024-01-01“…However, the implementation of these technologies face challenges such as high initial costs, the need for technical expertise, and the integration of various data sources. …”
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24145
Rapid response electroencephalography decreases time to seizure diagnosis in pediatric acute care patients
Published 2025-02-01“…The bedside provider was able to initiate EEG monitoring, successfully diagnose patients using the Brain Stethoscope, and decrease delays associated with technician availability. …”
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24146
Short Term Outcome of High Dose Dexamethasone Versus Prednisone In Children With Acute Immune Thrombocytopenic Purpura: A Single Center Trial
Published 2025-01-01“…The main symptom was epistaxis in 30(50%) of cases, followed by purpura in 18(30%), gum bleeding in 10(16.6%), and subconjunctival hemorrhage in 2(3.4%). Initial mean platelet count in HD-DXM and PDN was 5.4± 2.9 x 103 μl and 5.2 ± 4.2 x103 μl (p=0.444). …”
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24147
Impact of rock mineralogy on reactive transport of CO2 during carbon sequestration in a saline aquifer
Published 2025-01-01“…Quartz exhibits minimal dissolution, while calcite plays a crucial role, initially dissolving due to low pH and later precipitating after around 300 years. …”
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24148
On-Site Evaluation and Improvement Strategies of Radiation Occupational Hazard Prevention and Control Effectiveness in Medical Institution Construction Projects
Published 2025-02-01“…New DR performance testing standards introduced specialized testing items, such as dark noise, detector dose indication (DDI), and signal transmission characteristics (STP), which presented initial challenges due to the unavailability of pre-processing images in some manufacturers’ products. …”
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24149
‘Subtle Instrument of Music’: Translating the Sound and Appearance of Decadence in Wilde’s Salomé
Published 2017-11-01“…Wilde called the play his ‘first venture to use for art that subtle instrument of music, the French tongue’ (Hart-Davis 331). Its initial performance in England was prohibited and it was not produced on stage until 1896; even then, it opened in Paris and not London. …”
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24150
Apoptotic Vesicles Attenuate Acute Lung Injury via CD73-Mediated Inhibition of Platelet Activation and NETosis
Published 2025-01-01“…Additionally, the role of CD73 in mediating these effects was thoroughly investigated.Results: ApoVs inhibit platelet activation, thereby impeding the infiltration of neutrophils into the lung and the initiation of NETosis, ultimately alleviating ALI. Remarkably, apoVs were enriched with CD73, which was critical for apoV-mediated repression of platelet activation and neutrophil NETosis, as well as the therapeutic effects observed in lung injury.Conclusion: This study reveals that apoVs inhibit platelet activity and neutrophil NETosis via CD73, offering an innovative and effective cell-free therapeutic strategy for ALI/ARDS. …”
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24151
Apheresis for the treatment of relapses in MS and NMOSD: reduced antibody reactivities, gene expression changes and potential clinical response indicators
Published 2025-01-01“…The data were compared with regard to changes under therapy and with regard to differences between clinical responders and non-responders.ResultsThe initial therapy with methylprednisolone had no significant effect on immunoglobulin levels and (auto)antibody reactivities (nmax=27 MS patients). …”
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24152
Statistical Downscaling Method for Vegetation Optical Depth Based on NDVI
Published 2025-01-01“…A downscaling method that utilizes classification residual correction is proposed. The method initially establishes an equation that represents the difference between NDVI and VOD before and after downscaling. …”
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24153
The Use of AI in Mental Health Services to Support Decision-Making: Scoping Review
Published 2025-01-01“…The searches were restricted to peer-reviewed articles published in English after 2011. The initial screening at the title and abstract level was conducted by 2 reviewers, followed by full-text screening based on the inclusion criteria. …”
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24154
Experiences and Perspectives of Medication Information and Use Among Arabic-Speaking Migrant Women in Sweden: A Multistage Focus Group Study
Published 2025-02-01“…This study aims to explore Arabic-speaking migrant women’s experiences and perspectives on medication information and use.Methods: This study was part of the Equal Health program, a health promotion initiative established in socially vulnerable areas to address health inequities. …”
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24155
Identification of Potential miRNA-mRNA Regulatory Network Contributing to Parkinson’s Disease
Published 2022-01-01“…Thus, the miRNA-mRNA regulatory network was initially constructed and has the potential to provide novel insights into the pathogenesis and treatment of PD.…”
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24156
Risk factors for low resilience among Grade 10 adolescents in the Gampaha district, Sri Lanka: a case-control study
Published 2025-01-01“…In multivariable logistic regression analysis, out of 24 independent variables entered initially into the model, only 9 were retained in the final model. …”
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24157
Transcriptomic Profiling and Tumor Microenvironment Classification Reveal Unique and Dynamic Immune Biology in HIV-Associated Kaposi Sarcoma
Published 2025-01-01“…Notably, HIV-negative KS samples showed alterations in NK cell-mediated immunity and cytotoxic response pathways, whereas HIV-positive samples exhibited changes in growth regulation and protein kinase activity pathways at the time of initial diagnosis. The gene expression of immune checkpoints, including CD274 (PD-L1) and PDCD1LC2 (PD-L2), was comparable between HIV-positive and HIV-negative KS samples at diagnosis. …”
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24158
NL-Augmenter: A Framework for Task-Sensitive Natural Language Augmentation
Published 2023-04-01“…We describe the framework and an initial set of 117 transformations and 23 filters for a variety of NL tasks annotated with noisy descriptive tags. …”
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24159
AI Chatbots and Cognitive Control: Enhancing Executive Functions Through Chatbot Interactions: A Systematic Review
Published 2025-01-01“…The criteria aligned with the study objectives, ensuring a focus on AI chatbots and the impact of conversational agents on executive function. The initial collection totaled <i>n</i> = 115 articles; however, the eligibility requirements led to the final selection of <i>n</i> = 10 studies. …”
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24160
Magnitude of female child sexual abuse in Ethiopia: A systematic review and meta-analysis
Published 2025-01-01“…Results: A total of 1230 research articles were initially identified for this systematic review and meta-analysis. …”
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